KEGG   ENZYME: 1.1.1.10Help
Entry
EC 1.1.1.10                 Enzyme                                 

Name
L-xylulose reductase;
xylitol dehydrogenase (ambiguous)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
xylitol:NADP+ 4-oxidoreductase (L-xylulose-forming)
Reaction(IUBMB)
xylitol + NADP+ = L-xylulose + NADPH + H+ [RN:R01904]
Reaction(KEGG)
Substrate
xylitol [CPD:C00379];
NADP+ [CPD:C00006]
Product
L-xylulose [CPD:C00312];
NADPH [CPD:C00005];
H+ [CPD:C00080]
History
EC 1.1.1.10 created 1961
Pathway
Pentose and glucuronate interconversions
Metabolic pathways
Orthology
K03331  
L-xylulose reductase
Genes
HSA: 
51181(DCXR)
PTR: 
454983(DCXR)
PPS: 
100986866(DCXR)
GGO: 
101147323(DCXR)
PON: 
100451797(DCXR)
MCC: 
715513(DCXR)
MCF: 
MMU: 
67880(Dcxr)
RNO: 
171408(Dcxr)
CGE: 
100769825(Dcxr)
HGL: 
101724611(Dcxr)
TUP: 
102494322(DCXR)
CFA: 
475926(DCXR)
AML: 
FCA: 
101091167(DCXR)
PTG: 
102955790(DCXR)
BTA: 
BOM: 
PHD: 
CHX: 
CFR: 
102506249(DCXR)
BACU: 
103019514(DCXR)
LVE: 
103079231(DCXR)
ECB: 
100147313(DCXR)
MYB: 
102249804(DCXR)
MYD: 
102760861(DCXR)
PALE: 
102879907(DCXR)
MDO: 
100029860(DCXR)
SHR: 
100918900(DCXR)
OAA: 
100088137(DCXR)
GGA: 
374066(DCXR)
MGP: 
TGU: 
FAB: 
PHI: 
APLA: 
FCH: 
CLV: 
ASN: 
AMJ: 
PSS: 
CMY: 
ACS: 
PBI: 
XLA: 
734498(dcxr)
XTR: 
394704(dcxr)
DRE: 
550282(dcxr)
TRU: 
MZE: 
XMA: 
LCM: 
102364327(DCXR)
CMK: 
BFO: 
CIN: 
SPU: 
DME: 
DPO: 
DAN: 
DER: 
DPE: 
DSE: 
DSI: 
DWI: 
DYA: 
DGR: 
DMO: 
DVI: 
AGA: 
AAG: 
CQU: 
AME: 
413567(GB18760)
NVI: 
TCA: 
BMOR: 
API: 
PHU: 
ISC: 
CEL: 
CBR: 
CBG08572(Cbr-dhs-21)
NVE: 
AQU: 
BPD: 
 » show all
Taxonomy
Reference
1  [PMID:2981816]
  Authors
Doten RC, Mortlock RP.
  Title
Characterization of xylitol-utilizing mutants of Erwinia uredovora.
  Journal
J. Bacteriol. 161 (1985) 529-33.
  Organism
Erwinia uredovora
Reference
2  [PMID:13654257]
  Authors
HICKMAN J, ASHWELL G.
  Title
A sensitive and stereospecific enzymatic assay for xylulose.
  Journal
J. Biol. Chem. 234 (1959) 758-61.
  Organism
Cavia porcellus
Reference
3  [PMID:13416220]
  Authors
HOLLMANN S, TOUSTER O.
  Title
The L-xylulose-xylitol enzyme and other polyol dehydrogenases of guinea pig liver mitochondria.
  Journal
J. Biol. Chem. 225 (1957) 87-102.
  Organism
Cavia porcellus
Reference
4  [PMID:13357463]
  Authors
HUTCHESON RM, REYNOLDS VH, TOUSTER O.
  Title
The reduction of L-xylulose to xylitol by guinea pig liver mitochondria.
  Journal
J. Biol. Chem. 221 (1956) 697-709.
  Organism
Cavia porcellus
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9028-17-5

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