KEGG T01058: 100061676

Equus caballus (horse): 100061676

Entry

100061676 CDS T01058

Gene name

PLCE1

Definition

phospholipase C, epsilon 1

Orthology

K05860

phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]

Organism

ecb Equus caballus (horse)

Pathway

ecb00562	Inositol phosphate metabolism
ecb01100	Metabolic pathways
ecb04020	Calcium signaling pathway
ecb04070	Phosphatidylinositol signaling system
ecb05205	Proteoglycans in cancer

Module

ecb_M00130

Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4

Class

Metabolism; Carbohydrate metabolism; Inositol phosphate metabolism [PATH:ecb00562]
Environmental Information Processing; Signal transduction; Calcium signaling pathway [PATH:ecb04020]
Environmental Information Processing; Signal transduction; Phosphatidylinositol signaling system [PATH:ecb04070]
Human Diseases; Cancers; Proteoglycans in cancer [PATH:ecb05205]

SSDB

Motif

Pfam:

PI-PLC-X PI-PLC-Y RasGEF RA EF-hand_like C2 GDPD

Other DBs

NCBI-GI:

194205841

NCBI-GeneID:

100061676

Position

AA seq 2299 aa
MTSEEMAASVLIPVTQRKVISVQGAVDESSEKVSDISVPKVHTIRQSGPTSHAISQLNTL
KEESSGSNLPKIFSIAREKIMSDENSNEKCWEKTMPDSVKNLNINCNNILKNLPQSQFYE
TCDSVTEEGLCMETGIPSSLERKVFPGIQLEIDGPPKDVSPLGNQSAIMDTSRARSDSNM
AVFHFHYEVDRGMSDTFCTLSDNLILDDCGNCVPLPGVGGEQKKNYMAYTCKLMELAKNC
DNKNGQLQCDHCDTLNDKYLCFEGSCQKANVVCSSDSFCKEDFTDSPPAKTFLSHLEDFP
DNCEDVEEDFFKSKKERSTLLVRRFCKNDREVKKSVYTGTRAIVRTLPSGHIGLGAWSYI
DQKRNGLLLPCGRVTERLSTVVTGQDGSRCLSEAQWYPIYTAVRRGEGTEDTIGSLLHVF
TELPASERAHERISIGLCLKQCVRDTVCEYRATLQRTSISQYITGSLLEATTSLGARSGL
LNTFGGSTGRMMMKERQPGTSMANSSALPSSSAGISKELIDLQPLIQFPEEVASILMEQE
QNIYRRVLPVDYLCFLTRDLGTPECQRSLPCLKASISASILTSQNGEHNALEDLLMRFNE
VSSWVTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGLRSRKVLKMWQFM
DQSDLETMRSLKDAMAQHESSCEYRKVVTRALHIPGCKVVPFCGVFLKELCEALDGASGL
MKLCPRYNSQEETLEFVADYSGQDNFLQRVGQNGLKNSEKESTVNSIFQIIRSCSRSLET
EEEDSPSEGNSSRKNSLKDKARWQFIIGDLLDSENDIFEQPKEWDPHGSEEPQKAFDHGT
ELIPWYVLSIQADVHQFLLQGATVIHYDQDMHLSARCFLRLQPDNSTLTWMKPTTASPAS
AKAKLGVLSNTSEPGKFPLLGSAGLSSLVEGVLDLFSAKAVYMGHPSIDIHTVCVQNKLG
SMLLSETGVTLLYGLQTTDNRLLHFVAPKHTAKMLFSGLLELTKAVRKMRKFPDQRQQWL
RKQYVSLYQEDGRYEGPTLAHAVELFGGRRWSTRNPSPGTSAKSAEKPNVQRNNTLGIST
TKKKKKILMRGESGEATDDEMATRKVKVHKECRSRSGSDPQDANEPEESEANAITSPPNP
LPSRRAHSLTTAGSPNLASGTSSPIRPVSSPVLSSSNKSPSSAWSSSSWHGRIKGGMKGF
QSFMVSDSNMSFIEFVELFKSFSVRSRKDLKDLFDIYAVPCNRAGSESAPLYTNLTIDEN
TSGLQPDLDLLTRNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGIESTSLGIFG
VGILQLNDFLVNCQGEHCTYDEILSIIQKFEPSVSMCHQGLMSFEGFARFLMDKDNFASK
NDESQENSRELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSIELDCWDG
DDGMPIIYHGHTLTTKIPFKEVVEAIDRSAFITSDLPIIISIENHCSLPQQRKMAEIFKT
VFGEKLVAKFLFESDFSDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDILKQKAHQLASMQ
AQAYNGGNANPPPANNEEEEDEEDEYDYDYESLSDDNILEDRPENKSCNDKLQFEYNEEI
PKRIKKADNSACNKGKVYDMELGEEFYLPQNKKESRQIAPELSDLVIYCQAVKFPGLSTL
NASGSSRGKERKSRKSIFGNNPGRMSPGETASFNKTSGKSSYEGMRQAWEESSSPLNPTT
SLSAIIRTPKCYHISSLNENAAKRLCRRYSQKLIQHTACQLLRTYPAATRIDSSNPNPLM
FWLHGIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLERDL
DNMEPAVYSLSIVSGQNVCPSNSTGSPCIEVDVLGMPLDSCHFRTKPIHRNTLNPMWNEQ
FLFRVHFEDLVFLRFAVVENNSSAVTAQRVIPLKALKRGYRHLQLRNLHNEILEISSLFI
NSRRMEENSSSNTVPSSLMFNTEERKCLQTHRVTVHGVPGPEPFTVFSINGGTKAKQLLQ
QILATEQDTKPIATDYFLMEEKYFISKEKNECRKQPFQRAIGPEEEIMQILSSWFPEEGY
VGRIVLKTQQENLEEKNIVPEDKEVILSSEEESFFVQVHDVSPEQPRTVIKAPRVSTAQD
VIQQTLCKAKYSYSILSNPNPSDYVLLEEVVKDTTNKKSSTPKSSQRVLLDQECVFQAQS
KWKGAGKFILKLKEQVQASREDKRKGISFASEFKKLTKSTKQPRGLTSPSQVLASESVQN
KEEKPVGSLSSSDTTDYRQ

