KEGG T00672: EcSMS35

Escherichia coli SMS-3-5 (environmental): EcSMS35_0050

Entry

EcSMS35_0050 CDS T00672

Gene name

folA

Definition

dihydrofolate reductase (EC:1.5.1.3)

Orthology

K00287

dihydrofolate reductase [EC:1.5.1.3]

Organism

ecm Escherichia coli SMS-3-5 (environmental)

Pathway

ecm00670	One carbon pool by folate
ecm00790	Folate biosynthesis
ecm01100	Metabolic pathways

Module

ecm_M00126

Tetrahydrofolate biosynthesis, GTP => THF

Class

Metabolism; Metabolism of cofactors and vitamins; Folate biosynthesis [PATH:ecm00790]
Metabolism; Metabolism of cofactors and vitamins; One carbon pool by folate [PATH:ecm00670]

SSDB

Motif

Pfam:

DHFR_1

Other DBs

NCBI-GI:

170680741

NCBI-GeneID:

6144196

UniProt:

B1LFY2

Structure

PDB:

3DAU 1RA9 3QL0 1RA2 4DFR 4EJ1 3QYL 3OCH 3QL3 1RA8 1RA3 1RF7 1RX2 1DHJ 1DYJ 2D0K 1RC4 1RA1 1RX9 1JOM 1DYH 1DYI 1DHI 3DRC 2DRC 1DRA 3K74 1JOL 1DRB 1RG7 1RX1 1RX6 3KFY 3R33 3QYO 1RB2 2ANQ 4EIZ 2INQ 1RX3 1RX4 1DDS 1RB3 1RX7 1RX5 1DRH 5DFR 1RH3 6DFR 1DDR 4EIG 1TDR 7DFR 1DRE 1RD7 1RE7 2ANO 4FHB 1RX8

Position

54894..55484

AA seq 196 aa
MDSPAEYKIFLNIILAPVDDGLRFTYSGDNFFYREISMISLIAALAVDRVIGMENAMPWN
LPADLAWFKRNTLNKPVIMGRHTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIA
ACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDA
DAQNSHSYCFEILERR

NT seq 591 nt +upstreamnt +downstreamnt
gtggactcgccagcagaatataaaattttcctcaacatcatcctcgcaccagtcgacgac
ggtttacgctttacgtatagtggcgacaattttttttatcgggaaatctcaatgatcagt
ctgattgcggcgttagcggtagatcgcgttatcggcatggaaaacgccatgccgtggaac
ctgcctgccgatctcgcctggtttaaacgcaacaccttaaataaacccgtaattatgggc
cgccatacctgggaatccatcggtcgtccgctgccaggacgcaaaaatattatcctcagc
agtcaaccgggtacggacgatcgtgtaacgtgggtgaaatcggttgatgaagccatcgcg
gcgtgtggtgacgtaccagaaatcatggtgattggcggtggtcgcgtttatgagcagttc
ctgccaaaagcgcaaaaactgtatctgacgcatattgacgcagaagtggaaggcgacacc
catttcccggattacgagccggatgactgggaatcggtattcagcgaattccacgacgct
gatgcgcagaactctcacagctattgctttgagattctggagcggcggtaa

All links

Pathway (4)   
   KEGG PATHWAY (3)   
   KEGG MODULE (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (7)   
   KEGG ENZYME (1)   
   KEGG REACTION (6)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
3D Structure (59)   
   PDB (59)   
Protein domain (1)   
   Pfam (1)   
All databases (86)   

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