KEGG   Equus caballus (horse): 100061645Help
Entry
100061645         CDS       T01058                                 

Gene name
CACNA2D2
Definition
calcium channel, voltage-dependent, alpha 2/delta subunit 2
Orthology
K04859  
voltage-dependent calcium channel alpha-2/delta-2
Organism
ecb  Equus caballus (horse)
Pathway
MAPK signaling pathway
Cardiac muscle contraction
Adrenergic signaling in cardiomyocytes
Oxytocin signaling pathway
Hypertrophic cardiomyopathy (HCM)
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ecb00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    100061645 (CACNA2D2)
 Organismal Systems
  Endocrine system
   04921 Oxytocin signaling pathway
    100061645 (CACNA2D2)
  Circulatory system
   04260 Cardiac muscle contraction
    100061645 (CACNA2D2)
   04261 Adrenergic signaling in cardiomyocytes
    100061645 (CACNA2D2)
 Human Diseases
  Cardiovascular diseases
   05410 Hypertrophic cardiomyopathy (HCM)
    100061645 (CACNA2D2)
   05412 Arrhythmogenic right ventricular cardiomyopathy (ARVC)
    100061645 (CACNA2D2)
   05414 Dilated cardiomyopathy (DCM)
    100061645 (CACNA2D2)
Ion channels [BR:ecb04040]
 Voltage-gated cation channels
  Ca2+ channel, CACN alpha-2 delta
   100061645 (CACNA2D2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Position
16
AA seq 1089 aa AA seqDB search
MQHWARRLEQEIDGVMRIFGGVQQLREIYKDNRNLFEVQENEPQKLVEKVAGDIESLLDR
KVQALKKLADAAENFQKAHRWQDNIKEEDIMYYDAKADAELDDPESEDVERGSKASNLRL
DFVEDSNFKNKVNYSYTAVQIPTDIYKGSTVILNELNWTEALENVFIENRRQDPTLLWQV
FGSATGVTRYYPATPWRAPKKIDLYDVRRRPWYIQGASSPKDMVIIVDVSGSVSGLTLKL
MKTSVCEMLDTLSDDDYVNVASFNEKAQPVSCFTHLVQANVRNKKVFKEAVQGMVAKGTT
GYKAGFEYAFDQLQNSNITRANCNKMIMMFTDGGEDRVQDVFEKYNWPNRTVRVFTFSVG
QHNYDVTPLQWMACANKGYYFEIPSIGAIRINTQEYLDVLGRPMVLAGKEAKQVQWTNVY
EDALGLGLVVTGTLPVFNLTQDGPGEKKNQLILGVMGIDVALNDIKRLTPNYTLGANGYV
FAIDLNGYVLLHPNLKPQTTNFREPVTLDFLDAELEDENKEEIRRSMIDGNKGHKQIRTL
VKSLDERYIDEVMRNYTWVPIRSTNYSLSNPSGAAHYSPQDPQSHQGLSLALQEQAPSPG
MPISKLKDFEFLLPSSFESEGHVFIAPREYCKDLNASDNNTEFLKNFIELMEKVTPDSKQ
CNNFLLHNLILDTGITQQLVERVWRDQDLNTYSLLAVFAATDGGITRIFPNKAAEDWTEN
PEPFNASFYRRSLDNHGYVFKPPHQDALLRPLELENDTVGILVSTAVELSLGGRTLRPAV
VGVKLDLEAWAEKFKVLASNRTHQDQPQKCGPSSHCEMDCEVNNEDLLCILIDDGGFLVL
SNQNHQWDQVGRFFSEVDANLMMALYNNSFYTRKESYDYQAACAPQPQGNLGAAPRGVFV
PTVADFLNLAWWTSAAAWSLFQQLLYGLISHSWFQADPAEAESNPEARESSCVMKQTQYY
FGSVNASYNAIIDCGNCSRLFHAQKLINTIIYFMGAEKTLCSQSKAGRLMQKXTHTDGPE
QCELVQRPRYRRGPHICFDYNATEDTSDCGRGASFPPSLGVLVSLQLLLLLGLPPRPQPQ
VYAYASRRL
NT seq 3270 nt NT seq  +upstreamnt  +downstreamnt
atgcagcactgggcccggcgcctggagcaggagatcgatggtgtgatgcggatctttggg
ggcgtccagcagctccgtgagatctacaaggataaccggaatctgtttgaggtgcaggag
aacgagcctcagaagttggtggagaaggtggcgggagatattgagagcctgctggacagg
aaggtgcaggccctaaagaaattggccgatgctgcagagaacttccagaaagcccaccgc
tggcaggacaacatcaaggaggaagacatcatgtactatgacgccaaggccgacgctgag
ctggacgaccctgagagcgaggatgtggagagggggtccaaggccagcaatctaaggctg
gacttcgttgaggactcaaacttcaagaacaaggtcaactattcatacacggccgtgcag
