| Entry |
|
|---|
| Name |
1-deoxy-D-xylulose-5-phosphate reductoisomerase;
DXP-reductoisomerase;
1-deoxy-D-xylulose-5-phosphate isomeroreductase;
2-C-methyl-D-erythritol 4-phosphate (MEP) synthase |
|---|
| Class |
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
 |
|---|
| Sysname |
2-C-methyl-D-erythritol-4-phosphate:NADP+ oxidoreductase
(isomerizing) |
|---|
| Reaction(IUBMB) |
2-C-methyl-D-erythritol 4-phosphate + NADP+ = 1-deoxy-D-xylulose
5-phosphate + NADPH + H+ [RN:R05688] |
|---|
| Reaction(KEGG) |
R05688
 |
|---|
| Substrate |
2-C-methyl-D-erythritol 4-phosphate [CPD:C11434];
NADP+ [CPD:C00006] |
|---|
| Product |
1-deoxy-D-xylulose 5-phosphate [CPD:C11437];
NADPH [CPD:C00005];
H+ [CPD:C00080] |
|---|
| Comment |
The enzyme requires Mn2+, Co2+ or Mg2+ for activity, with the first
being most effective. The enzyme from several eubacteria, including
Escherichia coli, forms part of an alternative nonmevalonate pathway
for terpenoid biosynthesis (for diagram, click here). The mechanism
has been shown to be a retroaldol/aldol reaction [2]. |
|---|
| Pathway |
PATH: ec00900 Terpenoid backbone biosynthesis
PATH: ec01062 Biosynthesis of terpenoids and steroids
PATH: ec01066 Biosynthesis of alkaloids derived from terpenoid and
polyketide
PATH: ec01070 Biosynthesis of plant hormones
PATH: ec01100 Metabolic pathways |
|---|
| Orthology |
KO: K00099 1-deoxy-D-xylulose-5-phosphate reductoisomerase |
|---|
| Genes |
ATH: AT5G62790(DXR)
POP: POPTR_728585 POPTR_733324
RCU: RCOM_1510580
VVI: 100248516(GSVIVT00016085001)
OSA: 4326153(Os01g0106900)
ZMA: 542023(IDP154)
PPP: PHYPADRAFT_127023 PHYPADRAFT_128953
CRE: CHLREDRAFT_196606(DXR1)
OLU: OSTLU_31255(DXR)
CME: CMG148C
PFA: PF14_0641
PFD: PFDG_00980
PYO: PY05578
PCB: PC000189.01.0 PC301429.00.0
PBE: PB000946.02.0
PKN: PKH_123820
TAN: TA14290
TPV: TP02_0073
BBO: BBOV_III010740
TGO: TGME49_014850
PTI: PHATRDRAFT_43204(DXR)
TPS: THAPS_10943(DXR1)
ECO: b0173(dxr)
ECJ: JW0168(dxr)
ECD: ECDH10B_0153(dxr)
EBW: BWG_0165(dxr)
ECE: Z0184(yaeM)
ECS: ECs0175
ECF: ECH74115_0183(dxr)
ETW: ECSP_0172(dxr)
ECG: E2348C_0178(dxr)
ECI: UTI89_C0188(dxr)
ECP: ECP_0181
ECV: APECO1_1814(dxr)
ECW: EcE24377A_0177(dxr)
ECX: EcHS_A0175(dxr)
ECM: EcSMS35_0184(dxr)
ECY: ECSE_0172
ECL: EcolC_3487
ECK: EC55989_0167(dxr)
ECQ: ECED1_0179(dxr)
ECR: ECIAI1_0171(dxr)
ECT: ECIAI39_0176(dxr)
ECZ: ECS88_0183(dxr)
EUM: ECUMN_0170(dxr)
ELF: LF82_0535(dxr)
EBL: B21_00170(ispC)
