| Entry |
|
|---|
| Name |
glucuronolactone reductase;
GRase;
gulonolactone dehydrogenase |
|---|
| Class |
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
 |
|---|
| Sysname |
L-gulono-1,4-lactone:NADP+ 1-oxidoreductase |
|---|
| Reaction(IUBMB) |
L-gulono-1,4-lactone + NADP+ = D-glucurono-3,6-lactone + NADPH + H+
[RN:R03183] |
|---|
| Reaction(KEGG) |
R03183
 |
|---|
| Substrate |
L-gulono-1,4-lactone [CPD:C01040];
NADP+ [CPD:C00006] |
|---|
| Product |
D-glucurono-3,6-lactone [CPD:C02670];
NADPH [CPD:C00005];
H+ [CPD:C00080] |
|---|
| Pathway |
PATH: ec00053 Ascorbate and aldarate metabolism |
|---|
Reference
Authors
Title
Journal
|
1
Suzuki, K., Mano, Y. and Shimazono, N.
Conversion of L-gulonolactone to L-ascorbic acid; properties of the
microsomal enzyme in rat liver.
J. Biochem. (Tokyo) 48 (1960) 313-315. |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 1.1.1.20
IUBMB Enzyme Nomenclature: 1.1.1.20
ExPASy - ENZYME nomenclature database: 1.1.1.20
BRENDA, the Enzyme Database: 1.1.1.20
CAS: 9028-30-2 |
|---|
