KEGG   Equus caballus (horse): 791242
Entry
791242            CDS       T01058                                 
Symbol
ATP2A2
Name
(RefSeq) sarcoplasmic/endoplasmic reticulum calcium ATPase 2
  KO
K05853  P-type Ca2+ transporter type 2A [EC:7.2.2.10]
Organism
ecb  Equus caballus (horse)
Pathway
ecb04020  Calcium signaling pathway
ecb04022  cGMP-PKG signaling pathway
ecb04024  cAMP signaling pathway
ecb04148  Efferocytosis
ecb04260  Cardiac muscle contraction
ecb04261  Adrenergic signaling in cardiomyocytes
ecb04380  Osteoclast differentiation
ecb04919  Thyroid hormone signaling pathway
ecb04972  Pancreatic secretion
ecb05010  Alzheimer disease
ecb05017  Spinocerebellar ataxia
ecb05022  Pathways of neurodegeneration - multiple diseases
ecb05410  Hypertrophic cardiomyopathy
ecb05412  Arrhythmogenic right ventricular cardiomyopathy
ecb05414  Dilated cardiomyopathy
ecb05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ecb00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    791242 (ATP2A2)
   04024 cAMP signaling pathway
    791242 (ATP2A2)
   04022 cGMP-PKG signaling pathway
    791242 (ATP2A2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    791242 (ATP2A2)
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    791242 (ATP2A2)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    791242 (ATP2A2)
   04261 Adrenergic signaling in cardiomyocytes
    791242 (ATP2A2)
  09154 Digestive system
   04972 Pancreatic secretion
    791242 (ATP2A2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    791242 (ATP2A2)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    791242 (ATP2A2)
   05017 Spinocerebellar ataxia
    791242 (ATP2A2)
   05022 Pathways of neurodegeneration - multiple diseases
    791242 (ATP2A2)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    791242 (ATP2A2)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    791242 (ATP2A2)
   05414 Dilated cardiomyopathy
    791242 (ATP2A2)
   05415 Diabetic cardiomyopathy
    791242 (ATP2A2)
Enzymes [BR:ecb01000]
 7. Translocases
  7.2  Catalysing the translocation of inorganic cations
   7.2.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.2.2.10  P-type Ca2+ transporter
     791242 (ATP2A2)
SSDB
Motif
Pfam: E1-E2_ATPase Cation_ATPase_C Cation_ATPase Cation_ATPase_N Hydrolase Hydrolase_3 HAD
Other DBs
NCBI-GeneID: 791242
NCBI-ProteinID: NP_001075234
Ensembl: ENSECAG00000007671
VGNC: 15651
UniProt: Q257U4
Position
8:complement(23945521..24004860)
AA seq 1042 aa
MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL
LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK
EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL
TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV
ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCRMFILDKVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVKCHQYDGLVELATICALC
NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK
KEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMIPGV
KQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMNLEDSANFIKYETNLTFVGCVGMLD
PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFRQDEDVTSKAFTGREFDEL
SPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKSEIGIAMG
SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL
GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG
CYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAVFESPYPMTMAL
SVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP
LNLTQWLMVLKISLPVILMDETLKFVARNYLEPGKECVQPATKSCSFSACTDGISWPFVL
LIMPLVIWVYSTDTNFSDMFWS
NT seq 3129 nt   +upstreamnt  +downstreamnt
