KEGG   Equus caballus (horse): 100072916Help
Entry
100072916         CDS       T01058                                 

Gene name
ALOX12
Definition
(RefSeq) arachidonate 12-lipoxygenase, 12S-type
  KO
K00458  
arachidonate 12-lipoxygenase [EC:1.13.11.31]
Organism
ecb  Equus caballus (horse)
Pathway
Arachidonic acid metabolism
Metabolic pathways
Antifolate resistance
Serotonergic synapse
Inflammatory mediator regulation of TRP channels
Brite
KEGG Orthology (KO) [BR:ecb00001]
 Metabolism
  Lipid metabolism
   00590 Arachidonic acid metabolism
    100072916 (ALOX12)
 Organismal Systems
  Nervous system
   04726 Serotonergic synapse
    100072916 (ALOX12)
  Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    100072916 (ALOX12)
 Human Diseases
  Drug resistance
   01523 Antifolate resistance
    100072916 (ALOX12)
Enzymes [BR:ecb01000]
 1. Oxidoreductases
  1.13  Acting on single donors with incorporation of molecular oxygen (oxygenases)
   1.13.11  With incorporation of two atoms of oxygen
    1.13.11.31  arachidonate 12-lipoxygenase
     100072916 (ALOX12)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
Ensembl: 
Position
11
AA seq 656 aa AA seqDB search
WATGASLFSGSHNRVQLWLVGARGEAELELQLQPARGQEEEFDRDVSEDLGPLHFVKLRK
HHSLVDDAWFCDRITVQGPGACAEAAFPCYRWVQGEGVLSLPEGTARLAGDNALDMFQKH
REKELKERQQIYRWATWKEGLPLTIAAGTKDDLPPNMRFHEEKRRDFEWTMKAGALEMVL
KRVYTFLSSWDRLEDFDQIFWGQKSALAEKVHQRWQDDEFFGYQFLNGANPMLLRRSTSL
PSRLVLPTGMEELRAQLEKELENSSLFEADFILLDGIPANVIRGEKQYLAAPLIMLKMEP
NGKLLPMVIQIQPPNPSSPTPPLFLPSDPPLAWLLAKSWVRNSDFQLHQLQYHLLNTHLV
AEVIAVATMRCLPGLHPVFKLLIPHIRYTMEINTRARTQLISEGGIFDKAVSTGGGGHVQ
LVRQAMAQLTYCSLCPPDDLADRGLLGIPSALYAHDALRLWEIIARYVEGIVHLFYHRDD
TVRGDPELQAWCREITEVGLCQAQDRGFPVSFQSQNQLCHFLTMCVFTCTAQHAAINQGQ
LDWYAWVPNAPCTMRMPPPTTKEDVTMATVMGSLPDVRQACLQMTITWHLGRRQPDMVPL
GHHKEKYFSGPKAKAVLNQFQTDLENLEKEITARNEQLDLPYEYLKPSHIENSVTI
NT seq 1971 nt NT seq  +upstreamnt  +downstreamnt
tgggccaccggggcctcgctcttctccgggtcgcacaaccgcgtgcagctgtggctggtc
ggggcgcgcggggaggcggagctggagctgcagctgcagccggcgcggggccaggaggaa
gagtttgatcgagacgtttccgaggacttggggccactgcacttcgtgaagctgcgcaaa
caccactccctggtggacgacgcgtggttctgcgaccgcatcacggtgcagggccctgga
gcctgcgcggaggccgccttcccgtgttaccgctgggtgcagggcgagggcgtgctgagc
ctgcccgagggcaccgcccgcctggcaggagacaatgcattggacatgttccagaaacat
cgagagaaggaactgaaggaaagacaacagatataccgctgggccacctggaaggaaggg
ttgcccctgacaatagctgcggggactaaggatgacctacctccaaatatgagattccac
gaggagaagagacgggactttgaatggacaatgaaggcaggggctctggagatggtcctc
aaacgcgtttataccttcctgagctcctgggaccgcctagaagattttgatcagatcttc
tggggccagaagagcgccctggctgagaaggttcaccagcgctggcaggatgatgagttt
tttggttaccagttcctcaacggtgccaatcccatgctgttgagacgctccacctctctg
ccctcccggctagtgctgcccacggggatggaggagcttcgggcccagttggagaaagaa
cttgagaacagttccctgtttgaggccgacttcatccttctggatgggattccagccaat
gtgatccgaggagagaagcagtacctggctgcaccccttatcatgctaaagatggaaccc
aatgggaagctgctacccatggtcatccagatccagccacccaaccccagctccccaacc
ccaccactgttcctgccctcagatcctccacttgcctggctcctggcaaagtcctgggtc
cgaaattcagatttccaactgcaccagctccaatatcatttgctgaacactcatctggtg
gctgaggtcatcgctgtcgccaccatgaggtgcctcccagggctacaccctgtcttcaag
ctcctgatcccacacatccgctacaccatggaaattaacacccgggcaaggacccagctc
atctcagaaggtggtatatttgataaggcagtgagcacaggtggagggggccatgtgcag
ctggtccgtcaggccatggcccagctgacctactgctccctctgtcctcctgacgatctg
gctgaccgaggtctgctgggaatcccaagtgctctctatgcccacgatgctttgcggctc
tgggagatcattgcccggtacgtggaggggatcgtccacctcttctaccacagggatgac
accgtgagaggggaccctgagctgcaggcctggtgtcgggagatcactgaggtggggctc
tgccaggcccaggaccgaggtttccctgtctccttccagtcccagaatcaactctgccat
ttccttactatgtgtgtcttcacgtgcactgcccagcacgcggccatcaaccagggccag
ctggactggtatgcctgggtccctaacgccccatgcacaatgcggatgcccccacccacc
accaaggaagatgtgacaatggccacagtgatgggctcactacctgacgtccgacaggcc
tgtcttcagatgaccatcacctggcatctgggtcgccgacagccagacatggtgcctctg
gggcatcacaaagaaaagtatttctcaggtcccaaggccaaggctgtactaaaccaattc
caaacagatctggaaaacttggaaaaggagattacagcccggaatgagcaacttgacctg
ccctatgaatatctgaagcccagccacatagagaacagtgtcactatctga

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