| Entry |
|
|---|
| Name |
shikimate dehydrogenase;
dehydroshikimic reductase;
shikimate oxidoreductase;
shikimate:NADP+ oxidoreductase;
5-dehydroshikimate reductase;
shikimate 5-dehydrogenase;
5-dehydroshikimic reductase;
DHS reductase;
shikimate:NADP+ 5-oxidoreductase;
AroE |
|---|
| Class |
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
 |
|---|
| Sysname |
shikimate:NADP+ 3-oxidoreductase |
|---|
| Reaction(IUBMB) |
shikimate + NADP+ = 3-dehydroshikimate + NADPH + H+ [RN:R02413] |
|---|
| Reaction(KEGG) |
R02413
 |
|---|
| Substrate |
shikimate [CPD:C00493];
NADP+ [CPD:C00006] |
|---|
| Product |
3-dehydroshikimate [CPD:C02637];
NADPH [CPD:C00005];
H+ [CPD:C00080] |
|---|
| Comment |
NAD+ cannot replace NADP+ [3]. In higher organisms, this enzyme
forms part of a multienzyme complex with EC 4.2.1.10,
3-dehydroquinate dehydratase [4]. |
|---|
| Pathway |
PATH: ec00400 Phenylalanine, tyrosine and tryptophan biosynthesis
PATH: ec01061 Biosynthesis of phenylpropanoids
PATH: ec01063 Biosynthesis of alkaloids derived from shikimate
pathway
PATH: ec01070 Biosynthesis of plant hormones
PATH: ec01100 Metabolic pathways |
|---|
| Orthology |
KO: K00014 shikimate 5-dehydrogenase |
|---|
| Genes |
ATH: AT3G06350(MEE32)
OSA: 4325444(Os01g0375200)
CME: CMK269C
SCE: YDR127W(ARO1)
AGO: AGOS_AGR066W
KLA: KLLA0F19712g
DHA: DEHA0E16247g
CAL: CaO19.4704(ARO1)
CGR: CAGL0M11484g
YLI: YALI0F12639g
SPO: SPAC1834.02(aro1)
MGR: MGG_01128
FGR: FG03880.1
AFM: AFUA_1G13740 AFUA_3G14790 AFUA_3G14800
AOR: AO090012000502
AFV: AFLA_008070
NFI: NFIA_062460 NFIA_062470
CNE: CNB01990
UMA: UM03607.1
ECO: b3281(aroE)
ECJ: JW3242(aroE)
ECD: ECDH10B_3456(aroE)
EBW: BWG_2972(aroE)
ECE: Z4652(aroE)
ECS: ECs4147(aroE)
ECF: ECH74115_4604(aroE)
ETW: ECSP_4252(aroE)
ECG: E2348C_3544(aroE)
ECC: c4042(aroE)
ECI: UTI89_C3726(aroE)
ECP: ECP_3369(aroE)
ECV: APECO1_3165(aroE)
ECW: EcE24377A_3764(aroE)
ECX: EcHS_A3475(aroE)
ECM: EcSMS35_3577(aroE) EcSMS35_4475
ECY: ECSE_3556(aroE)
ECL: EcolC_0432(aroE)
ECK: EC55989_3698(aroE)
ECQ: ECED1_3945(aroE)
ECR: ECIAI1_3431(aroE)
ECT: ECIAI39_3775(aroE) ECIAI39_4411
ECZ: ECS88_3669(aroE)
EUM: ECUMN_3755(aroE)
ELF: LF82_0144(aroE)
EBL: B21_03083(aroE)
EBD: ECBD_0470
EBR: ECB_03132(aroE)
EOH: ECO103_4013(aroE)
EOI: ECO111_4101(aroE)
EOJ: ECO26_4383(aroE)
EFE: EFER_0091(aroE) EFER_2592 EFER_3265(aroE)
STY: STY3924(aroE) STY4396(aroE)
STT: t3664(aroE) t4103(aroE)
SPT: SPA3268(aroE)
SEK: SSPA3047(aroE)
SPQ: SPAB_04242(aroE) SPAB_04800
SEI: SPC_3470(aroE) SPC_3944(aroE)
SEC: SC3337(aroE) SC3772(aroE)
SEH: SeHA_C3705(aroE) SeHA_C4190
SEE: SNSL254_A3670(aroE) SNSL254_A4140
SEW: SeSA_A3598(aroE) SeSA_A4068
SEA: SeAg_B3597(aroE) SeAg_B4084
SED: SeD_A3768(aroE) SeD_A4248
SEG: SG3574 SG4038(aroE)
SET: SEN3229(aroE) SEN3673
SES: SARI_04226(aroE)
STM: STM3401(aroE) STM3859(aroE)
YPE: YPO0246(aroE) YPO1610(aroE)
YPK: y1769(aroE) y4028(aroE)
YPM: YP_0245(aroE) YP_2244(aroE)
YPA: YPA_1912 YPA_3226(aroE)
YPN: YPN_2019 YPN_3822(aroE)
YPG: YpAngola_A0622(aroE)
YPP: YPDSF_0169(aroE) YPDSF_1837
YPS: YPTB2454(aroE) YPTB3660(aroE)
YPI: YpsIP31758_1587 YpsIP31758_3877(aroE)
YPY: YPK_0321(aroE) YPK_1695
