KEGG T01718: EKO11

Escherichia coli KO11FL: EKO11_2816

Entry

EKO11_2816 CDS T01718

Definition

delta-1-pyrroline-5-carboxylate dehydrogenase

Orthology

K13821

proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.99.8 1.5.1.12]

Organism

eko Escherichia coli KO11FL

Pathway

eko00250	Alanine, aspartate and glutamate metabolism
eko00330	Arginine and proline metabolism
eko01100	Metabolic pathways
eko01110	Biosynthesis of secondary metabolites

Class

Metabolism; Amino acid metabolism; Alanine, aspartate and glutamate metabolism [PATH:eko00250]
Metabolism; Amino acid metabolism; Arginine and proline metabolism [PATH:eko00330]

SSDB

Motif

Pfam:

Pro_dh Aldedh Pro_dh-DNA_bdg

Other DBs

NCBI-GI:

378713581

NCBI-GeneID:

11777575

UniProt:

E8Y215

Structure

PDB:

2GPE 2AY0 2RBF

Position

2919428..2923390

AA seq 1320 aa
MGTTTMGVKLDDATRERIKSAATRIDRTPHWLIKQAIFSYLEQLENSDTLPELPALLSGA
ANESDEAPTPAEEPHQPFLDFAEQILPQSVSRAAITAAYRRPETEAVSMLLEQARLPQPV
AEQAHKLAYQLADKLRNQKNASGRAGMVQGLLQEFSLSSQEGVALMCLAEALLRIPDKAT
RDALIRDKISNGNWQSHIGRSPSLFVNAATWGLLFTGKLVSTHNEAILSRSLNRIIGKSG
EPLIRKGVDMAMRLMGEQFVTGETIAEALANARKLEEKGFRYSYDMLGEAALTAADAQAY
MVSYQQAIHAIGKASNGRGIYEGPGISIKLSALHPRYSRAQYDRVMEELYPRLKSLTLLA
RQYDIGINIDAEEADRLEISLDLLEKLCFEPELAGWNGIGFVIQAYQKRCPLVIDYLIDL
ATRSRRRLMIRLVKGAYWDSEIKRAQMDGLEGYPVYTRKVYTDVSYLACAKKLLAVPNLI
YPQFATHNAHTLAAIYQLAGQNYYPGQYEFQCLHGMGEPLYEQVTGKVADGKLNRPCRIY
APVGTHETLLAYLVRRLLENGANTSFVNRIADTSLPLDELVADPVTAVEKLAQQEGQTGL
PHPKIPLPRDLYGHGRDNSAGLDLANEHRLASLSSALLNSALQKWQALPMLEQPVAAGEM
SPVINPAEPKDIVGYVREATPREVEQALESAVNNAPIWFATPPVERAAILHRAAVLMESQ
MQQLIGILVREAGKTFSNAIAEVREAVDFLHYYAGQVRDDFANETHRPLGPVVCISPWNF
PLAIFTGQIAAALAAGNSVLAKPAEQTPLIAAQGIAILLEAGVPPGVVQLLPGQGETVGA
QLTGDDRVRGVMFTGSTEVATLLQRNIASRLDAQGRPIPLIAETGGMNAMIVDSSALTEQ
VVVDVLASAFDSAGQRCSALRVLCLQDEIADHTLKMLRGAMAECRMGNPGRLTTDIGPVI
DSEAKANIERHIQTMRSKGRPVFQAVRENSEDAREWQSGTFVAPTLIELDDFAELQKEVF
GPVLHVVRYNRNQLPELIEQINASGYGLTLGVHTRIDETIAQVTGSAHVGNLYVNRNMVG
AVVGVQPFGGEGLSGTGPKAGGPLYLYRLLANRPESALAVTLARQDAEYPVDAQLKAALT
QPLNALREWAANRPELQALCTQYGELAQAGTQRLLPGPTGERNTWTLLPRERVLCIADDE
QDALTQLAAVLAVGSQVLWPDDALHRQLVKALPSAVSERIQLAKAENITAQPFDAVIFHG
DSDQLRALCEAVAARDGAIVSVQGFARGESNILLERLYIERSLSVNTAAAGGNASLMTIG

