KEGG   ENZYME: 1.1.1.140Help
Entry
EC 1.1.1.140                Enzyme                                 
Name sorbitol-6-phosphate 2-dehydrogenase;
ketosephosphate reductase;
ketosephosphate reductase;
D-sorbitol 6-phosphate dehydrogenase;
D-sorbitol-6-phosphate dehydrogenase;
sorbitol-6-P-dehydrogenase;
D-glucitol-6-phosphate dehydrogenase
Class Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname D-sorbitol-6-phosphate:NAD+ 2-oxidoreductase
Reaction(IUBMB) D-sorbitol 6-phosphate + NAD+ = D-fructose 6-phosphate + NADH + H+
[RN:R07133]
Reaction(KEGG) R07133 > R05607
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Substrate D-sorbitol 6-phosphate [CPD:C01096];
NAD+ [CPD:C00003]
Product D-fructose 6-phosphate [CPD:C00085];
NADH [CPD:C00004];
H+ [CPD:C00080]
Pathway PATH: ec00051  Fructose and mannose metabolism
Orthology KO: K00068  sorbitol-6-phosphate 2-dehydrogenase
Genes ECO: b2705(srlD)
ECJ: JW2674(srlD)
ECD: ECDH10B_2873(srlD)
EBW: BWG_2441(srlD)
ECE: Z4012(srlD) Z5618
ECS: ECs3561 ECs5003
ECF: ECH74115_3955(srlD) ECH74115_5498
ETW: ECSP_3653(srlD) ECSP_5096
ECG: E2348C_4335
ECC: c3259(srlD) c4986
ECI: UTI89_C3067(srlD) UTI89_C4588
ECP: ECP_2665 ECP_4238
ECV: APECO1_2448 APECO1_3821(srlD)
ECW: EcE24377A_2989(srlD)
ECX: EcHS_A2841(srlD)
ECM: EcSMS35_2828(srlD) EcSMS35_4481
ECY: ECSE_2953
ECL: EcolC_1007
ECK: EC55989_2967(srlD)
ECQ: ECED1_3154(srlD) ECED1_4735
ECR: ECIAI1_2797(srlD)
ECT: ECIAI39_2891(srlD) ECIAI39_4417
ECZ: ECS88_2968(srlD) ECS88_4493
EUM: ECUMN_3026(srlD) ECUMN_4553
ELF: LF82_2172(srlD) LF82_p637
EBL: B21_02520(srlD)
EBD: ECBD_1020
EBR: ECB_02555(srlD)
EOH: ECO103_3240(srlD)
EOI: ECO111_3423(srlD) ECO111_4839
EOJ: ECO26_3768(srlD) ECO26_5132
EFE: EFER_4082
STY: STY2956(srlD)
STT: t2736(srlD)
SPT: SPA2693(srlD)
SEK: SSPA2507
SPQ: SPAB_03525
SEI: SPC_2876(srlD)
SEC: SC2768(srlD)
SEH: SeHA_C3021(srlD)
SEE: SNSL254_A3037(srlD)
SEW: SeSA_A2986(srlD)
SEA: SeAg_B2955(srlD)
SED: SeD_A3144(srlD)
SEG: SG2738(srlD)
SET: SEN2676(srlD)
SES: SARI_00137
STM: STM2835(srlD)
YEN: YE1095(gutD)
SFL: SF2728(srlD) SF4093(sorD)
SFX: S2919(srlD) S3637(sorD)
SFV: SFV_2800(srlD) SFV_4098(sorD)
SSN: SSON_4198(sorD)
SBO: SBO_2813(srlD) SBO_4048(sorD)
SBC: SbBS512_E3172(srlD) SbBS512_E4523
SDY: SDY_2902(srlD)
KPN: KPN_03040(srlD) KPN_04407
KPE: KPK_1086(srlD) KPK_5267(sorD)
KPU: KP1_4304(srlD)
CKO: CKO_04059
SPE: Spro_3572
HSO: HS_0676(srlD)
HSM: HSM_1085
PMU: PM1968
ASU: Asuc_0437
ASA: ASA_3580(srlD)
TAU: Tola_0245
CVI: CV_2258
BLI: BL02488
BLD: BLi03863
BCL: ABC1160
SCA: Sca_2317(srlD)
SMU: SMU.308
SEQ: SZO_01750(sorD)
SEZ: Sez_0204(sorD)
SUB: SUB1705(sorD)
LPL: lp_3623(srlD1) lp_3657(srlD2)
LPJ: JDM1_2925(srlD2)
LSL: LSL_1894
LCA: LSEI_2729
LCB: LCABL_04240(sorF) LCABL_29060(gutF)
LRH: LGG_00342(gutF) LGG_02722(gutF)
LRL: LC705_00407(sorF) LC705_02725(gutF)
EFA: EF3310
CDF: CD0768(gutD)
CDC: CD196_0715(gutD)
CDL: CDR20291_0696(gutD)
CBO: CBO3413(gutD)
CBA: CLB_3470(srlD)
CBH: CLC_3358(srlD)
CBY: CLM_3879(srlD)
CBL: CLK_2856(srlD)
CBK: CLL_A0401
CBB: CLD_1093(srlD)
CBI: CLJ_B3720(srlD)
CBT: CLH_0387
CBF: CLI_3596(srlD)
CBE: Cbei_0340
ATE: Athe_0698
CSC: Csac_0868
MMY: MSC_0020(srlD)
MCP: MCAP_0029
STR: Sterm_1063 Sterm_1991
DTH: DICTH_0305
DTU: Dtur_0422
HMA: rrnAC0917(sorD)
Taxonomy
Reference
  Authors
  Title

  Journal
  Organism
 1  [PMID:4318899]
Du Toit PJ, Kotze JP.
The isolation and characterization of sorbitol-6-phosphate
dehydrogenase from Clostridium pasteurianum.
Biochim. Biophys. Acta. 206 (1970) 333-42.
Clostridium pasteurianum
Reference
  Authors
  Title

  Journal
  Organism
 2  [PMID:14465816]
LISS M, HORWITZ SB, KAPLAN NO.
D-Mannitol 1-phosphate dehydrogenase and D-sorbitol 6-phosphate
dehydrogenase in Aerobacter aerogenes.
J. Biol. Chem. 237 (1962) 1342-50.
Klebsiella pneumoniae [GN:kpn]
Other DBs ExplorEnz - The Enzyme Database: 1.1.1.140
IUBMB Enzyme Nomenclature: 1.1.1.140
ExPASy - ENZYME nomenclature database: 1.1.1.140
BRENDA, the Enzyme Database: 1.1.1.140
CAS: 37250-69-4
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