YPB: YPTS_2538 YPTS_3852(aroE)
YEN: YE1700 YE3884(aroE)
SFL: SF3313(aroE)
SFX: S3537(aroE)
SFV: SFV_3302(aroE)
SSN: SSON_3422(aroE)
SBO: SBO_3275(aroE)
SBC: SbBS512_E3666(aroE)
SDY: SDY_3458(aroE)
ECA: ECA3995(aroE)
PCT: PC1_3784
PWA: Pecwa_3963
ETA: ETA_25900 ETA_31230(aroE)
PLU: plu4691(aroE)
PAY: PAU_04173(aroE)
BUC: BU493(aroE)
BAS: BUsg474(aroE)
BAB: bbp437(aroE)
BCC: BCc_312(aroE)
BAP: BUAP5A_486(aroE)
BAU: BUAPTUC7_487(aroE)
SGL: SG2242(aroE)
ENT: Ent638_3713(aroE)
ESA: ESA_00044(aroE)
CTU: Ctu_38090(aroE)
KPN: KPN_00075(aroE) KPN_00387 KPN_02128 KPN_03682(aroE) KPN_04401
KPE: KPK_0434(aroE) KPK_2195 KPK_4297 KPK_4667(aroE) KPK_5273
KPU: KP1_0890(aroE) KP1_1255 KP1_3223 KP1_5000(aroE)
CKO: CKO_04694(aroE)
SPE: Spro_4506(aroE)
PMR: PMI3292(aroE)
EIC: NT01EI_3347 NT01EI_3555
ETR: ETAE_2934(aroE1) ETAE_3194(aroE2)
BFL: Bfl221(aroE)
BPN: BPEN_228(aroE)
HDE: HDEF_1254(aroE)
DDA: Dd703_0444
DDC: Dd586_3698
DZE: Dd1591_0361
HIN: HI0607(aroE) HI0655(aroE)
HIT: NTHI0776(aroE) NTHI0862(aroE)
HIP: CGSHiEE_02010 CGSHiEE_08920(aroE)
HIQ: CGSHiGG_06560(aroE) CGSHiGG_06975
HDU: HD0415(aroE)
HAP: HAPS_1181(aroE) HAPS_1936(aroE)
HSO: HS_0006(aroE)
HSM: HSM_1897(aroE)
PMU: PM1271(aroE) PM1429(aroE)
MSU: MS0133(aroE) MS2315(aroE)
APL: APL_1139(aroE)
APJ: APJL_1158(aroE)
APA: APP7_1197(aroE)
ASU: Asuc_0337(aroE)
AAP: NT05HA_1165 NT05HA_2300
AAT: D11S_0227 D11S_1096
XFA: XF0624(aroE)
XFT: PD1532(aroE)
XFM: Xfasm12_1685(aroE)
XFN: XfasM23_1617(aroE)
XCC: XCC3953(aroE)
XCB: XC_4041(aroE)
XCA: xccb100_4141(aroE)
XCV: XCV4126(aroE)
XAC: XAC4034(aroE)
XOO: XOO4712(aroE)
XOM: XOO_0372(aroE)
XOP: PXO_02821(aroE)
SML: Smlt4495(aroE)
SMT: Smal_3856(aroE)
VCH: VC0056(aroE)
VCO: VC0395_A2464(aroE)
VCM: VCM66_0056(aroE)
VCJ: VCD_001524
VVU: VV1_1057(aroE)
VVY: VV3215(aroE)
VPA: VP3033(aroE)
VHA: VIBHAR_00382(aroE)
VSP: VS_3117(aroE)
VEX: VEA_002067
VFI: VF_2535(aroE)
VFM: VFMJ11_2666(aroE)
VSA: VSAL_I0083(aroE)
PPR: PBPRA3571(aroE)
PAE: PA0025(aroE) PA0244
PAU: PA14_00290(aroE) PA14_03020(aroE)
PAP: PSPA7_0026(aroE) PSPA7_0329
PAG: PLES_00241(aroE) PLES_02411
PPU: PP_0074(aroE) PP_2406(aroE) PP_2608 PP_3002(aroE-2)
PP_3768(aroE)
PPF: Pput_0090(aroE) Pput_1995 Pput_2691 Pput_3117 Pput_3289
PPG: PputGB1_0090(aroE) PputGB1_2040 PputGB1_2135 PputGB1_3217
PPW: PputW619_0093(aroE) PputW619_1912 PputW619_2099 PputW619_2153
PST: PSPTO_0169(aroE) PSPTO_2348 PSPTO_2685
PSB: Psyr_0025(aroE) Psyr_2132(aroE) Psyr_2418(aroE)
PSP: PSPPH_0027(aroE) PSPPH_2107 PSPPH_2576
PFL: PFL_0028(aroE) PFL_4005(aroE) PFL_5382(aroE)
PFO: Pfl01_0023(aroE) Pfl01_3713(aroE) Pfl01_4903(aroE)
PFS: PFLU0024(aroE) PFLU2134 PFLU5365(aroE)
PEN: PSEEN0031(aroE) PSEEN2020 PSEEN3214
PMY: Pmen_0061(aroE)
PSA: PST_0027(aroE)
CJA: CJA_3588(aroE)
AVN: Avin_00230(aroE) Avin_03620 Avin_20210 Avin_38080 Avin_46700
PAR: Psyc_0139(aroE)
PCR: Pcryo_0150
PRW: PsycPRwf_0119
ACI: ACIAD0418(aroE)
ACB: A1S_3109(aroE)
ABM: ABSDF0386(aroE)
ABY: ABAYE0377(aroE)
ABC: ACICU_03310(aroE)
ABN: AB57_3561(aroE)
ABB: ABBFA_000402(aroE)
SON: SO_0040(aroE)
SDN: Sden_0034(aroE)
SFR: Sfri_0034(aroE)
SAZ: Sama_0052
SBL: Sbal_0040(aroE)
SBM: Shew185_0035(aroE)
