KEGG   Equus caballus (horse): 100072399
Entry
100072399         CDS       T01058                                 
Symbol
REV3L
Name
(RefSeq) DNA polymerase zeta catalytic subunit isoform X1
  KO
K02350  DNA polymerase zeta [EC:2.7.7.7]
Organism
ecb  Equus caballus (horse)
Pathway
ecb01524  Platinum drug resistance
ecb03460  Fanconi anemia pathway
Brite
KEGG Orthology (KO) [BR:ecb00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03460 Fanconi anemia pathway
    100072399 (REV3L)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    100072399 (REV3L)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:ecb03400]
    100072399 (REV3L)
Enzymes [BR:ecb01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.7  Nucleotidyltransferases
    2.7.7.7  DNA-directed DNA polymerase
     100072399 (REV3L)
DNA repair and recombination proteins [BR:ecb03400]
 Eukaryotic type
  TLS (translesion DNA synthesis) factors
   B-family DNA polymerases
    100072399 (REV3L)
SSDB
Motif
Pfam: DUF4683 DNA_pol_B DNA_pol_B_exo1 zf-C4pol
Other DBs
NCBI-GeneID: 100072399
NCBI-ProteinID: XP_023506702
Ensembl: ENSECAG00000022502
VGNC: 22314
Position
10:complement(61799044..61975553)
AA seq 3130 aa
MFSVRIVTADYYMASPLQGLDICQSPVTQAPVKKVPVVRVFGATPAGQKTCLHLHGIFPY
LYVPYDGYGQQPESYLSQMAFSIDRALNVALGNPSSTAQHVFKVSLVSGMPFYGYHEKER
HFMKIYLYNPAMVKRICELLQSGAIMNRYYQPHEAHIPYLLQLFIDYNLYGMNLINLAAV
KFRKARRKSNPLHPTGSCKDRLPGNSLTGTLFRWEENEIPSSLILEGVEPQSTCELEVDA
VAADILNRLDIEAQIGGNPGLQAIWEDEKQRRRNRNETSQISQPESQDRRFVPATENEKK
FQKRLQEILKQNDFSVRTLSGSVDYSDGSQEFSAELTLHPEVLSPEILQCTPANMVEVHK
DTELSKGHTRHKVEEALINEEAILNLMENSQTFQPLAQRLSESPVFLDSSPDEALVRLLA
GLENDGYQGERNRMPSQCHSFGNTKNLQNSDDEENEPQIEKEEMELSLVMSQRWDSNIEE
HCAKKRSPCRNTHRSSTEEDDSSSDEEMEWSNNNLLLGNLSIPQLDGTADENSDNPLNNE
NSRTHSSVIATSKLSVKPSIFHKDAATLEPPSSAKITFQCKHSSALSSHVLNKEDLIEDL
SQPNNTEKDLDRSVASFTNESTYSMKYPGSLSSTVHSENSHKESSKKDIVQVSSCESSIF
DYEEEIPSVTRQVPSRKYTNIRKIDKDAPFIHMNRHTCESTLGKNSFNFSDLSHSKNKLS
SEGNEKGNSTALNSLFPSSLTENCELLSCSGENRTMVQSLDSIADESGLNKLKIRYEEFQ
EHKTEKPSLSQQAAHYMFFPSVVLSNCLSRPQKLAPVTYKLQPGNKQSRLKMSKKKLVGH
QETSSKTSETGSTKDNCMQNNTCNSNSEKDNVLASDLIKVTRGAFENKTPTDSFVDCHFG
DGSLETEQSFGLYGNKYTLRAKRKVNYETEDSESSFVTHNSKVSLPHPMEIGESLDGTLK
SRKRRKMSKKLPPVIIKYIIINRFRGRKNMLVKLGKIDSKEKQVILTEEKMELYKKLAPL
KDFWPKVPDSPATKYPIYPLTPKKSHRRKSKHKSTKKKPGKQQRTNSENVKRTLSFRKRR
SHAILSPPSPSYNAETEDCDLNYSDVMSKLGFLSERSTSPINSSPPRCWSPTDPRAEEIM
AAADKEAMLLKGLNAYNSKTVNSRMEKNSRARTQVKKSKTKLVNPSVVTKKRNKRNQTSK
