| Entry |
|
| Name |
cholestanetetraol 26-dehydrogenase;
cholestanetetrol 26-dehydrogenase;
5beta-cholestane-3alpha,7alpha,12alpha,26-tetrol dehydrogenase;
TEHC-NAD oxidoreductase;
5beta-cholestane-3alpha,7alpha,12alpha,26-tetraol:NAD+
26-oxidoreductase |
| Class |
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
 |
| Sysname |
(25R)-5beta-cholestane-3alpha,7alpha,12alpha,26-tetraol:NAD+
26-oxidoreductase |
| Reaction(IUBMB) |
(25R)-5beta-cholestane-3alpha,7alpha,12alpha,26-tetraol + NAD+ =
(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al + NADH
+ H+ [RN:R03507] |
| Reaction(KEGG) |
R03507
 |
| Substrate |
(25R)-5beta-cholestane-3alpha,7alpha,12alpha,26-tetraol;
NAD+ [CPD:C00003] |
| Product |
(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-al;
NADH [CPD:C00004];
H+ [CPD:C00080] |
Reference Authors Title
Journal Organism
|
1 [PMID:5914340]
Masui T, Herman R, Staple E.
The oxidation of 5-beta-cholestane-3-alpha, 7-alpha, 12-alpha,
26-tetraol to 5-beta-cholestane-3-alpha, 7-alpha,
12-alpha-triol-26-oic acid via 5-beta-cholestane-3-alpha, 7-alpha,
12-alpha-triol-26-al by rat liver.
Biochim. Biophys. Acta. 117 (1966) 266-8.
Rattus norvegicus [GN:rno] |
| Other DBs |
ExplorEnz - The Enzyme Database: 1.1.1.161
IUBMB Enzyme Nomenclature: 1.1.1.161
ExPASy - ENZYME nomenclature database: 1.1.1.161
BRENDA, the Enzyme Database: 1.1.1.161
CAS: 62213-60-9 |
|