SBN: Sbal195_0039(aroE)
SBP: Sbal223_0039(aroE)
SLO: Shew_3727(aroE)
SPC: Sputcn32_0032(aroE)
SSE: Ssed_0043
SPL: Spea_0040
SHE: Shewmr4_0037(aroE)
SHM: Shewmr7_0035(aroE)
SHN: Shewana3_0043(aroE)
SHW: Sputw3181_0032(aroE)
SHL: Shal_0035
SWD: Swoo_0047
SWP: swp_0066
ILO: IL0024(aroE)
CPS: CPS_0030(aroE)
PHA: PSHAa0031(aroE)
PAT: Patl_0031
SDE: Sde_0026
MAQ: Maqu_0048(aroE)
AMC: MADE_00031
PIN: Ping_0071(aroE) Ping_3002
TTU: TERTU_0043(aroE)
CBU: CBU_0010(aroE)
CBS: COXBURSA331_A2191(aroE)
CBD: CBUD_0135(aroE)
CBG: CbuG_0279(aroE)
CBC: CbuK_0199(aroE)
LPN: lpg2808(aroE)
LPF: lpl2723(aroE)
LPP: lpp2854(aroE)
LPC: LPC_3094(aroE)
MCA: MCA2794(aroE)
FTU: FTT_0238(aroE1) FTT_0411c(aroE2)
FTF: FTF0238(aroE1) FTF0411c(aroE2)
FTW: FTW_1662 FTW_1853
FTL: FTL_0173 FTL_0481
FTH: FTH_0167(aroE1) FTH_0479(aroE2)
FTA: FTA_0189(aroE) FTA_0507
FTM: FTM_0567 FTM_1611
FTN: FTN_0078(aroE) FTN_0511
FPH: Fphi_0330 Fphi_0755
TCX: Tcr_0153
NOC: Noc_2575
AEH: Mlg_2825
HHA: Hhal_1054
TGR: Tgr7_0119
HNA: Hneap_0694
HCH: HCH_00037(aroE)
CSA: Csal_0293 Csal_2862
ABO: ABO_0136(aroE)
MMW: Mmwyl1_0062 Mmwyl1_0070 Mmwyl1_3919
AHA: AHA_0266(aroE)
ASA: ASA_4132(aroE)
TAU: Tola_0160 Tola_2080
DNO: DNO_0509(aroE)
AFE: Lferr_0361
AFR: AFE_0182(aroE)
BCI: BCI_0418(aroE)
RMA: Rmag_0435(aroE)
VOK: COSY_0405(aroE)
KKO: Kkor_0160
NMA: NMA2129
NME: NMB0358(aroE)
NMC: NMC1810(aroE)
NMN: NMCC_1783(aroE)
NMI: NMO_1682(aroE)
NGO: NGO1602
NGK: NGK_1905
CVI: CV_3587(aroE)
LHK: LHK_01873(aroE)
RSO: RSc2777(aroE) RSp1398(aroE)
RPI: Rpic_3021(aroE) Rpic_4302
RPF: Rpic12D_2611 Rpic12D_4412
REU: Reut_A2855(aroE) Reut_B5029
REH: H16_A3161(aroE)
RME: Rmet_3054(aroE)
CTI: RALTA_A2636(aroE)
BMA: BMA2494(aroE) BMAA0850(aroE)
BMV: BMASAVP1_1754 BMASAVP1_A0414(aroE)
BML: BMA10229_2208 BMA10229_A1274(aroE)
BMN: BMA10247_3291(aroE) BMA10247_A0893
BPS: BPSL2976(aroE) BPSS0341(aroE)
BPM: BURPS1710b_3493(aroE) BURPS1710b_A1897(aroE)
BPL: BURPS1106A_3496(aroE) BURPS1106A_A0483(aroE)
BPD: BURPS668_3458(aroE) BURPS668_A0580(aroE)
BPR: GBP346_A3640(aroE)
BTE: BTH_I1171(aroE) BTH_II2057
BVI: Bcep1808_0587(aroE) Bcep1808_3551 Bcep1808_4752
BUR: Bcep18194_A3695(aroE) Bcep18194_B0345(aroE)
BCN: Bcen_0130(aroE) Bcen_3064 Bcen_5532
BCH: Bcen2424_0613(aroE) Bcen2424_5303 Bcen2424_5896
BCM: Bcenmc03_0581(aroE) Bcenmc03_4965 Bcenmc03_6405
BCJ: BCAL3413(aroE) BCAM2501(aroE) BCAS0366
BAM: Bamb_0514(aroE) Bamb_4664 Bamb_5913 Bamb_6532
BAC: BamMC406_0538(aroE) BamMC406_4665 BamMC406_5192 BamMC406_5799
BamMC406_6247
BMU: Bmul_2772(aroE) Bmul_3420 Bmul_6127
BMJ: BMULJ_00465(aroE) BMULJ_05108(aroE) BMULJ_05404(aroE)
BXE: Bxe_A0539(aroE) Bxe_B0884 Bxe_C0879
BPH: Bphy_2622(aroE) Bphy_6024 Bphy_6097 Bphy_6410
BPY: Bphyt_3419(aroE) Bphyt_4569 Bphyt_5512 Bphyt_5792 Bphyt_6063
BGL: bglu_1g05140 bglu_2g03870 bglu_2g09580
PNU: Pnuc_0217
PNE: Pnec_0238
BPE: BP3004(aroE)
BPA: BPP3924(aroE)
BBR: BB4397(aroE)
BPT: Bpet0567(aroE)
BAV: BAV3004(aroE)
RFR: Rfer_3413(aroE)
POL: Bpro_1087(aroE) Bpro_1847 Bpro_4495 Bpro_4503
PNA: Pnap_1555 Pnap_1561 Pnap_1649 Pnap_2706 Pnap_3407(aroE)
AAV: Aave_0841(aroE)
AJS: Ajs_3656(aroE)
VEI: Veis_2197(aroE)
DAC: Daci_1482(aroE) Daci_4437
