KEGG   Equus caballus (horse): 100055407Help
Entry
100055407         CDS       T01058                                 

Gene name
PLCB3
Definition
phospholipase C, beta 3 (phosphatidylinositol-specific)
Orthology
K05858  
phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
ecb  Equus caballus (horse)
Pathway
Inositol phosphate metabolism
Metabolic pathways
Rap1 signaling pathway
Calcium signaling pathway
Chemokine signaling pathway
Phosphatidylinositol signaling system
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Wnt signaling pathway
Gap junction
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
Dopaminergic synapse
Long-term depression
Inflammatory mediator regulation of TRP channels
Insulin secretion
GnRH signaling pathway
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Endocrine and other factor-regulated calcium reabsorption
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Alzheimer's disease
Huntington's disease
Chagas disease (American trypanosomiasis)
African trypanosomiasis
Amoebiasis
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Class
Metabolism; Carbohydrate metabolism; Inositol phosphate metabolism [PATH:ecb00562]
Environmental Information Processing; Signal transduction; Rap1 signaling pathway [PATH:ecb04015]
Environmental Information Processing; Signal transduction; Wnt signaling pathway [PATH:ecb04310]
Environmental Information Processing; Signal transduction; Calcium signaling pathway [PATH:ecb04020]
Environmental Information Processing; Signal transduction; Phosphatidylinositol signaling system [PATH:ecb04070]
Cellular Processes; Cell communication; Gap junction [PATH:ecb04540]
Organismal Systems; Immune system; Chemokine signaling pathway [PATH:ecb04062]
Organismal Systems; Endocrine system; Insulin secretion [PATH:ecb04911]
Organismal Systems; Endocrine system; GnRH signaling pathway [PATH:ecb04912]
Organismal Systems; Endocrine system; Estrogen signaling pathway [PATH:ecb04915]
Organismal Systems; Endocrine system; Oxytocin signaling pathway [PATH:ecb04921]
Organismal Systems; Endocrine system; Thyroid hormone synthesis [PATH:ecb04918]
Organismal Systems; Endocrine system; Thyroid hormone signaling pathway [PATH:ecb04919]
Organismal Systems; Endocrine system; Melanogenesis [PATH:ecb04916]
Organismal Systems; Circulatory system; Adrenergic signaling in cardiomyocytes [PATH:ecb04261]
Organismal Systems; Circulatory system; Vascular smooth muscle contraction [PATH:ecb04270]
Organismal Systems; Digestive system; Salivary secretion [PATH:ecb04970]
Organismal Systems; Digestive system; Gastric acid secretion [PATH:ecb04971]
Organismal Systems; Digestive system; Pancreatic secretion [PATH:ecb04972]
Organismal Systems; Excretory system; Endocrine and other factor-regulated calcium reabsorption [PATH:ecb04961]
Organismal Systems; Nervous system; Glutamatergic synapse [PATH:ecb04724]
Organismal Systems; Nervous system; Cholinergic synapse [PATH:ecb04725]
