KEGG T00106: c4696

Escherichia coli O6 K2 H1 CFT073 (UPEC): c4696

Entry

c4696             CDS       T00106

Symbol

ilvC

Name

(GenBank) Ketol-acid reductoisomerase

K00053

ketol-acid reductoisomerase [EC:1.1.1.86]

Organism

ecc Escherichia coli O6:K2:H1 CFT073 (UPEC)

Pathway

ecc00290

Valine, leucine and isoleucine biosynthesis

ecc00770

Pantothenate and CoA biosynthesis

ecc01100

Metabolic pathways

ecc01110

Biosynthesis of secondary metabolites

ecc01210

2-Oxocarboxylic acid metabolism

ecc01230

Biosynthesis of amino acids

Module

ecc_M00019

Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine

ecc_M00570

Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine

Brite

KEGG Orthology (KO) [BR:ecc00001]
09100 Metabolism
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    c4696 (ilvC)
  09108 Metabolism of cofactors and vitamins
   00770 Pantothenate and CoA biosynthesis
    c4696 (ilvC)
Enzymes [BR:ecc01000]
1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.86  ketol-acid reductoisomerase (NADP+)
     c4696 (ilvC)

SSDB

Motif

Pfam:

IlvN IlvC 2-Hacid_dh_C NAD_binding_7 ApbA AdoHcyase_NAD Sacchrp_dh_NADP

Other DBs

NCBI-ProteinID:

AAN83128

UniProt:

Q8FBR2

Position

4458802..4460427

AA seq 541 aa
MAQPLMLTLQKLQCDVVNISISAINFLSYSEFNLANANRTIRSTTSRGITMANYFNTLNL
RQQLAQLGKCRFMGRDEFADGASYLQGKKVVIVGCGAQGLNQGLNMRDSGLDISYALRKE
AIAEKRASWRKATENGFKVGTYEELIPQADLVVNLTPDKQHSDVVRTVQPLMKDGAALGY
SHGFNIVEVGEQIRKDITVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPKGEGMAI
AKAWAAATGGHRAGVLESSFVAEVKSDLMGEQTILCGMLQAGSLLCFDKLVEEGTDPAYA
EKLIQFGWETITEALKQGGITLMMDRLSNPAKLRAYALSEQLKEIMAPLFQKHMDDIISG
EFSSGMMADWANDDKKLLTWREETGKTAFETAPQYEGKIGEQEYFDKGVLMIAMVKAGVE
LAFETMVDSGIIEESAYYESLHELPLIANTIARKRLYEMNVVISDTAEYGNYLFSYACVP
LLKPFMAELQPGDLGKAIPEGAVDNAQLRDVNEAIRSHAIEQVGKKLRGYMTDMKRIAVA
G

NT seq 1626 nt +upstreamnt +downstreamnt
atggcgcagcccttaatgttgacgttgcagaaattgcaatgtgacgttgtgaatatatca
atttccgcaataaatttcctgtcatatagtgaattcaatctcgcaaacgcgaaccgaaca
ataagaagcacaacatcacgaggaatcaccatggctaactacttcaatacactgaatctg
cgccagcagttggcacagctgggcaaatgtcgctttatggggcgcgatgaattcgccgat
ggcgcgagctaccttcagggtaaaaaagtagtcatcgtcggctgtggcgcacagggtctg
aaccagggcctgaacatgcgtgattctggtctcgatatctcctacgctctgcgtaaagaa
gcgattgctgagaagcgcgcatcctggcgtaaagcaaccgaaaatggttttaaagtgggt
acttacgaagaactgatcccgcaggcggatctggtggttaacctgacgccggacaagcag
cactctgatgtagtgcgcaccgtacagccactgatgaaagacggcgcggcgctgggctac
tctcatggtttcaatatcgtagaagtgggtgagcagatccgtaaagacatcaccgtcgta
atggttgcgccgaaatgccctggcaccgaagtacgtgaagagtacaaacgtggattcggc
gtaccgacgctgattgccgttcacccggaaaacgatccgaaaggcgaaggcatggcgatc
gctaaagcatgggcggctgcaaccggcggtcaccgtgcgggcgttctggaatcctctttc
gttgcggaagtgaaatctgacctgatgggcgagcaaaccatcctgtgcggtatgttgcaa
gctggttctctgctgtgcttcgacaagctggtggaagaaggcaccgatccggcatacgca
gaaaaactgattcagttcggttgggaaaccatcaccgaagcgctgaaacagggcggcatc
accctgatgatggaccgtctttctaacccggcgaaactgcgtgcttacgcgctttctgag
caactgaaagagatcatggcgccgctgttccagaaacatatggacgacatcatctccggc
gaattctcctccggcatgatggctgactgggccaacgacgataagaaactgctgacctgg
cgtgaagagactggcaaaaccgcattcgaaaccgcgccgcagtatgaaggcaaaatcggt
gaacaggagtacttcgataaaggcgtactgatgatcgcgatggtaaaagcaggcgttgag
ttggcgtttgaaaccatggttgattccggcatcatcgaagaatctgcttactatgaatca
ctgcacgaactgccgctgattgccaacaccatcgcccgtaagcgtctgtacgaaatgaac
gtggttatctccgatactgccgagtacggtaactatctgttctcttacgcttgtgtgcca
ctgctgaaaccgtttatggcagagctgcaaccgggcgacctgggtaaagctattccggaa
ggtgcggtagataacgcgcagctgcgtgatgtaaatgaagcgattcgcagccatgcgatt
gagcaggtaggtaagaaactgcgcggctatatgacggatatgaaacgtattgctgttgcg
ggttaa

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