KEGG   Equus caballus (horse): 100071232
Entry
100071232         CDS       T01058                                 
Symbol
ITK
Name
(RefSeq) tyrosine-protein kinase ITK/TSK isoform X1
  KO
K07363  IL2-inducible T-cell kinase [EC:2.7.10.2]
Organism
ecb  Equus caballus (horse)
Pathway
ecb04062  Chemokine signaling pathway
ecb04660  T cell receptor signaling pathway
ecb04670  Leukocyte transendothelial migration
Brite
KEGG Orthology (KO) [BR:ecb00001]
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    100071232 (ITK)
   04670 Leukocyte transendothelial migration
    100071232 (ITK)
   04062 Chemokine signaling pathway
    100071232 (ITK)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ecb01001]
    100071232 (ITK)
Enzymes [BR:ecb01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     100071232 (ITK)
Protein kinases [BR:ecb01001]
 Non-receptor tyrosine kinases
  TEC family
   100071232 (ITK)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 PH SH3_1 BTK SH3_9 SH3_10 SH3_2 SH3_3 PH_8 SH3_4 ABC1
Other DBs
NCBI-GeneID: 100071232
NCBI-ProteinID: XP_001503605
Ensembl: ENSECAG00000009530
VGNC: 19189
UniProt: A0A9L0RA54
Position
14:complement(21071510..21137772)
AA seq 620 aa
MNNFILLEEQLIKKSQQKRRTSPSNFKVRFFVLTKTSLAYFEDRHGKKRTLKGSIELSRI
KCVEIVKSDISIPCHYKYPFQVVHDNYLLYVFAPDRESRQRWVLALKEETRNNNSLVPKY
HPNFWMDGKWRCCAQLEKLAVGCAQYDPTKNASKKPLPPTPEDNRRPLQEPEETLVIALY
DYQANGPQELTLQRNDEYYLLDSSEIHWWRVQDRNGHEGYVPSSYLVEKSPNNLETYEWY
NKSISRDKAEKLLLDTGKEGAFMVRDSRTPGTYTVSVFTKAIVSENNPCIKHYHIKETNE
NPKRYYVAEKYVFDSIPLLINYHQHNGGGLVTRLRYPVCSWRQKAPVTAGLRYGKWVIDP
SELTFVQEIGSGQFGLVHLGYWLNKDKVAIKTIQEGAMSEEDFIEEAEVMMKLSHPKLVQ
LYGVCLEQAPICLVFEFMEHGCLSDYLRNQRGLFAAETLLGMCLDVCEGMAYLEKVCVIH
RDLAARNCLVGENQVIKVSDFGMTRFVLDDQYTCSTGTKFPVKWASPEVFSFNRYSSKSD
VWSFGVLMWEVFSEGKIPYENRSNSEVVEDITTGFRLYKPRLASSHIYQIMNHCWKEKPE
DRPPFSRLLSQLSEIAESGL
NT seq 1863 nt   +upstreamnt  +downstreamnt
atgaacaactttatcctcctggaagaacagctaattaagaaatcccaacaaaagagaaga
acttctccctcgaactttaaagtccgtttctttgttttaaccaaaaccagcctggcgtac
tttgaggatcgtcatgggaagaagcgcacattgaagggctccattgaactctcccgaatc
aaatgtgtggagattgtgaaaagtgacattagcatcccgtgccactataaatacccattt
caggttgtacatgacaactacctcctgtatgtattcgctccagaccgagagagccggcag
cgctgggtgctggcccttaaagaagaaacaaggaataataacagtttggtgcccaagtat
catcctaatttctggatggatgggaagtggaggtgctgcgctcagctggagaagcttgca
gtgggctgtgcccaatacgatccaaccaagaatgcttcaaagaagcctcttcctcctact
cctgaagacaacaggcgaccacttcaggaacctgaagaaaccctggtcattgccttgtat
gactaccaagcaaacggtccgcaggaactcactctccaacgcaatgatgagtactacctg
ctggacagttccgagattcactggtggagagttcaagataggaatgggcatgaaggatat
gtaccaagcagttatctggtggaaaagtcgccaaataacctggaaacctatgagtggtac
aataagagtatcagccgagacaaagctgaaaaacttcttttggacacaggcaaagaagga
gccttcatggtacgagactccaggactccaggaacatacaccgtgtctgtttttaccaag
gccatcgtaagtgagaacaacccctgtatcaagcactatcacatcaaagaaacgaatgag
aaccccaagcgatattatgtggctgaaaagtatgtgtttgactccatccctctcctcatc
aattatcaccaacacaatggaggaggcctggtcacgagactccggtatccagtttgctcc
tggaggcagaaagccccagtcacggcagggctgcgatacggcaaatgggtgatcgatccc
tcggagctcacttttgtgcaggagattggcagcgggcagtttgggctggtgcacctcggc
tactggctcaacaaggacaaggttgccatcaaaaccattcaggaaggggctatgtcggag
gaggatttcatagaggaggctgaagtcatgatgaaactctctcaccccaaactggtccag
ctctatggggtgtgcctggagcaggcccctatctgcctggtgtttgagttcatggaacac
ggctgcctgtcggattacctgcgcaaccagcgggggctctttgctgcagagaccctgctg
ggcatgtgccttgatgtgtgtgagggcatggcctacctggaaaaggtgtgcgtcatccac
agagacctggctgcccggaattgtttagtgggagaaaaccaagtcatcaaggtgtccgac
tttgggatgacaaggttcgtccttgatgatcaatacacctgttccacaggcaccaaattc
ccggtgaagtgggcatccccggaagtcttctctttcaatcgctatagcagcaagtcagat
gtgtggtcatttggtgtgctgatgtgggaagtcttcagtgaaggcaaaatcccgtatgaa
aacagaagcaactcagaggtggtggaagacatcactaccggatttcggttatacaaaccc
cgattagcctcctcacatatctaccaaatcatgaatcattgctggaaagagaaaccagaa
gaccgaccacccttctccagactcttgagtcaactgtctgaaattgcagaatcaggactt
tag

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (4)   
   RefSeq(nuc) (2)   
   GenBank (1)   
   EMBL (1)   
Protein domain (13)   
   Pfam (13)   
All databases (41)   

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