Organismal Systems; Nervous system; Dopaminergic synapse [PATH:ecb04728]
Organismal Systems; Nervous system; Serotonergic synapse [PATH:ecb04726]
Organismal Systems; Nervous system; Long-term potentiation [PATH:ecb04720]
Organismal Systems; Nervous system; Long-term depression [PATH:ecb04730]
Organismal Systems; Nervous system; Retrograde endocannabinoid signaling [PATH:ecb04723]
Organismal Systems; Sensory system; Inflammatory mediator regulation of TRP channels [PATH:ecb04750]
Organismal Systems; Environmental adaptation; Circadian entrainment [PATH:ecb04713]
Human Diseases; Neurodegenerative diseases; Alzheimer's disease [PATH:ecb05010]
Human Diseases; Neurodegenerative diseases; Huntington's disease [PATH:ecb05016]
Human Diseases; Infectious diseases; Amoebiasis [PATH:ecb05146]
Human Diseases; Infectious diseases; Chagas disease (American trypanosomiasis) [PATH:ecb05142]
Human Diseases; Infectious diseases; African trypanosomiasis [PATH:ecb05143]
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
Position
12
AA seq 1188 aa AA seqDB search
MLLQMAGSPPAVPSLQLEPCTVVENLRRGSKFIKWDEEASSRNLVTLRVDANGFFLYWTG
PNMEVDTLDISSIRDTRTGRYARLPKDPKIREVLGFGGPDARLEEKLMTVVAGPDPVNTT
FLNFMAVQDDTAKVWSEELFKLAMNILAQNASRNTFLRKAYTKLKLQVNQDGRIPVKNIL
KMFSADKKRVETALESCGLNFNRSESIRPDEFSLEIFERFLNKLCLRPDIDKILLEIGAK
GKPYLTLEQLMDFINQKQRDPRLNEVLYPPLRHSQARQLIEKYEPNQQFLERDQMSMEGF
SRYLGGEENGILPLEALDLSADMTQPLSAYFINSSHNTYLTAGQLAGTSSVEMYRQALLW
GCRCVELDVWKGRPPEEEPFITHGFTMTTEVPLRDVLEAIAETAFKTSPYPVILSFENHV
DSAKQQAKMAEYCRSIFGDALRTALRGPLPHCVTSTRTGHNPSWLLRSPSSDSCPGLSNG
EEVALEKPSLEPQKSLGEEGPQRGPDALGPVDREDEEEDEEEEEQTDPKKPTTDEGTASS
EVNATEEMSTLVNYIEPVKFKSFEAARKRNKCFEMSSFVETKAMEQLTKSPMEFVEYNKQ
QLSRIYPKGTRVDSSNYMPQLFWNVGCQLVALNFQTLDVAMQLNAGVFEYNGRSGYLLKP
EFMRRPDKSFDPFTEVIVDGIVANALRVKVISGQFLSDRKVGIYVEVDMFGLPVDTRRKY
RTRTSQGNSFNPVWDEEPFDFPKVVLPTLASLRIAAFEEGGKFVGHRILPVSAIRSGYHY
ICLRNEANQPLCLPALLIYTEASDYIPDDHQDYAEALINPIKHVSLMDQRAKQLAALIGE
SEAQAGPETCQETQSQQLGSQLTPNPTPSTLDTSPRRPPGTVTSPTSPSLSSPGQRDDLV
ASILAEVAPAPLDELRGHKALVKLRSRQERDLRELRKKHQRKAVALTRRLLDGLAQARAE
GRCRPRPGGLGGEDEKEEEKEVKHYQEFQKRQVQSLLELREAQADTESKWRLEHLRQAQQ
RLREVVLDAHTTQLKRLKETNDREKKELQKILDRKRHNSISEAKTREKHKKEAELTEINR
RHITESVNSIRRLEEAQKQRQERLVAGQQQVLQQLAEEEPKLLAQLAQECQEQRARLPQE
VRRSLLGETPEGLGDGHLVACASNGHAPGSSGHLSGADSESQEENTKL
NT seq 3567 nt NT seq  +upstreamnt  +downstreamnt
atgcttttgcagatggcaggctcaccgcctgcggtcccaagcctgcagctggagccgtgt
accgtggtggagaacctgcggcgcgggagtaagttcatcaaatgggacgaggaggcctcc
agtcggaacctggtgaccctgcgcgtggacgccaatggcttctttttgtactggacagga
cccaacatggaagtggacacactggacatcagttccatcagggacacgcggacaggccgt
tacgcccgcctgcccaaggaccccaagatccgggaggtgctgggctttgggggccccgat
gcccggctggaggagaagctgatgacggtggtggccgggccagacccggtgaacacgaca
ttcttgaacttcatggccgtgcaggacgacacagccaaggtctggtccgaggagctgttc
aagctggctatgaacatcctggctcagaatgcctcccggaacaccttcttgcgcaaagca
tacacgaagctgaagctgcaggtgaaccaggatgggaggatcccggtgaagaacatcctg
aagatgttctcagcagacaagaagcgggtggaaactgcgctggaatcctgtggcctcaat
ttcaatcggagcgagtccatccggcccgacgagttttccttggaaatcttcgagcggttc