NT seq 6900 nt +upstreamnt +downstreamnt
atgacttctgaagaaatggcagcttctgttctcatacctgtgactcagagaaaagtgata
tctgttcaaggggctgttgatgaaagtagtgaaaaggtctcagacatcagtgttccaaaa
gtgcatactatcagacagagtgggccaacttctcatgccatctcacaactgaacacactt
aaagaagaatcttctggaagcaacttgcccaagattttctccatagcaagggagaaaata
atgagtgacgagaacagtaatgaaaagtgctgggagaaaaccatgccagattctgtgaaa
aaccttaacattaactgtaacaacatattgaaaaaccttcctcagagccagttttatgaa
acatgtgattctgtcacagaggaaggcctgtgtatggaaactggaatcccttcttcactg
gaaagaaaggtgttccctggaattcaactggaaatagacggacctcccaaggacgttagt
cccttaggaaatcaatcagcgatcatggataccagcagggcacgctctgacagcaacatg
gcggtatttcactttcactatgaagttgacagaggaatgtcagacactttctgtaccctg
tcagataacttgattttggatgattgtggaaactgtgtaccactgcctggtgttggtgga
gagcaaaagaaaaattacatggcgtatacttgtaaactgatggaattggcaaaaaactgt
gataataagaatggacagctgcagtgtgatcattgtgacaccttgaatgacaaatacttg
tgctttgaaggttcttgccagaaggccaatgtggtatgttcaagcgacagcttttgcaag
gaggattttactgacagtcctcctgcgaagacctttctgagccatttggaagacttccct
gataattgtgaagatgtagaagaagattttttcaaaagcaaaaaggagcgatccactttg
ttagtgaggagattttgtaaaaatgacagggaagttaagaaatctgtgtacactgggaca
agggcaattgtgagaactctgccttctggtcacattgggctgggagcttggagttacatt
gatcagaagagaaatggtctcttgttgccctgtgggagagtaacggaacggctgtcaaca
gtggtgactgggcaagatgggagccggtgtctgtcagaagcccagtggtatccgatctac
actgcagtgagaaggggagaaggaacagaagatacaattggatctcttctccatgtcttc
acagagctcccagcctctgagagagcccatgaaaggattagcattggtctgtgcttaaag
caatgtgtccgagacaccgtgtgtgagtatcgtgccaccctccaaaggacttccatatcg
cagtacatcaccggttctctcctagaagcaaccacatctttaggagcacgaagtggcctt
ctcaatacttttggaggatccactggacgaatgatgatgaaagaacgccaaccgggcacc
tctatggccaattccagtgccctcccttcaagttccgctgggatcagcaaggaactgatt
gatctgcagcccctcatccagttcccagaagaggtcgccagcatcctgatggagcaggag
cagaatatttaccgaagggtcttgccagttgactatctttgcttcttgacccgggacttg
ggcactccggaatgccagaggtctctgccctgcctcaaagcgtccatctcagcatcaatt
cttacctcccagaacggagaacacaatgcccttgaagatctcctgatgagatttaatgag
gtgagctcctgggtaacgtggctgatcctcaccgcgggctccatggaggagaagcgggaa
gtcttctcatatttggtgcatgtggccaaatgctgctggaacatgggcaactacaatgct
gtcatggagttcttggctggcctcaggtcaagaaaagttttaaaaatgtggcagttcatg
gaccagtctgacctggagaccatgaggagcctgaaggatgccatggctcagcacgaatct
tcctgtgagtacaggaaggtggtgacgcgggcactgcacatccccggctgtaaggtggtt
ccgttctgtggggtgtttctgaaggagctgtgtgaagcgcttgacggagcctccggcctc
atgaagctttgcccgaggtacaattcccaggaagaaactctagagtttgtagctgattat
agtggacaagataatttcttacaacgtgtgggacaaaatggcttaaagaattcagagaag
gagtccacagtcaacagcatctttcagatcatcagaagctgtagtcgaagtctcgagacc
