KEGG   Enterobacter kobei ENHKU01: ECENHK_03475
Entry
ECENHK_03475      CDS       T02315                                 
Symbol
thrA
Name
(GenBank) bifunctional aspartokinase I/homoserine dehydrogenase I
  KO
K12524  bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:2.7.2.4 1.1.1.3]
Organism
eno  Enterobacter kobei ENHKU01
Pathway
eno00260  Glycine, serine and threonine metabolism
eno00261  Monobactam biosynthesis
eno00270  Cysteine and methionine metabolism
eno00300  Lysine biosynthesis
eno01100  Metabolic pathways
eno01110  Biosynthesis of secondary metabolites
eno01120  Microbial metabolism in diverse environments
eno01230  Biosynthesis of amino acids
Module
eno_M00016  Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
eno_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
eno_M00018  Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:eno00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    ECENHK_03475 (thrA)
   00270 Cysteine and methionine metabolism
    ECENHK_03475 (thrA)
   00300 Lysine biosynthesis
    ECENHK_03475 (thrA)
  09110 Biosynthesis of other secondary metabolites
   00261 Monobactam biosynthesis
    ECENHK_03475 (thrA)
Enzymes [BR:eno01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.3  homoserine dehydrogenase
     ECENHK_03475 (thrA)
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.2  Phosphotransferases with a carboxy group as acceptor
    2.7.2.4  aspartate kinase
     ECENHK_03475 (thrA)
SSDB
Motif
Pfam: Homoserine_dh AA_kinase NAD_binding_3 ACT_7 ACT DUF6247
Other DBs
NCBI-ProteinID: AFP68584
UniProt: A0A2J0PP43
Position
740399..742861
AA seq 820 aa
MRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKITNHLVAMIEKTIGGQDA
LPNISDAERIFAELLQGLAEAQPGFPLAQLKSFVEQEFAQIKHVLHGISLLGQCPDSINA
ALICRGEKLSIAIMAGLLEARGHGVTVINPVEKLLAVGHYLESTVDIAESTRRIAASKIP
SDHMILMAGFTAGNEKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRQV
PDARLLKSMSYQEAMELSYFGAKVLHPRTISPIAQFQIPCLIKNTGNPQAPGTLIGASSD
EDGLPVKGISNLNNMAMFSVSGPGMKGMVGMAARVFAAMSRNGISVVLITQSSSEYSISF
CVPQADCLRARRALEEEFYLELKEELLEPLSIQERLAVISVVGDGMRTLRGISAKFFAAL
ARANINIVAIAQGSSERSISVVVDNDDATTGVRVVHQMLFNTDQVIELFLIGVGGVGGAL
LEQVKRQQAWLKKKHIDLRVCGIANSRALLTNVHGLNLENWQAGLEEAKEPFNLGRLIRL
VKEYHLLNPVIVDCTSNQAVADQYADFLREGFHVVTPNKKANTSSMDYYHQLRLAASKSR
RKFLYDTNVGAGLPVIENLQNLLNAGDELQRFSGILSGSLSFIFGKLDEGMSLSEATRAA
RELGYTEPDPRDDLSGMDVARKLLILVRETGRELELSDIVIEPVLPAEFDSSGDVSTFMA
NLPQLDDAFAARVAKARDEGKVLRYVGNIEEDGVCRVKIAEVDGNDPLYKVKNGENALAF
YSHYYQPLPLVLRGYGAGNDVTAAGVFADLLRTLSWKLGV
NT seq 2463 nt   +upstreamnt  +downstreamnt
atgcgagtgttgaagttcggcggtacatcagtggcaaatgcagaacgttttctgcgtgtt
gccgatatcctggagagcaacgccaggcaggggcaggttgcgaccgtgctctctgccccg
