KEGG E.coli: b3774

Escherichia coli K-12 MG1655: b3774

Entry

b3774 CDS E.coli

Gene name ilvC, ECK3766, JW3747

Definition ketol-acid reductoisomerase, NAD(P)-binding (EC:1.1.1.86)

Orthology K00053 ketol-acid reductoisomerase [EC:1.1.1.86]

Pathway eco00290 Valine, leucine and isoleucine biosynthesis
eco00770 Pantothenate and CoA biosynthesis
eco01100 Metabolic pathways

Class Metabolism; Amino Acid Metabolism; Valine, leucine and isoleucine
biosynthesis [PATH:eco00290]
Metabolism; Metabolism of Cofactors and Vitamins; Pantothenate and
CoA biosynthesis [PATH:eco00770]

SSDB

Motif Pfam: IlvN IlvC 2-Hacid_dh_C ApbA AdoHcyase_NAD F420_oxidored
GFO_IDH_MocA

Other DBs NCBI-GI: 16131632
NCBI-GeneID: 948286
RegulonDB: B3774
EcoGene: EG10495
ECOCYC: EG10495
UniProt: P05793

Structure

PDB: 1YRL

Position 3955993..3957468

AA seq 491 aa
MANYFNTLNLRQQLAQLGKCRFMGRDEFADGASYLQGKKVVIVGCGAQGLNQGLNMRDSG
LDISYALRKEAIAEKRASWRKATENGFKVGTYEELIPQADLVINLTPDKQHSDVVRTVQP
LMKDGAALGYSHGFNIVEVGEQIRKDITVVMVAPKCPGTEVREEYKRGFGVPTLIAVHPE
NDPKGEGMAIAKAWAAATGGHRAGVLESSFVAEVKSDLMGEQTILCGMLQAGSLLCFDKL
VEEGTDPAYAEKLIQFGWETITEALKQGGITLMMDRLSNPAKLRAYALSEQLKEIMAPLF
QKHMDDIISGEFSSGMMADWANDDKKLLTWREETGKTAFETAPQYEGKIGEQEYFDKGVL
MIAMVKAGVELAFETMVDSGIIEESAYYESLHELPLIANTIARKRLYEMNVVISDTAEYG
NYLFSYACVPLLKPFMAELQPGDLGKAIPEGAVDNGQLRDVNEAIRSHAIEQVGKKLRGY
MTDMKRIAVAG

NT seq 1476 nt +upstreamnt +downstreamnt
atggctaactacttcaatacactgaatctgcgccagcagctggcacagctgggcaaatgt
cgctttatgggccgcgatgaattcgccgatggcgcgagctaccttcagggtaaaaaagta
gtcatcgtcggctgtggcgcacagggtctgaaccagggcctgaacatgcgtgattctggt
ctcgatatctcctacgctctgcgtaaagaagcgattgccgagaagcgcgcgtcctggcgt
aaagcgaccgaaaatggttttaaagtgggtacttacgaagaactgatcccacaggcggat
ctggtgattaacctgacgccggacaagcagcactctgatgtagtgcgcaccgtacagcca
ctgatgaaagacggcgcggcgctgggctactcgcacggtttcaacatcgtcgaagtgggc
gagcagatccgtaaagatatcaccgtagtgatggttgcgccgaaatgcccaggcaccgaa
gtgcgtgaagagtacaaacgtgggttcggcgtaccgacgctgattgccgttcacccggaa
aacgatccgaaaggcgaaggcatggcgattgccaaagcctgggcggctgcaaccggtggt
caccgtgcgggtgtgctggaatcgtccttcgttgcggaagtgaaatctgacctgatgggc
gagcaaaccatcctgtgcggtatgttgcaggctggctctctgctgtgcttcgacaagctg
gtggaagaaggtaccgatccagcatacgcagaaaaactgattcagttcggttgggaaacc
atcaccgaagcactgaaacagggcggcatcaccctgatgatggaccgtctctctaacccg
gcgaaactgcgtgcttatgcgctttctgaacagctgaaagagatcatggcacccctgttc
cagaaacatatggacgacatcatctccggcgaattctcttccggtatgatggcggactgg
gccaacgatgataagaaactgctgacctggcgtgaagagaccggcaaaaccgcgtttgaa
accgcgccgcagtatgaaggcaaaatcggcgagcaggagtacttcgataaaggcgtactg
atgattgcgatggtgaaagcgggcgttgaactggcgttcgaaaccatggtcgattccggc
atcattgaagagtctgcatattatgaatcactgcacgagctgccgctgattgccaacacc
atcgcccgtaagcgtctgtacgaaatgaacgtggttatctctgataccgctgagtacggt
aactatctgttctcttacgcttgtgtgccgttgctgaaaccgtttatggcagagctgcaa
ccgggcgacctgggtaaagctattccggaaggcgcggtagataacgggcaactgcgtgat
gtgaacgaagcgattcgcagccatgcgattgagcaggtaggtaagaaactgcgcggctat
atgacagatatgaaacgtattgctgttgcgggttaa

All links

Pathway (3)   
   KEGG PATHWAY (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (8)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (3)   
   ECOCYC (1)   
   ECOGENE (1)   
   REGULONDB-ECO (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (4)   
   GenBank (2)   
   EMBL (2)   
3D Structure (1)   
   PDB (1)   
Protein domain (7)   
   Pfam (7)   
All databases (27)

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