KEGG   Equus caballus (horse): 100055407Help
Entry
100055407         CDS       T01058                                 

Gene name
PLCB3
Definition
phospholipase C, beta 3 (phosphatidylinositol-specific)
Orthology
K05858  
phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
ecb  Equus caballus (horse)
Pathway
Inositol phosphate metabolism
Metabolic pathways
Rap1 signaling pathway
Calcium signaling pathway
cGMP-PKG signaling pathway
Chemokine signaling pathway
Phosphatidylinositol signaling system
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Wnt signaling pathway
Gap junction
Platelet activation
Circadian entrainment
Long-term potentiation
Retrograde endocannabinoid signaling
Glutamatergic synapse
Cholinergic synapse
Serotonergic synapse
Dopaminergic synapse
Long-term depression
Inflammatory mediator regulation of TRP channels
Insulin secretion
GnRH signaling pathway
Estrogen signaling pathway
Melanogenesis
Thyroid hormone synthesis
Thyroid hormone signaling pathway
Oxytocin signaling pathway
Endocrine and other factor-regulated calcium reabsorption
Salivary secretion
Gastric acid secretion
Pancreatic secretion
Alzheimer's disease
Huntington's disease
Chagas disease (American trypanosomiasis)
African trypanosomiasis
Amoebiasis
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:ecb00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    100055407 (PLCB3)
 Environmental Information Processing
  Signal transduction
   04015 Rap1 signaling pathway
    100055407 (PLCB3)
   04310 Wnt signaling pathway
    100055407 (PLCB3)
   04020 Calcium signaling pathway
    100055407 (PLCB3)
   04070 Phosphatidylinositol signaling system
    100055407 (PLCB3)
   04022 cGMP - PKG signaling pathway
    100055407 (PLCB3)
 Cellular Processes
  Cell communication
   04540 Gap junction
    100055407 (PLCB3)
 Organismal Systems
  Immune system
   04611 Platelet activation
    100055407 (PLCB3)
   04062 Chemokine signaling pathway
    100055407 (PLCB3)
  Endocrine system
   04911 Insulin secretion
    100055407 (PLCB3)
   04912 GnRH signaling pathway
    100055407 (PLCB3)
   04915 Estrogen signaling pathway
    100055407 (PLCB3)
   04921 Oxytocin signaling pathway
    100055407 (PLCB3)
   04918 Thyroid hormone synthesis
    100055407 (PLCB3)
   04919 Thyroid hormone signaling pathway
    100055407 (PLCB3)
   04916 Melanogenesis
    100055407 (PLCB3)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100055407 (PLCB3)
   04270 Vascular smooth muscle contraction
    100055407 (PLCB3)
  Digestive system
   04970 Salivary secretion
    100055407 (PLCB3)
   04971 Gastric acid secretion
    100055407 (PLCB3)
   04972 Pancreatic secretion
    100055407 (PLCB3)
  Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    100055407 (PLCB3)
  Nervous system
   04724 Glutamatergic synapse
    100055407 (PLCB3)
   04725 Cholinergic synapse
    100055407 (PLCB3)
   04728 Dopaminergic synapse
