KEGG E.coli: b0086

Escherichia coli K-12 MG1655: b0086

Entry

b0086 CDS E.coli

Gene name murF, ECK0087, JW0084, mra

Definition UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase
(EC:6.3.2.10)

Orthology K01929 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D
-alanyl-D-alanine ligase [EC:6.3.2.10]

Pathway eco00300 Lysine biosynthesis
eco00550 Peptidoglycan biosynthesis
eco01100 Metabolic pathways

Class Metabolism; Amino Acid Metabolism; Lysine biosynthesis
[PATH:eco00300]
Metabolism; Glycan Biosynthesis and Metabolism; Peptidoglycan
biosynthesis [PATH:eco00550]

SSDB

Motif Pfam: Mur_ligase_M Mur_ligase_C Mur_ligase

Other DBs NCBI-GI: 16128079
NCBI-GeneID: 944813
RegulonDB: B0086
EcoGene: EG10622
ECOCYC: EG10622
UniProt: P11880

Structure

PDB: 1GG4

Position 94650..96008

AA seq 452 aa
MISVTLSQLTDILNGELQGADITLDAVTTDTRKLTPGCLFVALKGERFDAHDFADQAKAG
GAGALLVSRPLDIDLPQLIVKDTRLAFGELAAWVRQQVPARVVALTGSSGKTSVKEMTAA
ILSQCGNTLYTAGNLNNDIGVPMTLLRLTPEYDYAVIELGANHQGEIAWTVSLTRPEAAL
VNNLAAAHLEGFGSLAGVAKAKGEIFSGLPENGIAIMNADNNDWLNWQSVIGSRKVWRFS
PNAANSDFTATNIHVTSHGTEFTLQTPTGSVDVLLPLPGRHNIANALAAAALSMSVGATL
DAIKAGLANLKAVPGRLFPIQLAENQLLLDDSYNANVGSMTAAVQVLAEMPGYRVLVVGD
MAELGAESEACHVQVGEAAKAAGIDRVLSVGKQSHAISTASGVGEHFADKTALITRLKLL
IAEQQVITILVKGSRSAAMEEVVRALQENGTC

NT seq 1359 nt +upstreamnt +downstreamnt
atgattagcgtaacccttagccaacttaccgacattctcaacggtgaactgcaaggtgca
gatatcacccttgatgctgtaaccactgatacccgaaaactgacgccgggctgcctgttt
gttgccctgaaaggcgaacgttttgatgcccacgattttgccgaccaggcgaaagctggc
ggcgcaggcgcactactggttagccgtccgctggacatcgacctgccgcagttaatcgtc
aaggatacgcgtctggcgtttggtgaactggctgcatgggttcgccagcaagttccggcg
cgcgtggttgctctgacggggtcctccggcaaaacctccgttaaagagatgacggcggcg
attttaagccagtgcggcaacacgctttatacggcaggcaatctcaacaacgacatcggt
gtaccgatgacgctgttgcgcttaacgccggaatacgattacgcagttattgaacttggc
gcgaaccatcagggcgaaatagcctggactgtgagtctgactcgcccggaagctgcgctg
gtcaacaacctggcagcggcgcatctggaaggttttggctcgcttgcgggtgtcgcgaaa
gcgaaaggtgaaatctttagcggcctgccggaaaacggtatcgccattatgaacgccgac
aacaacgactggctgaactggcagagcgtaattggctcacgcaaagtgtggcgtttctca
cccaatgccgccaacagcgatttcaccgccaccaatatccatgtgacctcgcacggtacg
gaatttaccctacaaaccccaaccggtagcgtcgatgttctgctgccgttgccggggcgt
cacaatattgcgaatgcgctggcagccgctgcgctctccatgtccgtgggcgcaacgctt
gatgctatcaaagcggggctggcaaatctgaaagctgttccaggccgtctgttccccatc
caactggcagaaaaccagttgctgctcgacgactcctacaacgccaatgtcggttcaatg
actgcagcagtccaggtactggctgaaatgccgggctaccgcgtgctggtggtgggcgat
atggcggaactgggcgctgaaagcgaagcctgccatgtacaggtgggcgaggcggcaaaa
gctgctggtattgaccgcgtgttaagcgtgggtaaacaaagccatgctatcagcaccgcc
agcggcgttggcgaacattttgctgataaaactgcgttaattacgcgtcttaaattactg
attgctgagcaacaggtaattacgattttagttaagggttcacgtagtgccgccatggaa
gaggtagtacgcgctttacaggagaatgggacatgttag

All links

Pathway (3)   
   KEGG PATHWAY (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (7)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (2)   
   ECOCYC (1)   
   ECOGENE (1)   
   REGULONDB-ECO (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (2)   
   GenBank (1)   
   EMBL (1)   
3D Structure (1)   
   PDB (1)   
Protein domain (3)   
   Pfam (3)   
All databases (20)

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