LVGDGKKKPRAKQKQKTNEKGTSRKHITLKDEKIKSQSGAEVKFVLKHQNVSETSNSSGG
SQLLFKQKDVSLMGSAIDHPLSAPLPTGIRAQQNLSGCFSSFLESKKPVDLQTFPSSRDD
LHSSVVCSSMGPGISKINVQRSHNQSAMFTLKESTLIQKNIFDLSNHLSQVAQNTQISSG
IMSPKTEENANTQKNCLSSIGKLNDYHNSLESKPDQTYAPNFSQCKDSQQQIVCMAEQSK
HSETCSPGNAASEESQMPNNCFVTSLKSPIKQIAWEQKQRGFILGVSNFKPERVKQRSLS
EAISQTKALSQCKNRNVSTPSAFGEGQSGLAVLKELLQKRQQKAQNANTMQDPLSTKHQP
NKNISGSLEHNKTIKRTRSVTSQRKPRTPRSTKPKEKVPKLLKVDSLNLQNSGQLDNSLS
DDSPIFFSDPGFESCYSLEDSLSPEHNYNFDINTIGQTGFCSFYSGSQFVPADLNLPQKF
LSDAVQDLFPGQTIEKTEFLSHDNQKCDEDKHHASDSTSWIRSSTLSPELFEKSSIDSNE
NHCHNQWKSSFHPLTTRSNSIMDSFCVQQAEDCLNEKSRLNRSSVSKEVFLSLSQPCNSD
WIQGHTRKEIGQALDSVNTSFTTILSSPDGELVDVASEDLELYVSRNNDILTPTPDSSPR
STSSPSQSKNGTFTPRTAHILKPLMSPPSREEIMATLLDHDLSETVYQEPFCSNPSDVPE
KPREIGGRLLMVETRLPNDLAEFEGDFSLEGLRLWKTAFSAMTQNPRPGSPLRNAQAIVN
KGSSNSHKMVEDKKIVIMPCKCAPSRQLVQSWLQAKEEYERSKKLSKIEPTGVIKSAENF
SSSVNPDDKPVVPPKMDTIPHIPPTTSHTKEDVDNSQLALQAPTTGCSQTASESQTLPPV
AASNDPEEDDDDCYVSYSSPDSPLIPPWQQAISPDFKTLNGDGRSSSPVEELRSLALENL
LKPVKGDVQKSPCSEPREPLVISPINIRTRTGMCESLCLHSTPIIQRKLLEKLPEATGLS
PLSSEPKTRKLSHKKGSNTATLRRVLLTQAKNQFTSVNTPKKETSQIDGPSLNNTYGFKV
SVQNLQEAKALHEIQNLTLISVELHARTRRDLEPDPEFDPICALFYCISSDTPLPDTDKT
ELTGVIVIDKDKTVSSQDIRYQTPLLIRSGITGLEVTYAADEKALFQEIAAIIKRYDPDI
LLGYEIQMHSWGYLLQRAAALSVNLCQMISRVPDDKIENRFAAERDEYGSDTMSEINIVG
RITLNLWRIMKNEVALTNYTFENVSFHVLHQRFPLFTFRVLSDWFDNKTDLYRWKMVDHY
ISRVRGNLQMLEQLDVIGKTSEMARLFGIQFLHVLTRGSQYRVESMMLRIAKPMNYIPVT
PSVQQRSQMRAPQCIPLIMEPESRFYSNSVLVLDFQSLYPSIVIAYNYCFSTCLGHVENL
GKYDEFKFGCTSLRVPPDLLYQIRHDITVSPNGIAFVKPSVRKGVLPRMLEEILKTRFMV
KQSMKAYKQDRALSRMLDARQLGLKLIANCTLGYTAANFSGRMPCIEVGDSIVHKARETL
EQAIKLVNDTKKWGARVVYGDTDSMFVLLKGATKEQSFKIGQEIAEAVTATNPKPVKLKF
EKVYLPCVLQTKKRYVGYMYETLDQKDPVFDAKGIETVRRDSCPAVSKILERSLKLLFET
RDISLIKQYVQRQCMKLLEGKASIQDFIFAKEYRGSFSYKPGVCVPSLELTRKMVAYDRR
SEPRVGERVPYVIIYGTPGVPLIQLVRRPVEVLQDPTLRLNATYYITKQILPPLARIFSL
IGIDVFNWYHELPRIQKATSSSRSEPGGRKSTISQYFTTLRCPVCDDLTQHGICNKCRSQ
PQHVAVILNQEIRELERKQEQLVKICKNCTGCFDRHIPCVSLNCPVLFKLSQVNRELSKA
PYLRQLLDQF
NT seq 9393 nt   +upstreamnt  +downstreamnt
atgttctcagtgcggatagtgactgccgactactacatggccagcccgctgcaggggctg
gatatctgccaatcccccgtcacccaggcccctgtcaagaaggtgccggtggtgcgagtc
ttcggagcgaccccggcaggtcagaagacgtgtcttcatctacatggcatctttccttac
ctctatgtgccatatgatggttatggacagcagccagaaagctatctttctcagatggcg
ttcagtatcgacagagcacttaatgtggctttaggcaatccatcttccactgctcagcac
gtgttcaaagtgtcattagtttcaggaatgcctttttatggttatcatgagaaggagaga