DIA: Dtpsy_2966
VAP: Vapar_0935 Vapar_3325 Vapar_3329 Vapar_5700
CTT: CtCNB1_1926 CtCNB1_4102
MPT: Mpe_A3201(aroE)
HAR: HEAR2753(aroE)
MMS: mma_2962(aroE)
LCH: Lcho_0419 Lcho_1437 Lcho_2414(aroE) Lcho_2425 Lcho_3685
NEU: NE1627(aroE1)
NET: Neut_0496
NMU: Nmul_A0538
EBA: ebA1735(aroE)
AZO: azo0707(aroE)
DAR: Daro_3907
TBD: Tbd_2504
MFA: Mfla_2445
MMB: Mmol_2136
MEI: Msip34_2490
APP: CAP2UW1_0285
HPY: HP1249(aroE)
HPJ: jhp1170(aroE)
HPA: HPAG1_1192(aroE)
HPS: HPSH_06470(aroE)
HPG: HPG27_1194(aroE)
HPP: HPP12_1215(aroE)
HPB: HELPY_1225(aroE)
HHE: HH1247(aroE)
HAC: Hac_0244(aroE)
WSU: WS2168(aroE)
TDN: Suden_1278(aroE)
CJE: Cj0405(aroE)
CJR: CJE0454(aroE)
CJJ: CJJ81176_0429(aroE)
CJU: C8J_0380(aroE)
CJD: JJD26997_1552(aroE)
CFF: CFF8240_1138(aroE)
CCV: CCV52592_1353(aroE)
CHA: CHAB381_1649(aroE)
CCO: CCC13826_0229(aroE)
CLA: Cla_0492(aroE)
ABU: Abu_1073(aroE)
SDL: Sdel_0571
NIS: NIS_1181(aroE)
SUN: SUN_0470(aroE)
NAM: NAMH_0904(aroE)
GSU: GSU1490(aroE)
GME: Gmet_1392
GUR: Gura_2683
GLO: Glov_1652
GBM: Gbem_2596
GEO: Geob_3375
GEM: GM21_1630
PCA: Pcar_2150 Pcar_2192
PPD: Ppro_2359
DVU: DVU0115(aroE)
DVL: Dvul_2848
DVM: DvMF_1962
DDE: Dde_3564
DDS: Ddes_2096
DMA: DMR_07350(aroE)
DSA: Desal_3822
DBA: Dbac_2724
DRT: Dret_0088
BBA: Bd1508(aroE)
DPS: DP3012
DOL: Dole_3109
DAL: Dalk_1761
DAT: HRM2_22490(aroE1)
ADE: Adeh_0185
ACP: A2cp1_0207
AFW: Anae109_0205
ANK: AnaeK_0196
SCL: sce1639(aroE1) sce2226(aroE2) sce2476(aroE3)
HOH: Hoch_6806
SAT: SYN_01937
SFU: Sfum_2721
PUB: SAR11_0341(aroE)
MLO: mlr4492(aroE)
MES: Meso_2294 Meso_3480(aroE) Meso_3972
PLA: Plav_1254
SME: SM_b20037(aroE) SMc02791(aroE)
SMD: Smed_3211(aroE) Smed_5698
ATU: Atu0003(aroE) Atu4295(aroE) Atu4532(aroE)
ATC: AGR_C_3 AGR_L_1139 AGR_L_673
ARA: Arad_0002(aroEch1) Arad_7777(aroEc) Arad_8808(aroEc)
AVI: Avi_0004(aroE) Avi_5454(aroE)
RET: RHE_CH00003(aroE) RHE_CH02291(aroEch2) RHE_PC00214(aroEc)
REC: RHECIAT_CH0000004(aroE)
RLE: RL0003(aroE) RL2845(aroE) RL2847 pRL110081
RLT: Rleg2_3465 Rleg2_3937(aroE) Rleg2_5945 Rleg2_6263
RLG: Rleg_4263 Rleg_7085
RHI: NGR_b00200 NGR_b06000 NGR_b22730 NGR_c33520(aroE)
BME: BMEI2058(aroE) BMEII0871
BMI: BMEA_B0036 BMEA_B0376
BMF: BAB1_2070(aroE) BAB2_0033 BAB2_0825
BMB: BruAb1_2044(aroE) BruAb2_0034 BruAb2_0804
BMC: BAbS19_I19380(aroE) BAbS19_II00320 BAbS19_II07640
BMS: BR2069(aroE)
BMT: BSUIS_A1910(aroE) BSUIS_B0036 BSUIS_B0400
BOV: BOV_1989(aroE) BOV_A0031 BOV_A0340
BCS: BCAN_A2115(aroE) BCAN_B0036 BCAN_B0400(aroE)
BMR: BMI_I2091(aroE) BMI_II34 BMI_II394
OAN: Oant_0851(aroE) Oant_4426
BJA: bll1059(aroE) bll3660 bll6391(aroE) bll6392 bll7412(aroE)
blr2257(aroE) blr3543 blr3858
BRA: BRADO0968 BRADO2346(aroE) BRADO5598(aroE) BRADO5961(aroE)
BBT: BBta_1809(aroE) BBta_6119(aroE) BBta_7088
RPA: RPA4325(aroE)
RPB: RPB_1302
RPC: RPC_4117
RPD: RPD_3919
RPE: RPE_4171
RPT: Rpal_4803
NWI: Nwi_2977
NHA: Nham_1109
OCA: OCAR_7169(aroE)
BHE: BH00030(aroE)
BQU: BQ00030(aroE)
BBK: BARBAKC583_0006(aroE)
BTR: Btr_0003(aroE)
BGR: Bgr_00030(aroE)
XAU: Xaut_1616 Xaut_1829 Xaut_2703
AZC: AZC_0003 AZC_1453
MEX: Mext_1489
MEA: Mex_1p1380
MDI: METDI2150
MRD: Mrad2831_0333 Mrad2831_4285
