KEGG   Equus caballus (horse): 100059815Help
Entry
100059815         CDS       T01058                                 

Gene name
PDGFRA
Definition
platelet-derived growth factor receptor, alpha polypeptide
Orthology
K04363  
platelet-derived growth factor receptor alpha [EC:2.7.10.1]
Organism
ecb  Equus caballus (horse)
Pathway
MAPK signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Calcium signaling pathway
Cytokine-cytokine receptor interaction
Endocytosis
PI3K-Akt signaling pathway
Focal adhesion
Gap junction
Regulation of actin cytoskeleton
HTLV-I infection
Pathways in cancer
MicroRNAs in cancer
Glioma
Prostate cancer
Melanoma
Central carbon metabolism in cancer
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:ecb00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    100059815 (PDGFRA)
   04015 Rap1 signaling pathway
    100059815 (PDGFRA)
   04010 MAPK signaling pathway
    100059815 (PDGFRA)
   04020 Calcium signaling pathway
    100059815 (PDGFRA)
   04151 PI3K-Akt signaling pathway
    100059815 (PDGFRA)
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100059815 (PDGFRA)
 Cellular Processes
  Transport and catabolism
   04144 Endocytosis
    100059815 (PDGFRA)
  Cell motility
   04810 Regulation of actin cytoskeleton
    100059815 (PDGFRA)
  Cellular commiunity
   04510 Focal adhesion
    100059815 (PDGFRA)
   04540 Gap junction
    100059815 (PDGFRA)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100059815 (PDGFRA)
   05230 Central carbon metabolism in cancer
    100059815 (PDGFRA)
   05231 Choline metabolism in cancer
    100059815 (PDGFRA)
   05206 MicroRNAs in cancer
    100059815 (PDGFRA)
   05214 Glioma
    100059815 (PDGFRA)
   05218 Melanoma
    100059815 (PDGFRA)
   05215 Prostate cancer
    100059815 (PDGFRA)
  Infectious diseases
   05166 HTLV-I infection
    100059815 (PDGFRA)
Enzymes [BR:ecb01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     100059815 (PDGFRA)
Protein kinases [BR:ecb01001]
 Tyrosine protein kinases
  PDGFR family [OT]
   100059815 (PDGFRA)
Enzyme-linked receptors [BR:ecb01020]
 Receptor tyrosine kinases
  RTK class III (PDGF receptor family)
   100059815 (PDGFRA)
Cytokine receptors [BR:ecb04050]
 Receptor tyrosine kinase
  RTK class III (PDGF receptor family)
   100059815 (PDGFRA)
Cellular antigens [BR:ecb04090]
 Proteins
  100059815 (PDGFRA)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
UniProt: 
Position
3
AA seq 1089 aa AA seqDB search
MGTCHRALLVLGCLLTGPSLSFCQLSLPSILPNEDEKVVQLNSSFSLRCFGESEVSWQYP
MSEEENPNVEIRNEENNSGLFVTVLEVVSASAAHTGLYTCYYNHTQTEESEIEGRRIYIY
VPDPDVAFVPLGMTDYLVIVEDDDSAIIPCRTTDPETPVTLLSSDGVVLASYDSRQGFNG
TFSVGPYICEATVKGKKFRTIPFNVYALKATSELDLEMEALKTVYKSGETIVVTCAVFNN
EVVDLQWTYPGEVKGKGITMLEEIKVPSIKLVYTLSVPEATVKDSGDYECAARQATREVK
EMKKVTISVHEKGFIEIKPNFSRLEAVDLHEVKHFVVDVQAYPPPRISWLKDNLTLIENL
TEITTDIEKIQEIRYRSKLKLIRAKEEDSGHYTIVVQNEDDVKSYTFELLTQVPSSILDL
VDDHHGSTGGQTVRCTAEGTPLPDIEWMICKDIKKCNNETSWTILANNISNIITEVHPRD
RSTVEGRVTFAKVEETIAVRCLAKNLLGAENRELKLVAPTLRSELTVAAAVLVLLVIVII
SLIVLVVIWKQKPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRILG
SGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLNIVNL
LGACTKSGPIYIITEYCFYGDLVNYLHKNRDSFLSRHPEKPKKELDIFGLTPADESTRSY
VILSFENNGDYMDMKQADTTQYVPMLERKEVSKYSDIQRSLYDRPASYKKKAMLDSEVKN
LLSDDNSEGLTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLA
RDIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMM
VDSTFYNKIKSGYRMAKPDHATSEVYEIMVKCWNSEPEKRPSFYHLSEIVENLLPGQYKK
SYEKIHLDFLKSDHPAVARMRVDSDNAYIGVTYKNEEDKLKDWEGGLDEQRLSADSGYII
