| Entry |
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| Gene name |
dxr
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| Definition |
(GenBank) 1-deoxy-D-xylulose-5-phosphate reductoisomerase
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| KO |
| 1-deoxy-D-xylulose-5-phosphate reductoisomerase [EC: 1.1.1.267] |
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| Organism |
eci Escherichia coli O18:K1:H7 UTI89 (UPEC)
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| Pathway |
| Terpenoid backbone biosynthesis | | Metabolic pathways | | Biosynthesis of secondary metabolites | | Biosynthesis of antibiotics |
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| Module |
| C5 isoprenoid biosynthesis, non-mevalonate pathway |
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| Brite |
KEGG Orthology (KO) [BR:eci00001]
Metabolism
Metabolism of terpenoids and polyketides
00900 Terpenoid backbone biosynthesis
UTI89_C0188 (dxr)
Enzymes [BR:eci01000]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.267 1-deoxy-D-xylulose-5-phosphate reductoisomerase
UTI89_C0188 (dxr)
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| SSDB |
    |
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| Motif |
 |
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| Other DBs |
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| Structure |
PDB: |
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| Position |
198322..199518
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| AA seq |
398 aa  
MKQLTILGSTGSIGCSTLDVVRHNPEHFRVVALVAGKNVARMVEQCLEFSPRYAVMDDEA
SAKLLKTMLQQQGSRTEVLSGQQAACDMAALEDVDQVMAAIVGAAGLLPTLAAIRAGKTI
LLANKESLVTCGRLFMDAVKQSKAQLLPVDSEHNAIFQSLPQPIQHNLGYADLEQNGVVS
ILLTGSGGPFRETPLRDLATMTPDQACRHPNWSMGRKISVDSATMMNKGLEYIEARWLFN
ASASQMEVLIHPQSVIHSMVRYQDGSVLAQLGEPDMRTPIAHTMAWPNRVNSGVKPLDFC
KLSALTFAAPDYDRYPCLKLAMEAFEQGQAATTALNAANEITVAAFLAQQIRFTDIAALN
LSVLEKMDMREPQCVDDVLSVDANAREVARKEVMRLAS |
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| NT seq |
1197 nt  +upstreamnt +downstreamnt
atgaagcaactcaccattctgggctcgaccggctcgattggttgcagcacgctggacgtg
gtgcgccataatcccgaacacttccgcgtagttgcgctggtggcaggcaaaaatgtcgct
cgcatggtagaacagtgcctggaattctctccccgctatgctgtaatggacgatgaagcg
agtgcgaaacttcttaaaacgatgctacagcaacagggtagccgcaccgaagtcttaagt
gggcaacaagccgcttgcgatatggcagcgcttgaggatgttgatcaggtgatggcagcc
attgttggcgctgctgggctgttacctacgcttgctgcgatccgcgcgggtaaaaccatt
ttgctggccaataaagaatcactggttacctgcggacgtctgtttatggacgccgtaaag
cagagcaaagcgcaattgttaccggtcgatagcgaacataacgccatttttcagagttta
ccgcaacctatccagcataatctgggatacgctgaccttgagcaaaatggcgtggtgtcc
attttacttaccgggtctggtggccctttccgtgagacgccattgcgcgatttggcaaca
atgacgcccgatcaagcctgccgtcatccgaactggtcgatgggacgtaaaatttctgtc
gattcggctaccatgatgaacaaaggtctggaatacattgaagcgcgttggctgtttaac
gccagcgccagccagatggaagtgctgattcacccgcagtcagtgattcactcaatggtg
cgctatcaggacggcagtgttctggcgcagctgggggaaccggatatgcgtacgccaatt
gcccacaccatggcatggccgaatcgcgtgaactctggcgtgaagccgctcgatttttgc
aaactaagtgcgttgacatttgccgcaccggattatgatcgttatccatgcctgaaactg
gcgatggaggcgttcgaacaaggccaggcagcgacgacagcattgaatgccgcaaacgaa
atcaccgtggctgcttttcttgcgcaacaaatccgctttacggatatcgccgcgttgaat
ttatccgtactggaaaaaatggatatgcgcgaaccacaatgtgtggatgatgtgttatct
gttgatgcgaacgcgcgtgaagtcgccagaaaagaggtgatgcgtctcgcaagctga |
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