NT seq 3963 nt +upstreamnt +downstreamnt
atgggaaccaccaccatgggggttaagctggacgacgcgacgcgtgagcgtattaagtct
gccgcgacacgtatcgatcgcacaccacactggttaattaagcaggcgattttttcttat
ctcgaacaactggaaaacagcgatactctgccagagctacctgcgctgctttctggcgct
gccaatgagagcgatgaagcaccgactccggcagaggaaccacaccagccattcctcgac
tttgccgagcaaattttgccccagtcggtttcccgcgccgcgatcaccgcggcctatcgt
cgcccggaaaccgaagcggtttctatgctgctggaacaagcccgcctgccgcagccagtt
gctgaacaggcgcacaaactggcgtatcaactggccgataaactgcgtaatcaaaaaaat
gccagtggtcgcgcaggtatggtccaggggttattgcaggagttttcgctgtcatcgcag
gaaggcgtggcgctgatgtgtctggcagaagcgttgttgcgtattcccgacaaagccacc
cgcgacgcgttaattcgcgacaaaatcagcaacggtaactggcagtcacacattggtcgt
agcccgtcactgtttgttaatgccgccacctgggggctgctgtttactggcaaactggtt
tccacccataacgaagccatcctctcccgctcgctgaaccgcattatcggtaaaagcggt
gaaccgctgatccgcaaaggtgtggatatggcgatgcgcctgatgggcgagcagttcgtc
acgggtgaaaccatcgcggaagcgttagccaatgcccgcaagctggaagagaaaggtttc
cgttactcttacgatatgctgggcgaagctgcactgactgccgcagacgcacaggcgtat
atggtttcctatcagcaggcgattcacgccatcggtaaagcgtctaacggtcgtggcatc
tatgaagggccgggcatttcaatcaaactgtcggcgctgcatccgcgttatagccgcgcc
cagtatgaccgggtaatggaagaactttacccgcgtctgaaatcactcaccctgctggcg
cgtcagtatgatattggtattaacatcgatgccgaagaggccgatcgtctggagatctcc
ctcgatctgctggaaaaactctgtttcgagccggaactggcaggctggaacggcatcggt
tttgttattcaggcttatcaaaaacgctgcccgttggtgattgattacctgattgatctc
gccacccgtagccgtcgccgtctgatgattcgtctggtgaaaggcgcgtactgggatagt
gaaattaagcgtgcgcagatggacggccttgaaggttatccggtttatacccgcaaggtg
tataccgacgtttcttatctcgcctgtgcgaaaaaactgctggcggtgccgaatctaatc
tacccgcagttcgcgacgcacaacgcccatacgctggcagcgatttatcaactggcaggt
cagaactactatccgggtcagtacgagttccagtgcctgcatggtatgggcgagccactg
tacgagcaggtcaccgggaaagttgccgacggtaaacttaaccgaccgtgtcgtatttat
gccccggttggcacacatgaaacgctgctggcgtatctggtgcgtcgcctgctggaaaac
ggtgctaacacctcgtttgttaaccgtattgccgacacctctttgccactggatgaactg
gtcgccgatccggtcactgctgtagaaaaactggcgcaacaggaagggcaaactggatta
ccgcatccgaaaattcccctgccgcgcgatctttacggtcacgggcgcgacaactcggca
gggctggatctcgctaacgaacaccgtctggcctcgctctcctctgccctgctcaatagt
gcactgcaaaaatggcaggccttgccaatgctggaacaaccggtagcggcaggtgagatg
tcgcccgttattaaccctgcggaaccgaaagatattgtgggctatgtgcgtgaagccacg
ccgcgtgaggtagaacaggcgctggaaagtgcggttaataacgcgccaatctggtttgcc
actcctccggttgaacgcgcggcgattttgcatcgcgctgccgtgctaatggaaagccag
atgcagcaactgattggtattctggtgcgtgaagccggaaaaaccttcagtaacgccatt
gccgaagtgcgcgaagcggtcgattttctccactactatgccggacaggtgcgggatgat
ttcgctaacgaaacccaccgtccattagggcctgtggtgtgtatcagtccgtggaacttc
ccgctggctattttcaccgggcagattgctgccgcactggcggcaggtaacagcgtgctg
gcaaaaccggcagaacaaacgccgctgattgccgcgcaagggatcgccattttgctggaa
gcgggtgtaccgccaggcgtggtgcagttgctgccaggtcagggggaaaccgtgggcgcg
caactgacgggtgatgatcgcgtacgcggggtgatgtttaccggttcaaccgaagtcgct
acgttactgcagcgcaatatcgccagccgcctggacgctcagggtcgccctattccgctc
atcgctgaaaccggcggcatgaacgcgatgattgtcgattcttcagcactgaccgaacag
gtcgtcgtggatgtactggcctcggcgttcgacagtgcgggtcagcgttgttcggcgctg
cgcgtgctgtgcctgcaagatgagattgccgaccacacgttgaaaatgctgcgcggcgca
atggccgaatgccggatgggtaatccgggtcgcctgaccaccgatatcggtccggtgatt
gatagcgaagcgaaagccaatattgagcgccatattcagaccatgcgtagcaaaggccgt
ccggtgttccaggcggtgcgggaaaacagcgaagatgcccgtgaatggcaaagcggcacc
tttgtcgccccgacgctgatcgaactggatgactttgccgaattgcaaaaagaggtcttt
ggtccggtgctgcatgtggtgcgttacaaccgtaaccagctaccagagctgatcgagcag
attaacgcttccggctatggtctgacgcttggtgtccatacgcgtattgatgaaaccatc
gcccaggtcactggctcggcccatgttggtaacctgtatgttaaccgtaatatggtgggc
gcagtggtgggtgtgcagccattcggcggcgaagggttgtccggtaccgggccgaaagca
ggcggtccgctctatctctaccgtctgctggcgaatcgcccggaaagtgcgctggcagtg
acgctcgcgcgtcaggatgcagagtatccggtcgatgcacagttgaaagccgcattgact
cagccgctaaatgcactgcgggaatgggcagcaaatcgtccagaattgcaggcgttatgt
acgcaatatggcgagctggcgcaggcaggaacacaacgattgctgccggggccgacgggt
gaacgcaacacctggacgctgctgccgcgtgagcgcgtgttgtgtattgccgatgatgag
caggatgcgctgactcagctcgccgccgtgctggcggtgggcagccaggtactgtggccg
gatgacgcgctgcatcgtcagctagtaaaggcattgccatcggcagtcagcgaacgtatt
caactggcgaaagcggaaaatataaccgctcaaccctttgatgcggtgatcttccacggt
gattcggatcagcttcgcgcattgtgtgaagccgttgctgcgcgggatggcgcaattgtt
tcggtgcagggttttgcccgtggcgaaagcaatatccttctggaacggctgtatatcgaa
cgttcgctgagtgtgaataccgctgccgctggcggtaacgccagtttaatgacgatcggt
taa

All links

Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (15)   
   KEGG COMPOUND (15)   
Chemical reaction (9)   
   KEGG ENZYME (2)   
   KEGG REACTION (7)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
3D Structure (3)   
   PDB (3)   
Protein domain (3)   
   Pfam (3)   
All databases (41)   

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