KEGG   Equus caballus (horse): 100059197Help
Entry
100059197         CDS       T01058                                 

Gene name
CACNA2D3
Definition
calcium channel, voltage-dependent, alpha 2/delta subunit 3
Orthology
K04860  
voltage-dependent calcium channel alpha-2/delta-3
Organism
ecb  Equus caballus (horse)
Pathway
MAPK signaling pathway
Cardiac muscle contraction
Adrenergic signaling in cardiomyocytes
Oxytocin signaling pathway
Hypertrophic cardiomyopathy (HCM)
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ecb00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    100059197 (CACNA2D3)
 Organismal Systems
  Endocrine system
   04921 Oxytocin signaling pathway
    100059197 (CACNA2D3)
  Circulatory system
   04260 Cardiac muscle contraction
    100059197 (CACNA2D3)
   04261 Adrenergic signaling in cardiomyocytes
    100059197 (CACNA2D3)
 Human Diseases
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    100059197 (CACNA2D3)
   05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
    100059197 (CACNA2D3)
   05414 Dilated cardiomyopathy (DCM)
    100059197 (CACNA2D3)
Ion channels [BR:ecb04040]
 Voltage-gated cation channels
  Ca2+ channel, CACN alpha-2 delta
   100059197 (CACNA2D3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
Position
16
AA seq 1056 aa AA seqDB search
MCACAVKLWASAFGGEIKSIAAKYSGSQLLQKKYKEYEKDVAIEEIDGLQLVKKLAKNME
EMFHKKSEAVRRLVEAAEEAHLKHEFDADLQYEYFNAVLINERDKDGNFLELGKEFILAP
NDHFNNLPVNISLSDVQVPTNMYNKDPAIVNGVYWSESLNKVFVDNFDRDPSLIWQYFGS
AKGFFRQYPGIKWEPDENGVIAFDCRNRKWYIQAATSPKDVVILVDVSGSMKGLRLTIAK
QTVSSILDTLGDDDFFNIIAYNEELHYVEPCLNGTLVQADRTNKEHFREHLDKLFAKGIG
MLDIALNEAFNILSDFNHTGQGSICIQAIMLITDGAVDTYDTIFAKYNWPDRKVRIFTYL
IGREAAFADNLKWMACANKGFFTQISTLADVQENVMEYLHVLSRPKVIDQEHDVVWTEAY
IDSTLPQAQKLADDQGLVLMTTVAMPVFSKQNETRSKGILLGVVGTDVPVKELLKTIPKY
KLGIHGYAFAITNNGYILTHPELRPLYEEGKKRRKPNYSSVDLSEVEWEDRDDVLRNAMV
NRKTGKFSMEVKKTVDKGKRVLVMTNDYYYTDIKGTPFSLGVALSRGHGKYFFRGNVTIE
EGLHDLEHPDVSLADEWSYCNTDLHPEHRHLSQLEAIKLYLKGKEPLLQCDKELIQEVLF
DAVVSAPIEAYWTSLALNKSENSDKGVEVAFLGTRTGLSRINLFVGAEQLTNQDFLKAGD
KENIFNADHFPLWYRRAAEQIPGSFVYSIPFSTGTVNKSNVVTASTSIQLLDERKSPVVA
AVGIQMKLEFFQRKFWTASRQCASLDGKCSISCDDETVNCYLIDNNGFILVSEDYTQTGD
FFGEVEGAVMNKLLTMGSFKRITLYDYQAMCRANKESSDGAYGLLDPYNAFLAAVKWIMT
ELVLFLVEFNLCSWWHSDITAKAQKLKQTLEPCDTEYPAFVSERTIKETSGNIACEDCSK
SFVIQQIPSSNLFMVVVDSSCLCESIAPITMAPIEISQHNESLKCERLKAQKIRRRPESC
HGFHPEENARECGGAPGIQAKMVLILFPLLLMLFSR
NT seq 3171 nt NT seq  +upstreamnt  +downstreamnt
atgtgtgcgtgtgcggtgaagctctgggcctcggcttttggtggggagataaaatccatt
gctgctaagtactccggctcccagcttctgcaaaagaaatacaaagaatatgagaaagat
gttgccatagaagaaatcgatggtctccaactggtgaaaaagctggcaaagaacatggaa
gagatgtttcacaaaaagtcggaagcagtgaggcgtcttgtggaggctgcagaagaagca
cacctgaaacatgaatttgatgcagacttgcagtatgaatacttcaatgccgtgctgata
aacgaaagggacaaagatgggaattttttggagctggggaaggaattcatcttagcccca
aatgaccattttaataatttgcctgtgaacatcagtctgagtgacgtccaagtgccaacg