ctgaacaagctgtgtctgcggccggacattgacaagatcctgctggagataggcgccaag
ggcaagccatacctgacgctagagcagctcatggacttcatcaaccagaagcagcgggac
ccgaggctcaacgaggtgctgtacccgcccctgcggcactcccaggcgaggcagctcatc
gagaagtacgaacccaaccagcagttcctggagcgagaccagatgtccatggaaggtttc
agccgctacctgggaggtgaggagaacggcatcctgcccctggaggccctggacctgagc
gccgacatgacgcagccgctcagtgcttacttcatcaactcttcccataacacctacctc
acggcggggcagctggccgggacctcgtcggtggagatgtaccggcaggcgctgctgtgg
ggctgccgctgcgtggagctggacgtgtggaaggggcggccgcccgaggaggagccattc
atcacgcacggcttcaccatgaccaccgaggtgccgctgcgggacgtgctcgaggccatc
gcggagaccgccttcaagacctcgccctaccccgtcatcctctccttcgagaaccacgtg
gactcggcaaagcagcaggccaagatggccgagtactgccgctccatctttggggacgcg
ctccgcactgccctgagaggaccccttccccactgcgtcacctccacacgcactgggcac
aacccctcctggctcctgaggtcccccagctccgacagctgccccggcctgagcaacggg
gaggaggtggccctcgagaagcccagcctggagcctcagaagtctctgggggaggagggg
ccgcagcggggccccgatgctcttggacctgttgaccgcgaggatgaggaggaagacgag
gaagaggaggaacagacggaccccaaaaagcccaccacggatgagggcaccgccagcagc
gaggtcaatgccacagaggaaatgtcgaccctcgtcaactacatcgagcccgtcaagttc
aagtccttcgaggctgcccgaaagaggaacaagtgcttcgagatgtcgtccttcgtggag
accaaggccatggagcagctgaccaagagccccatggagttcgtggaatacaacaagcag
cagctgagccgtatctaccccaagggcacccgcgtggactcgtctaactacatgccccag
ctcttctggaatgtgggctgccagcttgtcgcgctcaacttccagaccctggatgtggcg
atgcagctcaacgcgggcgtgttcgagtacaacgggcgcagcggctacctgcttaaaccc
gagttcatgcggcggccggacaagtcctttgaccccttcaccgaggtcatcgtggatggc
atcgtggccaatgccttgcgggtcaaggtgatctcggggcagttcctgtccgacaggaag
gtgggcatctacgtggaggtggatatgttcggcctccctgtggacacgcggcgcaagtac
cgcacgcggacctctcaggggaactcgttcaaccccgtgtgggatgaggagcccttcgac
ttccccaaggtggtgctgcccacgctggcttcactgcgcatcgcggcttttgaggagggc
ggcaagttcgtggggcaccggatcctgcccgtctctgccatccgctcagggtaccactac
atctgcctgcggaacgaggccaaccagccgctgtgcctgccggccctgctcatctacacc
gaggcctccgactacatccctgacgaccaccaggactacgcagaggccctgatcaacccc
atcaagcatgtcagcctgatggaccagagggccaagcagctggctgccctcattggggag
agcgaggctcaggctggcccggagacatgccaggagacccagtctcagcagctggggtcc
cagctgaccccaaaccccacacccagcacactggacacctccccccgccggcccccaggc
actgtcacctcccccaccagtccgtccctcagcagcccaggccaacgggatgatctcgtc
gccagcatcctcgcagaggtggccccagccccactggacgagctccgaggccacaaggct
ctggtgaagctccggagccggcaggagcgagacctgcgggagctgcgcaagaagcatcag
cggaaggccgtagccctcactcgccgcctgctcgacggcctggcccaggctcgggccgag
ggcaggtgccggccccggccaggtggcctaggcggggaggacgagaaggaggaggagaaa
gaggtgaagcactatcaggagttccagaaaagacaggtgcagagtctgctggagctgagg
gaggcccaggccgacacagagagcaagtggaggctggagcacctgcgacaggctcagcag
cggctcagggaggttgtcctggatgcacacacaacccagttaaagaggctgaaggagacg
aacgacagggagaagaaggaactgcagaagatcctggacaggaagcgccacaacagtatc
tcggaggccaagacaagggagaaacataagaaggaggcggaactgaccgagatcaaccgt
cggcacatcactgagtcggtcaactccatccgtcggctggaggaggcccagaagcagcgg
caggagcgccttgtggccgggcagcagcaggtcctgcagcagctggcagaagaggagccc
aagctgctggcccagctggcccaggagtgtcaggagcagcgggcaaggctgccccaggag
gtccgccggagcctgctgggcgagacgccggaggggctgggggacgggcatctggtggcc
tgtgccagcaacggtcacgcgcccgggagcagcgggcacctgtctggtgctgactcggag
agccaagaggagaatacgaagctctga

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