KEGG   Equus caballus (horse): 100055366Help
Entry
100055366         CDS       T01058                                 

Gene name
CAD
Definition
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
Orthology
K11540  
carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:6.3.5.5 2.1.3.2 3.5.2.3]
Organism
ecb  Equus caballus (horse)
Pathway
Pyrimidine metabolism
Alanine, aspartate and glutamate metabolism
Metabolic pathways
Module
Uridine monophosphate biosynthesis, glutamine (+ PRPP) => UMP
Brite
KEGG Orthology (KO) [BR:ecb00001]
 Metabolism
  Nucleotide metabolism
   00240 Pyrimidine metabolism
    100055366 (CAD)
  Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    100055366 (CAD)
Enzymes [BR:ecb01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.3  Carboxy- and carbamoyltransferases
    2.1.3.2  aspartate carbamoyltransferase
     100055366 (CAD)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.2  In cyclic amides
    3.5.2.3  dihydroorotase
     100055366 (CAD)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.5  Carbon-nitrogen ligases with glutamine as amido-N-donor
    6.3.5.5  carbamoyl-phosphate synthase (glutamine-hydrolysing)
     100055366 (CAD)
Peptidases [BR:ecb01002]
 Cysteine Peptidases
  Family C26: gamma-glutamyl hydrolase family
   100055366 (CAD)
 Metallo Peptidases
  Family M38: beta-aspartyl dipeptidase family
   100055366 (CAD)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
UniProt: 
Position
15
AA seq 2225 aa AA seqDB search
MAALVLEDGSVLRGQPFGAAMSTAGEVVFQTGMVGYPEALTDPSYKAQILVLTYPLVGNY
GIPPDEVDEFGLSKWFESSGIHVAGLVVGECCPTPSHWSAACTLHEWLQQHGIPGLQGVD
TRELTKKLREQGSLLGKLVQDGTDPAALPFLDPNARPLVPEVSIKAPRVFHAGGTPRILA
LDCGLKYNQIRCLCQRGAEVTVVPWDHVLDSQEYEGLFLSNGPGDPASYPSVVSTLSRVL
SEPNPRPVFGICLGHQLLALAIGAKTYKMRYGNRGHNQPCLLVGSGRCFLTSQNHGFAVE
TDSLPVGWLPLFTNANDHSSEGIVHDSLPFFSVQFHPEHRAGPSDMELLFDIFLETVKEA
TAGNPGGQTVRERLAERLCPRGIPTPGSGLPPPRKVLILGSGGLSIGQAGEFDYSGSQAI
KALKEENIQTLLINPNIATVQTSQGLADKVYFLPITSHYVTQVIRNERPDGVLLTFGGQT
ALNCGVELTRAGVLARYGVRVLGTPVKTIELTEDRRAFASRMAEIGEHIAPSEAANSLEQ
AQAAAERLGYPVLVRAAFALGGLGSGFASNKEELSALVATAFAHTSQVLIDKSLKGWKEI
EYEVVRDAYGNCVTVCNMENLDPLGIHTGESIVVAPSQTLNNREYQLLRQTAIKVTQHLG
IVGECNVQYALNPESEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLALGIPLPELSN
SVTGGTAAFEPSLDYCVVKIPRWDLSKFLRVSTKIGSCMKSVGEVMGIGRSFEEAFQKAL
RMVDENCAGFDHTVKPVSDMELETPTDKRIFVVAAALWAGYSVERLYELTRIDRWFLHRM
QRIIAHTQLLEQHRGQPLPQDLLHQAKRLGFSDKQIALAVLSTELAVRKLRQELGICPAV
KQIDTVAAEWPAQTNYLYLTYWGTSHDLTFRTPHVLVLGSGVYRIGSSVEFDWCAVGCIQ
QLRKMGYKTIMVNYNPETVSTDYDMCDRLYFDEISFEVVMDIYELENPEGVILSMGGQLP
NNMAMALHRQQCRILGTSPESIDSAENRFKFSRLLDTIGISQPQWRELSDLESARQFCQT
VGYPCVVRPSYVLSGAAMNVAYTDGDLERFLSSAAAVSKEHPVVISKFIQEAKEIDVDAV
