KEGG   Escherichia coli O44 H18 042 (EAEC): EC042_0149
Entry
EC042_0149        CDS       T02067                                 
Symbol
mrcB
Name
(GenBank) penicillin-binding protein 1B [includes: penicillin-insensitive transglycosylase; penicillin sensitive transpeptidase]
  KO
K05365  penicillin-binding protein 1B [EC:2.4.99.28 3.4.16.4]
Organism
elo  Escherichia coli O44:H18 042 (EAEC)
Pathway
elo00550  Peptidoglycan biosynthesis
elo01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:elo00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    EC042_0149 (mrcB)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases [BR:elo01003]
    EC042_0149 (mrcB)
   01011 Peptidoglycan biosynthesis and degradation proteins [BR:elo01011]
    EC042_0149 (mrcB)
Enzymes [BR:elo01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.99  Transferring other glycosyl groups
    2.4.99.28  peptidoglycan glycosyltransferase
     EC042_0149 (mrcB)
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.16  Serine-type carboxypeptidases
    3.4.16.4  serine-type D-Ala-D-Ala carboxypeptidase
     EC042_0149 (mrcB)
Glycosyltransferases [BR:elo01003]
 Polysaccharide
  Bacterial polysaccharide (excluding LPS)
   EC042_0149 (mrcB)
Peptidoglycan biosynthesis and degradation proteins [BR:elo01011]
 Peptidoglycan biosynthesis and degradation
  Glycosyltransferase/DD-Transpeptidase (Class A PBP)
   EC042_0149 (mrcB)
SSDB
Motif
Pfam: Transgly UB2H PBP1_TM Transpeptidase UvrB_inter FtsA_C
Other DBs
NCBI-ProteinID: CBG32981
UniProt: D3GR96
Position
170620..173154
AA seq 844 aa
MAGNDREPIGRKEKPTRPVKQKVSRRRYEDDDDYDDYDDYEDEEPMPRKGKGKGKGRKPR
GKRGWLWLLLKLAIVFAVLIAIYGVYLDQKIRSRIDGKVWQLPAAVYGRMVNLEPDMTIS
KNEMVKLLEATQYRQVSKMTRPGEFTVQANSIEMIRRPFDFPDSKEGQVRARLTFDGDHL
ATIVNMENNRQFGFFRLDPRLITMISSPNGEQRLFVPRSGFPDLLVDTLLATEDRHFYEH
DGISLYSIGRAVLANLTAGRTVQGASTLTQQLVKNLFLSSERSYWRKANEAYMALIMDAR
YSKDRILELYMNEVYLGQSGDNEIRGFPLASLYYFGRPVEELSLDQQALLVGMVKGASIY
NPWRNPKLALERRNLVLRLLQQQQIIDQELYDMLSARPLGVQPRGGVISPQPAFMQLVRQ
ELQAKLGDKVKDLSGVKIFTTFDSVAQDAAEKAAVEGIPALKKQRKLSDLETAIVVVDRF
SGEVRAMVGGSEPQFAGYNRAMQARRSIGSLAKPATYLTALSQPKIYRLNTWIADAPIAL
RQPNGQVWSPQNDDRRYSESGRVMLVDALTRSMNVPTVNLGMALGLPAVTETWIKLGVPK
DQLHPVPAMLLGALNLTPIEVAQAFQTIASGGNRAPLSALRSVIAEDGKVLYQSFPQAER
AVPAQAAYLTLWTMQQVVQRGTGRQLGAKYPNLHLAGKTGTTNNNVDTWFAGIDGSTVTI
TWVGRDNNQPTKLYGASGAMSIYQRYLANQTPTPLNLVPPEDIADMGVDYDGNFVCSGGM
RVLPVWTSDPQSLCQQSEMQQQPSGNPFDQSSQPQQQPQQQPAQQEQKDSDGVAGWIKDM
FGSN
NT seq 2535 nt   +upstreamnt  +downstreamnt
atggccgggaatgaccgcgagccaattggacgcaaagagaaaccgacgcgtccggtcaaa
caaaaggtaagccgtcgtcgttacgaagatgacgatgattacgacgattatgatgactat
gaggatgaagaaccgatgccgcgcaaaggtaagggcaaaggcaaagggcgtaagcctcgt
