KEGG   Equus caballus (horse): 100072744Help
Entry
100072744         CDS       T01058                                 

Gene name
PRF1
Definition
(RefSeq) perforin-1
  KO
K07818  perforin 1
Organism
ecb  Equus caballus (horse)
Pathway
ecb04210  Apoptosis
ecb04650  Natural killer cell mediated cytotoxicity
ecb04940  Type I diabetes mellitus
ecb05320  Autoimmune thyroid disease
ecb05330  Allograft rejection
ecb05332  Graft-versus-host disease
ecb05416  Viral myocarditis
Brite
KEGG Orthology (KO) [BR:ecb00001]
 Cellular Processes
  Cell growth and death
   04210 Apoptosis
    100072744 (PRF1)
 Organismal Systems
  Immune system
   04650 Natural killer cell mediated cytotoxicity
    100072744 (PRF1)
 Human Diseases
  Immune diseases
   05320 Autoimmune thyroid disease
    100072744 (PRF1)
   05330 Allograft rejection
    100072744 (PRF1)
   05332 Graft-versus-host disease
    100072744 (PRF1)
  Cardiovascular diseases
   05416 Viral myocarditis
    100072744 (PRF1)
  Endocrine and metabolic diseases
   04940 Type I diabetes mellitus
    100072744 (PRF1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: MACPF C2
Motif
Other DBs
NCBI-GeneID: 100072744
NCBI-ProteinID: XP_001502826
Ensembl: ENSECAG00000012441
UniProt: F6SSE0
Position
1
AA seq 555 aa AA seqDB search
MAARELLLGLLLLLLPTPAPAPCHTAARSECRRKRPFVPGSWLAGEGVDVTSLRRSGSFP
VDTQHFLRPDGTCTLCRNALQQDALQRLPLALTDWRAQGSGCRRHVVRAKGSSTEAVARE
AAGSIRNDWQVGLEVTPKPSANARVTVAGSHSKAADFAAQKTYQDQYSFSSDSVECRFYS
FRLVHAPPLHPDFKRALRALPPHFNASTEPDYLRLISNYGTHFIRSMELGGRLSALTALR
TCMLALEGLTADEVADCLAVEAEVNIGGLGSSSSQYKACEEKKQQHKLGTSFHQAYRERI
SEVVGGHHSSMHDLLFANQAEPEQFSAWVASLQDRPGLVDYSLEPLHMLLESQEPRREAL
RQAVSKYLRDKARWRDCSRPCPPGQQKSPHDPCQCVCHGSEATSHDCCPRRRGMARLEVM
SFLARDLWGDMFTATDAYVKVFFGGQELRTGTVWDDNNPRWETRLDFGDVLLATGGPLRV
QVWDTDSGWDDDLLGSCDHAPKSGSHTVMCPLNHGLLKFSYQAKCLPHLTASTCLEYAPH
GLLGEPPGNRSGAVW
NT seq 1668 nt NT seq  +upstreamnt  +downstreamnt
atggccgcccgtgagcttctccttggcctcctcctgctgctgctgcccacgccagcccct
gccccctgccacacagccgcgcgctccgagtgccggcgcaaacgccccttcgtgcccggc
tcgtggctggcgggagaaggcgtggacgtgaccagcctccggcgttcaggctccttcccg
gtggacacccagcatttcctgcggcctgatggcacctgcaccctctgtcgcaacgccctg
cagcaggacgccctccagcgcctgcccctggcgctcactgactggcgcgcccagggctca
ggctgccggcgccacgtggtcagggccaagggcagctccaccgaggctgttgcccgggaa
gcagctggcagcatccgcaacgactggcaggtgggtctagaggtgacccccaagcccagt
gccaacgcacgagtgaccgtggccggctctcactccaaggctgctgacttcgcggcccag
aaaacctaccaggaccagtacagcttcagcagcgactcagtggagtgtcgcttctacagt
tttcgcctggtgcacgctccccctctccaccctgatttcaagagggccctcagggccctt
ccaccccacttcaacgcctccaccgagcctgactacctcaggctcatctccaactacggc
acccacttcatccgctccatggagctgggcggccggctctcggccctcaccgcgctgcgt
acctgcatgctggccctagaagggctcacagccgacgaggtggcggactgcctggccgtg
gaggctgaggtcaacataggcggccttggcagctcctcgtcacaatacaaggcctgtgag
gagaagaagcagcagcacaagctggggacctccttccaccaggcctaccgggaacgcatt
tctgaagtagtcggcggccaccacagctccatgcacgacctgctcttcgcgaaccaggct
gagcccgagcagttctcggcctgggtggcctcgctgcaggacaggcccggcctggtggac
tacagcctggagcccctgcacatgctcctggagagccaggagccgcggcgcgaggcgctg
aggcaggccgtgagcaagtacctgagggacaaggcccgctggagggactgcagccggccc
tgccccccggggcagcagaagagcccccacgacccctgccagtgtgtgtgccatggctca
gaggccaccagccacgactgctgtccccggcggaggggcatggcccggctggaggttatg
agctttctggcgagagacctgtggggagacatgttcactgccacggacgcctacgtgaaa
gtcttctttggaggccaggagctgaggaccggcacggtgtgggacgacaacaaccccagg
tgggagacgcggctggacttcggggatgtgctcctggccacgggggggcccctgagggtg
caggtctgggacacagactctggctgggacgatgacctcctcggcagctgtgaccatgct
ccgaagtctggctcacatacggtgatgtgccctctgaaccacggcctcctgaaattctcc
taccaagccaagtgcctgcctcacctgacggcgagcacctgcctggagtacgccccccac
gggctcctgggggagcctccaggaaaccggagcggggccgtgtggtga

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