ASDGVVAAIAISEHVENAGVHSGDATLVTPPQDITAKTLERIKAIVHAVGQELQVTGPFN
LQLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALATRVIMGEKVEPVGLMTGSGVVG
VKVPQFSFSRLAGADVVLGVEMTSTGEVACFGESRCEAYLKAMLSTGFKIPKKNILLTIG
SYKNKSELLPTVRLLESLGYSLYASLGTADYYNEHGVKVTAVDWHFDEAVDGECPPQRSI
LDQLAENHFELVINLSMRGAGGRRLSSFVTKGYRTRRLAADFSVPLIIDIKCTKLFVEAL
GQIGAAPPLKVHVDCMTSQKLVRLPGLIDVHVHLREPGGTHKEDFASGTAAALAGGVTMV
CAMPNTRPPIIDAPALALAQKLAEAGARCDFALFLGASSENAGTLSAVAGSAAGLKLYLN
ETFSELRLDSVAQWMEHFETWPSHLPIVAHAERQTVAAILMVAQLTQRSVHICHVARKEE
ILLIKAAKARGLPVTCEVAPHHLFLSRDDLERLGPGKGQVRPELGSRQDVEALWENMAVI
DCFASDHAPHTLEEKCGPRPPPGFPGLETMLPLLLTAVSEGRLSLDDLLQRLHHNPRRIF
HLPPQEDTYVEVDLEHEWTVPSYMPFSKAHWTPFEGQKVKGTVRRVVLRGEVAYIDGQVL
VPPGYGQDVRKWPQGAVPQLTPSAPAASEITTTPERPRRGIPGLPDGRFHLPPRIHRASD
PGLPAEEPKDKSARKAAEPELLGTLDGTCYPPPPVPRQASPQNLGTPGLLHPQTSPLLHS
LVGQHILSVQQFTKDQMSHLFNVAHTLRMMVQKERSLDILKGKVMASMFYEVSTRTSSSF
AAAMARLGGAVLSFSEATSSVQKGESLADSVQTMSCYADVVVLRHPQPGAVELAAKHCRR
PVINAGDGVGEHPTQALLDIFTIREELGTVNGMTITMVGDLKHGRTVHSLACLLTQYRVS
LRYVAPPSLHMPPNVWDFVASRGTKQEEFESIEEALPDTDVLYMTRIQKERFGSTQEYEA
CFGQFILTPHIMTRAKKKMVVMHPMPRVNEISVEVDSDPRAAYFRQAENGMYIRMALLAT
VLGRF
NT seq 6678 nt NT seq  +upstreamnt  +downstreamnt
atggcggccctggtgttggaggatgggtcggtcctgcggggccagccctttggggccgct
atgtcgactgccggggaagtggtgtttcaaactggcatggtcggctaccccgaggccctc
actgacccttcctacaaagcacagatcttagtgctgacatatcctctggtcggcaactat
ggcatccccccagatgaagtggatgaattcggtctcagcaagtggtttgaatcctcgggg
atccatgtagcaggactggtggtaggagagtgctgccccacgcccagccactggagtgcc
gcctgcaccctgcacgagtggctgcaacagcatggcatacctggcctgcaaggagtggac
actcgggagctgacgaagaagttacgagagcaagggtctcttctgggaaagctggtccag
gatgggacagatcctgcagccctgccattcttggaccccaatgcccgccccctggtgcca
gaggtctccattaaggctccacgggtattccatgcaggaggtactcctcggatccttgct
ttagactgtggcctcaagtataatcagatccgatgcctgtgccagcgtggggctgaggtc
actgtggtaccgtgggatcacgtgttagacagccaggagtatgagggtctcttcctgagt
aatggccctggtgatcccgcctcctatcccagtgtggtatccacactgagccgtgtctta
tctgagcctaatccccggcctgtcttcgggatctgtctgggacaccaactgttggcctta
gccattggggccaagacttacaagatgagatatgggaaccgcggccataatcagccatgc
ttactggtgggctctgggcgctgctttctgacatcccagaaccatgggtttgctgtggaa
acagactcactgccagtaggctggcttcctctcttcaccaatgccaacgatcattccagt
gaaggcattgtacatgacagcctgcccttcttcagtgtccagtttcacccagagcaccga
gctggcccttcagatatggaacttctttttgatatctttctggaaactgtgaaagaagcc
acagctggaaaccctgggggccagacagttcgagaacggctggctgagcgcctctgtccc
cgtggaattcccaccccaggctcggggcttccaccaccacgaaaggttctgatcctgggc
tcagggggcctctccattgggcaagctggagagtttgactactcaggctctcaggcaatc
aaggccctgaaggaggaaaacatccagacattgctgatcaaccccaacattgccacagtg
cagacctcccaggggctagcagacaaggtctatttccttcccataacatctcactatgta
acccaggtgatccgtaatgagcgcccggatggcgtgttgctgacttttgggggccagaca
gccctgaattgtggtgtggagctcaccagggctggagtgctagctcggtatggggtccgg