MET: M446_1035 M446_4753(aroE)
MPO: Mpop_1489
MCH: Mchl_1767
MNO: Mnod_0118 Mnod_0120 Mnod_1275 Mnod_3753 Mnod_5661 Mnod_8643
BID: Bind_0104 Bind_3294 Bind_3572
MSL: Msil_2537
CCR: CC_0003
CCS: CCNA_00003
CAK: Caul_0575 Caul_5013
PZU: PHZ_c0003(aroE)
SIL: SPO2425(aroE) SPO3891(aroE)
SIT: TM1040_2860(aroE)
RSP: RSP_1234(aroE)
RSH: Rsph17029_2895(aroE)
RSQ: Rsph17025_2671(aroE)
RSK: RSKD131_2632
JAN: Jann_0196(aroE)
RDE: RD1_0438(aroE)
PDE: Pden_2813(aroE) Pden_4664
DSH: Dshi_3450(aroE)
MMR: Mmar10_2976
HNE: HNE_0003(aroE)
HBA: Hbal_3146
ZMO: ZMO0041
ZMN: Za10_1136
NAR: Saro_0115 Saro_1590
SAL: Sala_2840
SWI: Swit_2830
ELI: ELI_12990
GOX: GOX0859 GOX1959
GBE: GbCGDNIH1_2144
ACR: Acry_2761
GDI: GDI_0015 GDI_2966(aroE)
GDJ: Gdia_1772 Gdia_3384
APT: APA01_08690
RRU: Rru_A3613(aroE)
RCE: RC1_2801(aroE)
MAG: amb4547(aroE)
MGM: Mmc1_0022
BSU: BSU25660(aroD)
BHA: BH1324(aroE)
BAN: BA4561(aroE)
BAR: GBAA4561(aroE)
BAA: BA_5005
BAT: BAS4232(aroE)
BAH: BAMEG_4597(aroE)
BAI: BAA_4579(aroE)
BCE: BC4331(aroE)
BCA: BCE_4415(aroE)
BCZ: BCZK4080(aroE)
BCR: BCAH187_A4467(aroE)
BCB: BCB4264_A4454(aroE)
BCU: BCAH820_4356(aroE)
BCG: BCG9842_B0783(aroE)
BCQ: BCQ_4120(aroE)
BCX: BCA_4445(aroE)
BCY: Bcer98_3060(aroE)
BTK: BT9727_4070(aroE)
BTL: BALH_3922(aroE)
BWE: BcerKBAB4_4185(aroE)
BLI: BL02079(aroE)
BLD: BLi02759(aroE)
BCL: ABC1638(aroD)
BAY: RBAM_008070 RBAM_023960(aroE)
BPU: BPUM_2300(aroE) BPUM_3656
OIH: OB1987
GKA: GK2524(aroE)
GTN: GTNG_2460(aroE)
GWC: GWCH70_2458
GYM: GYMC10_1710
GYC: GYMC61_0993
AFL: Aflv_0813(aroE)
SAU: SA1424(aroE)
SAV: SAV1596(aroE)
SAW: SAHV_1583(aroE)
SAM: MW1547(aroE)
SAR: SAR1673(aroE)
SAS: SAS1533
SAC: SACOL1652(aroE)
SAB: SAB1468c(aroE)
SAA: SAUSA300_1555(aroE)
SAX: USA300HOU_1597(aroE)
SAO: SAOUHSC_01699
SAJ: SaurJH9_1653
SAH: SaurJH1_1688
SAE: NWMN_1498(aroE)
SAD: SAAV_1587(aroE)
SEP: SE1282
SER: SERP1163(aroE)
SHA: SH1319(aroE)
SSP: SSP1162
SCA: Sca_1218(aroE)
LMO: lmo0490(aroE) lmo1490 lmo2236
LMF: LMOf2365_0520(aroE) LMOf2365_1509(aroE-2) LMOf2365_2269
LMH: LMHCC_0306 LMHCC_1080(aroE) LMHCC_2147(aroE)
LMC: Lm4b_00513 Lm4b_01500 Lm4b_02263
LIN: lin0493(aroE) lin1525 lin2338
LWE: lwe0461(aroE) lwe1503(aroE) lwe2253
LSP: Bsph_3851
ESI: Exig_0765
EAT: EAT1b_2517
MCL: MCCL_1245
BBE: BBR47_19890(aroE)
PJD: Pjdr2_4021
AAC: Aaci_2016
LLA: L0061(aroE)
LLK: LLKF_1929(aroE)
LLC: LACR_1921(aroE)
LLM: llmg_1939(aroE)
SPY: SPy_0534(aroE) SPy_1584(aroE)
SPZ: M5005_Spy_0441(aroE) M5005_Spy_1303(aroE)
SPM: spyM18_0600(aroE) spyM18_1592(aroE)
SPG: SpyM3_0378(aroE) SpyM3_1284(aroE.1)
SPS: SPs0577 SPs1475(aroE)
SPH: MGAS10270_Spy0442(aroE) MGAS10270_Spy1418(aroE)
SPI: MGAS10750_Spy0461(aroE) MGAS10750_Spy1412(aroE)
SPJ: MGAS2096_Spy0460(aroE) MGAS2096_Spy1323(aroE)
SPK: MGAS9429_Spy0440(aroE) MGAS9429_Spy1297(aroE)
SPF: SpyM50552(aroE) SpyM51423(aroE)
SPA: M6_Spy0475(aroE) M6_Spy1321
SPB: M28_Spy0429(aroE) M28_Spy1344(aroE)
SOZ: Spy49_0450(aroE) Spy49_1225c(aroE1)
SPN: SP_1376(aroE)
SPD: SPD_1210(aroE)
SPR: spr1234(aroE)
SPW: SPCG_1366(aroE)
SPX: SPG_1317(aroE)
SNE: SPN23F_13420(aroE)
SPV: SPH_1508(aroE)
SNM: SP70585_1415(aroE)
SJJ: SPJ_1276(aroE)
SPP: SPP_1396(aroE)
