KEGG   Escherichia coli O6 K2 H1 CFT073 (UPEC): c0058Help
Entry
c0058             CDS       T00106                                 

Gene name
folA
Definition
dihydrofolate reductase (EC:1.5.1.3)
Orthology
K00287  
dihydrofolate reductase [EC:1.5.1.3]
Organism
ecc  Escherichia coli O6:K2:H1 CFT073 (UPEC)
Pathway
One carbon pool by folate
Folate biosynthesis
Metabolic pathways
Module
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:ecc00001]
 Metabolism
  Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    c0058 (folA)
   00670 One carbon pool by folate
    c0058 (folA)
Enzymes [BR:ecc01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     c0058 (folA)
BRITE hierarchy
SSDB OrthologParalogGene clusterGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
UniProt: 
Structure
PDB: 

Jmol
Position
52319..52933
Genome map
AA seq 204 aa AA seqDB search
MRRVQGESVDSPAEYKIFLNIILAPVDDGLRFTYSGDNFFYREISMISLIAALAVDRVIG
MENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWV
KSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWES
VFSEFHDADAQNSHSYCFEILERR
NT seq 615 nt NT seq  +upstreamnt  +downstreamnt
atgcggcgagtccagggagagagcgtggactcgccagcagaatataaaattttcctcaac
atcatcctcgcaccagtcgacgacggtttacgctttacgtatagtggcgacaattttttt
tatcgggaaatctcaatgatcagtctgattgcggcgttagcggtagatcgcgttatcggc
atggaaaacgccatgccgtggaacctgcctgccgatctcgcctggtttaaacgcaacact
ttaaataaacccgtgattatgggccgccatacctgggaatccatcggtcgtccgttgcca
ggacgcaaaaatattatcctcagcagtcaaccgggtacggacgatcgcgtaacgtgggtg
aagtcggtggatgaagccattgcggcgtgtggtgacgtaccagaaatcatggtgattggc
ggcggtcgcgtttatgagcagttcctgccgaaagcgcaaaaactgtatctgacgcatatc
gacgcggaagtggaaggcgacacccatttcccggattacgagccggatgactgggaatcg
gtattcagcgaattccacgatgccgatgcgcagaactctcacagctattgctttgagatt
ctggagcggcggtaa

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