atggagaacgcgcacacaaagacggtggaggaggtgctgggccacttcggcgtcaacgag
agcacggggctgagcctggagcaggtcaagaagctcaaggagagatggggctccaacgag
ttaccggctgaagaagggaaaaccttgctggaacttgtgattgagcagtttgaagactta
ctagttagaattttattgctggcagcatgtatatcttttgttttggcttggtttgaagaa
ggtgaagaaacaattacagcctttgtagaaccctttgtaattttacttatattagtagca
aatgcaattgtgggtgtatggcaggaaagaaatgctgaaaatgcaatcgaagcccttaag
gagtatgagcctgaaatgggcaaggtatatcgacaggacagaaagagtgtacagcggatt
aaagctaaggacatagttcctggtgatattgtagaaattgctgttggtgacaaagttcct
gctgatataagattaacttccatcaaatctactactctaagagttgaccagtcaattctc
acaggtgaatctgtctctgtcatcaagcacactgaccctgtccctgacccacgggctgtc
aaccaagataagaagaacatgctcttttctggcacaaacattgctgctggcaaagctatg
ggagtggttgtggcaactggagttaacactgaaattggcaagatccgggatgaaatggtg
gcaacggaacaggagagaacacctctccagcagaaactagatgagtttggggaacagctt
tccaaagtcatctcccttatttgcattgcagtctggatcataaacattgggcacttcaat
gacccagttcatggaggctcctggatcagaggtgctatttactactttaaaattgcagtg
gccctggctgtagcagccattcctgaaggtctacctgctgtcatcaccacctgcctggct
cttggaactcgcagaatggcaaagaaaaatgccattgttcgaagcctcccctcagtagaa
acccttggttgtacttctgttatctgctcagacaagactggtacacttacaacaaaccag
atgtcagtctgcaggatgttcattctggacaaagttgaaggtgatacttgttcccttaac
gagtttaccataactggatcaacatatgcacctattggagaagtgcataaagatgataaa
ccagtgaaatgtcatcaatatgatggtcttgtagaattggcaacaatttgtgctctttgt
aatgactctgctttggattacaatgaggcaaagggtgtatatgaaaaagttggagaagct
acagagacggctctcacttgcctggtagagaagatgaatgtatttgataccgaattgaaa
ggtctttctaaaatagaacgagcaaatgcctgcaactcggtcattaaacagttaatgaaa
aaagaatttactctagagttttcacgtgatagaaaatcaatgtcagtttattgtacacca
aacaaaccgagccggacatcgatgagcaaaatgtttgtgaagggtgctcccgaaggtgtc
atcgataggtgcacccacattcgagttggaagtactaaagttcctatgatccctggagtc
aaacagaagatcatgtctgttattcgggaatgggggagtggcagcgacacactgcgatgc
ctggctctggccactcatgacaacccactgagaagagaagaaatgaacctggaggactct
gccaactttattaaatatgagaccaatctgactttcgttggctgtgtgggcatgctggac
cctccaagaattgaagtggcctcttctgtgaagctgtgccggcaagcaggcatccgggtc
atcatgatcacgggggacaacaagggcaccgctgtggccatctgtcgccgcattggcatc
ttcaggcaggacgaggatgtgacgtcaaaggcttttacaggtcgggagtttgatgagctc
agtccttcagcccagagagatgcctgcttgaatgcccgctgttttgctcgagttgaacct
tcccacaagtctaaaattgtagagtttcttcagtcttttgatgagattacagctatgact
ggggatggtgtgaatgatgctcctgccctgaagaaatccgagatcggcattgccatgggc
tctggcactgcagtggctaaaaccgcctccgagatggtgctggccgacgacaacttctcc
accatcgtggctgcggtggaggagggccgggccatctacaacaacatgaagcagttcatc
cgctacctcatctcctccaacgtgggcgaggtggtctgtattttcctgacagcagccctt
ggatttcctgaggctttaattcctgtccagctgctctgggtcaatctggtgacagatggc
ctgcctgccacggcgctggggttcaaccctcctgatctagacatcatgaacaaaccaccc
cggaacccgaaggaaccactgatcagtgggtggctctttttccgttacctggctattggc
tgttacgtcggcgctgctactgtgggtgctgctgcatggtggttcattgctgctgacggt
ggtccaagagtgtccttctaccagctgagtcatttcctacagtgtaaagaggacaaccca
gactttgaaggagtggattgtgcagtctttgaatccccgtacccgatgacaatggcactc
tctgttctagtaaccatagagatgtgtaatgccctcaacagcttgtctgaaaaccagtcc
ctgctgaggatgcccccttgggagaatatctggcttgtgggctccatctgcctgtccatg
tcgctccacttcttaatcctctatgtggaacccttgcctcttatcttccagatcacaccg
ctgaatttgacccagtggctgatggtgctgaaaatctccttgcctgtgattctaatggat
gagacgctcaagtttgtggcccgcaactacttggaacctggtaaagagtgtgtgcagcct
gccaccaaatcctgctcgttctcggcatgcaccgatgggatttcctggccgtttgtgcta
ctcataatgcccctggtgatctgggtctatagcacagacactaactttagtgacatgttt
tggtcttga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (16)   
   KEGG PATHWAY (16)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (10)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (8)   
   RefSeq(nuc) (2)   
   GenBank (3)   
   EMBL (3)   
Protein domain (7)   
   Pfam (7)   
All databases (48)   

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