| Entry |
|
|---|
| Gene name |
XIAP
|
|---|
| Definition |
(RefSeq) X-linked inhibitor of apoptosis
|
|---|
| KO |
| E3 ubiquitin-protein ligase XIAP [EC: 2.3.2.27] |
|
|---|
| Organism |
ecb Equus caballus (horse)
|
|---|
| Pathway |
| Platinum drug resistance | | NF-kappa B signaling pathway | | Ubiquitin mediated proteolysis | | Apoptosis | | Apoptosis - multiple species | | Necroptosis | | Focal adhesion | | NOD-like receptor signaling pathway | | Toxoplasmosis | | HTLV-I infection | | Pathways in cancer | | Small cell lung cancer |
|
|---|
| Brite |
KEGG Orthology (KO) [BR:ecb00001]
Genetic Information Processing
Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
100060870 (XIAP)
Environmental Information Processing
Signal transduction
04064 NF-kappa B signaling pathway
100060870 (XIAP)
Cellular Processes
Cell growth and death
04210 Apoptosis
100060870 (XIAP)
04215 Apoptosis - multiple species
100060870 (XIAP)
04217 Necroptosis
100060870 (XIAP)
Cellular community - eukaryotes
04510 Focal adhesion
100060870 (XIAP)
Organismal Systems
Immune system
04621 NOD-like receptor signaling pathway
100060870 (XIAP)
Human Diseases
Cancers
05200 Pathways in cancer
100060870 (XIAP)
05222 Small cell lung cancer
100060870 (XIAP)
Infectious diseases
05166 HTLV-I infection
100060870 (XIAP)
05145 Toxoplasmosis
100060870 (XIAP)
Drug resistance
01524 Platinum drug resistance
100060870 (XIAP)
Enzymes [BR:ecb01000]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
100060870 (XIAP)
Ubiquitin system [BR:ecb04121]
Ubiquitin ligases (E3)
Single Ring-finger type E3
Other single Ring-finger type E3
100060870 (XIAP)
Mitochondrial biogenesis [BR:ecb03029]
Mitochondrial quality control factors
Mitochondrial dynamics
Retention of mitochondria
100060870 (XIAP)
 |
|---|
| SSDB |
   |
|---|
| Motif |
 |
|---|
| Other DBs |
NCBI-GeneID: NCBI-ProteinID: Ensembl: UniProt: |
|---|
| Position |
X
|
|---|
| AA seq |
494 aa  
MTFNSFEGSKTCVPADIDKDEEFVEEFNRLKTFANFPSSSPVSASTLARAGFLYTGEGDT
VQCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFINGFYFENNAAQPTNPGVQNGQYKVENY
LGNRNHFVLGRPSETHAEYLLRTGQVVDISDTIYPRNPAMCSEEARLKSFQNWPDYAHLT
PGELASAGLYYTGIDDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNVNIRSE
SDVVSSDRNFSNSTNLPRNPAMADYEARIITFGTWIYSVNKEQLARAGFYALGEGDKVQC
FHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEEKGQEYISNIHLTCSLEESLVRTAEKTT
ERIDDTIFRNPMVQEAIRMGFSFRDIKKIMEEKIHTSGSNYRSLEILVADLVNAQKDNTQ
DESSQTSLQQEISAEEQLRLLQEEKLCKICMDRNIAVVFIPCGHLVTCKQCAEAVDKCPM
CNTVITFKQKIFMS |
|---|
| NT seq |
1485 nt  +upstreamnt +downstreamnt
atgacttttaacagttttgaaggatctaaaacttgtgtacctgcagacatcgataaggat
gaagaatttgtagaagagtttaatagattaaaaacttttgctaattttccaagtagtagt
cctgtttcagcctcaacactagcacgagctggttttctctatactggtgaaggggacact
gtgcagtgctttagttgtcacgcagcagtagatagatggcaatatggagactcagcagtt
ggaagacacaggaaagtatccccaaattgcagatttatcaatggcttttattttgaaaat
aatgctgcgcaacctacaaatcctggtgtccagaatggtcagtacaaagttgaaaactat
ctgggaaacagaaatcattttgttttaggcaggccatctgagactcatgcagaatacctt
ttgagaactggacaggttgtagacatatcagataccatatacccgaggaaccctgccatg
tgtagtgaagaagctagattaaagtcatttcaaaattggccagactatgcccacttaacc
ccaggagagttagctagtgctggactctactacacaggtattgatgatcaagtgcagtgc
ttttgttgtggtggaaaactgaaaaactgggaaccttgtgatcgtgcgtggtcagaacac
aggcgacactttcctaattgcttctttgttttgggccggaatgttaatattcgaagtgaa
tctgatgtcgtgagttctgataggaatttctcaaattcaacaaatcttccaagaaatcca
gccatggcagattatgaagcacggatcattacttttgggacgtggatatactcagttaac
aaggagcagcttgcaagagctggattttatgctttaggtgaaggtgataaagtgcagtgc
tttcactgtggaggagggctaactgattggaagcccagtgaagatccttgggaacaacat
gctaagtggtatccagggtgtaaatatctgttagaagagaaggggcaggagtatataagc
aatattcatttaacctgttcactggaggagtctctggtaagaactgctgaaaaaacaact
gaaagaattgatgataccatcttccgcaatcccatggtacaagaagctatacgaatggga
ttcagtttcagggacattaagaaaataatggaggaaaaaattcacacatctgggagcaac
tatagatcactcgaaattttggttgcagatctagtgaatgctcagaaagacaatacacaa
gatgaatcaagtcagacttcattgcagcaagagattagtgctgaagagcagctaaggctc
ctgcaagaggagaagctttgcaaaatctgcatggatagaaatattgctgtagtttttatt
ccttgtggacatctggtcacttgtaaacaatgtgctgaagcagttgacaaatgtcccatg
tgcaacacagtcattactttcaagcaaaaaatttttatgtcttaa |
|---|
