KEGG   Equus caballus (horse): 100070545Help
Entry
100070545         CDS       T01058                                 

Gene name
PLCG1
Definition
phospholipase C, gamma 1
Orthology
K01116  
phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
Organism
ecb  Equus caballus (horse)
Pathway
Inositol phosphate metabolism
Metabolic pathways
ErbB signaling pathway
Ras signaling pathway
Rap1 signaling pathway
Calcium signaling pathway
NF-kappa B signaling pathway
HIF-1 signaling pathway
Phosphatidylinositol signaling system
VEGF signaling pathway
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
Leukocyte transendothelial migration
Neurotrophin signaling pathway
Inflammatory mediator regulation of TRP channels
Thyroid hormone signaling pathway
Epstein-Barr virus infection
Pathways in cancer
Proteoglycans in cancer
MicroRNAs in cancer
Glioma
Non-small cell lung cancer
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:ecb00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    100070545 (PLCG1)
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    100070545 (PLCG1)
   04015 Rap1 signaling pathway
    100070545 (PLCG1)
   04012 ErbB signaling pathway
    100070545 (PLCG1)
   04370 VEGF signaling pathway
    100070545 (PLCG1)
   04064 NF-kappa B signaling pathway
    100070545 (PLCG1)
   04066 HIF-1 signaling pathway
    100070545 (PLCG1)
   04020 Calcium signaling pathway
    100070545 (PLCG1)
   04070 Phosphatidylinositol signaling system
    100070545 (PLCG1)
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    100070545 (PLCG1)
   04660 T cell receptor signaling pathway
    100070545 (PLCG1)
   04664 Fc epsilon RI signaling pathway
    100070545 (PLCG1)
   04666 Fc gamma R-mediated phagocytosis
    100070545 (PLCG1)
   04670 Leukocyte transendothelial migration
    100070545 (PLCG1)
  Endocrine system
   04919 Thyroid hormone signaling pathway
    100070545 (PLCG1)
  Nervous system
   04722 Neurotrophin signaling pathway
    100070545 (PLCG1)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100070545 (PLCG1)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    100070545 (PLCG1)
   05206 MicroRNAs in cancer
    100070545 (PLCG1)
   05205 Proteoglycans in cancer
    100070545 (PLCG1)
   05214 Glioma
    100070545 (PLCG1)
   05223 Non-small cell lung cancer
    100070545 (PLCG1)
  Infectious diseases
   05169 Epstein-Barr virus infection
    100070545 (PLCG1)
Enzymes [BR:ecb01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     100070545 (PLCG1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
Position
22
AA seq 1178 aa AA seqDB search
MEFRLKTLSLQATSEEEVNMWIKGLTWLMEDTLQAATPLQIERWLRKQFYSVDRNREDRI
SAKDLKNMLSQVNYRVPNMRFLRERLTDLEQRSSDITYGQFAQLYRSLMYSAQKTMDLPF
LEASALRAGERPELCRVSLPEFQQFLLEYQGELWAVDRLQVQEFMLSFLRDPLREIEEPY
FFLDEFVTFLFSKENSVWNSQLDAVCPDTMNNPLSHYWISSSHNTYLTGDQFSSESSLEA
YARCLRMGCRCIELDCWDGPDGMPVIYHGHTLTTKIKFSDVLHTIKEHAFVASEYPVILS
IEDHCSIAQQRNMAQYFKKVLGDTLLTKPVDIAADGLPSPNQLKRKILIKHKKLAEGSAY
EEVPTSVMYSENDISNSIKNGILYLEDPVNHEWYPHYFVLTSSKIYYSEETNSDQGNEDE
EEPKETSGSTELHSNEKWFHGKLGAGRDGRHIAERLLTEYCIETGAPDGSFLVRESETFV
GDYTLSFWRNGKVQHCRIHSRQDAGTPKFFLTDNLVFDSLYDLITHYQQVPLRCNEFEMR
LSEPVPQTNAHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKI
KHCRVQQEGQTVMLGNSEFDSLVDLISYYEKHPLYRKMKLRYPINEEALEKIGTAEPDYG
ALYEGRNPGFYVEANPMPTFKCAVKALFDYKAQREDELTFTKSAIIQNVEKQEGGWWRGD
YGGKKQLWFPSNYVEEMVSPAALEPEREHLDENSPLGDLLRGVLDVPACQIAIRPEGKNN
RLFVFSISMASMAHWSLDVAADSQEELQDWVKKIREVAQTADARLTEGKMMERRKKIALE
LSELVVYCRPVPFDEEKIGTERACYRDMSSFPETKAEKYVNKAKGKKFLQYNRLQLSRIY
PKGQRLDSSNYDPLPMWICGSQLVALNFQTPDKPMQMNQALFMAGGHCGYVLQPSTMRDE
AFDPFDKSSLRGLEPCAICIEVLGARHLPKNGRGIVCPFVEIEVAGAEYDSTKQKTEFVV
DNGLNPVWPAKPFHFQISNPEFAFLRFVVYEEDMFSDQNFLAQATFPVKGLKTGYRAVPL
KNNYSEDLELASLLVKIDVFPAKENGDLSPFSGTSLRERGSDASGQLFHGRAREGSFEAR
