KEGG   ENZYME: 1.1.1.10Help
Entry
EC 1.1.1.10                 Enzyme                                 
Name
L-xylulose reductase;
xylitol dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
xylitol:NADP+ 4-oxidoreductase (L-xylulose-forming)
Reaction(IUBMB)
xylitol + NADP+ = L-xylulose + NADPH + H+ [RN:R01904]
Reaction(KEGG)
Substrate
xylitol [CPD:C00379];
NADP+ [CPD:C00006]
Product
L-xylulose [CPD:C00312];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Pathway
Pentose and glucuronate interconversions
Metabolic pathways
Orthology
K03331  
L-xylulose reductase
Genes
HSA: 
51181(DCXR)
PTR: 
454983(DCXR)
PPS: 
100986866(DCXR)
GGO: 
101147323(DCXR)
PON: 
100451797(DCXR)
MCC: 
715513(DCXR)
MMU: 
67880(Dcxr)
RNO: 
171408(Dcxr)
CFA: 
475926(DCXR)
AML: 
FCA: 
101091167(DCXR)
BTA: 
100852322 526937(DCXR)
ECB: 
100147313
MDO: 
100029860
SHR: 
100918900(DCXR)
OAA: 
100088137
GGA: 
374066(DCXR)
MGP: 
100542961
TGU: 
100223059
ACS: 
100564046
XLA: 
734498(dcxr)
XTR: 
394704(dcxr)
DRE: 
550282(dcxr)
TRU: 
101064368
BFO: 
BRAFLDRAFT_200527
SPU: 
591319 764309
DME: 
Dmel_CG7322
DPO: 
Dpse_GA20258
DAN: 
Dana_GF19246
DER: 
Dere_GG18088
DPE: 
Dper_GL21318
DSE: 
Dsec_GM22780
DSI: 
Dsim_GD24467
DWI: 
Dwil_GK20088
DYA: 
Dyak_GE15485
DGR: 
Dgri_GH17658
DMO: 
Dmoj_GI21510
DVI: 
Dvir_GJ19048
AGA: 
AgaP_AGAP008502
AAG: 
AaeL_AAEL014798
CQU: 
CpipJ_CPIJ000372
AME: 
413567
NVI: 
100114175(NV17556)
TCA: 
659735
API: 
100144913 100145846(Dcxr) 100165603 100166350 100169170
PHU: 
Phum_PHUM055310
ISC: 
IscW_ISCW020246
CEL: 
CELE_R11D1.11(dhs-21)
CBR: 
CBG08572(Cbr-dhs-21)
NVE: 
NEMVE_v1g114632
AQU: 
100635980
BPD: 
BURPS668_1913
MSM: 
MSMEG_3262
 » show all
Taxonomy
Reference
1  [PMID:2981816]
  Authors
Doten RC, Mortlock RP.
  Title
Characterization of xylitol-utilizing mutants of Erwinia uredovora.
  Journal
J. Bacteriol. 161 (1985) 529-33.
  Organism
Erwinia uredovora
Reference
2  [PMID:13654257]
  Authors
HICKMAN J, ASHWELL G.
  Title
A sensitive and stereospecific enzymatic assay for xylulose.
  Journal
J. Biol. Chem. 234 (1959) 758-61.
  Organism
Cavia porcellus
Reference
3  [PMID:13416220]
  Authors
HOLLMANN S, TOUSTER O.
  Title
The L-xylulose-xylitol enzyme and other polyol dehydrogenases of guinea pig liver mitochondria.
  Journal
J. Biol. Chem. 225 (1957) 87-102.
  Organism
Cavia porcellus
Reference
4  [PMID:13357463]
  Authors
HUTCHESON RM, REYNOLDS VH, TOUSTER O.
  Title
The reduction of L-xylulose to xylitol by guinea pig liver mitochondria.
  Journal
J. Biol. Chem. 221 (1956) 697-709.
  Organism
Cavia porcellus
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
9028-17-5
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