KEGG T01058: 100072744

Equus caballus (horse): 100072744

Entry

100072744 CDS T01058

Gene name

PRF1

Definition

perforin 1 (pore forming protein)

Orthology

K07818

perforin 1

Organism

ecb Equus caballus (horse)

Pathway

ecb04650	Natural killer cell mediated cytotoxicity
ecb04940	Type I diabetes mellitus
ecb05320	Autoimmune thyroid disease
ecb05330	Allograft rejection
ecb05332	Graft-versus-host disease
ecb05416	Viral myocarditis

Class

Organismal Systems; Immune system; Natural killer cell mediated cytotoxicity [PATH:ecb04650]
Human Diseases; Immune diseases; Autoimmune thyroid disease [PATH:ecb05320]
Human Diseases; Immune diseases; Allograft rejection [PATH:ecb05330]
Human Diseases; Immune diseases; Graft-versus-host disease [PATH:ecb05332]
Human Diseases; Cardiovascular diseases; Viral myocarditis [PATH:ecb05416]
Human Diseases; Endocrine and metabolic diseases; Type I diabetes mellitus [PATH:ecb04940]

SSDB

Motif

Pfam:

MACPF C2

Other DBs

NCBI-GI:

NCBI-GeneID:

Ensembl:

UniProt:

Position

AA seq 555 aa
MAARELLLGLLLLLLPTPAPAPCHTAARSECRRKRPFVPGSWLAGEGVDVTSLRRSGSFP
VDTQHFLRPDGTCTLCRNALQQDALQRLPLALTDWRAQGSGCRRHVVRAKGSSTEAVARE
AAGSIRNDWQVGLEVTPKPSANARVTVAGSHSKAADFAAQKTYQDQYSFSSDSVECRFYS
FRLVHAPPLHPDFKRALRALPPHFNASTEPDYLRLISNYGTHFIRSMELGGRLSALTALR
TCMLALEGLTADEVADCLAVEAEVNIGGLGSSSSQYKACEEKKQQHKLGTSFHQAYRERI
SEVVGGHHSSMHDLLFANQAEPEQFSAWVASLQDRPGLVDYSLEPLHMLLESQEPRREAL
RQAVSKYLRDKARWRDCSRPCPPGQQKSPHDPCQCVCHGSAVTSHDCCPRRRGMARLEVM
SFLARDLWGDMFTATDAYVKVFFGGQELRTGTVWDDNNPRWETRLDFGDVLLATGGPLRV
QVWDTDSGWDDDLLGSCDHAPKSGSHTVMCPLNHGLLKFSYQAKCLPHLTASTCLEYAPH
GLLGEPPGNRSGAVW

NT seq 1668 nt +upstreamnt +downstreamnt
atggccgcccgtgagcttctccttggcctcctcctgctgctgctgcccacgccagcccct
gccccctgccacacagccgcgcgctccgagtgccggcgcaaacgccccttcgtgcccggc
tcgtggctggcgggagaaggcgtggacgtgaccagcctccggcgttcaggctccttcccg
gtggacacccagcatttcctgcggcctgatggcacctgcaccctctgtcgcaacgccctg
cagcaggacgccctccagcgcctgcccctggcgctcactgactggcgcgcccagggctca
ggctgccggcgccacgtggtcagggccaagggcagctccaccgaggctgttgcccgggaa
gcagctggcagcatccgcaacgactggcaggtgggtctagaggtgacccccaagcccagt
gccaacgcacgagtgaccgtggccggctctcactccaaggctgctgacttcgcggcccag
aaaacctaccaggaccagtacagcttcagcagcgactcagtggagtgtcgcttctacagt
tttcgcctggtgcacgctccccctctccaccctgatttcaagagggccctcagggccctt
ccaccccacttcaacgcctccaccgagcctgactacctcaggctcatctccaactacggc
acccacttcatccgctccatggagctgggcggccggctctcggccctcaccgcgctgcgt
acctgcatgctggccctagaagggctcacagccgacgaggtggcggactgcctggccgtg
gaggctgaggtcaacataggcggccttggcagctcctcgtcacaatacaaggcctgtgag
gagaagaagcagcagcacaagctggggacctccttccaccaggcctaccgggaacgcatt
tctgaagtagtcggcggccaccacagctccatgcacgacctgctcttcgcgaaccaggct
gagcccgagcagttctcggcctgggtggcctcgctgcaggacaggcccggcctggtggac
tacagcctggagcccctgcacatgctcctggagagccaggagccgcggcgcgaggcgctg
aggcaggccgtgagcaagtacctgagggacaaggcccgctggagggactgcagccggccc
tgccccccggggcagcagaagagcccccacgacccctgccagtgtgtgtgccatggctca
gcggtcaccagccacgactgctgtccccggcggaggggcatggcccggctggaggttatg
agctttctggcgagagacctgtggggagacatgttcactgccacggacgcctacgtgaaa
gtcttctttggaggccaggagctgaggaccggcacggtgtgggacgacaacaaccccagg
tgggagacgcggctggacttcggggatgtgctcctggccacgggggggccgctgagggtg
caggtctgggacacagactctggctgggacgatgacctcctcggcagctgtgaccatgct
ccgaagtctggctcacatacggtgatgtgccctctgaaccacggcctcctgaaattctcc
taccaagccaagtgcctgcctcacctgacggcgagcacctgcctggagtacgccccccac
gggctcctgggggagcctccaggaaaccggagcggggccgtgtggtga

All links

Pathway (6)   
   KEGG PATHWAY (6)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (1)   
   ENSEMBL-ECB (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (2)   
   Pfam (2)   
All databases (17)   

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