KEGG   Escherichia coli O45 K1 H7 S88 (ExPEC): ECS88_2925
Entry
ECS88_2925        CDS       T00830                                 
Symbol
gabD
Name
(GenBank) succinate-semialdehyde dehydrogenase I, NADP-dependent
  KO
K00135  succinate-semialdehyde dehydrogenase / glutarate-semialdehyde dehydrogenase [EC:1.2.1.16 1.2.1.79 1.2.1.20]
Organism
ecz  Escherichia coli O45:K1:H7 S88 (ExPEC)
Pathway
ecz00250  Alanine, aspartate and glutamate metabolism
ecz00310  Lysine degradation
ecz00350  Tyrosine metabolism
ecz00650  Butanoate metabolism
ecz00760  Nicotinate and nicotinamide metabolism
ecz01100  Metabolic pathways
ecz01120  Microbial metabolism in diverse environments
Module
ecz_M00027  GABA (gamma-Aminobutyrate) shunt
ecz_M00956  Lysine degradation, bacteria, L-lysine => succinate
Brite
KEGG Orthology (KO) [BR:ecz00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00650 Butanoate metabolism
    ECS88_2925 (gabD)
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    ECS88_2925 (gabD)
   00310 Lysine degradation
    ECS88_2925 (gabD)
   00350 Tyrosine metabolism
    ECS88_2925 (gabD)
  09108 Metabolism of cofactors and vitamins
   00760 Nicotinate and nicotinamide metabolism
    ECS88_2925 (gabD)
Enzymes [BR:ecz01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.16  succinate-semialdehyde dehydrogenase [NAD(P)+]
     ECS88_2925 (gabD)
    1.2.1.20  glutarate-semialdehyde dehydrogenase
     ECS88_2925 (gabD)
    1.2.1.79  succinate-semialdehyde dehydrogenase (NADP+)
     ECS88_2925 (gabD)
SSDB
Motif
Pfam: Aldedh
Other DBs
NCBI-ProteinID: CAR04172
UniProt: B7MKD2
Position
2878470..2879918
AA seq 482 aa
MKLNDSNLFRQQALINGEWLDANNGEVIDVTNPANGDKLGSVPKMGADETRAAIDAANRA
LPVWRALTAKERANILRNWFNLMMEHQDDLARLMTLEQGKPLAEAKGEISYAASFIEWFA
EEGKRIYGDTIPGHQADKRLIVIKQPIGVTAAITPWNFPAAMITRKAGPALAAGCTMVLK
PASQTPFSALALAELAIRAGVPAGVFNVVTGSAGAVGNELTSNPLVRKLSFTGSTEIGRQ
LMEQCAKDIKKVSLELGGNAPFIVFDDADLDKAVEGALASKFRNAGQTCVCANRLYVQNG
VYDRFAEKLQQAVSKLHIGNGLEKGVTIGPLIDEKAVAKVEEHIADALEKGARVVCGGKA
HERGGNFFQPTILVDVPANAKVSKEETFGPLAPLFRFKDEADVIAQANDTEFGLAAYFYA
RDLSRVFRVGEALEYGIIGINTGIISNEVAPFGGIKASGLGREGSKYGIEDYLEIKYMCI
GL
NT seq 1449 nt   +upstreamnt  +downstreamnt
atgaaacttaacgacagtaacttattccgccagcaggcgttgattaacggggaatggctg
gacgccaacaatggcgaggtcatcgacgtcaccaatccggcgaacggcgacaagctgggt
agcgtgccgaaaatgggcgctgatgaaacccgcgccgctatcgacgccgccaaccgcgcc
ctgcccgtctggcgtgcgctcactgccaaagaacgcgccaacattctgcgcaactggttc
aatttaatgatggagcatcaggacgatttagcgcgcctgatgaccctcgaacagggcaaa
ccactggctgaagcgaaaggcgaaatcagctacgccgcctcatttattgagtggtttgca
gaagaaggcaaacgtatttatggcgacaccattcccggtcatcaggccgataaacgcctg
attgttatcaagcagccgattggcgtcaccgcggctatcacgccgtggaacttcccggcg
gcgatgattacccgtaaagccggtccggcgctggcggcaggctgcacgatggtgctgaag
cccgccagtcagacgccgttctctgcgctggcgctggcagaactggcgattcgcgcgggc
gttccggctggcgtgtttaacgtagtcaccggttcggcgggcgcggtcggtaacgaactg
accagcaacccgctggtgcgcaagctgtcgtttaccggctcgaccgaaattggccgtcag
ttaatggaacagtgcgcgaaagacatcaaaaaagtgtcgctggagctgggcggcaacgca
ccgtttattgtctttgacgatgccgatctcgataaagccgtggaaggcgcgctggcctcg
aaattccgtaacgccgggcaaacctgcgtctgcgccaaccgcctgtatgtgcagaacggc
gtgtatgaccgctttgccgaaaaattgcagcaggcggtgagcaaactgcacatcggcaac
gggctggagaaaggcgtcaccatcgggccgctgatcgatgaaaaagcggtagcaaaagtg
gaagagcatattgccgatgcgctggagaaaggcgcgcgcgtggtttgcggcggtaaagca
catgaacgcggcggtaacttcttccagccgaccattctggtggacgttccggctaacgcc
aaagtgtcgaaagaagagacgtttggccccctcgccccgctgttccgttttaaagatgaa
gccgatgtgattgcgcaagccaatgacaccgaatttggccttgcagcctatttctacgcc
cgtgatttaagccgcgtcttccgcgtgggcgaagcactggagtacggcatcatcggcatc
aacaccggcattatttccaatgaagtggccccgtttggcggcattaaagcctcgggtctg
ggtcgtgaaggttcgaagtatggcatcgaagattacttagaaatcaaatatatgtgcatc
ggtctttaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (10)   
   KEGG PATHWAY (7)   
   KEGG MODULE (3)   
Chemical substance (10)   
   KEGG COMPOUND (10)   
Chemical reaction (6)   
   KEGG ENZYME (3)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (1)   
   Pfam (1)   
All databases (34)   

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