cactttatgaagatctatctttacaatcctgcaatggtgaaaaggatatgtgaacttttg
caaagtggagccataatgaatagatattaccagcctcatgaagcgcatattccctacctc
ctacagctcttcattgactacaatctgtatggaatgaatttaattaatctggctgctgtc
aagttccgaaaagcaagaaggaaaagtaatccattgcatccaactggatcttgcaaggat
cggctaccaggaaattctcttactggtactttatttcggtgggaagaaaatgaaatacca
agctcattaatactggaaggtgttgaacctcagagtacatgtgaattagaagtggatgct
gtagctgctgatatcttaaatcggctggacattgaagctcaaattggtggaaaccctggt
ctacaggccatctgggaagatgaaaagcaacggcgaagaaacagaaatgaaacttctcaa
attagccaacccgaatcacaagatcgcaggtttgtgccagcaacagaaaatgaaaaaaaa
tttcagaagagacttcaggaaattctcaaacagaatgatttctctgtcagaacattatca
ggatctgtggactacagtgacggatcccaggagttctctgctgagttaacattgcaccct
gaggttctgtctcctgaaattctgcagtgtacgccagctaatatggtagaagtccataaa
gacacagagttgagcaaaggtcacactagacacaaagtggaagaagctcttattaatgaa
gaagcaattttgaaccttatggaaaatagtcagacttttcagcctttggctcaaagactg
agtgagtcaccagttttcttggacagtagtcctgatgaggctctggtacgtcttcttgct
ggtttggaaaatgatggatatcagggagaaagaaataggatgccgtcacaatgtcactcc
tttggaaacactaaaaatctccaaaatagtgatgatgaagaaaatgaaccacagattgaa
aaagaagaaatggagcttagtctggtgatgtctcagagatgggacagcaatattgaagaa
cattgtgccaaaaagagatcaccgtgcagaaatacccatagaagttcaaccgaagaagat
gattcatcttcagatgaagaaatggaatggagtaataacaatttgcttctaggcaatctt
tctatacctcagttagatggaactgcagatgaaaatagtgacaatccattgaacaacgaa
aattctagaacccactcttctgtgattgcaacaagcaagctatcagtaaaaccttccatc
tttcataaagatgctgctacgttagaacccccatcttctgctaagattacctttcagtgt
aaacactcaagtgccctttcttcccatgttctgaacaaggaagatttaattgaagacctt
tcacagccaaacaacacagaaaaagatctagatcgttcagttgcttcttttacaaatgaa
agcacttactctatgaaataccctggatctctaagcagtactgtccactcagaaaactct
cataaagaaagtagtaagaaagatatcgttcaggtatcttcctgtgaaagtagtattttt
gattatgaagaagagattccatctgttacaagacaagtaccaagtagaaagtatacaaac
attagaaaaattgataaggatgccccttttatacatatgaaccgtcacacttgcgaaagt
acattgggcaaaaattctttcaacttttctgacttaagtcattcaaaaaataaattatca
tctgaaggaaatgaaaaaggaaacagcacagctctgaatagtttattcccttcatcgtta
actgaaaattgtgaattgctgtcatgttcaggggagaacagaactatggtgcagtctctt
gatagcattgctgatgaaagtggactgaataaacttaaaattagatatgaagaatttcaa
gaacataaaacagaaaagccaagcctcagccagcaagcagcacattacatgttttttccc
agtgttgttctttctaattgtctcagtagaccacagaaactcgctcctgtcacatataaa
ctacaacctggcaataaacagtcccggttaaaaatgagtaaaaagaaacttgtaggtcat
caagaaacttctagcaaaactagtgagactggatccacaaaagataattgtatgcaaaat
aatacttgtaatagtaattctgagaaggataatgtattggccagtgatttaattaaagtc
acccgtggagcttttgaaaataaaacacctacagacagttttgtagactgtcactttgga
