| Entry |
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| Gene name |
murE
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| Definition |
(RefSeq) UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase
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| KO |
| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC: 6.3.2.13] |
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| Organism |
ect Escherichia coli O7:K1 IAI39 (ExPEC)
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| Pathway |
| Lysine biosynthesis | | Peptidoglycan biosynthesis |
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| Brite |
KEGG Orthology (KO) [BR:ect00001]
Metabolism
Amino acid metabolism
00300 Lysine biosynthesis
ECIAI39_0088 (murE)
Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
ECIAI39_0088 (murE)
Enzymes [BR:ect01000]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.13 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate---2,6-diaminopimelate ligase
ECIAI39_0088 (murE)
Peptidoglycan biosynthesis and degradation proteins [BR:ect01011]
Precursor biosynthesis
Amino acid ligase
ECIAI39_0088 (murE)
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| SSDB |
    |
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| Motif |
 |
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| Other DBs |
NCBI-GeneID: NCBI-ProteinID: UniProt: |
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| Structure |
PDB: |
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| Position |
103388..104875
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| AA seq |
495 aa  
MADRNLRDLLAPWVPDAPSRALREMTLDSRVAAAGDLFVAVVGHQADGRRYIPQAIAQGV
AAIIAEAKDEATDGEIREMHGVPVIYLSQLNERLSALAGRFYHEPSDNLRLVGVTGTNGK
TTTTQLLAQWSQLLGETSAVMGTVGNGLLGKVIPTENTTGSAVDVQHELAGLVDQGATFC
AMEVSSHGLVQHRVAALKFAASVFTNLSRDHLDYHGDMEHYEAAKWLLYSEHHCGQAIIN
ADDEVGRRWLAKLPDAVAVSMEDHINPNCHGRWLKATEVNYHDSGATIRFSSSWGDGEIE
SHLMGAFNVSNLLLALATLLALGYPLAELLKTAARLQPVCGRMEVFTAPGKPTVVVDYAH
TPDALEKALQAARLHCAGKLWCVFGCGGDRDKGKRPLMGAIAEEFADVAVVTDDNPRTEE
PRAIINDILAGMLDAGHAKVMEGRAEAVTCAVMQAKENDVVLVAGKGHEDYQIVGNQRLD
YSDRVTVARLLGVIA |
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| NT seq |
1488 nt  +upstreamnt +downstreamnt
gtggcagatcgtaatttgcgcgaccttcttgctccgtgggtgccagacgcaccttcgcga
gcactgcgagagatgacactcgacagccgtgtggctgcggcgggcgatctctttgtagct
gtagtaggtcatcaggcggacgggcgtcgatatatcccgcaggcgatagcgcaaggtgtg
gctgccattattgcagaggcgaaagatgaggcgaccgacggtgaaatccgtgaaatgcac
ggcgtaccggtcatctatctcagccagctcaacgagcgtttatctgcactggcgggccgc
ttttaccatgaaccctctgacaatttacgtcttgtaggcgtaacgggcaccaacggcaaa
accacgacgacccagctgctggcacagtggagccaactgcttggcgaaaccagcgcggta
atgggcaccgttggtaacggcctgctggggaaagtgatcccgacagaaaataccaccggt
tcggcagtcgatgttcagcatgagctggcggggctggtggatcagggcgcgactttttgc
gcaatggaagtttcctcccacggactggtacagcaccgtgtggcggcattgaaatttgcg
gcatcggtctttaccaacttaagccgcgatcaccttgattatcatggtgatatggaacac
tacgaagccgcgaaatggctgctttattctgagcatcattgcggtcaggcgattattaac
gccgacgatgaagtgggccgccgctggctggcaaaactgccggacgcggttgcggtatca
atggaagatcatatcaatccgaactgtcacggacgctggttgaaagcgactgaagtgaac
tatcacgacagcggtgcgactattcgctttagctcaagctggggcgatggggaaattgaa
agccatctgatgggcgcttttaacgtcagcaacctgctgctggcgctggcgacgctgctg
gcgctgggctatccactggctgagctgctgaaaaccgccgcgcgtctgcaaccggtttgc
ggacgtatggaagtgttcactgcaccaggcaaaccgacggtggtggtggattacgcgcat
acgccagatgcactggaaaaagccttacaggcggcgcgcctgcactgtgcgggcaagctg
tggtgcgtctttggctgtggtggcgatcgtgataaaggcaaacgtccactgatgggcgca
attgctgaagagtttgctgacgtggcggtggtaacggacgataacccgcgtaccgaagaa
ccgcgtgccatcatcaacgatattctggcgggaatgttagatgccggacatgccaaagtg
atggaaggccgtgctgaagcggtgacttgcgccgttatgcaggctaaagagaatgatgtg
gtactggtcgcgggcaaaggtcatgaggattaccagattgttggcaatcagcgtctggac
tactccgatcgcgtcacggtggcgcgtctgctgggggtgattgcatga |
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