KEGG   Equus caballus (horse): 100060183Help
Entry
100060183         CDS       T01058                                 

Gene name
PAK2
Definition
p21 protein (Cdc42/Rac)-activated kinase 2
Orthology
K04410  
p21-activated kinase 2 [EC:2.7.11.1]
Organism
ecb  Equus caballus (horse)
Pathway
MAPK signaling pathway
ErbB signaling pathway
Ras signaling pathway
Axon guidance
Focal adhesion
T cell receptor signaling pathway
Regulation of actin cytoskeleton
Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:ecb00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    100060183 (PAK2)
   04010 MAPK signaling pathway
    100060183 (PAK2)
   04012 ErbB signaling pathway
    100060183 (PAK2)
 Cellular Processes
  Cell motility
   04810 Regulation of actin cytoskeleton
    100060183 (PAK2)
  Cell communication
   04510 Focal adhesion
    100060183 (PAK2)
 Organismal Systems
  Immune system
   04660 T cell receptor signaling pathway
    100060183 (PAK2)
  Development
   04360 Axon guidance
    100060183 (PAK2)
 Human Diseases
  Cancers
   05211 Renal cell carcinoma
    100060183 (PAK2)
Enzymes [BR:ecb01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     100060183 (PAK2)
Protein kinases [BR:ecb01001]
 Serine/threonine protein kinases: STE group
  STE20 family
   100060183 (PAK2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
UniProt: 
Position
19
AA seq 524 aa AA seqDB search
MSDNGELEDKPPAPPVRMSSTIFSTASKDPLSANHSLKPLPSVPEEKKPRNKIISIFSGT
EKGSKKKEKERPEISPPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKLEQKKNP
QAVLDVLKFYDSNTVKQKYLSFTPPEKDGFPSGTPALNTKGSETPAVVTEEDDDDEEAAP
PVIAPRPDHTKSIYTRSVIDPIPAPVGESSVDGGPKSSDKQKKKTKMTDEEIMEKLRTIV
SIGDPKKKYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEILVMKE
LKNPNIVNFLDSYLMGDELFVVMEYLAGGSLTDVVTETCMDEAQIAAVCRECLQALEFLH
ANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAY
GPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRC
LEMDVEKRGSAKELLQHPFLKLAKPLSSLTPLIMAAKEAMKSNR
NT seq 1575 nt NT seq  +upstreamnt  +downstreamnt
atgtctgataacggagaactggaagacaagcctccggcgcctcccgtgcgaatgagcagc
accatttttagcactgcaagcaaagatcctttgtcagctaatcacagtttgaaacctttg
ccctctgttccagaggagaaaaagcccaggaataaaatcatctctatcttctcaggcaca
gaaaaaggaagtaagaagaaagagaaggaacggccagaaatttctcctccatctgatttt
gagcacactatccatgttggctttgatgctgttactggagaattcacaggcatgccagaa
cagtgggctcgattattacagacctccaatatcaccaaactagagcaaaagaagaatcct
caggctgtgctggatgtcttaaagttctatgactccaacacagtgaaacagaaatacctg
agctttactcctcctgagaaggatggcttcccttctggaacaccagcactgaataccaag
ggatcagagacaccagcagtagtaacagaggaggacgatgatgatgaagaggctgctccc
cctgttattgccccacgaccggatcatacaaaatcaatttatacacggtctgtaatagac
cctattcctgcaccagttggtgaatctagtgttgatggtggtcctaagtcttctgacaaa
cagaaaaagaagaccaaaatgacagatgaagagattatggagaaattaagaactatcgtg
agcataggtgaccctaagaaaaaatatacaagatatgagaaaattgggcaaggggcttct
ggtacagttttcactgctaccgatgtggcattggggcaggaggttgctatcaaacaaatt
aatttacagaaacagccaaagaaggaattgatcattaatgagattctggtaatgaaagaa
ttaaagaatcccaacatagttaacttcttggacagttacctgatgggagatgaattgttt
gtggtgatggaataccttgctgggggatcgcttactgatgttgtaacagaaacctgcatg
gacgaagcacagatcgctgccgtatgcagagagtgtttacaggcattggagtttttacat
gctaatcaagtgatccacagagacataaaaagtgacaatgtgctattggggatggaagga
tcagttaaacttactgactttggtttctgcgcccagatcacccctgagcagagcaagcga
agtaccatggttggaacgccatactggatggcaccagaggtggtcacacggaaggcttat
ggccctaaagtggacatatggtctctgggtatcatggctattgagatggtggaaggagag
cctccttacctcaacgaaaatcccttgagggcattgtatctgatagcaactaatggaacc
ccagaacttcagaatccagagaagctttctccaatatttcgggatttcttaaatcgatgt
ttggagatggatgtggagaaaagaggttcagccaaagaattgttacagcatcccttcctg
aaactggccaaaccattgtctagcttgacgccgctgatcatggcagccaaagaagcgatg
aagagtaaccgttag

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