KEGG   Escherichia coli O44 H18 042 (EAEC): EC042_0670
Entry
EC042_0670        CDS       T02067                                 
Symbol
mrdA
Name
(GenBank) penicillin-binding protein 2
  KO
K05515  penicillin-binding protein 2 [EC:3.4.16.4]
Organism
elo  Escherichia coli O44:H18 042 (EAEC)
Pathway
elo00550  Peptidoglycan biosynthesis
elo01100  Metabolic pathways
elo01501  beta-Lactam resistance
Brite
KEGG Orthology (KO) [BR:elo00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    EC042_0670 (mrdA)
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01501 beta-Lactam resistance
    EC042_0670 (mrdA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01011 Peptidoglycan biosynthesis and degradation proteins [BR:elo01011]
    EC042_0670 (mrdA)
Enzymes [BR:elo01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.16  Serine-type carboxypeptidases
    3.4.16.4  serine-type D-Ala-D-Ala carboxypeptidase
     EC042_0670 (mrdA)
Peptidoglycan biosynthesis and degradation proteins [BR:elo01011]
 Peptidoglycan biosynthesis and degradation
  DD-Transpeptidase (Class B PBP)
   EC042_0670 (mrdA)
SSDB
Motif
Pfam: Transpeptidase PBP_dimer
Other DBs
NCBI-ProteinID: CBG33496
UniProt: D3GX98
Position
complement(742072..743973)
AA seq 633 aa
MKLQNSFRDYTAESALFVRRALVAFLGILLLTGVLIANLYNLQIVRFTDYQTRSNENRIK
LVPIAPSRGIIYDRNGIPLALNRTIYQIEMMPEKVDNVQQTLDALRSVVDLTDDDIAAFR
KERARSHRFTSIPVKTNLTEVQVARFAVNQYRFPGVEVKGYKRRYYPYGSALTHVIGYVS
KINDKDVERLNNDGKLANYAATHDIGKLGIERYYEDVLHGQTGYEEVEVNNRGRVIRQLK
EVPPQAGHDIYLTLDLKLQQYIETLLAGSRAAVVVTDPRTGGVLALVSTPSYDPNLFVDG
ISSKDYSALLNDPNTPLVNRATQGVYPPASTVKPYVAVSALSAGVITRNTTLFDPGWWQL
PGSEKRYRDWKKWGHGRLNVTRSLEESADTFFYQVAYDMGIDRLSEWMGKFGYGHYTGID
LAEERSGNMPTREWKQKRFKKPWYQGDTIPVGIGQGYWTATPIQMSKALMILINDGIVKV
PHLLMSTAEDGKQVPWVQPHEPPVGDIHSGYWELAKDGMYGVANRPNGTAHKYFASAPYK
IAAKSGTAQVFGLKANETYNAHKIAERLRDHKLMTAFAPYNNPQVAVAMILENGGAGPAV
GTLMRQILDHIMLGDNNTDLPAENPAVAAAEDH
NT seq 1902 nt   +upstreamnt  +downstreamnt
atgaaactacagaactcttttcgcgactatacggcagagtccgcgctgtttgtgcgccgg
gcgctggtcgcctttttggggattttgctgctgaccggcgtgcttatcgccaacctgtat
aatctgcaaattgttcgctttaccgattaccagacccgctctaatgaaaaccgcattaaa
ctggtgcctatcgcgcccagccgcggcattatctacgaccgtaacggtatccctctggca
cttaaccgcactatctaccagatagagatgatgccggagaaagtcgataacgtgcagcaa
acgctggacgctttgcgcagcgtggttgatctgaccgatgacgatattgctgcattccga
aaagagcgcgcacgttcacaccgtttcacctccattccggtgaaaactaacctgaccgaa
gtacaagtggcgcgctttgccgtcaatcagtaccgttttccgggtgttgaagttaaaggc
tataaacgtcgttactatccttacggttcggcgttgacccacgtcatcggctatgtgtcg
aaaatcaacgataaagacgtcgaacgcctgaataatgacggcaaactggccaactatgcg
gcaacgcatgatataggtaagctgggcattgagcgttactatgaagacgtgctgcacggt
cagactggttatgaagaggttgaagttaacaaccgtgggcgtgttatccgccagttaaaa
gaagtaccaccgcaagccggacacgatatttacctgacgctggatctcaaactccagcaa
tatattgaaacgctgctggcgggtagccgcgcagctgtggtagtcaccgatccgcgtaca
ggtggggtgctggcgctggtttccacgcctagttatgacccaaacctatttgttgacggt
atctccagcaaagattattccgccttgctgaacgacccgaatacaccgctggtgaaccgc
gccacacagggggtttatcctcccgcgtctacagttaaaccctatgtggcggtttcggca
ttgagcgccggagtgatcacgcgcaatacgacgctgtttgacccaggctggtggcaactg
ccaggttcggaaaaacgttatcgtgactggaaaaaatggggccacgggcgtctgaatgtc
acaagatcgctggaagaatctgcggataccttcttctatcaggtggcctacgatatggga
atcgatcgcctctccgaatggatgggtaaattcggttatggtcattacaccggtatcgac
ctggcggaagaacgttccggcaacatgcctacccgcgaatggaaacagaaacgctttaaa
aaaccgtggtatcagggtgacaccattccggttggtatcggtcagggttactggacagcg
accccaatccagatgagtaaggcactgatgatcctgattaatgacggtatcgtgaaggtt
ccgcatttgctgatgagcaccgccgaagacggcaaacaggtgccatgggtacaaccgcat
gaaccgcccgtcggcgatattcattccggttactgggagctggcaaaagacggtatgtac
ggtgttgctaaccgccctaacggtacggcgcataaatactttgccagcgcaccgtacaaa
attgcggcgaaatctggtacagctcaggtcttcggtctgaaagcgaacgaaacctataat
gcgcacaaaattgccgagcgtttacgtgaccacaaactgatgactgcctttgcgccatac
aacaatccgcaagtggctgtcgccatgattctggagaacggtggcgcgggtccagcggtt
ggtacgctgatgcgccagatcctcgaccacattatgctgggtgataacaacaccgatctg
cctgcggaaaatccagcggttgccgcagcggaggaccattaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (2)   
   Pfam (2)   
All databases (14)   

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