| Entry |
|
|---|
| Name |
3alpha-hydroxy-5beta-androstane-17-one 3alpha-dehydrogenase;
etiocholanolone 3alpha-dehydrogenase;
etiocholanolone 3alpha-dehydrogenase;
3alpha-hydroxy-5beta-steroid dehydrogenase |
|---|
| Class |
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
 |
|---|
| Sysname |
3alpha-hydroxy-5beta-steroid:NAD+ 3-oxidoreductase |
|---|
| Reaction(IUBMB) |
3alpha-hydroxy-5beta-androstane-17-one + NAD+ =
5beta-androstane-3,17-dione + NADH + H+ [RN:R04309] |
|---|
| Reaction(KEGG) |
R04309
 |
|---|
| Substrate |
3alpha-hydroxy-5beta-androstane-17-one;
NAD+ [CPD:C00003] |
|---|
| Product |
5beta-androstane-3,17-dione [CPD:C03772];
NADH [CPD:C00004];
H+ [CPD:C00080] |
|---|
| Pathway |
PATH: ec00140 Steroid hormone biosynthesis |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:5365796]
Roe CR, Kaplan NO.
Purification and substrate specificities of bacterial hydroxysteroid
dehydrogenases.
Biochemistry. 8 (1969) 5093-103.
Pseudomonas testosteroni |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 1.1.1.152
IUBMB Enzyme Nomenclature: 1.1.1.152
ExPASy - ENZYME nomenclature database: 1.1.1.152
BRENDA, the Enzyme Database: 1.1.1.152
CAS: 37250-77-4 |
|---|