ggcaaacgcggctggctatggctgctgctaaaactggctatcgtttttgccgtgctgatc
gccatttacggcgtttatctcgatcaaaaaattcgcagccgtattgatggcaaggtctgg
caattgcccgcggcagtttatggccggatggtcaaccttgagccagacatgaccatcagc
aagaacgagatggtgaagctgctggaggcgacccagtatcgtcaggtgtcgaaaatgacc
cgtcctggcgaatttaccgtgcaggccaacagcattgagatgatccgccgtccgtttgat
ttcccggacagcaaagaagggcaggtgcgcgcgcgtctgacctttgatggcgatcatctg
gcaacgatcgtcaatatggagaacaaccgtcagttcggtttcttccgtcttgatccgcgt
ctgatcaccatgatctcttcgccaaacggtgagcagcgtctgtttgtgccgcgcagtggt
ttccctgatttgctggtggatactttgctggcgacagaagaccgtcatttctacgagcat
gatgggatcagtctctactccatcggacgtgcggtgctggcaaacctgacagccggacgc
acggtgcagggtgcgagtacgctgacgcaacagctggtgaaaaacctgttcctctccagc
gagcgctcttactggcgtaaagcgaacgaagcttacatggcgctgatcatggacgcgcgt
tacagcaaagaccgtattcttgagctgtatatgaacgaggtgtatctcggtcagagcggc
gacaacgaaatccgcggcttcccgctggcaagcttgtattactttggtcgcccggtagaa
gagctaagcctcgaccagcaggcgctgttagtcggtatggtgaaaggggcgtccatctac
aacccgtggcgtaacccgaaactggcgctggagcgacgtaatctggtgctgcgtctgctg
caacagcaacagattattgatcaagaactctatgacatgttgagtgcacgtccgctgggt
gttcagccgcgcggtggggtgatctctcctcagccagcctttatgcagctggtgcgtcag
gagttgcaggcaaaactgggcgataaggtaaaagatctctccggcgtgaagatcttcact
acctttgactcggtggcccaggacgcggcagaaaaagccgccgtggaaggcattccggca
ctgaagaaacagcgtaagttgagcgatcttgaaactgcgattgtggtcgtcgaccgcttt
agtggtgaagttcgtgcgatggtcggtggttctgagccgcagtttgcgggctacaaccgt
gcgatgcaggcgcgtcgttcgattggttcccttgcaaaaccagcgacttatctgacggct
ttaagccagccgaaaatctatcgcctgaacacgtggattgccgatgcgccaatcgcgctg
cgtcagccgaatggccaggtctggtcaccgcagaatgatgaccgtcgttatagcgaaagt
ggcagagtgatgctggtggatgcgttgacccgttcgatgaacgtgccgacggtgaatctg
gggatggcgctggggctgcctgcggttacggagacctggatcaaactgggcgtaccgaaa
gatcagctgcatccggttccggcaatgctgctgggggcgttgaacttaacgccaatcgaa
gtggcgcaggcattccagaccatcgccagcggtggtaaccgtgcaccgctttctgcgctg
cgttcggtaatcgcggaagatggcaaagtgctgtatcagagcttcccgcaggcggaacgc
gctgttccggcgcaggcggcgtatctgacactatggaccatgcagcaggttgtacaacgc
ggtacgggtcgtcagcttggggcgaaatacccgaacctgcatctggcagggaaaacaggg
actaccaacaataacgtagatacctggtttgcgggcattgacggcagcacggtgaccatc
acctgggtaggccgtgataacaaccagccgaccaaactgtatggagccagcggggcaatg
tcgatttatcagcgttatctggctaaccagacgccaacaccgctgaatcttgttccgcca
gaagatattgcagatatgggcgtggactacgacggcaactttgtttgcagcggtggcatg
cgtgtcttgccggtctggaccagcgatccgcaatcgctgtgccagcagagtgagatgcag
cagcagccgtcaggcaatccgtttgatcagtcttcacagccgcagcaacagccgcaacag
caacctgctcagcaagagcagaaagacagcgacggtgtagccggttggattaaagatatg
tttggtagtaattaa

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical substance (3)   
   KEGG COMPOUND (3)   
Chemical reaction (4)   
   KEGG ENZYME (2)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (6)   
   Pfam (6)   
All databases (24)   

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