gcaaaaatcacgaaccatctggtggcgatgattgaaaaaaccatcggtggtcaggatgca
cttccgaacatcagcgacgccgagcgtatcttcgctgagctgctgcaggggctggcggag
gcacagcccggcttcccgctcgcacagctgaagtctttcgttgagcaggagtttgctcag
atcaaacatgtgctgcacggtatcagcctgctgggccagtgtccggacagcatcaacgcg
gcgctgatctgccgcggtgagaaactgtcaatcgccatcatggctggcctgctggaagcg
cgtggccacggcgtgaccgtcataaatccggttgaaaaactgcttgcggtgggccactac
ctcgaatctacagttgatattgccgaatcaacccgccgtatcgccgcgagcaaaatccct
tctgaccatatgatcctgatggcgggctttaccgccggaaatgagaagggcgagctggtg
gtgctgggccgtaacggctccgactactctgccgccgtgctggctgcctgtttacgcgca
gactgttgtgagatctggactgacgtcgacggcgtgtatacctgcgacccgcgccaggta
ccggacgccaggttgctgaagtcgatgtcttaccaggaagcgatggagctttcctacttc
ggcgccaaagtgcttcacccacgtaccatctccccgattgcccagttccagatcccttgc
ctgattaaaaacaccggtaacccgcaagcgccaggcacgctgattggtgccagctctgat
gaagatggcctgccggtgaaaggcatctccaacctcaataacatggcgatgttcagcgtc
tccggtccggggatgaagggcatggtcggcatggcggcgcgcgtatttgccgcaatgtca
cgcaacggtatctcggtggtgctgatcacgcagtcctcttccgagtacagcatcagcttc
tgcgtgccgcaggccgactgcctgcgcgcacgccgtgcgctggaagaagagttttatctg
gagctgaaagaggagttgctggagccgctctccattcaggagcgtctggccgtcatctcc
gtcgtgggcgacgggatgcgcaccctgcgcggtatctccgcaaagttctttgccgcgctg
gcccgcgccaacatcaatatcgtggcgattgcccagggctcgtctgagcgttctatctcc
gtcgtggtggataacgacgatgccaccaccggcgtgcgcgtggtgcatcagatgctgttc
aataccgatcaggtcattgaactgttcctgattggcgtgggcggtgtcggcggcgcgctg
cttgagcaggtgaagcgtcagcaggcgtggctcaagaagaagcatatcgatctgcgcgtc
tgcggtattgccaattccagagcgctactgaccaatgtgcatggtctgaatcttgaaaac
tggcaggccgggctggaagaggcgaaagagccgtttaatctgggtcgccttatccgtctg
gtaaaagagtaccatctgcttaacccggtgattgtcgactgtacgtcaaaccaggccgtt
gccgaccagtatgcggatttcctgcgcgaaggcttccacgtggtgacgccgaacaaaaag
gccaacacctcgtcgatggattactatcaccagctgcgtctggcggcgagcaagtcgcgc
cgtaagttcctgtacgacaccaacgtgggcgcaggcctgccggttatcgaaaatctgcaa
aatctgctgaatgcgggcgacgaactgcagcgcttctccggcattctctccggctccctg
tcgtttatctttggcaagctggacgagggcatgagcctctcggaagccacccgcgccgcg
cgcgagctgggctataccgagccggatccacgtgacgatctctccggcatggacgtggcg
cgtaagctgctgatcctcgtgcgcgaaaccggtcgcgagctggagctttcggacattgtg
attgaacccgtgttgccagccgagtttgacagcagcggtgatgtcagcacctttatggcg
aatttaccccagcttgacgatgcttttgccgcgcgcgtggcgaaagcccgtgatgaaggt
aaggtattgcgctatgttggcaacattgaagaagatggcgtgtgccgggtgaagattgcc
gaagtggatggcaacgatccgctgtacaaagtcaaaaacggcgaaaacgccctcgcgttt
tacagccactattatcagccattgccgctggtgcttcgcggctatggcgcagggaacgat
gtgacagcggcgggtgtgtttgccgatctgttgcgtaccctgtcatggaagttaggagtt
taa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (13)   
   KEGG PATHWAY (8)   
   KEGG MODULE (5)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (5)   
   KEGG ENZYME (2)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (6)   
   Pfam (6)   
All databases (42)   

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