KEGG   Escherichia coli APEC O1 (APEC): APECO1_2469
Entry
APECO1_2469       CDS       T00425                                 
Symbol
purH
Name
(GenBank) bifunctional AICAR formyltransferase/IMP cyclohydrolase PurH
  KO
K00602  phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
Organism
ecv  Escherichia coli APEC O1 (APEC)
Pathway
ecv00230  Purine metabolism
ecv00670  One carbon pool by folate
ecv01100  Metabolic pathways
ecv01110  Biosynthesis of secondary metabolites
Module
ecv_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:ecv00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    APECO1_2469 (purH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    APECO1_2469 (purH)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:ecv04147]
    APECO1_2469 (purH)
Enzymes [BR:ecv01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.3  phosphoribosylaminoimidazolecarboxamide formyltransferase
     APECO1_2469 (purH)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.10  IMP cyclohydrolase
     APECO1_2469 (purH)
Exosome [BR:ecv04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   APECO1_2469 (purH)
SSDB
Motif
Pfam: AICARFT_IMPCHas MGS NSP2_assoc
Other DBs
NCBI-ProteinID: ABJ03467
UniProt: A1AIH7
Position
complement(4526454..4528043)
AA seq 529 aa
MQQRRPVRRALLSVSDKAGIVEFAQALSARGVELLSTGGTARLLAEKGLPVTEVSDYTGF
PEMMDGRVKTLHPKVHGGILGRRGQDDTIMEEHQIQPIDMVVVNLYPFAQTVAREGCSLE
DAVENIDIGGPTMVRSAAKNHKDVAIVVKSSDYDAIIKEIDANEGSLTLETRFDLAIKAF
EHTAAYDSMIANYFGSMVPAYHGESKEAAGRFPRTLNLNFIKKQDMRYGENSHQQAAFYI
EENVKEASVATATQVQGKALSYNNIADTDAALECVKEFAEPACVIVKHANPCGVAIGNSI
LDAYDRAYKTDPTSAFGGIIAFNRELDAETAQAIISRQFVEVIIAPSASEEALKITAAKQ
NVRVLTCGQWGERVPGLDFKRVNGGLLVQDRDLGMVGAEELRVVTKRQPTEQELRDALFC
WKVAKFVKSNAIVYAKNNMTIGIGAGQMSRVYSAKIAGIKAADEGLEVKGSSMASDAFFP
FRDGIDAAAAAGVTCVIQPGGSIRDDEVIAAADEHGIAMLFTDMRHFRH
NT seq 1590 nt   +upstreamnt  +downstreamnt
atgcaacaacgtcgtccagtccgccgcgctctgctcagtgtttctgacaaagccggtatc
gtcgaattcgcccaggcactttccgcacgcggtgtggagctgctgtctacagggggcaca
gcccgtctgttagcagaaaaaggtctgccggtaaccgaagtttccgattacaccggtttc
ccggagatgatggatggacgcgtgaagaccctgcatccgaaagtacatggtggaattctg
ggccgtcgcggccaggacgataccattatggaagaacatcagatccagcctatcgatatg
gtggttgttaacctgtatccgttcgcccagaccgttgctcgtgaaggctgctcgctggaa
gatgcggttgagaacatcgatatcggcggcccgacgatggtgcgctctgccgccaagaac
cataaagatgtcgcaatcgtggtgaagagcagcgactacgacgccattattaaagagata
gatgccaatgaaggctccctgactctggaaactcgctttgaccttgccatcaaagccttc
gaacacaccgccgcctacgacagcatgattgccaactacttcggcagcatggttccggct
taccacggtgaaagcaaagaagccgccggtcgcttcccacgcacgctgaacctgaacttc
attaagaagcaggatatgcgttacggcgagaacagccaccagcaggctgccttctatata
gaagagaatgtgaaagaagcctccgttgctactgcaacccaggttcaaggtaaagccctc
tcttataacaacatcgccgacaccgatgcggcgctggagtgcgtgaaagagttcgccgag
ccggcatgtgtgattgtgaaacacgccaacccttgcggcgtggctatcggcaattccatt
cttgatgcttacgatcgcgcgtacaaaaccgacccaacctccgcattcggcggcatcatt
gcctttaaccgcgaactggatgctgaaaccgcgcaggccatcatttctcgtcagttcgtc
gaagtgattattgcgccgtccgccagcgaagaagccctgaaaatcaccgccgccaagcaa
aacgtacgcgttctgacctgcggtcagtggggcgagcgtgttccgggtcttgatttcaaa
cgcgtgaacggcggtctgctggttcaggatcgcgatctggggatggtcggtgcagaagaa
ctgcgcgtcgtcaccaaacgccagccgaccgaacaggaattgcgtgatgcgctgttctgc
tggaaagtggcgaagttcgtgaaatccaacgctatcgtctatgccaaaaacaatatgacc
atcggtattggcgcgggccagatgagccgcgtgtactccgcgaaaatcgccggtattaaa
gccgccgatgaaggtctggaagtgaaaggttcctcgatggcttctgacgcgttcttcccg
ttccgcgacggtattgatgccgccgccgctgcgggcgtgacctgtgtaatccagcctggc
ggttccatccgtgatgacgaagtgattgccgccgccgacgagcacggtattgcgatgctc
ttcaccgacatgcgccacttccgccattaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (4)   
   KEGG ENZYME (2)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   SWISS-PROT (1)   
Protein domain (3)   
   Pfam (3)   
All databases (27)   

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