gaggaggaggacagccccagtgaagggaacagctctaggaaaaattccttgaaggataaa
gccagatggcagtttataattggagatttgctagattctgaaaatgacatctttgagcag
cccaaagaatgggaccctcatggatcagaagagccacagaaggcgtttgaccatgggaca
gagctcatcccgtggtacgtgctgtctatccaagctgatgtgcaccagttcctgttgcag
ggggccacggtcatccactacgaccaggacatgcacctctctgcccgctgcttcctccgg
cttcagcctgacaatagcaccttgacctggatgaagcccaccactgcctccccagccagt
gctaaagcgaaacttggtgtacttagtaacacgtctgagcctggtaaattcccgttactg
ggcagtgctggattaagcagcctggtggagggggtcttggatctgttttcagcaaaggct
gtgtacatgggacaccctagcattgatatacacactgtgtgtgttcagaacaaactgggt
agcatgcttctctcagagactggtgtaacgctgctctatgggcttcagaccacggacaat
aggttattgcactttgtggcaccaaagcacacagctaaaatgctcttcagcggattgttg
gaactcacgaaagctgtaagaaagatgaggaagttccctgaccaaagacagcagtggctg
cggaaacaatacgtcagcctctatcaggaagatggacggtatgaaggcccaactttggct
catgctgtggagttgtttggtggcagacgatggagtactcgaaaccccagccctgggaca
tcagcaaagagtgccgagaagcccaacgtgcagagaaacaacaccttgggcataagtacc
accaagaaaaagaagaaaatcctgatgaggggtgagagtggagaggcaaccgacgatgag
atggccacccgcaaggtcaaagtgcacaaagagtgtcggagccggagcggttctgaccct
caagatgctaacgaaccagaggaatcagaggcgaatgccatcacgagccctccgaatcct
ctcccttccagaagagcccactctttgaccacggctgggtcccctaacttggcttccggg
acgtcatctcccatcaggccagtgtcctcccctgtgctgtcttcttcaaacaagagcccg
tccagtgcttggagcagcagcagctggcacgggcggatcaaaggaggaatgaagggcttt
cagagcttcatggtttcagacagtaacatgagtttcattgaatttgttgagctgttcaaa
tcattcagtgtacggagccgcaaggacctgaaggatctctttgacatctatgctgtgcca
tgcaaccgagccggctccgagtcggccccgctctacaccaacctcacaatcgatgaaaac
accagcggtcttcagcctgacctagatttgttgaccagaaatgtctcggatttggggttg
ttcattaagagtaaacagcagctgtcagacaaccagaggcagatatccgatgccattgct
gctgcaagtatcgtgacaaacggcactgggatcgagagcacgtccctgggcatatttggg
gtaggcatactccagctcaatgacttcctagtgaattgccaaggagaacattgcacttac
gatgaaatcctcagcatcatccagaagttcgagcccagcgttagtatgtgtcatcagggc
ctaatgtcgtttgaaggatttgcaaggtttctgatggataaagataattttgcctcaaaa
aatgacgagtcacaggagaacagtagagaattgcagctgcccctctcctactactacatt
gaatcttcacacaatacctacctcacaggccatcagctcaaaggagaatcctcagtagaa
ctctacagccaggtcctcctgcaaggctgtaggagcatagagttggactgctgggatgga
gatgatgggatgcccatcatttatcatggacataccctgacaaccaagatccccttcaag
gaagtggttgaagccattgatcgaagtgccttcatcacctctgacctgccaatcatcata
tcaattgagaaccactgttcattgcctcagcaacgaaaaatggcagaaattttcaagact
gtttttggagaaaaactggtggctaaattcttatttgagagtgatttctcagatgatcca
atgcttccctcacctgaccaacttagaagaaaagtgcttcttaaaaataagaagctgaaa
gcccatcagaccccagtggatatcttaaagcaaaaggctcatcagttagcatccatgcaa
gctcaggcatataatggcgggaatgccaaccctccacctgctaataacgaggaagaggaa
