| Entry |
|
|---|
| Name |
quinate dehydrogenase;
quinic dehydrogenase;
quinate:NAD oxidoreductase;
quinate 5-dehydrogenase;
quinate:NAD+ 5-oxidoreductase |
|---|
| Class |
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
 |
|---|
| Sysname |
L-quinate:NAD+ 3-oxidoreductase |
|---|
| Reaction(IUBMB) |
L-quinate + NAD+ = 3-dehydroquinate + NADH + H+ [RN:R01872] |
|---|
| Reaction(KEGG) |
R01872
 |
|---|
| Substrate |
L-quinate [CPD:C00296];
NAD+ [CPD:C00003] |
|---|
| Product |
3-dehydroquinate [CPD:C00944];
NADH [CPD:C00004];
H+ [CPD:C00080] |
|---|
| Comment |
The enzyme is specific for quinate as substrate; phenylpyruvate,
phenylalanine, cinnamate and shikimate will not act as substrates.
NAD+ cannot be replaced by NADP+. |
|---|
| Pathway |
PATH: ec00400 Phenylalanine, tyrosine and tryptophan biosynthesis |
|---|
| Orthology |
KO: K09484 quinate dehydrogenase |
|---|
| Genes |
DHA: DEHA0C04224g
NCR: NCU06025
MGR: MGG_07781
ANI: AN1137.2
AFM: AFUA_1G11590
AOR: AO090038000263
ANG: An03g03710
 |
|---|
Reference
Authors
Title
Journal
|
1
Gamborg, O.L.
Aromatic metabolism in plants. III. Quinate dehydrogenase from mung
bean cell suspension cultures.
Biochim. Biophys. Acta 128 (1966) 483-491. |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:13208693]
MITSUHASHI S, DAVIS BD.
Aromatic biosynthesis. XIII. Conversion of quinic acid to
5-dehydroquinic acid by quinic dehydrogenase.
Biochim. Biophys. Acta. 15 (1954) 268-80.
Klebsiella pneumoniae [GN:kpn] |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 1.1.1.24
IUBMB Enzyme Nomenclature: 1.1.1.24
ExPASy - ENZYME nomenclature database: 1.1.1.24
BRENDA, the Enzyme Database: 1.1.1.24
CAS: 9028-28-8 |
|---|