gatggaagcttagaaactgagcagtcctttggattgtatggaaataaatacacacttaga
gccaaacgcaaggtaaattatgagactgaagatagtgagtcaagttttgtaacacacaac
tcaaaagttagcctacctcatcccatggaaattggcgaaagtttagatggaactctcaaa
tctcgaaaacgaagaaaaatgtctaaaaagctgcctcctgtcatcataaagtatattatt
attaatagatttagagggagaaaaaatatgcttgtgaagctagggaaaatagactctaaa
gaaaagcaagtaatattaacagaggaaaaaatggaactttataaaaagcttgcacctttg
aaggatttttggccaaaagttcctgactcccctgcaaccaaatatcccatttatccacta
acaccaaagaaaagtcacagaagaaaatcaaaacataagtctactaagaaaaaacctggt
aagcaacaaaggacaaatagtgaaaatgttaaaagaactttgtctttcaggaaaagacgg
tcacatgctattctttctcctccctcaccatcttataatgctgaaaccgaagactgtgac
ttgaattatagtgatgttatgtctaaattaggttttctttctgagagaagcacaagtccc
ataaattcttctccacctcgctgctggtctcccacagatccaagagctgaagaaattatg
gctgctgcagataaggaagcaatgcttcttaagggtcttaacgcatataatagcaagact
gttaattcccgtatggaaaaaaatagtcgagcaagaacacaggttaagaaatcaaaaaca
aagcttgttaatccttctgtagttactaagaaaaggaacaaacgaaatcagacgagtaaa
ctagtaggtgatggaaaaaagaaaccaagagcaaaacagaaacaaaaaacaaatgagaaa
ggtacgtcaagaaagcacataacacttaaagatgaaaaaataaaatcccagtctggtgct
gaagttaagtttgtgctgaaacatcagaatgtgtctgagacctcaaatagttctggaggc
tctcaactactttttaaacagaaagatgtgtccctaatgggctctgctatagatcatccc
ctttctgctcccctacccactggaattcgagcacaacagaatttatctggctgcttttct
tctttcttagaaagcaagaagcctgtggatttgcaaacattccccagttcacgagatgat
ttgcattcatcagttgtttgtagttctatgggacctggaatctcaaaaattaatgttcaa
aggtctcataatcaaagtgctatgtttactctaaaggaatcaaccttgattcaaaaaaac
atatttgacctttccaaccatttgtctcaggtagcacagaatacacagatatcttctggt
ataatgtctccaaagacagaagagaatgcaaatacacaaaaaaactgtttgtcatctatc
ggaaagttaaatgactatcataattccctagagtcaaagccagatcagacgtatgcccct
aatttttcacagtgcaaagacagtcagcagcagattgtgtgcatggcagaacagtcaaag
cacagtgaaacttgttctccaggaaatgcagcttcagaggaaagccaaatgcctaataat
tgctttgtaacttccttaaaaagtccaatcaaacaaatagcatgggagcaaaaacaaagg
ggctttattttaggtgtgtcaaattttaaacctgaaagggtaaaacaaaggtcattgtca
gaagcaatttcacaaaccaaagcactttctcagtgtaaaaatcgaaatgtatcaacacct
tcagcgtttggtgaaggacagtctgggctggcagttctaaaagaactgttacagaaaaga
cagcagaaagcacaaaatgcaaatactatgcaagacccattatctactaaacatcaacca
aacaaaaatatttctggttcccttgagcataacaaaacaattaaacgaacacgatcggta
acatctcaaagaaaacctcgaactcccagaagtacaaaacctaaagaaaaagttcccaaa
cttcttaaagtagactctcttaatttacaaaactctggccagttggacaactccctatca
gatgatagtcccatctttttttcagatccaggttttgaaagttgttactcacttgaagat
agtttgtctcctgaacataattataattttgatattaatacaataggtcaaactggattt
tgtagcttttattctggaagtcagtttgtcccagctgatctgaatttgcctcagaagttc