gtcctgggtacacctgtgaagaccattgagctgactgaggatcgacgtgcctttgcctca
aggatggcagagatcggagagcatatagcccccagtgaggcggcaaattctcttgaacag
gcccaggcagccgccgagcgattagggtaccctgtgctagtgcgtgcagcctttgccctg
ggtggcctaggctctggctttgcctccaacaaggaggaactctctgctcttgtggccaca
gcttttgcccataccagccaagtgctgatagacaagtccctgaagggatggaaggagatt
gagtatgaggtggtgagagacgcctatggcaactgtgtcacggtgtgtaacatggagaac
ttagacccactgggcatccacactggtgagtccatagtggtggctccgagccagacgctg
aataacagggagtaccagctgctgcggcagacggccatcaaggtgacccagcaccttgga
atcgttggggagtgcaatgtccagtatgccttgaaccccgagtctgagcagtattacatc
atcgaagtgaatgccaggctctcccgcagctctgccctggccagtaaagccacaggctat
ccactggcctatgtggcagccaagctggctttgggcatccctctgcctgagctcagtaac
tcagtgacaggaggaacagcagcctttgaacccagcctggattattgtgtggtgaagatt
cctcgctgggacctcagcaagttcctccgtgtcagcacaaagattggcagctgcatgaag
agcgttggtgaagtcatgggcattgggcgttcttttgaggaggccttccagaaggctctg
cgcatggtggatgagaactgtgcgggctttgatcacacggtaaagccagtcagtgatatg
gagttggagactccaacagataagcggatcttcgtggtggcagctgctctgtgggctggc
tactcagtggagcgcctgtacgaactcacacgcatcgatcggtggttcctgcaccgaatg
cagcggatcatagcacacacccagctgctggaacaacatcgtggacagcctttgccccaa
gacctgctgcaccaggccaagcgccttggcttctcagacaagcagattgcccttgcggtt
ctgagcacagagctggctgttcgcaagctgcgtcaggaactagggatctgcccagcggtg
aaacagattgacacagttgcagctgagtggccagcccagacaaattatttgtacctaaca
tactggggcaccagccatgacctcacctttcgaacgcctcatgtcctggtccttggctct
ggtgtctaccgtatcggctccagcgttgagtttgactggtgtgctgtgggctgcatccag
cagctccgaaagatggggtataagaccatcatggtgaactacaacccagagacagtcagc
accgactatgacatgtgcgaccgactctactttgatgagatctcttttgaggtggtgatg
gacatctatgagctggagaaccctgaaggcgtgatcctgtcgatgggtggccagctgcct
aacaacatggccatggctttgcatcggcaacagtgccggatactgggcacctcccctgaa
tccatcgactcagctgagaaccgtttcaagttctcccggctccttgacaccattggtatc
agccagcctcagtggagggagctcagtgacctagagtctgctcgccagttctgccaaaca
gtggggtacccttgcgtggtacgcccctcctatgtgctgagtggtgctgctatgaatgtg
gcctacaccgacggggacctggagcgcttcctgagcagcgcagccgccgtctccaaggag
caccctgtggtcatctccaagttcatccaggaggccaaggagattgatgtggatgctgtg
gcctctgatggcgtggtagcagccattgccatctctgagcatgtggagaatgcaggtgtg
cattcaggcgatgccacactggtgaccccaccacaagacatcactgccaaaaccctggag
cggatcaaagccattgtgcatgctgtgggccaggagctacaggtcacgggacccttcaat
ctgcagctcattgccaaggacgaccagctgaaagttatcgaatgcaacgtgcgtgtctct
cgctccttccccttcgtctccaagacactaggcgtggacctagtagccttggccacacgg
gtcatcatgggcgaaaaagtggaacctgtggggctcatgactggctctggagtcgtgggg
gtaaaggtgccccagttctcattctcccgcttggcgggtgctgatgtggtgttgggtgtg
gagatgaccagtactggggaagtggcctgctttggggagagccgttgcgaggcctacctc
aaggccatgcttagcactggctttaagatccccaagaagaacatcttgctgaccattggc
agctataagaacaagagcgagctgctcccaactgtgcggctgctggagagcctgggctat
agcctctacgccagtctgggcaccgctgactactacaacgagcacggcgtcaaggtaaca