SNT: SPT_0897(aroE)
SAG: SAG1680(aroE)
SAN: gbs1724
SAK: SAK_1692(aroE)
SMU: SMU.778(aroE)
STC: str0639(aroE)
STL: stu0639(aroE)
STE: STER_0689(aroE)
SSA: SSA_1469(aroE)
SSU: SSU05_1251(aroE)
SSV: SSU98_1266(aroE)
SSB: SSUBM407_0701(aroE)
SSI: SSU1088(aroE)
SSS: SSUSC84_1121(aroE)
SGO: SGO_1374(aroE)
SEQ: SZO_04610
SEZ: Sez_1495(aroE)
SEU: SEQ_1681
SUB: SUB1362(aroE)
SDS: SDEG_1576(aroE)
LPL: lp_1084(aroD1) lp_3494(aroE) lp_3498(aroD3) lp_3499(aroD4)
LPJ: JDM1_0894(aroD1) JDM1_2786(aroE) JDM1_2789(aroD3)
JDM1_2790(aroD4)
LSA: LSA0892(aroE)
LSL: LSL_1795(aroE)
LCA: LSEI_0476 LSEI_0478(aroE)
LCB: LCABL_05410(aroD4) LCABL_05430(aroE)
LHE: lhv_1539
LRH: LGG_00564(aroD4) LGG_00566(aroD2)
EFA: EF1561(aroE)
LME: LEUM_1168
LCI: LCK_00697(aroE)
CAC: CAC0897(aro)
CPE: CPE0700(aroE)
CPF: CPF_0693(aroE)
CPR: CPR_0693(aroE)
CTC: CTC01117
CNO: NT01CX_0621(aroE)
CTH: Cthe_0854
CDF: CD1837(aroE) CD2708(ydiB)
CDC: CD196_1757(aroE) CD196_2549(ydiB)
CDL: CDR20291_1732(aroE) CDR20291_2596(ydiB)
CBO: CBO2540
CBA: CLB_2416(aroE)
CBH: CLC_2398(aroE)
CBY: CLM_2844(aroE)
CBL: CLK_1923(aroE)
CBK: CLL_A3139(aroE)
CBB: CLD_2096(aroE)
CBI: CLJ_B2770(aroE)
CBT: CLH_0668(aroE) CLH_2889(aroE)
CBF: CLI_2602(aroE)
CBE: Cbei_4572
CKL: CKL_0790(aroE1) CKL_1008(aroE) CKL_1014(aroE3)
CKR: CKR_0707 CKR_0912 CKR_0918
CPY: Cphy_2525
CCE: Ccel_0663
AMT: Amet_1075
AOE: Clos_0042
STH: STH1952
ATE: Athe_1889
DSY: DSY2394
DHD: Dhaf_3537
DRM: Dred_1018
DAE: Dtox_2746
PTH: PTH_1129(aroE)
DAU: Daud_0987
HMO: HM1_0245(aroE)
EEL: EUBELI_01327
ERE: EUBREC_2843 EUBREC_2850
TTE: TTE1261(aroE)
TEX: Teth514_1503
TPD: Teth39_1066
CHY: CHY_0623(aroE)
MTA: Moth_1558
ADG: Adeg_0656
CSC: Csac_1055
NTH: Nther_1732
HOR: Hore_05960
ACL: ACL_0220(aroE)
MTU: Rv2552c(aroE)
MTC: MT2629(aroE)
MRA: MRA_2581(aroE)
MTF: TBFG_12573(aroE)
MTB: TBMG_01420(TBMG_01420.1)
MBO: Mb2582c(aroE)
MBB: BCG_2575c(aroE)
MBT: JTY_2569(aroE)
MLE: ML0515(aroE)
MLB: MLBr_00515(aroE)
MPA: MAP1080(aroE)
MAV: MAV_3428(aroE)
MSM: MSMEG_3028(aroE) MSMEG_5457 MSMEG_6704
MUL: MUL_1757(aroE)
MVA: Mvan_2643(aroE) Mvan_4817
MGI: Mflv_1916 Mflv_3760(aroE)
MAB: MAB_2848c(aroE)
MMC: Mmcs_2349(aroE) Mmcs_4283
MKM: Mkms_2396(aroE) Mkms_4369
MJL: Mjls_2390(aroE) Mjls_4662
MMI: MMAR_2173(aroE)
CGL: NCgl0409(aroE) NCgl1087(aroE) NCgl1567(aroE)
CGB: cg0504(aroE) cg1283(aroE) cg1835(aroE)
CGT: cgR_0495 cgR_1216 cgR_1677(aroE)
CEF: CE0443(aroE) CE1194(aroE) CE1745(aroE)
CDI: DIP1006(aroE) DIP1347(aroE)
CJK: jk1035(aroE)
CUR: cur_0955
CAR: cauri_1390(aroE)
CKP: ckrop_1004
NFA: nfa36410(aroE)
RHA: RHA1_ro01342(aroE1) RHA1_ro01564(aroE2) RHA1_ro01853(aroE3)
RHA1_ro07138(aroE)
RER: RER_29880(aroE) RER_38080 RER_39840 RER_46930
ROP: ROP_10580(aroE) ROP_12660 ROP_15380(aroE) ROP_21990(aroE)
ROP_69190(aroE)
GBR: Gbro_2323 Gbro_2789
SCO: SCO1498(aroE)
SMA: SAV_1777(aroE) SAV_6853(aroE)
SGR: SGR_6037(aroE)
TWH: TWT373(aroE)
TWS: TW396(aroE)
LXX: Lxx00310(aroE) Lxx10940(aroE)
CMI: CMM_1799(aroE)
CMS: CMS_0732
ART: Arth_2275 Arth_2889 Arth_3498 Arth_4080
AAU: AAur_2278(aroE) AAur_2878(aroE) AAur_4046(aroE)
ACH: Achl_2012 Achl_2599 Achl_3856
RSA: RSal33209_1678 RSal33209_1976
KRH: KRH_13430(aroE)