    100055407 (PLCB3)
   04726 Serotonergic synapse
    100055407 (PLCB3)
   04720 Long-term potentiation
    100055407 (PLCB3)
   04730 Long-term depression
    100055407 (PLCB3)
   04723 Retrograde endocannabinoid signaling
    100055407 (PLCB3)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100055407 (PLCB3)
  Environmental adaptation
   04713 Circadian entrainment
    100055407 (PLCB3)
 Human Diseases
  Neurodegenerative diseases
   05010 Alzheimer's disease
    100055407 (PLCB3)
   05016 Huntington's disease
    100055407 (PLCB3)
  Infectious diseases
   05146 Amoebiasis
    100055407 (PLCB3)
   05142 Chagas disease (American trypanosomiasis)
    100055407 (PLCB3)
   05143 African trypanosomiasis
    100055407 (PLCB3)
Enzymes [BR:ecb01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     100055407 (PLCB3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
Position
12
AA seq 1188 aa AA seqDB search
MLLQMAGSPPAVPSLQLEPCTVVENLRRGSKFIKWDEEASSRNLVTLRVDANGFFLYWTG
PNMEVDTLDISSIRDTRTGRYARLPKDPKIREVLGFGGPDARLEEKLMTVVAGPDPVNTT
FLNFMAVQDDTAKVWSEELFKLAMNILAQNASRNTFLRKAYTKLKLQVNQDGRIPVKNIL
KMFSADKKRVETALESCGLNFNRSESIRPDEFSLEIFERFLNKLCLRPDIDKILLEIGAK
GKPYLTLEQLMDFINQKQRDPRLNEVLYPPLRHSQARQLIEKYEPNQQFLERDQMSMEGF
SRYLGGEENGILPLEALDLSADMTQPLSAYFINSSHNTYLTAGQLAGTSSVEMYRQALLW
GCRCVELDVWKGRPPEEEPFITHGFTMTTEVPLRDVLEAIAETAFKTSPYPVILSFENHV
DSAKQQAKMAEYCRSIFGDALRTALRGPLPHCVTSTRTGHNPSWLLRSPSSDSCPGLSNG
EEVALEKPSLEPQKSLGEEGPQRGPDALGPVDREDEEEDEEEEEQTDPKKPTTDEGTASS
EVNATEEMSTLVNYIEPVKFKSFEAARKRNKCFEMSSFVETKAMEQLTKSPMEFVEYNKQ
QLSRIYPKGTRVDSSNYMPQLFWNVGCQLVALNFQTLDVAMQLNAGVFEYNGRSGYLLKP
EFMRRPDKSFDPFTEVIVDGIVANALRVKVISGQFLSDRKVGIYVEVDMFGLPVDTRRKY
RTRTSQGNSFNPVWDEEPFDFPKVVLPTLASLRIAAFEEGGKFVGHRILPVSAIRSGYHY
ICLRNEANQPLCLPALLIYTEASDYIPDDHQDYAEALINPIKHVSLMDQRAKQLAALIGE
SEAQAGPETCQETQSQQLGSQLTPNPTPSTLDTSPRRPPGTVTSPTSPSLSSPGQRDDLV
ASILAEVAPAPLDELRGHKALVKLRSRQERDLRELRKKHQRKAVALTRRLLDGLAQARAE
GRCRPRPGGLGGEDEKEEEKEVKHYQEFQKRQVQSLLELREAQADTESKWRLEHLRQAQQ
RLREVVLDAHTTQLKRLKETNDREKKELQKILDRKRHNSISEAKTREKHKKEAELTEINR
RHITESVNSIRRLEEAQKQRQERLVAGQQQVLQQLAEEEPKLLAQLAQECQEQRARLPQE
VRRSLLGETPEGLGDGHLVACASNGHAPGSSGHLSGADSESQEENTKL
NT seq 3567 nt NT seq  +upstreamnt  +downstreamnt
atgcttttgcagatggcaggctcaccgcctgcggtcccaagcctgcagctggagccgtgt
accgtggtggagaacctgcggcgcgggagtaagttcatcaaatgggacgaggaggcctcc
agtcggaacctggtgaccctgcgcgtggacgccaatggcttctttttgtactggacagga
cccaacatggaagtggacacactggacatcagttccatcagggacacgcggacaggccgt
tacgcccgcctgcccaaggaccccaagatccgggaggtgctgggctttgggggccccgat
gcccggctggaggagaagctgatgacggtggtggccgggccagacccggtgaacacgaca
ttcttgaacttcatggccgtgcaggacgacacagccaaggtctggtccgaggagctgttc
aagctggctatgaacatcctggctcagaatgcctcccggaacaccttcttgcgcaaagca
tacacgaagctgaagctgcaggtgaaccaggatgggaggatcccggtgaagaacatcctg
aagatgttctcagcagacaagaagcgggtggaaactgcgctggaatcctgtggcctcaat
ttcaatcggagcgagtccatccggcccgacgagttttccttggaaatcttcgagcggttc
ctgaacaagctgtgtctgcggccggacattgacaagatcctgctggagataggcgccaag
