KEGG   Escherichia coli K-12 MG1655: b0116Help
Entry
b0116             CDS       T00007                                 

Gene name
lpd
Definition
(RefSeq) dihydrolipoyl dehydrogenase; E3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes; glycine cleavage system L protein; dihydrolipoamide dehydrogenase
  KO
K00382  dihydrolipoamide dehydrogenase [EC:1.8.1.4]
Organism
eco  Escherichia coli K-12 MG1655
Pathway
eco00010  Glycolysis / Gluconeogenesis
eco00020  Citrate cycle (TCA cycle)
eco00260  Glycine, serine and threonine metabolism
eco00280  Valine, leucine and isoleucine degradation
eco00620  Pyruvate metabolism
eco00630  Glyoxylate and dicarboxylate metabolism
eco00640  Propanoate metabolism
eco01100  Metabolic pathways
eco01110  Biosynthesis of secondary metabolites
eco01120  Microbial metabolism in diverse environments
eco01130  Biosynthesis of antibiotics
eco01200  Carbon metabolism
Module
eco_M00009  Citrate cycle (TCA cycle, Krebs cycle)
eco_M00011  Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
eco_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:eco00001]
 Metabolism
  Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    b0116 (lpd)
   00020 Citrate cycle (TCA cycle)
    b0116 (lpd)
   00620 Pyruvate metabolism
    b0116 (lpd)
   00630 Glyoxylate and dicarboxylate metabolism
    b0116 (lpd)
   00640 Propanoate metabolism
    b0116 (lpd)
  Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    b0116 (lpd)
   00280 Valine, leucine and isoleucine degradation
    b0116 (lpd)
Enzymes [BR:eco01000]
 1. Oxidoreductases
  1.8  Acting on a sulfur group of donors
   1.8.1  With NAD+ or NADP+ as acceptor
    1.8.1.4  dihydrolipoyl dehydrogenase
     b0116 (lpd)
Exosome [BR:eco04147]
 Exosomal proteins
  Exosomal proteins of breast cancer cells
   b0116 (lpd)
BRITE hierarchy
SSDB OrthologParalogGene clusterGFIT
Motif
Pfam: Pyr_redox_2 Pyr_redox_dim Pyr_redox FAD_oxidored GIDA Pyr_redox_3 FAD_binding_2 HI0933_like AlaDh_PNT_C Thi4 FAD_binding_3 NAD_binding_8 Lycopene_cycl FMO-like
Motif
Other DBs
NCBI-GeneID: 944854
NCBI-ProteinID: NP_414658
Pasteur: lpd
RegulonDB: ECK120000536
ECOCYC: EG10543
ASAP: ABE-0000404
UniProt: P0A9P0
Structure
PDB: 

Jmol
Position
127912..129336
Genome map
AA seq 474 aa AA seqDB search
MSTEIKTQVVVLGAGPAGYSAAFRCADLGLETVIVERYNTLGGVCLNVGCIPSKALLHVA
KVIEEAKALAEHGIVFGEPKTDIDKIRTWKEKVINQLTGGLAGMAKGRKVKVVNGLGKFT
GANTLEVEGENGKTVINFDNAIIAAGSRPIQLPFIPHEDPRIWDSTDALELKEVPERLLV
MGGGIIGLEMGTVYHALGSQIDVVEMFDQVIPAADKDIVKVFTKRISKKFNLMLETKVTA
VEAKEDGIYVTMEGKKAPAEPQRYDAVLVAIGRVPNGKNLDAGKAGVEVDDRGFIRVDKQ
LRTNVPHIFAIGDIVGQPMLAHKGVHEGHVAAEVIAGKKHYFDPKVIPSIAYTEPEVAWV
GLTEKEAKEKGISYETATFPWAASGRAIASDCADGMTKLIFDKESHRVIGGAIVGTNGGE
LLGEIGLAIEMGCDAEDIALTIHAHPTLHESVGLAAEVFEGSITDLPNPKAKKK
NT seq 1425 nt NT seq  +upstreamnt  +downstreamnt
atgagtactgaaatcaaaactcaggtcgtggtacttggggcaggccccgcaggttactcc
gctgccttccgttgcgctgatttaggtctggaaaccgtaatcgtagaacgttacaacacc
cttggcggtgtttgcctgaacgtcggctgtatcccttctaaagcactgctgcacgtagca
aaagttatcgaagaagccaaagcgctggctgaacacggtatcgtcttcggcgaaccgaaa
accgatatcgacaagattcgtacctggaaagagaaagtgatcaatcagctgaccggtggt
ctggctggtatggcgaaaggccgcaaagtcaaagtggtcaacggtctgggtaaattcacc
ggggctaacaccctggaagttgaaggtgagaacggcaaaaccgtgatcaacttcgacaac
gcgatcattgcagcgggttctcgcccgatccaactgccgtttattccgcatgaagatccg
cgtatctgggactccactgacgcgctggaactgaaagaagtaccagaacgcctgctggta
atgggtggcggtatcatcggtctggaaatgggcaccgtttaccacgcgctgggttcacag
attgacgtggttgaaatgttcgaccaggttatcccggcagctgacaaagacatcgttaaa
gtcttcaccaagcgtatcagcaagaaattcaacctgatgctggaaaccaaagttaccgcc
gttgaagcgaaagaagacggcatttatgtgacgatggaaggcaaaaaagcacccgctgaa
ccgcagcgttacgacgccgtgctggtagcgattggtcgtgtgccgaacggtaaaaacctc
gacgcaggcaaagcaggcgtggaagttgacgaccgtggtttcatccgcgttgacaaacag
ctgcgtaccaacgtaccgcacatctttgctatcggcgatatcgtcggtcaaccgatgctg
gcacacaaaggtgttcacgaaggtcacgttgccgctgaagttatcgccggtaagaaacac
tacttcgatccgaaagttatcccgtccatcgcctataccgaaccagaagttgcatgggtg
ggtctgactgagaaagaagcgaaagagaaaggcatcagctatgaaaccgccaccttcccg
tgggctgcttctggtcgtgctatcgcttccgactgcgcagacggtatgaccaagctgatt
ttcgacaaagaatctcaccgtgtgatcggtggtgcgattgtcggtactaacggcggcgag
ctgctgggtgaaatcggcctggcaatcgaaatgggttgtgatgctgaagacatcgcactg
accatccacgcgcacccgactctgcacgagtctgtgggcctggcggcagaagtgttcgaa
ggtagcattaccgacctgccgaacccgaaagcgaagaagaagtaa

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