ctaagtgatgccgttcaggatcttttcccaggacaaactatagaaaaaactgagtttttg
agtcatgataaccagaagtgtgatgaagacaaacaccatgcctcagactcaacctcatgg
attaggtccagtactctaagccctgaactgtttgagaaatcctccatagatagcaatgag
aatcattgccacaaccagtggaaaagtagctttcatcctctaacaactcggtctaattcc
atcatggattctttctgtgtccagcaggcagaggactgtctaaatgaaaaatccagattg
aataggagttcagtaagcaaagaagtgtttcttagcctttctcagccttgcaattcagac
tggattcaaggtcataccagaaaagaaataggacaggctcttgactcagtcaatacctct
tttaccacaatactatcctcacctgatggtgaacttgtggatgtagcttctgaagattta
gaattatatgtttcaagaaacaatgacatactgacaccaactcctgatagttcaccaagg
tctaccagctctccttcacagtctaaaaatggcactttcacccctcgaactgctcacatt
ctgaaaccacttatgtccccaccaagtagggaagaaattatggcaacattgttggatcat
gacctttcggaaactgtttaccaggaacctttttgcagtaatccttctgatgtaccagaa
aagcccagggagatcggcggacggcttctcatggtagaaactcgacttccaaatgatctg
gctgagtttgagggagacttttccttggaaggccttcgtctatggaaaacagcattctca
gcaatgactcagaatccaagaccagggtcaccccttcgcaatgcccaagcaattgtcaat
aaagggtcgagtaatagccataaaatggttgaagataaaaaaattgtgattatgccttgc
aaatgtgccccaagtcgacaactggttcaatcatggcttcaagccaaagaagaatatgag
cgttccaagaaactgtctaaaattgagccaactggagttataaaatctgctgagaacttc
agctcttcagttaacccagatgacaaacctgtagtgcctccaaaaatggatacaattcca
catataccccctactacatcacataccaaggaagatgttgataattctcagcttgcttta
caagcgccaaccacaggatgcagtcaaactgcaagtgaaagtcagacactgccaccagtt
gctgcttcaaatgatcctgaggaagatgatgatgactgttatgttagttatagctcccct
gattctcccctaattcccccttggcaacaagcaatatccccagatttcaaaaccttaaat
ggagatggcagatcctcatcgccagtagaggagctacgttccttggctcttgagaacttg
ttaaagccggtgaaaggtgatgtacagaaaagcccctgcagtgagcctcgggagcctcta
gtgatatctccaattaacattaggacgagaactgggatgtgtgaatcactttgccttcac
agtacaccaatcatacagagaaaacttctggaaaagcttcctgaagcaactggccttagc
cctttatcatcagaaccaaaaacgcggaaattgagtcataagaaaggaagtaatactgcc
actcttagaagagtactcttaacacaagcaaagaatcagtttacatcagtaaatacccca
aagaaagaaacttctcagattgatggaccatctttaaacaatacttatggtttcaaagtc
agcgtccaaaacttacaggaggcaaaagctttgcatgagatacaaaatcttaccctaatc
agtgtggagttacatgctcgaactaggcgagatttagaaccagatccggagtttgaccca
atctgtgctctgttctactgcatctcatctgacactccactaccggatacagacaaaaca
gaactcacaggtgtaatagtgatcgataaagacaagacagtctccagtcaagatatcaga
tatcagaccccattacttattagatctggaattacaggactagaagttacctatgctgct
gatgagaaggcactttttcaagaaattgcagctataataaagagatatgatcctgatatt
ctgctagggtacgagattcagatgcattcctggggttacctcttacagagggctgctgcc
ttaagtgtgaacttatgtcagatgatctctcgggtgccagatgacaaaattgagaacaga
tttgcagctgaaagagatgagtatggatcagatacaatgagtgagataaatattgttggc