ggcaagccatacctgacgctagagcagctcatggacttcatcaaccagaagcagcgggac
ccgaggctcaacgaggtgctgtacccgcccctgcggcactcccaggcgaggcagctcatc
gagaagtacgaacccaaccagcagttcctggagcgagaccagatgtccatggaaggtttc
agccgctacctgggaggtgaggagaacggcatcctgcccctggaggccctggacctgagc
gccgacatgacgcagccgctcagtgcttacttcatcaactcttcccataacacctacctc
acggcggggcagctggccgggacctcgtcggtggagatgtaccggcaggcgctgctgtgg
ggctgccgctgcgtggagctggacgtgtggaaggggcggccgcccgaggaggagccattc
atcacgcacggcttcaccatgaccaccgaggtgccgctgcgggacgtgctcgaggccatc
gcggagaccgccttcaagacctcgccctaccccgtcatcctctccttcgagaaccacgtg
gactcggcaaagcagcaggccaagatggccgagtactgccgctccatctttggggacgcg
ctccgcactgccctgagaggaccccttccccactgcgtcacctccacacgcactgggcac
aacccctcctggctcctgaggtcccccagctccgacagctgccccggcctgagcaacggg
gaggaggtggccctcgagaagcccagcctggagcctcagaagtctctgggggaggagggg
ccgcagcggggccccgatgctcttggacctgttgaccgcgaggatgaggaggaagacgag
gaagaggaggaacagacggaccccaaaaagcccaccacggatgagggcaccgccagcagc
gaggtcaatgccacagaggaaatgtcgaccctcgtcaactacatcgagcccgtcaagttc
aagtccttcgaggctgcccgaaagaggaacaagtgcttcgagatgtcgtccttcgtggag
accaaggccatggagcagctgaccaagagccccatggagttcgtggaatacaacaagcag
cagctgagccgtatctaccccaagggcacccgcgtggactcgtctaactacatgccccag
ctcttctggaatgtgggctgccagcttgtcgcgctcaacttccagaccctggatgtggcg
atgcagctcaacgcgggcgtgttcgagtacaacgggcgcagcggctacctgcttaaaccc
gagttcatgcggcggccggacaagtcctttgaccccttcaccgaggtcatcgtggatggc
atcgtggccaatgccttgcgggtcaaggtgatctcggggcagttcctgtccgacaggaag
gtgggcatctacgtggaggtggatatgttcggcctccctgtggacacgcggcgcaagtac
cgcacgcggacctctcaggggaactcgttcaaccccgtgtgggatgaggagcccttcgac
ttccccaaggtggtgctgcccacgctggcttcactgcgcatcgcggcttttgaggagggc
ggcaagttcgtggggcaccggatcctgcccgtctctgccatccgctcagggtaccactac
atctgcctgcggaacgaggccaaccagccgctgtgcctgccggccctgctcatctacacc
gaggcctccgactacatccctgacgaccaccaggactacgcagaggccctgatcaacccc
atcaagcatgtcagcctgatggaccagagggccaagcagctggctgccctcattggggag
agcgaggctcaggctggcccggagacatgccaggagacccagtctcagcagctggggtcc
cagctgaccccaaaccccacacccagcacactggacacctccccccgccggcccccaggc
actgtcacctcccccaccagtccgtccctcagcagcccaggccaacgggatgatctcgtc
gccagcatcctcgcagaggtggccccagccccactggacgagctccgaggccacaaggct
ctggtgaagctccggagccggcaggagcgagacctgcgggagctgcgcaagaagcatcag
cggaaggccgtagccctcactcgccgcctgctcgacggcctggcccaggctcgggccgag
ggcaggtgccggccccggccaggtggcctaggcggggaggacgagaaggaggaggagaaa
gaggtgaagcactatcaggagttccagaaaagacaggtgcagagtctgctggagctgagg
gaggcccaggccgacacagagagcaagtggaggctggagcacctgcgacaggctcagcag
cggctcagggaggttgtcctggatgcacacacaacccagttaaagaggctgaaggagacg
aacgacagggagaagaaggaactgcagaagatcctggacaggaagcgccacaacagtatc
tcggaggccaagacaagggagaaacataagaaggaggcggaactgaccgagatcaaccgt
cggcacatcactgagtcggtcaactccatccgtcggctggaggaggcccagaagcagcgg
caggagcgccttgtggccgggcagcagcaggtcctgcagcagctggcagaagaggagccc
aagctgctggcccagctggcccaggagtgtcaggagcagcgggcaaggctgccccaggag
gtccgccggagcctgctgggcgagacgccggaggggctgggggacgggcatctggtggcc
tgtgccagcaacggtcacgcgcccgggagcagcgggcacctgtctggtgctgactcggag
agccaagaggagaatacgaagctctga

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