YQQPFEDFRISQEHLADHFDSRERRAPRRTRVNGDNRL
NT seq 3537 nt NT seq  +upstreamnt  +downstreamnt
atggaattccgcctgaagaccctgagcctgcaagctacatccgaggaggaagtgaacatg
tggatcaagggcttaacttggttgatggaggatactttgcaggcggccacacccctgcag
attgagaggtggctgcggaagcagttctactcagtggatcgaaaccgtgaggaccgtata
tcagccaaggacctgaagaacatgctgtcccaggtcaactaccgggtccccaacatgcgc
ttccttcgagagcggctaacggacctggagcagcgcagcagcgacatcacctatgggcag
tttgctcagctgtaccgcagcctcatgtacagcgcccagaagacgatggacctccctttc
ttggaagccagtgccctgagggctggggagcggccagagctctgccgagtgtcacttcct
gagttccagcagtttctcctcgagtaccagggggagctgtgggctgttgaccggctccag
gtgcaggagtttatgctcagcttcctcagagaccccttgcgagagattgaggagccatac
ttcttcctggacgagttcgtcaccttcctattctccaaagagaacagtgtgtggaactca
cagctggatgcagtgtgcccagacaccatgaacaaccctctctctcactactggatctcc
tcctcgcacaatacgtatctgaccggggaccagttctccagcgagtcctccctggaagcc
tatgctcgctgcctgcggatgggctgtcgctgcattgagttggactgttgggacggccca
gacgggatgcctgtcatttaccacggacacacccttaccaccaagatcaagttctcagat
gtcctgcacaccatcaaggagcatgcctttgtggcctcagagtacccggtcatcctgtcc
atcgaggaccactgcagtattgcccagcaaaggaacatggcccagtacttcaagaaggtg
ctcggggacacactcctcaccaagcctgtggacatcgccgcagatgggctgccttcaccc
aatcagctcaagaggaagatccttatcaagcacaagaagctggctgagggtagtgcctat
gaggaggtgcctacatctgtgatgtactcagagaacgacatcagcaactccatcaagaat
ggcatcctctacctggaggaccctgtgaaccatgagtggtatccccactactttgttctg
accagcagcaagatctactactctgaggagaccaacagtgaccagggcaatgaggatgag
gaggagcccaaggagaccagcggcagcacagagctgcactccaacgagaagtggttccat
gggaagctcggggcaggacgggacgggcggcacatcgccgagcgcctgctcaccgagtac
tgcattgagaccggggcccccgatggctccttcctagtgcgcgagagcgagacctttgtg
ggcgactacaccctctctttctggcggaacgggaaagtccagcactgcaggatccactct
cggcaggatgctgggacccccaagttcttcttaacagacaacctcgtctttgactccctc
tatgacctcatcacacactaccagcaggtgcccctgcgctgcaacgaatttgagatgcgc
ctctcagagcctgtcccacagaccaatgcccacgagagcaaagagtggtaccacgcaagc
ctgaccagagcacaggctgagcacatgctgatgcgtgtcccccgtgatggtgcattcctg
gtgcggaaacggaatgagcccaactcttacgccatatccttccgggccgagggcaagatt
aagcattgccgtgtccagcaggagggccagactgtgatgctgggcaactcggagtttgac
agcctcgttgacctcatcagctactatgagaagcatccgctgtaccgcaagatgaaactg
cgctatcccatcaacgaggaggcgctggagaagattggcacagctgagcctgactacggg
gccctgtatgagggacgcaaccctggcttctatgtggaagcaaaccctatgccgactttc
aagtgtgcagttaaagccctctttgactacaaggcccagagagaggatgagctgactttc
accaagagcgccatcatccagaatgtggagaagcaagagggaggctggtggcgaggggac
tatggtgggaagaagcagctgtggttcccatccaactacgtggaagaaatggtcagtcca
gcggccctggagcctgaaagggagcacttggacgagaacagccctctgggggacttgctg
cggggggtcttggatgtgccagcttgtcagattgccatccgtcctgagggcaagaacaac
cggctcttcgtcttctccatcagcatggcgtccatggcacactggtccctggatgttgct
gctgactctcaggaggagctgcaggactgggtgaaaaagatccgagaagtggcccagacc
gcagatgccaggctcactgaggggaagatgatggaacggaggaagaagattgccctggag
ctctccgagcttgttgtctactgccgacctgttccttttgatgaagagaagattggcaca
gaacgtgcctgctaccgggacatgtcatcctttccggaaaccaaggctgagaaatatgtg
aacaaggccaaaggcaagaagttcctccagtacaaccggctccagctctcccgcatctac
cccaagggccagcggctggactcctccaattacgatcccttgcccatgtggatctgtggc
agtcagctggtggccctcaacttccagaccccagacaagcctatgcagatgaaccaggcc
ctcttcatggccggcgggcactgtggctacgtgctgcagccaagcaccatgcgggacgag
gccttcgacccctttgacaagagcagcctccgtgggctagagccatgcgccatctgcatc
gaggtgctgggggcccggcatctgccaaagaatggccgaggcattgtgtgtccttttgtg
gagattgaggtggctggagctgagtatgacagcaccaagcagaagacagagtttgtggtg
gacaatggactgaaccccgtgtggccagccaagcccttccacttccagatcagtaacccc
gaattcgccttcctgcgctttgtagtgtatgaggaagacatgtttagtgaccagaacttc
ctggcccaggctactttcccggtgaaaggcctgaagacaggatatagagcggtgcctttg
aaaaacaactacagtgaggacctggagctggcctccctgctcgtcaagatcgacgttttc
cctgccaaggagaacggcgacctcagtcccttcagtggtacgtccctgcgggaacggggc
tctgatgcctcgggccagctgtttcatggccgggcccgggaaggctcctttgaagcccgc
taccagcagccatttgaggactttcgcatctcccaggagcaccttgcagaccattttgac
agtcgggaacgaagggccccacgaaggactcgggtcaacggagacaatcgcctctag

DBGET integrated database retrieval system