KEGG   Eggerthella lenta: Elen_0380
Entry
Elen_0380         CDS       T00984                                 
Name
(GenBank) 2-isopropylmalate synthase/homocitrate synthase family protein
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
ele  Eggerthella lenta
Pathway
ele00290  Valine, leucine and isoleucine biosynthesis
ele00620  Pyruvate metabolism
ele01100  Metabolic pathways
ele01110  Biosynthesis of secondary metabolites
ele01210  2-Oxocarboxylic acid metabolism
ele01230  Biosynthesis of amino acids
Module
ele_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:ele00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    Elen_0380
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    Elen_0380
Enzymes [BR:ele01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     Elen_0380
SSDB
Motif
Pfam: HMGL-like LeuA_dimer
Other DBs
NCBI-ProteinID: ACV54370
UniProt: C8WKR4
Position
489797..491380
AA seq 527 aa
MNRILTYDSTLRDGEQCEGITLSLEDKLRIVERLDAFGVDFIEGGFPASNPKDIAFFQRV
QEMPLKHARIVAFGSTCKKDVAAEDDRGLADLVASGAPVVTIVGKTWDEQVTRALLTTLD
ENLRMIRDSVAYLKAQGLTVVFDAEHFFDGYKANADYAMACVRAASEAGADSIDLCETNG
GALPHEVDAVVAAVARELPGQQLGIHCHNDSGCAVANSLAAVRAGVTQVQGTVNGFGERV
GNTDLLTVIADLELKMGCTCVGEERLRDLTSVAQFVAETCNLSVPNHHPYTGASAFAHKG
GLHASAIARFPEAYEHTRPEAVGNTQRMLVSELAGKASLIAKAKNLGIDLAQHPDKTQEI
LDDIKRREAVGYSYEVADGSLALLLQWHLGAYRPHFTLESFRVIVDDHEDTGALAKDAMS
EATIKIHVGDQRFVATGEGAGPVGALDNALRMAIVAFYPEVADIELVDYKVRILDENVGT
DAITRVVITTRDKRGSWGTVGVSENIIEASWNALVDSIEYGLMRIGE
NT seq 1584 nt   +upstreamnt  +downstreamnt
gtgaatcgaatcctcacgtatgacagcacgctgcgagacggagagcagtgcgagggcatc
acgttgtcgcttgaggacaagctgcgcattgtcgagcgcttggacgcgttcggcgtcgat
ttcatcgagggcgggtttccggcatcgaacccgaaagacatcgcgttcttccagcgcgtg
caggagatgccgcttaagcatgcgcgcatcgtggcgttcggctcaacgtgcaagaaggac
gtcgccgccgaggacgaccgcgggctggccgacctcgtggccagcggcgccccggtggtc
accatcgtgggcaaaacgtgggacgagcaggtcacgcgcgcgctgctgaccacgctcgac
gagaacctgcgcatgatccgcgattccgtggcctacctcaaggcgcagggtctcacggtg
gtgttcgacgccgaacacttcttcgacggctacaaggcgaacgccgactacgcgatggcc
tgcgtgcgcgcggcaagcgaggcgggcgccgactccatcgacctatgcgagacgaacggc
ggcgcgctgcctcacgaggtggatgccgtcgtggccgcggtcgcgcgcgagctgcccggc
cagcagctgggcatccattgccacaacgattcgggctgcgctgtggcgaactcgcttgcc
gctgtgcgcgccggcgtaacccaggtgcagggcacggtgaacgggttcggcgaacgcgtg
ggcaataccgacctgctcaccgtcatcgccgacctcgagctgaagatgggctgcacgtgc
gtgggcgaggagcggctgcgcgacctgaccagcgtggcgcagttcgtggccgaaacgtgc
aacctgtcggtgccgaaccatcatccctacacgggcgcgtcggcgttcgcgcacaagggc
ggcctgcacgccagcgccatcgcgcgcttccccgaggcctacgagcacacgcgtcccgag
gcggtgggcaacacgcagcgcatgctggtcagcgagctggccggcaaggcatcgctcatc
gcgaaggcgaagaacttgggcatcgatctggcccagcaccccgacaagacgcaggagatc
ctggacgacatcaagcgccgcgaagcggtgggctactcctacgaggtggccgacgggtcg
cttgcgctgctgctgcaatggcatctcggcgcgtaccggccgcacttcacgctggagagc
ttccgcgtcatcgtggacgaccacgaggacaccggcgcgctggcgaaggacgccatgtcg
gaagccaccatcaagatccacgtgggcgaccagcgcttcgtggccacgggcgagggcgcg
ggtcctgtcggcgcgctggacaacgcgctgcgcatggccatcgtggcgttctatcctgag
gtggccgacatcgaactggtggactacaaggtgcgcatcctcgacgagaacgtgggcacc
gacgccatcacgcgagtcgtcatcaccacgcgtgacaagcgcggcagctggggcacggtg
ggcgtgtcggagaacatcatcgaagcatcatggaatgcgctggtcgactccatcgagtac
ggcctgatgcggattggggagtag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (2)   
   Pfam (2)   
All databases (33)   

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