KEGG   Equus caballus (horse): 100071381Help
Entry
100071381         CDS       T01058                                 

Gene name
HADHA
Definition
hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
Orthology
K07515  
enoyl-CoA hydratase / long-chain 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.211]
Organism
ecb  Equus caballus (horse)
Pathway
Fatty acid elongation
Fatty acid degradation
Valine, leucine and isoleucine degradation
Lysine degradation
Tryptophan metabolism
beta-Alanine metabolism
Propanoate metabolism
Butanoate metabolism
Biosynthesis of unsaturated fatty acids
Metabolic pathways
Carbon metabolism
Fatty acid metabolism
Module
Malonate semialdehyde pathway, propanoyl-CoA => Acetyl-CoA
Lysine degradation, lysine => saccharopine => acetoacetyl-CoA
Fatty acid biosynthesis, elongation, mitochondria
beta-Oxidation
Brite
KEGG Orthology (KO) [BR:ecb00001]
 Metabolism
  Overview
   01200 Carbon metabolism
    100071381 (HADHA)
   01212 Fatty acid metabolism
    100071381 (HADHA)
  Carbohydrate metabolism
   00640 Propanoate metabolism
    100071381 (HADHA)
   00650 Butanoate metabolism
    100071381 (HADHA)
  Lipid metabolism
   00062 Fatty acid elongation
    100071381 (HADHA)
   00071 Fatty acid degradation
    100071381 (HADHA)
   01040 Biosynthesis of unsaturated fatty acids
    100071381 (HADHA)
  Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    100071381 (HADHA)
   00310 Lysine degradation
    100071381 (HADHA)
   00380 Tryptophan metabolism
    100071381 (HADHA)
  Metabolism of other amino acids
   00410 beta-Alanine metabolism
    100071381 (HADHA)
Enzymes [BR:ecb01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.211  long-chain-3-hydroxyacyl-CoA dehydrogenase
     100071381 (HADHA)
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.17  enoyl-CoA hydratase
     100071381 (HADHA)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
Ensembl: 
UniProt: 
Position
15
AA seq 762 aa AA seqDB search
MASRAIGSFRRFPASKTLRCPGYICRNFAGSSALLTRTHINYGVKGDVAVVRINSPNSKV
NTLNKELQSEFVEVMNEIWASDQIRSAVLISSKPGCFIAGADINMLAACKTNQEVTQISQ
EGQRIFEKLEKSPKPIVAAISGSCLGGGLELAISCQYRIATKDKKTVLGSPEVLLGILPG
AGGTQRLPKMVGVPAAFDMMLTGRNIHADRAKKMGLVDQLVEPLGPGLKPPEERTIEYLE
EVAVTFAKGLADKKISPKRDKGLVDKLTSVAMGIPFVRQQIYKKVEEKVRKQTKGLYPAP
LKIIDVVKTGIEQGSDAGYLSESQKFGELAMTKESKALIGLYHGQVLCKKNKFGAPQKEV
KHLAILGAGLMGAGIAQVSVDKGLKTILKDATLAGLGRGQQQVFKGLNDKVKKKALTSFE
RDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHCVFASNTSALPI
NEISAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSKDTTASAVAVGLKQGKVIIVVKD
GPGFYTTRCLAPMMSEVIRILQEGVDPKKLDSLTTSFGFPVGAATLVDEVGVDVARHVAE
DLGKAFGERFGGGSLDLLKQMVSKGFLGRKSGKGFYIYQEGVKSKNLNSDMDSILASLKI
PPKSEVSSDEDIQYRLVTRFVNEAVMCLQEGILATPAEGDIGAVFGLGFPPCLGGPFRFV
DLYGAQKIVDRLRKYEAAYGKQFTPCQLLVDHANSPNKKFYQ
NT seq 2289 nt NT seq  +upstreamnt  +downstreamnt
atggcttcgcgggctattggcagcttcaggcgcttccctgcgtccaagacgctccgctgc
ccaggttatatttgccgcaactttgcagggtcctctgctttgctgaccagaacccatatt
aactatggagtcaaaggggatgtggcagttgttcgaattaactcacccaattcaaaggta
aatacactgaataaggaactgcaatcagagttcgtagaagtcatgaatgaaatctgggcc
agcgatcaaatcagaagtgccgtccttatctcatcaaagccaggctgttttattgcaggt
gctgatatcaacatgttagctgcttgcaagaccaatcaagaggtaacgcaaatatcccag
gaaggacagagaatctttgagaaacttgagaagtccccaaagcctattgtggcggccatc
agtggatcctgcctaggaggaggacttgagcttgccatttcatgccaatacagaatagca
acaaaagataaaaaaacagtgttaggttcccctgaagttttgctggggatcttaccagga
gcaggaggcacacaaaggctgcccaaaatggtgggagtgcctgctgctttcgacatgatg
ctgactggtagaaacattcatgcagacagagcaaagaaaatgggactggttgaccaattg
gtggaacccctgggaccaggattaaagcctccagaggaacggacaattgaatacctagaa
gaagttgcagttacttttgccaaaggactagctgataagaaaatctctccgaagagagac
aaaggattggtggacaaattgacatcggtcgccatgggtattccatttgtcaggcaacag
atttacaaaaaggtggaagaaaaagtacgaaagcagaccaaaggcctttatcctgcacct
ctgaaaataattgatgtcgtaaagactggaatcgagcaagggagtgatgctggctatctc
tctgaatctcagaaattcggagagcttgcaatgaccaaagaatccaaggccttgatagga
ctttaccatggtcaggtcctgtgcaagaagaataaatttggagctccgcaaaaggaggtt
aagcacttagccattcttggtgcagggctgatgggagccggcattgcccaagtctctgtg
gataagggcctgaagactatacttaaagatgctaccctagccgggctgggccgaggacag
caacaagtgttcaaaggattgaatgataaagtgaagaagaaagctctaacatcatttgaa
agggactccattttcagcaacttgactgggcagcttgattaccagggttttgaaaaggcc
gacatggtgattgaagctgtttttgaggaccttagtcttaagcacagagtgctaaaggaa
gtagaggcggtgattccagatcactgtgtctttgccagtaacacatctgctctcccaatc
aatgaaatttctgctgtcagcaaaagacctgagaaggtgattggcatgcactacttctcc
cctgtggacaagatgcagctgctggagatcatcacaaccgagaaaacttctaaggacacg
accgcttctgctgtagcagttggcctcaagcaggggaaggtcatcattgtggttaaggat
ggacctggcttctataccaccaggtgtctcgcccccatgatgtctgaagtcatcagaatt
ctccaggaaggagttgaccctaagaagctggattcccttaccacgagctttggcttccct
gtgggcgctgccacactggtggatgaagttggagtagatgtagcaagacacgtagcagaa
gatctgggcaaagcctttggggagcggtttggaggtggaagccttgacctgctgaagcag
atggtgtccaagggcttcctgggtcgcaagtctgggaagggcttttacatctaccaggag
ggcgtgaagagtaagaatttgaattctgacatggatagtatcttggcaagcctgaagata
cctcctaagtctgaggtctcctctgatgaagacattcagtaccgcctggtgacaagattt
gtgaatgaggccgtcatgtgcctgcaggaagggatcttggctacgcctgcagagggagac
atcggagcggtctttgggctcggcttcccaccctgtctaggagggcccttccgctttgtg
gatctgtacggtgctcagaagatagtggaccggctcaggaagtatgaggctgcctatgga
aaacagttcaccccgtgccagctgctagttgaccacgctaacagccctaacaagaagttc
taccagtga

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