atccccacggatatctacaaaggctccaccgtcatccttaatgagctcaactggacagag
gccttggagaatgtgttcatcgagaaccgcaggcaggaccccacactgctgtggcaggtc
ttcggcagtgcaacgggagtcactcgctactatccagccaccccgtggcgagcccccaag
aaaatcgacctgtacgatgtccgaaggagaccctggtatatccagggggcctcgtcgccc
aaggacatggtcatcattgtggatgtgagtggaagcgtgagcggcctgaccctgaagctg
atgaagacatctgtctgtgagatgctggacacgctgtccgacgatgactacgtgaatgtg
gcctcattcaacgagaaggcgcagcctgtgtcatgcttcacacacctcgtgcaggccaat
gtgcgtaacaagaaggtgttcaaggaagctgtgcagggcatggtggccaagggcaccaca
ggttacaaggccggctttgagtatgccttcgaccagctacagaactccaacatcactcgt
gccaactgcaataagatgatcatgatgttcacggacggcggtgaggaccgcgtgcaggac
gtctttgagaagtacaattggcctaaccggacggtacgcgtgttcactttttccgtgggg
cagcacaactacgatgtcacacccctgcagtggatggcctgcgccaacaaaggttactat
tttgagatcccttccatcggcgccatccgcatcaacacgcaggaatatctagacgtattg
ggcaggcccatggtgctggcaggcaaggaggccaagcaggtgcaatggaccaacgtgtat
gaggatgcactgggactggggttggtggtaacagggaccctccccgttttcaacctgacg
caggatggtcctggagaaaagaagaaccagctgatcctgggcgtgatgggcatagatgtg
gctctgaatgacattaagaggctgactcccaactacacgcttggagccaacggctacgtg
tttgccattgacctgaatggctatgtgttgctgcaccccaacctcaagcctcagaccacc
aacttccgggaacctgtgactttggacttcctggatgcagagctggaggatgagaacaag
gaggagatacgtcggagtatgatcgatggtaacaagggccacaagcagatcagaacactg
gtcaagtccctggacgagaggtacatagacgaggtgatgcggaactacacctgggtgccc
ataaggagcaccaactacagtttgtcaaatcccagtggggctgctcactactcaccccag
gaccctcagtcccaccagggcctctcgctagcccttcaggaacaagctccatctcctggg
atgccaatcagcaaactgaaggattttgagttcctgctccccagcagctttgagtctgaa
ggacatgttttcattgctcccagagagtattgcaaggacctgaatgcctcagacaacaac
accgagttcctgaaaaacttcattgagctcatggagaaagtgactccagactccaagcag
tgcaacaacttccttctgcacaacctgatcttggacacaggaatcacacagcagctggtg
gagcgtgtgtggcgggaccaggatctcaacacgtacagccttctggccgtgtttgccgcc
accgacggtggcatcactcgcatattccccaacaaggcagctgaggactggacagagaac
cctgagcccttcaatgccagcttctaccgccgcagcctggataaccacggctatgtcttc
aagcccccacaccaggatgctctgttaaggccactggagctggagaatgacacagtgggc
atcctcgtcagcacggctgtggagctcagcctgggtggacgcacactgaggccagcagtg
gtaggcgttaagctggacctagaggcctgggctgagaagttcaaggtgctagccagcaac
cgtacccatcaggaccagcctcagaagtgcggccccagcagccactgtgagatggactgt
gaggttaacaatgaggacctgctctgtatcctcattgatgacgggggattcctggtgctg
tcaaaccagaaccatcagtgggaccaggtgggcaggttcttcagtgaggtggatgccaac
ctgatgatggcactctacaataattccttctacacccgcaaggagtcctatgactatcaa
gcagcctgtgccccccagccccagggcaatctgggtgctgcaccccggggggtctttgtg
cccacggttgcagacttccttaacctggcctggtggacctcagctgctgcctggtccttg
ttccagcagcttctctatggcctcatctcccacagctggttccaggcagaccccgcggag
gccgagagcaaccccgaggcgcgcgagagcagctgcgtcatgaaacagacccagtactac
ttcggttcagtgaacgcctcctacaacgccattatcgactgcggaaactgctccaggcta
ttccacgcgcagaagctgatcaacaccatcatttacttcatgggggcggagaagacgctg
tgcagccagagtaaggcaggccggctgatgcagaagtagacacacacggacggcccggag
cagtgtgaactggtacagagaccgcgataccggagaggtccgcacatctgcttcgactac
aacgcaacggaagatacctcagactgtggccgtggagcctccttcccgccgtcgctgggc
gtcctggtctccctgcagctgctgctgctcctgggcctgcctccccggccacagcctcaa
gtctacgcctacgcctctcgccgcctctga

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