KEGG   Equus caballus (horse): 100059233Help
Entry
100059233         CDS       T01058                                 

Gene name
PPP1CA
Definition
protein phosphatase 1, catalytic subunit, alpha isozyme
Orthology
K06269  
serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
Organism
ecb  Equus caballus (horse)
Pathway
mRNA surveillance pathway
cGMP-PKG signaling pathway
cAMP signaling pathway
Oocyte meiosis
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Hippo signaling pathway
Focal adhesion
Platelet activation
Long-term potentiation
Dopaminergic synapse
Inflammatory mediator regulation of TRP channels
Regulation of actin cytoskeleton
Insulin signaling pathway
Oxytocin signaling pathway
Amphetamine addiction
Alcoholism
Herpes simplex infection
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:ecb00001]
 Genetic Information Processing
  Translation
   03015 mRNA surveillance pathway
    100059233 (PPP1CA)
 Environmental Information Processing
  Signal transduction
   04390 Hippo signaling pathway
    100059233 (PPP1CA)
   04024 cAMP signaling pathway
    100059233 (PPP1CA)
   04022 cGMP - PKG signaling pathway
    100059233 (PPP1CA)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    100059233 (PPP1CA)
  Cell growth and death
   04114 Oocyte meiosis
    100059233 (PPP1CA)
  Cellular commiunity
   04510 Focal adhesion
    100059233 (PPP1CA)
 Organismal Systems
  Immune system
   04611 Platelet activation
    100059233 (PPP1CA)
  Endocrine system
   04910 Insulin signaling pathway
    100059233 (PPP1CA)
   04921 Oxytocin signaling pathway
    100059233 (PPP1CA)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100059233 (PPP1CA)
   04270 Vascular smooth muscle contraction
    100059233 (PPP1CA)
  Nervous system
   04728 Dopaminergic synapse
    100059233 (PPP1CA)
   04720 Long-term potentiation
    100059233 (PPP1CA)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100059233 (PPP1CA)
 Human Diseases
  Cancers
   05205 Proteoglycans in cancer
    100059233 (PPP1CA)
  Substance dependence
   05031 Amphetamine addiction
    100059233 (PPP1CA)
   05034 Alcoholism
    100059233 (PPP1CA)
  Infectious diseases
   05168 Herpes simplex infection
    100059233 (PPP1CA)
Enzymes [BR:ecb01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     100059233 (PPP1CA)
Protein phosphatases and associated proteins [BR:ecb01009]
 Protein Ser/ Thr phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    Catalytic subunits
     100059233 (PPP1CA)
Transcription machinery [BR:ecb03021]
 Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Transcription termination factor
     100059233 (PPP1CA)
Spliceosome [BR:ecb03041]
 Other splicing related proteins
  Spliceosome associated proteins (SAPs)
   Other SAPs
    100059233 (PPP1CA)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
Position
12
AA seq 356 aa AA seqDB search
MREQPEKPSPPHPTPGKGSCYGVSVAVPSKCLEGTRVLTSHSAPVQGSRPGKNVQLTENE
IRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYV
DRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTD
CFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVQ
GWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCG
EFDNAGAMMSVDETLMCSFQILKPADKNKGKYGQFSGLNPGGRPITPPRNSAKAKK
NT seq 1071 nt NT seq  +upstreamnt  +downstreamnt
atgagggagcagcctgagaaacctagccccccccaccccacccccgggaaggggtcctgc
tatggggtttcggtggcagtcccctcaaagtgcctggaggggacgagggtcctgacgtcc
cattccgccccagtgcagggctcacggcctggaaagaatgtacagctgacagagaacgag
atccgtggtctgtgcctcaaatcccgggagatcttcctgagccagccaattcttctggag
ctggaggcgcccctcaagatctgtggtgacatccatggccagtactacgatcttctgcgg
ctgttcgagtatggtggcttccctccagagagcaactacctcttcctgggggactacgtg
gaccggggcaagcagtctttggagaccatctgcctgctgctggcctataagatcaagtac
cccgagaacttcttcctgctccgcgggaaccatgagtgtgccagcatcaaccgcatctac
ggtttctatgatgagtgcaagagacgctacaacattaaactgtggaaaaccttcaccgac
tgcttcaactgcctgcccatcgctgccatcgtggacgagaagatcttctgctgccacgga
gggctgtcgcccgacctgcagtccatggaacagattcggcgtatcatgcggcccacagac
gtgcctgaccaggggctgctgtgtgacctgctgtggtccgacccggacaaggacgtgcag
ggctggggcgagaacgaccgtggggtctcctttactttcggggctgaggtggtggccaag
ttcctgcacaagcacgatttggacctcatctgccgggcgcaccaggtggtggaagatggc
tatgagttctttgccaagcggcagctggtgacactcttctcagctcccaactactgtggc
gagtttgacaacgcaggtgccatgatgagcgtggacgagacgctcatgtgctccttccag
atcctcaagcccgcggacaagaacaaggggaaatacgggcagttcagtggcctgaaccct
ggaggccggcccatcaccccaccccgcaactccgccaaagccaagaaatag

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