MLU: Mlut_12690
BCV: Bcav_2017
BFA: Bfae_16330
JDE: Jden_1348
KSE: Ksed_12540
XCE: Xcel_1693
PAC: PPA1181
NCA: Noca_2410
TFU: Tfu_2067
TCU: Tcur_2138
SRO: Sros_6090
FRA: Francci3_0433 Francci3_3211
FRE: Franean1_1663 Franean1_1697 Franean1_7015 Franean1_7058
FAL: FRAAL0918 FRAAL5249(aroE)
ACE: Acel_1327
NML: Namu_2895 Namu_3294 Namu_4100 Namu_5349
KRA: Krad_3029 Krad_3445
SEN: SACE_2055(aroE) SACE_2867(rifI)
SVI: Svir_15300
AMI: Amir_5262
STP: Strop_1831
SAQ: Sare_1274 Sare_1822
CAI: Caci_2381
BLO: BL0704(aroE)
BLJ: BLD_0429(aroE)
BLN: Blon_1084
BAD: BAD_0838(aroE)
BLA: BLA_1369(aroE)
BLC: Balac_0854
BLT: Balat_0854
RXY: Rxyl_1362
AFO: Afer_0954
CCU: Ccur_12500
SHI: Shel_06560
ELE: Elen_2551
CTR: CT370(aroDE)
CTA: CTA_0402(aroDE)
CTB: CTL0624(aroDE)
CTL: CTLon_0622(aroDE)
CTJ: JALI_3681(aroE)
CMU: TC0649(aroDE)
CPN: CPn1035(aroDE)
CPA: CP0817(aroDE)
CPJ: CPj1035(aroDE)
CPT: CpB1075(aroDE)
CCA: CCA00727(aroDE)
CAB: CAB694(aroDE)
CFE: CF0289(aroDE)
PCU: pc0882(aroA)
LIL: LA0638(aroE)
LIC: LIC12949(aroE)
LBJ: LBJ_2329(aroE)
LBL: LBL_0779(aroE)
LBI: LEPBI_I0837(aroE)
LBF: LBF_0806(aroE)
BHY: BHWA1_01175(aroE)
ABA: Acid345_4110
SUS: Acid_3092 Acid_3529 Acid_7159
BTH: BT_4215
BFR: BF0916
BFS: BF0838(aroE)
BVU: BVU_2541
PGI: PG0978(aroE)
PGN: PGN_0974
PDI: BDI_1989
APS: CFPG_567
SRU: SRU_2277(aroE)
RMR: Rmar_0148
CHU: CHU_0006(aroE)
DFE: Dfer_4321
CPI: Cpin_1671
PHE: Phep_4157
GFO: GFO_0767(aroE)
FJO: Fjoh_2589
FPS: FP1769(aroE)
FBA: FIC_01652
COC: Coch_2085
RBI: RB2501_01815
SMG: SMGWSS_180(aroE)
SMS: SMDSEM_184(aroE)
BBL: BLBBGE_142
BPI: BPLAN_492(aroE)
FSU: Fisuc_2245
FNU: FN0044 FN0045
LBA: Lebu_1670
STR: Sterm_2373
SMF: Smon_0743
OTE: Oter_0500 Oter_3896
MIN: Minf_2478(aroE)
AMU: Amuc_1971
GAU: GAU_1681(aroE)
RBA: RB6488
RSD: TGRD_695
TAI: Taci_1636
SYN: slr1559(aroE)
SYW: SYNW2509(aroE)
SYC: syc1637_d(aroE)
SYF: Synpcc7942_2467(aroE)
SYD: Syncc9605_2675(aroE)
SYE: Syncc9902_2304(aroE)
SYG: sync_2924(aroE)
SYR: SynRCC307_2518(aroE)
SYX: SynWH7803_2515(aroE)
SYP: SYNPCC7002_A1730(aroE)
CYA: CYA_2729(aroE)
CYB: CYB_1006(aroE)
TEL: tll0590(aroE)
MAR: MAE_37780(aroE)
CYT: cce_4473(aroE)
CYP: PCC8801_4417(aroE)
CYC: PCC7424_0690(aroE)
CYN: Cyan7425_2736
CYH: Cyan8802_4481
GVI: gvip451(aroE)
ANA: alr2057(aroE)
NPU: Npun_R4233(aroE)
AVA: Ava_3106(aroE)
PMA: Pro1872(aroE)
PMM: PMM1705(aroE)
PMT: PMT2257(aroE)
PMN: PMN2A_1314(aroE)
PMI: PMT9312_1798(aroE)
PMB: A9601_19151(aroE)
PMC: P9515_18961(aroE)
PMF: P9303_30051(aroE)
PMG: P9301_18961(aroE)
PMH: P9215_19781(aroE)
PMJ: P9211_18411
PME: NATL1_21871(aroE)
TER: Tery_2187(aroE)
AMR: AM1_3157(aroE)
CTE: CT1809(aroE)
CPC: Cpar_1649
CCH: Cag_1345
CPH: Cpha266_0708
CPB: Cphamn1_1774
CLI: Clim_1797
PVI: Cvib_0539
PLT: Plut_0483
PPH: Ppha_2066
PAA: Paes_1654
CTS: Ctha_1609
DET: DET0465(aroE)
DEH: cbdb_A429(aroE)
DEB: DehaBAV1_0442(aroE)
DEV: DhcVS_408(aroE)
RRS: RoseRS_1564
RCA: Rcas_3415
CAU: Caur_1944
CAG: Cagg_1838
CHL: Chy400_2098
HAU: Haur_4468
TRO: trd_A0871(aroE)
DRA: DR_0077(aroE) DR_1173
DGE: Dgeo_1271 Dgeo_2374
DDR: Deide_10760(aroE) Deide_1p01400
TTH: TTC0688
TTJ: TTHA1050
AAE: aq_901(aroE)
HYA: HY04AAS1_1184
SUL: SYO3AOP1_1303