aacatgtacaacaaagacccagcaattgtcaatggggtttattggtccgaatctctaaac
aaagtctttgtagataattttgaccgtgacccgtctctcatctggcagtactttggaagt
gcaaagggcttttttaggcagtatccagggattaaatgggaaccagatgagaatggagtc
attgcctttgactgcaggaaccgaaaatggtacatccaggcagcaacttctccgaaagac
gtggtcattttagttgacgtcagtggcagcatgaaagggctccgtctgacgattgcaaag
caaacggtctcatctattttggatacgctgggggatgacgacttcttcaacataattgct
tataacgaggagcttcactatgtggaaccttgcctgaatggaacgttggtgcaagccgac
aggacaaacaaggagcatttcagggagcatctggacaaactttttgccaaaggaatcgga
atgctggatatagctctgaatgaggccttcaacattctcagtgatttcaaccacacagga
caaggaagcatctgcatccaggccatcatgctcattaccgatggggcagtggacacctat
gatactatctttgcgaaatacaattggccagatcgaaaggttcgcatcttcacgtacctc
attggacgagaggctgcttttgcagacaatctcaagtggatggcctgtgccaacaaagga
tttttcacccagatctccaccttggctgatgtgcaggaaaatgtcatggaatacctccac
gtgctcagccggcccaaagtcattgaccaagagcacgacgtggtgtggacagaagcttac
attgacagcactctccctcaggcacaaaagcttgctgatgatcagggccttgtcctcatg
accacggtcgccatgcccgtgtttagtaagcagaatgaaaccagatcaaaaggcattctt
ctgggcgtggttggcacagatgtcccagtgaaagaacttctgaagaccattcccaaatac
aagttagggattcacggttatgcctttgcaatcacaaataatggatatatcctgacgcat
ccagaactcagaccactgtacgaagaaggaaaaaagcgaaggaaacccaactatagcagc
gttgacctctctgaggtggagtgggaagaccgagatgacgtgttgagaaatgccatggtg
aatcgaaagactgggaagttttccatggaggtgaagaagacagtggacaaagggaaacgg
gttttggtgatgacaaatgactactattatacagacatcaagggtactcctttcagttta
ggtgtggcgctctccagaggccatgggaaatatttcttccgagggaatgtaaccattgaa
gaaggcctacatgacttagagcatcctgatgtgtccttggcagacgaatggtcctactgc
aacactgacctacacccagagcaccgtcatctgtctcagttagaagctattaagctctac
ctcaaaggcaaagaacctctgctgcagtgtgataaagaattgatacaggaagtccttttc
gatgccgtagtgagtgcccccatcgaagcatactggaccagccttgccctcaacaaatct
gagaattctgacaagggcgtagaggttgccttcctcggcactcgcacgggcctctcgaga
atcaacctgtttgttggggctgagcagctcaccaatcaggactttctgaaagctggagac
aaggagaacatttttaatgcagaccatttccctctctggtaccgaagagccgctgagcag
attccaggaagcttcgtctattcgattccgttcagcacaggaacagtcaacaaaagcaat
gtggtgacagcgagtacctccatacagctcctggatgagcggaaatctcctgtggtggca
gctgtaggcattcagatgaaacttgaatttttccaaaggaagttctggactgccagcaga
cagtgcgcctctctggatggcaaatgctccatcagctgcgatgacgagactgtgaactgt
tacctcatagacaataatggatttattctggtatcggaagactacacacagactggagac
ttttttggtgaggtcgagggagctgtgatgaacaaattgttaacaatgggctcctttaaa
aggattaccctttatgactatcaagccatgtgcagggccaacaaggagagcagcgatggt
gcctatggtctgctggatccttataatgccttccttgctgcagtaaaatggataatgaca
gaacttgtcttgttcctggtggaatttaacctctgcagttggtggcactcagatataaca
gctaaagcccagaaattgaagcagaccttggagccttgtgatactgaatatccagcgttt
gtctctgagcgcaccatcaaggaaacctcagggaacattgcttgcgaagactgctccaag
tcctttgtcatccagcaaatcccaagcagcaatctgttcatggtggtggtggacagcagc
tgcctctgtgagtccatagcccccatcaccatggcgcccattgaaatcagtcaacataac
gaatcccttaagtgtgaacgcttaaaggcccagaagatcagaaggcgtccggagtcttgt
catggcttccatcctgaggaaaacgcaagagagtgtggaggtgcaccgggcatccaagcc
aagatggtccttatcctgttccctctgcttttgatgctcttctcaaggtga

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