gatgaagaggacgaatatgattatgactatgaatccctctctgatgacaacattctagaa
gacagacctgaaaataaatcatgtaatgacaagcttcagtttgagtataatgaagaaatc
cccaagaggataaagaaagcagataactctgcttgcaacaaaggaaaggtttatgacatg
gaactgggagaagaattttatcttcctcagaataaaaaggaaagcagacagattgcacca
gagctttctgacctggtcatctattgccaagcagtaaaatttccaggcctgtcaactcta
aatgcatctggctctagcagaggaaaagaaaggaaaagcaggaagtccatttttggcaac
aatccgggcagaatgagccctggagagacagcatcgtttaacaaaacatctggaaaaagt
tcctatgaaggaatgcgacaggcctgggaggaatcatcttcccccctcaacccaaccacg
tccctcagcgctatcattagaactcccaaatgttaccatatctcgtcgctgaatgaaaat
gccgccaagcgtctgtgtcgcaggtattcccagaaactgatccagcacaccgcctgtcag
ctgctgaggacttacccggccgccacccgcatcgactcgtccaaccccaatcctctcatg
ttctggctccatgggatacagcttgtggccctcaactaccagacagatgatctccctttg
catttaaatgctgccatgtttgaggccaacggtggctgtggttatgttttgaaaccccca
gttctgtgggacaagaactgtcccatgtatcagaagttttctcccttggaaagagacctg
gacaacatggagcctgctgtctattctttatctattgtctctggtcaaaacgtgtgcccg
agtaacagcacgggaagcccgtgtattgaagttgacgtcctgggcatgcccctggacagc
tgccacttccgcacgaagcccatccatcgaaataccctgaaccccatgtggaacgaacag
tttctcttccgggttcactttgaagatctcgtatttctccgttttgcagttgtggaaaac
aatagctcggcggtaactgctcagagggtcattccactcaaggctttaaaacgaggatat
cgacatcttcagctacgaaacctccacaatgaaatcttggagatctccagtttattcata
aacagcagaaggatggaagaaaattcctccagcaatactgtgccgtcctctttgatgttt
aatacagaagaaagaaaatgtttgcagactcacagagtcacggtgcatggggtccctggt
ccagagccctttactgttttctctataaatggaggcacaaaggcaaagcagcttctccag
caaattctggccactgaacaagacaccaaacctattgccacagactattttttgatggaa
gaaaaatatttcatatctaaagaaaagaatgaatgcaggaaacaacccttccagagagcc
attggtccagaagaagagatcatgcagattttaagcagctggtttccagaagaaggatat
gttggcaggattgtcttgaaaacccagcaggaaaacctagaagagaaaaacattgttcca
gaggacaaggaggtgatcctgagctcggaggaggagagcttctttgtccaagtgcacgac
gtttctccggagcaacctcgaacagtcatcaaagcgcctcgagtcagcacggcgcaggac
gtcattcagcagaccttatgcaaagccaaatattcctatagcatcctgagcaaccccaac
ccaagtgactatgtgcttttggaagaggtagtgaaagacacgaccaacaagaagtcttct
accccgaagtcctcccagcgggtccttttggatcaggagtgtgtgtttcaagcacaaagc
aagtggaaaggtgcaggaaaattcatccttaagctaaaggagcaggtacaggcatcccga
gaagacaaaagaaaaggcatatcttttgccagtgaattcaagaagctcaccaagtcaact
aaacagccccgaggactcacatcgccttctcaggtcttggcctcagaaagtgtccaaaac
aaggaggagaagcctgtgggcagcttgtcctccagtgacacgacagactatcgacagtga

All links

Pathway (6)   
   KEGG PATHWAY (5)   
   KEGG MODULE (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (7)   
   Pfam (7)   
All databases (26)   

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