SAF: SULAZ_1462(aroE)
PMX: PERMA_1072(aroE)
TMA: TM0346
TPT: Tpet_0574
TRQ: TRQ2_0589
TNA: CTN_0325
TNP: Tnap_0981
PMO: Pmob_1201
DTH: DICTH_0912(aroE)
DTU: Dtur_1054
TYE: THEYE_A0423(aroE)
TTR: Tter_0108
MJA: MJ1084(aroE)
MFE: Mefer_1347
MVU: Metvu_0191
MMP: MMP0936(aroE)
MMQ: MmarC5_0743(aroE)
MMX: MmarC6_1719(aroE)
MMZ: MmarC7_0183(aroE)
MAE: Maeo_0450
MVN: Mevan_0253(aroE)
MAC: MA4594(aroE)
MBA: Mbar_A0923
MMA: MM_1274
MBU: Mbur_1998
MTP: Mthe_1501
MHU: Mhun_1030
MPD: MCP_0167(aroE)
MST: Msp_0647(aroE)
MSI: Msm_1179
MKA: MK0117(aroE)
AFU: AF2327(aroE)
HAL: VNG0382G(aroE)
HSL: OE1565F(aroE)
HMA: rrnAC0707(aroE)
HWA: HQ1245A(aroE)
NPH: NP0806A(aroE)
HLA: Hlac_0456
HUT: Huta_2478
HMU: Hmuk_2932
TAC: Ta0284(aroE)
TVO: TVN1317(aroE)
PTO: PTO0600(aroE)
PAB: PAB0300(aroE)
PFU: PF1693(aroE)
TKO: TK0265(aroE)
TON: TON_1136(aroE)
TGA: TGAM_1595(aroE)
RCI: RCIX1312(aroE)
APE: APE_0574.1(aroE)
IHO: Igni_0215
SSO: SSO0306(aroE)
STO: ST2273
SAI: Saci_0185(aroE)
SIS: LS215_1936
SIA: M1425_1796
SIM: M1627_1914
SID: M164_1844
SIY: YG5714_1913
SIN: YN1551_1012
MSE: Msed_1874
PAI: PAE1913
PIS: Pisl_1764
PCL: Pcal_0880
PAS: Pars_2118
CMA: Cmaq_0805
TNE: Tneu_0781
NMR: Nmar_0550
KCR: Kcr_1090
 |
|---|
| Structures |
PDB: 1NPD 1NVT 1NYT 1O9B 1P74 1P77 1VI2 1WXD 2CY0 2D5C
2EGG 2EV9 2GPT 2HK7 2HK8 2HK9 2NLO 2O7Q 2O7S 3DON
3DOO 3FBT |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:13686342]
BALINSKY D, DAVIES DD.
Aromatic biosynthesis in higher plants. 1. Preparation and
properties of dehydroshikimic reductase.
Biochem. J. 80 (1961) 292-6.
Saccharomyces cerevisiae [GN:sce], Escherichia coli [GN:eco],
Spinacia oleracea, Pisum sativum, Klebsiella pneumoniae [GN:kpn],
Euglena gracilis |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:13208693]
MITSUHASHI S, DAVIS BD.
Aromatic biosynthesis. XIII. Conversion of quinic acid to
5-dehydroquinic acid by quinic dehydrogenase.
Biochim. Biophys. Acta. 15 (1954) 268-80.
Klebsiella pneumoniae [GN:kpn] |
|---|
Reference
Authors
Title
Journal
Organism
|
3 [PMID:14367339]
YANIV H, GILVARG C.
Aromatic biosynthesis. XIV. 5-Dehydroshikimic reductase.
J. Biol. Chem. 213 (1955) 787-95.
Escherichia coli [GN:eco] |
|---|
Reference
Authors
Title
Journal
Organism
|
4 [PMID:3883995]
Chaudhuri S, Coggins JR.
The purification of shikimate dehydrogenase from Escherichia coli.
Biochem. J. 226 (1985) 217-23.
Escherichia coli [GN:eco] |
|---|
Reference
Authors
Title
Journal
Organism
|
5 [PMID:3277621]
Anton IA, Coggins JR.
Sequencing and overexpression of the Escherichia coli aroE gene
encoding shikimate dehydrogenase.
Biochem. J. 249 (1988) 319-26.
Escherichia coli [GN:eco] |
|---|
Reference
Authors
Title
Journal
Organism
|
6 [PMID:12837789]
Ye S, Von Delft F, Brooun A, Knuth MW, Swanson RV, McRee DE.
The crystal structure of shikimate dehydrogenase (AroE) reveals a
unique NADPH binding mode.
J. Bacteriol. 185 (2003) 4144-51.
Haemophilus influenzae |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 1.1.1.25
IUBMB Enzyme Nomenclature: 1.1.1.25
ExPASy - ENZYME nomenclature database: 1.1.1.25
BRENDA, the Enzyme Database: 1.1.1.25
CAS: 9026-87-3 |
|---|