PLPDIDPVPEEEDLGKRNRHSSQTSEESAIETGSSSSTFIKREDETIEDIDMMDDIGIDS
SDLVEDSFL
NT seq 3270 nt NT seq  +upstreamnt  +downstreamnt
atggggacttgccatcgggcactcctggtcttaggctgtctcctcacagggcccagccta
agcttctgccagctttcattaccctccatcctcccaaatgaagatgaaaaggttgtgcag
ctgaactcatccttttctctgagatgctttggggagagcgaagtgagctggcagtacccc
atgtctgaagaagagaaccctaacgtggaaatcagaaatgaggaaaacaacagtggcctt
tttgtgacggtgctggaagtggtcagtgcctcagcagcccacacgggattgtacacttgc
tattacaaccacacgcagacagaagaaagcgagatcgaaggcaggcgcatttacatctat
gtgccagaccctgatgtggccttcgtacctctaggaatgacagactatttagtcatcgtg
gaggatgatgattctgccatcatcccttgtcgcacgactgatcctgagactccagtgacc
ttactcagcagtgacggggtggtactcgcctcctacgacagcagacagggctttaacgga
accttcagcgtcgggccctacatctgcgaggccaccgtcaaagggaagaagtttcggacc
atcccatttaatgtttatgctttaaaagcaacatcagaacttgatctagagatggaagct
cttaagactgtgtataagtcgggggaaacgattgtggtcacctgtgccgtctttaacaac
gaggtggttgaccttcagtggacttaccctggagaagtgaaaggcaaaggcatcacaatg
ctggaggaaatcaaggtcccgtccatcaaattggtgtacaccctgagcgtccccgaggcc
acggtgaaagacagtggagattacgaatgtgctgcccgccaggccaccagggaggtcaaa
gaaatgaagaaagtcaccatttctgtccatgagaaaggcttcattgaaatcaaacccaac
ttcagccggctggaagccgttgacctgcatgaggtcaaacattttgtggtggatgtgcag
gcctacccgcctcctaggatatcctggctgaaggacaacctgactctgatcgaaaatctc
actgagatcaccactgacatagaaaagatccaggaaataaggtaccgaagcaaattaaag
ctgatccgtgcaaaggaagaagacagtggtcattatactattgtagttcaaaatgaagat
gatgtaaagagctatacctttgaactcttaactcaagttccctcatctattctggacttg
gtcgacgaccaccatggctctaccgggggtcagactgtgagatgcacagctgaagggacc
cctcttcctgacattgagtggatgatttgcaaggatattaagaaatgtaataatgaaact
tcgtggacgattttggctaacaacatctcaaacatcatcacggaggtccacccccgagac
aggagtactgtggagggccgagtgacgtttgccaaagtggaggagaccattgccgttcgg
tgtctggctaagaatctccttggggctgagaaccgagagctgaagctggtggctcccact
ctacgttctgaactcacagtggcagctgcggtcctggtgctgttggtgattgtgatcatc
tcacttattgtcctggttgtcatttggaagcagaaaccgaggtacgaaattcgttggagg
gtcattgaatcaatcagccctgatggacatgaatatatttatgtggacccgatgcagctg
ccttatgactcgagatgggagtttccaagagatggcctcgtgcttggtcgtatcctggga
tctggtgcgtttgggaaagtggtcgaaggaactgcttatggattaagccggtcccaacct
gtcatgaaagtagctgtgaagatgctaaaacccacagccagatctagtgaaaaacaagct
ctcatgtcggaactgaagataatgactcacctggggccgcatttaaacattgtgaacttg
ctgggagcctgtaccaagtcaggcccaatttacatcatcacagagtactgcttctatggg
gatttggtcaactatttgcataagaatagggacagcttcctgagccgccacccagagaag
ccaaagaaagagctggacatctttggattgacccctgctgatgaaagcacacggagttat
gttattttatcttttgaaaacaatggtgactacatggacatgaagcaagctgataccaca
cagtatgtccccatgctggagaggaaagaggtttctaaatattcggacatccagaggtcg
ctgtatgatcgcccagcctcatataagaagaaagctatgttagactcagaagtcaaaaac
ctcctttcggatgataactcagaaggcctaactttgctggatttgttgagcttcacttat
caagttgcccgaggaatggagtttttggcttcaaagaattgtgtccaccgggacctggct
gctcgcaacgtcctcctggcacaagggaaaattgtgaagatctgtgactttggcctggcc
agagacatcatgcatgattccaactacgtgtccaaaggcagcacctttctccctgtgaag
tggatggctcctgagagcatcttcgacaacctctacaccacgctgagtgacgtctggtct
tacggcattctgctctgggagatcttttctcttggtggcacaccctaccctggcatgatg
gtggattctactttctacaataagatcaagagtgggtaccggatggccaagcctgaccat
gccaccagtgaagtctatgagatcatggtgaagtgctggaacagtgagccggagaagagg
ccctccttttaccacctgagtgagattgtggagaatctgctgcctggacaatataaaaag
agttatgaaaagattcacctggacttcctgaagagcgatcatcccgccgtggcacgcatg
cgcgtggactctgacaacgcctacattggcgtcacctacaaaaatgaggaagacaagctg
aaggactgggagggtggcctcgacgagcagaggttgagtgcggacagtggctacatcatc
cctctgccggacatcgaccctgttccggaggaggaagacctgggcaagaggaacagacac
agctcgcagacctctgaagagagtgccatcgagacaggttccagcagttctaccttcatt
aagagagaggatgagaccattgaggacatcgacatgatggacgacattggcatagactcc
tcagacctggtggaggacagcttcctgtaa

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