KEGG E.coli: b0642

Escherichia coli K-12 MG1655: b0642

Entry

b0642 CDS E.coli

Gene name leuS, ECK0635, JW0637

Definition leucyl-tRNA synthetase (EC:6.1.1.4)

Orthology K01869 leucyl-tRNA synthetase [EC:6.1.1.4]

Pathway eco00290 Valine, leucine and isoleucine biosynthesis
eco00970 Aminoacyl-tRNA biosynthesis

Class Metabolism; Amino Acid Metabolism; Valine, leucine and isoleucine
biosynthesis [PATH:eco00290]
Genetic Information Processing; Translation; Aminoacyl-tRNA
biosynthesis [PATH:eco00970]

SSDB

Motif Pfam: tRNA-synt_1 tRNA-synt_1g Anticodon_1 tRNA-synt_1f tRNA-synt_1e
tRNA-synt_1d
PROSITE: AA_TRNA_LIGASE_I

Other DBs NCBI-GI: 16128625
NCBI-GeneID: 947497
RegulonDB: B0642
EcoGene: EG10532
ECOCYC: EG10532
UniProt: P07813

Structure

PDB: 2AJG 2AJH 2AJI

Position complement(671424..674006)

AA seq 860 aa
MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGD
VIARYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYD
WSRELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCPNDQTVLANEQVIDGCCWRCD
TKVERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYD
NTLTVYTTRPDTFMGCTYLAVAAGHPLAQKAAENNPELAAFIDECRNTKVAEAEMATMEK
KGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPVI
LAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIADKLTAMGVGERKVNYRLRDW
GVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILPEDVVMDGITSPIKADPEWAKTTVNG
MPALRETDTFDTFMESSWYYARYTCPQYKEGMLDSEAANYWLPVDIYIGGIEHAIMHLLY
FRFFHKLMRDAGMVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGR
IVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQE
SGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTENQKALRRDVHKTIAKVTDDIGRRQ
TFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQELKGEG
DIDNAPWPVADEKAMVEDSTLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHLVAKYLD
GVTVRKVIYVPGKLLNLVVG

NT seq 2583 nt +upstreamnt +downstreamnt
atgcaagagcaataccgcccggaagagatagaatccaaagtacagcttcattgggatgag
aagcgcacatttgaagtaaccgaagacgagagcaaagagaagtattactgcctgtctatg
cttccctatccttctggtcgactacacatgggccacgtacgtaactacaccatcggtgac
gtgatcgcccgctaccagcgtatgctgggcaaaaacgtcctgcagccgatcggctgggac
gcgtttggtctgcctgcggaaggcgcggcggtgaaaaacaacaccgctccggcaccgtgg
acgtacgacaacatcgcgtatatgaaaaaccagctcaaaatgctgggctttggttatgac
tggagccgcgagctggcaacctgtacgccggaatactaccgttgggaacagaaattcttc
accgagctgtataaaaaaggcctggtatataagaagacttctgcggtcaactggtgcccg
aacgaccagaccgtactggcgaacgaacaagttatcgacggctgctgctggcgctgcgat
accaaagttgaacgtaaagagatcccgcagtggtttatcaaaatcactgcttacgctgac
gagctgctcaacgatctggataaactggatcactggccagacaccgttaaaaccatgcag
cgtaactggatcggtcgttccgaaggcgtggagatcaccttcaacgttaacgactatgac
aacacgctgaccgtttacactacccgcccggacacctttatgggttgtacctacctggcg
gtagctgcgggtcatccgctggcgcagaaagcggcggaaaataatcctgaactggcggcc
tttattgacgaatgccgtaacaccaaagttgccgaagctgaaatggcgacgatggagaaa
aaaggcgtcgatactggctttaaagcggttcacccattaacgggcgaagaaattcccgtt
tgggcagcaaacttcgtattgatggagtacggcacgggcgcagttatggcggtaccgggg
cacgaccagcgcgactacgagtttgcctctaaatacggcctgaacatcaaaccggttatc
ctggcagctgacggctctgagccagatctttctcagcaagccctgactgaaaaaggcgtg
ctgttcaactctggcgagttcaacggtcttgaccatgaagcggccttcaacgccatcgcc
gataaactgactgcgatgggcgttggcgagcgtaaagtgaactaccgcctgcgcgactgg
ggtgtttcccgtcagcgttactggggcgcgccgattccgatggtgacgctggaagacggt
accgtaatgccgaccccggacgaccagctgccggtgatcctgccggaagatgtggtaatg
gacggcattaccagcccgattaaagcagatccggagtgggcgaaaactaccgttaacggt
atgccagcactgcgtgaaaccgacactttcgacacctttatggagtcctcctggtactat
gcgcgctacacttgcccgcagtacaaagaaggtatgctggattccgaagcggctaactac
tggctgccggtggatatctacattggtggtattgaacacgccattatgcacctgctctac
ttccgcttcttccacaaactgatgcgtgatgcaggcatggtgaactctgacgaaccagcg
aaacagttgctgtgtcagggtatggtgctggcagatgccttctactatgttggcgaaaac
ggcgaacgtaactgggtttccccggttgatgctatcgttgaacgtgacgagaaaggccgt
atcgtgaaagcgaaagatgcggcaggccatgaactggtttataccggcatgagcaaaatg
tccaagtcgaagaacaacggtatcgacccgcaggtgatggttgaacgttacggcgcggac
accgttcgtctgtttatgatgtttgcttctccggctgatatgactctcgaatggcaggaa
tccggtgtggaaggggctaaccgcttcctgaaacgtgtctggaaactggtttacgagcac
acagcaaaaggtgatgttgcggcactgaacgttgatgcgctgactgaaaatcagaaagcg
ctgcgtcgcgatgtgcataaaacgatcgctaaagtgaccgatgatatcggccgtcgtcag
accttcaacaccgcaattgcggcgattatggagctgatgaacaaactggcgaaagcacca
accgatggcgagcaggatcgcgctctgatgcaggaagcactgctggccgttgtccgtatg
cttaacccgttcaccccgcacatctgcttcacgctgtggcaggaactgaaaggcgaaggc
gatatcgacaacgcgccgtggccggttgctgacgaaaaagcgatggtggaagactccacg
ctggtcgtggtgcaggttaacggtaaagtccgtgccaaaatcaccgttccggtggacgca
acggaagaacaggttcgcgaacgtgctggccaggaacatctggtagcaaaatatcttgat
ggcgttactgtacgtaaagtgatttacgtaccaggtaaactcctcaatctggtcgttggc
taa

All links

Pathway (2)   
   KEGG PATHWAY (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (7)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (2)   
   ECOCYC (1)   
   ECOGENE (1)   
   REGULONDB-ECO (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (2)   
   GenBank (1)   
   EMBL (1)   
3D Structure (3)   
   PDB (3)   
Protein domain (7)   
   Pfam (6)   
   PROSITE (1)   
All databases (25)

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