KEGG   Equus caballus (horse): 100072744Help
Entry
100072744         CDS       T01058                                 

Gene name
PRF1
Definition
perforin 1 (pore forming protein)
Orthology
K07818  
perforin 1
Organism
ecb  Equus caballus (horse)
Pathway
Natural killer cell mediated cytotoxicity
Type I diabetes mellitus
Autoimmune thyroid disease
Allograft rejection
Graft-versus-host disease
Viral myocarditis
Brite
KEGG Orthology (KO) [BR:ecb00001]
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    100072744 (PRF1)
 Human Diseases
  Immune diseases
   05320 Autoimmune thyroid disease
    100072744 (PRF1)
   05330 Allograft rejection
    100072744 (PRF1)
   05332 Graft-versus-host disease
    100072744 (PRF1)
  Cardiovascular diseases
   05416 Viral myocarditis
    100072744 (PRF1)
  Endocrine and metabolic diseases
   04940 Type I diabetes mellitus
    100072744 (PRF1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
UniProt: 
Position
1
AA seq 555 aa AA seqDB search
MAARELLLGLLLLLLPTPAPAPCHTAARSECRRKRPFVPGSWLAGEGVDVTSLRRSGSFP
VDTQHFLRPDGTCTLCRNALQQDALQRLPLALTDWRAQGSGCRRHVVRAKGSSTEAVARE
AAGSIRNDWQVGLEVTPKPSANARVTVAGSHSKAADFAAQKTYQDQYSFSSDSVECRFYS
FRLVHAPPLHPDFKRALRALPPHFNASTEPDYLRLISNYGTHFIRSMELGGRLSALTALR
TCMLALEGLTADEVADCLAVEAEVNIGGLGSSSSQYKACEEKKQQHKLGTSFHQAYRERI
SEVVGGHHSSMHDLLFANQAEPEQFSAWVASLQDRPGLVDYSLEPLHMLLESQEPRREAL
RQAVSKYLRDKARWRDCSRPCPPGQQKSPHDPCQCVCHGSAVTSHDCCPRRRGMARLEVM
SFLARDLWGDMFTATDAYVKVFFGGQELRTGTVWDDNNPRWETRLDFGDVLLATGGPLRV
QVWDTDSGWDDDLLGSCDHAPKSGSHTVMCPLNHGLLKFSYQAKCLPHLTASTCLEYAPH
GLLGEPPGNRSGAVW
NT seq 1668 nt NT seq  +upstreamnt  +downstreamnt
atggccgcccgtgagcttctccttggcctcctcctgctgctgctgcccacgccagcccct
gccccctgccacacagccgcgcgctccgagtgccggcgcaaacgccccttcgtgcccggc
tcgtggctggcgggagaaggcgtggacgtgaccagcctccggcgttcaggctccttcccg
gtggacacccagcatttcctgcggcctgatggcacctgcaccctctgtcgcaacgccctg
cagcaggacgccctccagcgcctgcccctggcgctcactgactggcgcgcccagggctca
ggctgccggcgccacgtggtcagggccaagggcagctccaccgaggctgttgcccgggaa
gcagctggcagcatccgcaacgactggcaggtgggtctagaggtgacccccaagcccagt
gccaacgcacgagtgaccgtggccggctctcactccaaggctgctgacttcgcggcccag
aaaacctaccaggaccagtacagcttcagcagcgactcagtggagtgtcgcttctacagt
tttcgcctggtgcacgctccccctctccaccctgatttcaagagggccctcagggccctt
ccaccccacttcaacgcctccaccgagcctgactacctcaggctcatctccaactacggc
acccacttcatccgctccatggagctgggcggccggctctcggccctcaccgcgctgcgt
acctgcatgctggccctagaagggctcacagccgacgaggtggcggactgcctggccgtg
gaggctgaggtcaacataggcggccttggcagctcctcgtcacaatacaaggcctgtgag
gagaagaagcagcagcacaagctggggacctccttccaccaggcctaccgggaacgcatt
tctgaagtagtcggcggccaccacagctccatgcacgacctgctcttcgcgaaccaggct
gagcccgagcagttctcggcctgggtggcctcgctgcaggacaggcccggcctggtggac
tacagcctggagcccctgcacatgctcctggagagccaggagccgcggcgcgaggcgctg
aggcaggccgtgagcaagtacctgagggacaaggcccgctggagggactgcagccggccc
tgccccccggggcagcagaagagcccccacgacccctgccagtgtgtgtgccatggctca
gcggtcaccagccacgactgctgtccccggcggaggggcatggcccggctggaggttatg
agctttctggcgagagacctgtggggagacatgttcactgccacggacgcctacgtgaaa
gtcttctttggaggccaggagctgaggaccggcacggtgtgggacgacaacaaccccagg
tgggagacgcggctggacttcggggatgtgctcctggccacgggggggccgctgagggtg
caggtctgggacacagactctggctgggacgatgacctcctcggcagctgtgaccatgct
ccgaagtctggctcacatacggtgatgtgccctctgaaccacggcctcctgaaattctcc
taccaagccaagtgcctgcctcacctgacggcgagcacctgcctggagtacgccccccac
gggctcctgggggagcctccaggaaaccggagcggggccgtgtggtga

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