cgaattacgctgaatctttggagaatcatgaaaaatgaggtggctctaactaactacacc
tttgaaaatgtgagctttcacgttcttcatcagcgttttcccctctttaccttccgagtc
ttatcagattggtttgataacaagacagatctatacagatggaaaatggttgatcattac
attagccgtgtccgtggaaatctccaaatgttagaacagctggacgtgattgggaaaacc
agtgaaatggctagactttttggcattcagtttttacatgtattgacaaggggctcacag
taccgtgtggaatcaatgatgttgcgtattgctaaaccaatgaactatattcctgtgaca
cctagtgtacaacaaagatcccagatgagagccccacagtgtattcccctaattatggag
cctgaatctcgcttctatagcaactctgttcttgttttggatttccagtcactgtatcct
tctattgtgattgcatacaactactgtttttccacctgccttggccatgtggagaacttg
ggcaagtatgatgagttcaaatttggctgtacctctctaagagtacctccagatttactt
taccaaattaggcatgatatcacagtgtcccccaatggaatagcttttgtcaagccttca
gtaagaaagggtgtgctaccaagaatgcttgaagaaattttgaaaaccagattcatggtg
aagcagtcgatgaaggcttataagcaagacagagccctttcacgaatgctcgatgcacgt
cagctaggacttaagcttatagcaaattgcacactcggctatacagctgctaatttctct
gggagaatgccatgcattgaggttggggatagtattgttcacaaagccagagagaccttg
gaacaagctattaaactggtgaatgataccaagaagtggggtgctagagttgtatacggt
gatactgacagtatgtttgtactactgaaaggagccactaaggagcagtcttttaagatt
ggtcaggaaattgctgaagcggtaactgctaccaaccctaaaccagtgaaattgaagttt
gaaaaggtatatttgccctgtgtcttacaaacaaaaaagaggtatgtgggttacatgtat
gaaacactggatcaaaaggacccagtatttgatgcaaaaggaatagaaacagtcagaaga
gattcctgccctgctgtttctaagatacttgagcgttctctaaagctgctatttgaaaca
agagatataagtttaattaaacagtatgttcaacgacaatgtatgaagcttctggaagga
aaggccagcatacaagattttatctttgccaaggaatacagaggaagtttctcttataaa
cctggagtttgtgtgccatcccttgaacttacaaggaaaatggttgcttatgaccggcgc
tctgagcctcgagttggggagcgagtgccatatgtcatcatttatgggacccctggagta
ccacttatccagctggtaaggcgtcctgtggaagtcctgcaggacccaaccctgagactg
aatgccacctactatatcaccaagcaaatccttccacccctggcaagaatcttctcactt
attggaattgatgttttcaactggtatcatgaattaccaaggatccagaaagccactagc
tcctctcgaagtgaacctggagggcggaaaagcactatttcacaatatttcactacctta
cgctgtcctgtgtgtgatgacctgactcagcacggcatctgtaataaatgtcggagccaa
cctcagcatgttgcagtgatcctcaaccaagagattcgagagctggaacgtaaacaggag
cagcttgtaaagatatgcaagaactgtacaggttgctttgatcgacatatcccatgtgtt
tctctgaactgcccagtacttttcaaactctcccaagtaaacagagaattatccaaggca
ccgtatctccggcagttactagaccagttttaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (39)   
   KEGG ORTHOLOGY (1)   
   RefGene (33)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (6)   
   RefSeq(pep) (6)   
DNA sequence (8)   
   RefSeq(nuc) (6)   
   GenBank (1)   
   EMBL (1)   
Protein domain (4)   
   Pfam (4)   
All databases (64)   

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