KEGG T01058: 100060183

Equus caballus (horse): 100060183

Entry

100060183 CDS T01058

Definition

serine/threonine-protein kinase PAK 2-like

Orthology

K04410

p21-activated kinase 2 [EC:2.7.11.1]

Organism

ecb Equus caballus (horse)

Pathway

ecb04010	MAPK signaling pathway
ecb04012	ErbB signaling pathway
ecb04360	Axon guidance
ecb04510	Focal adhesion
ecb04660	T cell receptor signaling pathway
ecb04810	Regulation of actin cytoskeleton
ecb05211	Renal cell carcinoma

Class

Environmental Information Processing; Signal transduction; MAPK signaling pathway [PATH:ecb04010]
Environmental Information Processing; Signal transduction; ErbB signaling pathway [PATH:ecb04012]
Cellular Processes; Cell motility; Regulation of actin cytoskeleton [PATH:ecb04810]
Cellular Processes; Cell communication; Focal adhesion [PATH:ecb04510]
Organismal Systems; Immune system; T cell receptor signaling pathway [PATH:ecb04660]
Organismal Systems; Development; Axon guidance [PATH:ecb04360]
Human Diseases; Cancers; Renal cell carcinoma [PATH:ecb05211]

SSDB

Motif

Pfam:

Pkinase Pkinase_Tyr PBD Kinase-like APH Kdo

Other DBs

NCBI-GI:

149731245

NCBI-GeneID:

100060183

UniProt:

F6W0E0

Position

AA seq 524 aa
MSDNGELEDKPPAPPVRMSSTIFSTASKDPLSANHSLKPLPSVPEEKKPRNKIISIFSGT
EKGSKKKEKERPEISPPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKLEQKKNP
QAVLDVLKFYDSNTVKQKYLSFTPPEKDGFPSGTPALNTKGSETPAVVTEEDDDDEEAAP
PVIAPRPDHTKSIYTRSVIDPIPAPVGESSVDGGPKSSDKQKKKTKMTDEEIMEKLRTIV
SIGDPKKKYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEILVMKE
LKNPNIVNFLDSYLMGDELFVVMEYLAGGSLTDVVTETCMDEAQIAAVCRECLQALEFLH
ANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAY
GPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRC
LEMDVEKRGSAKELLQHPFLKLAKPLSSLTPLIMAAKEAMKSNR

NT seq 1575 nt +upstreamnt +downstreamnt
atgtctgataacggagaactggaagacaagcctccggcgcctcccgtgcgaatgagcagc
accatttttagcactgcaagcaaagatcctttgtcagctaatcacagtttgaaacctttg
ccctctgttccagaggagaaaaagcccaggaataaaatcatctctatcttctcaggcaca
gaaaaaggaagtaagaagaaagagaaggaacggccagaaatttctcctccatctgatttt
gagcacactatccatgttggctttgatgctgttactggagaattcacaggcatgccagaa
cagtgggctcgattattacagacctccaatatcaccaaactagagcaaaagaagaatcct
caggctgtgctggatgtcttaaagttctatgactccaacacagtgaaacagaaatacctg
agctttactcctcctgagaaggatggcttcccttctggaacaccagcactgaataccaag
ggatcagagacaccagcagtagtaacagaggaggacgatgatgatgaagaggctgctccc
cctgttattgccccacgaccggatcatacaaaatcaatttatacacggtctgtaatagac
cctattcctgcaccagttggtgaatctagtgttgatggtggtcctaagtcttctgacaaa
cagaaaaagaagaccaaaatgacagatgaagagattatggagaaattaagaactatcgtg
agcataggtgaccctaagaaaaaatatacaagatatgagaaaattgggcaaggggcttct
ggtacagttttcactgctaccgatgtggcattggggcaggaggttgctatcaaacaaatt
aatttacagaaacagccaaagaaggaattgatcattaatgagattctggtaatgaaagaa
ttaaagaatcccaacatagttaacttcttggacagttacctgatgggagatgaattgttt
gtggtgatggaataccttgctgggggatcgcttactgatgttgtaacagaaacctgcatg
gacgaagcacagatcgctgccgtatgcagagagtgtttacaggcattggagtttttacat
gctaatcaagtgatccacagagacataaaaagtgacaatgtgctattggggatggaagga
tcagttaaacttactgactttggtttctgcgcccagatcacccctgagcagagcaagcga
agtaccatggttggaacgccatactggatggcaccagaggtggtcacacggaaggcttat
ggccctaaagtggacatatggtctctgggtatcatggctattgagatggtggaaggagag
cctccttacctcaacgaaaatcccttgagggcattgtatctgatagcaactaatggaacc
ccagaacttcagaatccagagaagctttctccaatatttcgggatttcttaaatcgatgt
ttggagatggatgtggagaaaagaggttcagccaaagaattgttacagcatcccttcctg
aaactggccaaaccattgtctagcttgacgccgctgatcatggcagccaaagaagcgatg
aagagtaaccgttag

All links

Pathway (7)   
   KEGG PATHWAY (7)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (6)   
   Pfam (6)   
All databases (22)   

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