KEGG   Equus caballus (horse): 102148787
Entry
102148787         CDS       T01058                                 
Symbol
IL6R
Name
(RefSeq) interleukin-6 receptor subunit alpha isoform X2
  KO
K05055  interleukin 6 receptor
Organism
ecb  Equus caballus (horse)
Pathway
ecb01521  EGFR tyrosine kinase inhibitor resistance
ecb04060  Cytokine-cytokine receptor interaction
ecb04061  Viral protein interaction with cytokine and cytokine receptor
ecb04066  HIF-1 signaling pathway
ecb04151  PI3K-Akt signaling pathway
ecb04630  JAK-STAT signaling pathway
ecb04640  Hematopoietic cell lineage
ecb04659  Th17 cell differentiation
ecb04932  Non-alcoholic fatty liver disease
ecb05163  Human cytomegalovirus infection
ecb05171  Coronavirus disease - COVID-19
ecb05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:ecb00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    102148787 (IL6R)
   04066 HIF-1 signaling pathway
    102148787 (IL6R)
   04151 PI3K-Akt signaling pathway
    102148787 (IL6R)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    102148787 (IL6R)
   04061 Viral protein interaction with cytokine and cytokine receptor
    102148787 (IL6R)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    102148787 (IL6R)
   04659 Th17 cell differentiation
    102148787 (IL6R)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102148787 (IL6R)
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    102148787 (IL6R)
   05163 Human cytomegalovirus infection
    102148787 (IL6R)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    102148787 (IL6R)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    102148787 (IL6R)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors [BR:ecb04050]
    102148787 (IL6R)
   04090 CD molecules [BR:ecb04090]
    102148787 (IL6R)
Cytokine receptors [BR:ecb04050]
 Interleukin receptor families
  IL6/12 receptor family
   102148787 (IL6R)
CD molecules [BR:ecb04090]
 Proteins
  102148787 (IL6R)
SSDB
Motif
Pfam: IL6Ra-bind Ig_3 ig Ig_2 fn3 I-set
Other DBs
NCBI-GeneID: 102148787
NCBI-ProteinID: XP_005610133
Ensembl: ENSECAG00000024047
VGNC: 19035
Position
5:complement(39927715..39980091)
AA seq 471 aa
MLAVCCALLTALLAAPGAALAQGGCPALEVASDVLTRLPGASVVLTCPGGEPGDNVTFHW
MLRSRVIGGPGSHRDRWTVVGRRLVLSSVQLSDSGNYSCYQDGRLVGTVCLLVDVPPEQP
QLSCSRKSPLSNVGCEWSPQRPPSPTTKAVLLVKKFQNSPVENFQEPCLYSQESQKFSCQ
LAVPEGDNSFYIVSLCVANSAGSESSRSQTFEGYGILQPDPPVNITVTAVDGNPRWLSVT
WQDPPSWNSYFYRLHFELRYRAERSKTFTMWMVKELQHHCIIRDAWRGMRHVVQLRAQEE
FGHGLWSEWSQEVMGTPWTEPRSPEVETEVSPSTQASTTNEDNENTLFKDSANATSLPVQ
DSSLTSLPTFLVAGGSLAFGTLLCIGIVLRFKRTWKLQALKEGKTGMHPPYSLGQLVPER
PKPTPVLVPLISPPVSPSSPESDNTPRHSRPDARGPQSPYDISNRDYFFPR
NT seq 1416 nt   +upstreamnt  +downstreamnt
atgctggccgtctgctgcgcgctgctgaccgccctgcttgccgcgccgggggcggctctg
gcccaagggggctgccccgcgctggaggtggcgagcgatgtgctgacccgcctgcctggg
gccagcgttgtcctgacctgcccgggcggggaaccaggagacaatgtcacctttcactgg
atgctcaggagtcgggtcatcgggggcccaggctcacaccgcgacagatggactgtcgtg
ggaaggcggctggttctgagttccgtgcagctcagcgactctggaaactattcgtgctac
caggacggccgcctagttggaactgtgtgtttgctggtggatgttcctcccgagcagccc
cagctctcctgctcacggaagagccccctcagcaatgttggctgtgagtggagtcctcag
aggcccccctccccgacgaccaaggccgtgttactggtgaagaagtttcagaacagtcca
gtggaaaacttccaggagccgtgcctgtattctcaggagtcccagaagttctcctgccag
ttggccgtcccagagggagacaactctttctacatagtgtccctgtgcgtcgccaacagc
gctgggagcgagtccagcagatcccaaacatttgagggttacggaatcttgcaacccgat
ccacctgtcaacatcacggtcaccgctgtggacggaaacccccgctggctcagtgtcacc
tggcaagaccccccctcctggaactcatatttctacaggctacattttgagctccgatac
cgggctgaacggtcaaagacattcacaatgtggatggtcaaggagctccagcatcactgc
atcatccgcgacgcctggagaggcatgaggcatgtggtgcagcttcgggcccaggaggag
tttgggcatggcctgtggagcgagtggagccaggaagtcatgggcaccccttggacagaa
cccaggagccctgaagttgagactgaggtgtccccgtccacacaggcatctactactaat
gaagacaatgaaaatactctgtttaaagattctgcaaatgcaacaagcctcccagtgcaa
gattcttctttgacatcactgcccacattcctggtggctggaggaagcctggcctttgga
acgctcctctgcattggcattgtcctgaggttcaagaggacgtggaagctgcaggctctg
aaagaaggcaagacgggcatgcatccgccgtattccttgggacagctggtccctgagagg
cccaagcccaccccagtgcttgttcccctcatctccccgccagtgtcccccagcagcccc
gagtctgacaacaccccgaggcacagccgaccagatgccaggggcccacagagcccctat
gacatcagcaacagagactacttcttccccagatag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (12)   
   KEGG PATHWAY (12)   
Genome (1)   
   KEGG GENOME (1)   
Gene (21)   
   KEGG ORTHOLOGY (1)   
   RefGene (15)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (2)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (6)   
   Pfam (6)   
All databases (47)   

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