gctgtggactggcactttgacgaggcagtggatggtgagtgcccaccacagcgaagcatc
ttggaccagctggctgagaatcacttcgagctagtgattaacctgtcaatgcgtggggcc
gggggccggcgtctctcttcctttgtcaccaagggctaccgcacccggcgcctggctgct
gacttctccgtgcccctcatcatcgatatcaagtgcaccaaactgtttgtggaggcccta
ggccagatcggggcagcccctcctttgaaggtgcacgttgattgcatgacctcccaaaag
cttgtgcggctacctggactaattgatgtccatgtgcacctgcgggaaccaggtgggaca
cacaaggaggactttgcctcaggcacagctgctgccctggctgggggtgtcactatggtg
tgtgccatgcctaacacccggccccccatcattgatgcccctgctctggccctggcccag
aagctagcagaggctggcgcccgctgtgactttgccttattcctcggagcctcatcagaa
aatgcagggaccctgagcgctgtggctgggtctgctgcagggctgaaactgtacctcaat
gagaccttctcggagctgcggctggacagtgtggcccagtggatggagcacttcgagacc
tggccatcgcacctccccattgtggcccatgcggagcggcagactgtcgccgccatcctt
atggtggctcaactgacccagcgctcagtgcacatatgtcacgtggcacggaaggaggag
atcctgctgattaaagctgcaaaggcacgggggctgccagtgacctgcgaggtggcaccc
caccatctgttcctgagccgcgatgatctggaacgcctggggcccgggaaggggcaggtc
cggcctgaacttggctcccgccaggatgtagaggccctctgggagaacatggctgtcatc
gactgcttcgcctcagaccacgccccccacaccttggaggagaagtgtgggccccggcct
cctcctggcttcccagggctcgagaccatgctgcccttgctgctgacagctgtaagcgag
ggccggctcagcctggacgacctgctgcagcgactgcaccacaatcctcggcgtatcttt
cacctgcccccacaggaggacacctatgtggaggtggatctggagcatgaatggacagtc
cccagctacatgcccttctccaaggcccactggacaccctttgaagggcagaaggtgaag
ggcacagtccgccgtgtagtcctacgaggggaggtcgcctatatcgacgggcaggttctg
gtgcccccaggctatggacaggatgtacgcaagtggcctcagggggcagttccccagctc
acgccctcagcccctgctgccagtgagataaccacgacacccgaaaggccccgccggggc
atcccagggcttcctgatggccgcttccacctgccaccccgaatccaccgagcctctgac
ccaggtctgccagctgaggagccaaaggacaagtctgctcggaaggcagctgagccagag
ctgttgggaacccttgatggcacctgctaccctccacctccagtacctagacaggcatca
ccccaaaacctggggacccctggcctgctgcacccccagacctcacccctgctccactca
ttagtgggccaacacatcctgtccgtccagcagttcaccaaggatcagatgtctcacctg
ttcaatgtggcacacacgctgcgtatgatggtgcagaaggagcggagcctcgacatcctc
aaggggaaagtgatggcctccatgttctacgaagtgagcacacggaccagcagctccttt
gcggcagccatggcccgactagggggcgctgtgctcagcttctcagaagccacgtcctct
gtccagaagggcgaatccctggctgactcagtgcagaccatgagctgctatgccgatgtc
gtcgtgcttcggcacccccagcctggggcagtggagctggcagccaagcactgccggagg
ccagtgatcaatgccggggatggggttggagagcatcccacccaggccttactggacatc
ttcaccatccgggaggagcttgggactgtcaatggcatgacgatcacaatggtgggggac
ctgaagcatggacgcacagtgcattccctggcctgcctgctcacccagtatcgtgtcagc
ctgcgctacgtggcgcctcccagcctgcacatgccaccaaatgtgtgggactttgtggcc
tcccgtggcaccaagcaggaggaatttgagagcattgaggaggcgctgcctgacacagat
gtgctctacatgactcgaatccagaaggaacgctttggctctactcaggagtatgaagct
tgctttggccagtttatactcactccacacatcatgacccgggccaagaagaagatggtg
gtgatgcacccaatgccccgcgtcaatgagataagtgtggaggtggactcagacccccga
gcagcctacttccgccaggccgagaatggcatgtacatacgtatggctctgttagccaca
gtgctgggccgcttctag

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