| Entry |
|
|---|
| Name |
glucuronate reductase;
aldehyde reductase;
L-hexonate:NADP dehydrogenase;
TPN-L-gulonate dehydrogenase;
aldehyde reductase II;
NADP-L-gulonate dehydrogenase;
D-glucuronate dehydrogenase;
D-glucuronate reductase;
L-glucuronate reductase (incorrect) |
|---|
| Class |
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
 |
|---|
| Sysname |
L-gulonate:NADP+ 6-oxidoreductase |
|---|
| Reaction(IUBMB) |
L-gulonate + NADP+ = D-glucuronate + NADPH + H+ [RN:R01481] |
|---|
| Reaction(KEGG) |
R01481
 |
|---|
| Substrate |
L-gulonate [CPD:C00800];
NADP+ [CPD:C00006] |
|---|
| Product |
D-glucuronate [CPD:C00191];
NADPH [CPD:C00005];
H+ [CPD:C00080] |
|---|
| Comment |
Also reduces D-galacturonate. May be identical with EC 1.1.1.2
[alcohol dehydrogenase (NADP+)]. |
|---|
| Pathway |
PATH: ec00040 Pentose and glucuronate interconversions
PATH: ec00053 Ascorbate and aldarate metabolism
PATH: ec01100 Metabolic pathways |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:13913518]
SIVAK A, HOFFMANN-OSTENHOF O.
Enzymes of mesoinositol catabolism in the yeast Schwanniomyces
accidentalis.
Biochim. Biophys. Acta. 53 (1961) 426-8.
Schwanniomyces occidentalis |
|---|
Reference
Authors
Title
Journal
|
2
von Wartburg, J.P. and Wermoth, B.
Aldehyde reductase.
In: Jakoby, W.B. (Ed.), Enzymatic Basis of Detoxication, vol. 1,
Academic Press, New York, 1980, p. 249-260. |
|---|
Reference
Authors
Title
Journal
Organism
|
3 [PMID:13787380]
YORK JL, GROLLMAN AP, BUBLITZ C.
TPN-L-gluonate dehydrogenase.
Biochim. Biophys. Acta. 47 (1961) 298-306.
Rattus norvegicus [GN:rno], Sus scofa [GN:ssc] |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 1.1.1.19
IUBMB Enzyme Nomenclature: 1.1.1.19
ExPASy - ENZYME nomenclature database: 1.1.1.19
BRENDA, the Enzyme Database: 1.1.1.19
CAS: 9028-29-9 |
|---|
