KEGG   Escherichia coli K-12 MG1655: b0842
Entry
b0842             CDS       T00007                                 
Symbol
mdfA
Name
(RefSeq) multidrug efflux pump MdfA/Na(+):H(+) antiporter/K(+):H(+) antiporter
  KO
K08160  MFS transporter, DHA1 family, multidrug/chloramphenicol efflux transport protein
Organism
eco  Escherichia coli K-12 MG1655
Brite
KEGG Orthology (KO) [BR:eco00001]
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:eco02000]
    b0842 (mdfA)
   01504 Antimicrobial resistance genes [BR:eco01504]
    b0842 (mdfA)
Transporters [BR:eco02000]
 Major facilitator superfamily (MFS)
  Drug transporters
   Drug:H+ antiporter-1 (12 spanner) (DHA1) family [TC:2.A.1.2]
    b0842 (mdfA)
Antimicrobial resistance genes [BR:eco01504]
 Gene variants
  Macrolide resistance genes
   Transporters
    b0842 (mdfA)
SSDB
Motif
Pfam: MFS_1 Sugar_tr
Other DBs
NCBI-GeneID: 945448
NCBI-ProteinID: NP_415363
Pasteur: cmr
RegulonDB: ECK120003040
ECOCYC: G6440
ASAP: ABE-0002871
UniProt: P0AEY8
Structure
Position
883673..884905
AA seq 410 aa
MQNKLASGARLGRQALLFPLCLVLYEFSTYIGNDMIQPGMLAVVEQYQAGIDWVPTSMTA
YLAGGMFLQWLLGPLSDRIGRRPVMLAGVVWFIVTCLAILLAQNIEQFTLLRFLQGISLC
FIGAVGYAAIQESFEEAVCIKITALMANVALIAPLLGPLVGAAWIHVLPWEGMFVLFAAL
AAISFFGLQRAMPETATRIGEKLSLKELGRDYKLVLKNGRFVAGALALGFVSLPLLAWIA
QSPIIIITGEQLSSYEYGLLQVPIFGALIAGNLLLARLTSRRTVRSLIIMGGWPIMIGLL
VAAAATVISSHAYLWMTAGLSIYAFGIGLANAGLVRLTLFASDMSKGTVSAAMGMLQMLI
FTVGIEISKHAWLNGGNGLFNLFNLVNGILWLSLMVIFLKDKQMGNSHEG
NT seq 1233 nt   +upstreamnt  +downstreamnt
atgcaaaataaattagcttccggtgccaggcttggacgtcaggcgttacttttccctctc
tgtctggtgctttacgaattttcaacctatatcggcaacgatatgattcaacccggtatg
ttggccgtggtggaacaatatcaggcgggcattgattgggttcctacttcgatgaccgcg
tatctggcgggcgggatgtttttacaatggctgctggggccgctgtcggatcgtattggt
cgccgtccggtgatgctggcgggagtggtgtggtttatcgtcacctgtctggcaatattg
ctggcgcaaaacattgaacaattcaccctgttgcgcttcttgcagggcataagcctctgt
ttcattggcgctgtgggatacgccgcaattcaggaatccttcgaagaggcggtttgtatc
aagatcaccgcgctgatggcgaacgtggcgctgattgctccgctacttggtccgctggtg
ggcgcggcgtggatccatgtgctgccctgggaggggatgtttgttttgtttgccgcattg
gcagcgatctcctttttcggtctgcaacgagccatgcctgaaaccgccacgcgtataggc
gagaaactgtcactgaaagaactcggtcgtgactataagctggtgctgaagaacggccgc
tttgtggcgggggcgctggcgctgggattcgttagtctgccgttgctggcgtggatcgcc
cagtcgccgattatcatcattaccggcgagcagttgagcagctatgaatatggcttgctg
caagtgcctattttcggggcgttaattgcgggtaacttgctgttagcgcgtctgacctcg
cgccgcaccgtacgttcgctgattattatgggcggctggccgattatgattggtctattg
gtcgctgctgcggcaacggttatctcatcgcacgcgtatttatggatgactgccgggtta
agtatttatgctttcggtattggtctggcgaatgcgggactggtgcgattaaccctgttt
gccagcgatatgagtaaaggtacggtttctgccgcgatgggaatgctgcaaatgctgatc
tttaccgttggtattgaaatcagcaaacatgcctggctgaacgggggcaacggactgttt
aatctcttcaaccttgtcaacggaattttgtggctgtcgctgatggttatctttttaaaa
gataaacagatgggaaattctcacgaagggtaa

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Ontology (3)   
   KEGG BRITE (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   ASAP (1)   
   ECOCYC (1)   
   OC (1)   
   PASTEUR (1)   
   REGULONDB (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
3D Structure (12)   
   PDB (12)   
Protein domain (2)   
   Pfam (2)   
All databases (35)   

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