EBD: ECBD_3446
EBR: ECB_00171(ispC)
EOH: ECO103_0171(dxr)
EOI: ECO111_0174(dxr)
EOJ: ECO26_0175(dxr)
EFE: EFER_0195(dxr)
STY: STY0243(dxr)
STT: t0221(dxr)
SPT: SPA0227(dxr)
SEK: SSPA0219
SPQ: SPAB_00282
SEI: SPC_0236(dxr)
SEC: SC0220(dxr)
SEH: SeHA_C0258(dxr)
SEE: SNSL254_A0242(dxr)
SEW: SeSA_A0245(dxr)
SEA: SeAg_B0260(dxr)
SED: SeD_A0242(dxr)
SEG: SG0224(dxr)
SET: SEN0227(dxr)
SES: SARI_02782
STM: STM0220(dxr)
YPE: YPO1048(dxr)
YPK: y3131
YPM: YP_2802(dxr)
YPA: YPA_0524
YPN: YPN_2952
YPG: YpAngola_A3431(dxr)
YPP: YPDSF_1664
YPS: YPTB2999(dxr)
YPI: YpsIP31758_1017(dxr)
YPY: YPK_1070
YPB: YPTS_3119
YEN: YE3280(b0173)
SFL: SF0163(yaeM)
SFX: S0166(yaeM)
SFV: SFV_0156(yaeM)
SSN: SSON_0185(yaeM)
SBO: SBO_0161(yaeM)
SBC: SbBS512_E0166(dxr)
SDY: SDY_0189(yaeM)
ECA: ECA1035(dxr)
PCT: PC1_0945
PWA: Pecwa_3356
ETA: ETA_08940(dxr)
PLU: plu0676(dxr)
PAY: PAU_00648(dxr)
BUC: BU235(dxr)
BAS: BUsg229(dxr)
BAP: BUAP5A_230(dxr)
BAU: BUAPTUC7_232(dxr)
WBR: WGLp388(yaeM)
SGL: SG1939
ENT: Ent638_0711
ESA: ESA_03169
CTU: Ctu_08010(dxr)
KPN: KPN_00186(ispC)
KPE: KPK_4547(dxr)
KPU: KP1_1027(ispC)
CKO: CKO_03194
SPE: Spro_3786
PMR: PMI2281(dxr)
EIC: NT01EI_0842
ETR: ETAE_0741(dxr)
BFL: Bfl275(dxr)
BPN: BPEN_283(dxr)
HDE: HDEF_1308(dxr)
DDA: Dd703_2977
DDC: Dd586_0933
DZE: Dd1591_3161
HIN: HI0807
HIT: NTHI0971(dxr)
HIP: CGSHiEE_08025
HIQ: CGSHiGG_07530
HDU: HD1186(dxr)
HAP: HAPS_0729(dxr)
HSO: HS_0985(dxr)
HSM: HSM_1463
PMU: PM1988(dxr)
MSU: MS1928(dxr)
APL: APL_0406(dxr)
APJ: APJL_0428(dxr)
APA: APP7_0430
ASU: Asuc_0657
AAP: NT05HA_1558
AAT: D11S_0244
XFA: XF1048
XFT: PD0328(dxr)
XFM: Xfasm12_0359
XFN: XfasM23_0324
XCC: XCC1367(dxr)
XCB: XC_2871
XCA: xccb100_2929(dxr)
XCV: XCV1472(dxr)
XAC: XAC1415(dxr)
XOO: XOO1970(dxr)
XOM: XOO_1860
XOP: PXO_01125(dxr)
SML: Smlt1500(dxr)
SMT: Smal_1259
VCH: VC2254
VCO: VC0395_A1845(dxr)
VCM: VCM66_2177(dxr)
VCJ: VCD_002087
VVU: VV1_1866
VVY: VV2551
VPA: VP2312
VHA: VIBHAR_03231
VSP: VS_2346
VEX: VEA_002752
VFI: VF_1956(dxr)
VFM: VFMJ11_2090(dxr)
VSA: VSAL_I2421(dxr)
PPR: PBPRA2962
PAE: PA3650(dxr)
PAU: PA14_17130(dxr)
PAP: PSPA7_1489(dxr)
PAG: PLES_13851(dxr)
PPU: PP_1597(dxr)
PPF: Pput_4180
PPG: PputGB1_1152
PPW: PputW619_4076
PST: PSPTO_1540(dxr)
PSB: Psyr_1349
PSP: PSPPH_3834(dxr)
PFL: PFL_1182(dxr)
PFO: Pfl01_1107
PFS: PFLU1276(dxr)
PEN: PSEEN4214(dxr)
PMY: Pmen_3047
PSA: PST_1543(dxr)
CJA: CJA_1118(dxr)
AVN: Avin_38930(dxr)
PAR: Psyc_1531(dxr)
PCR: Pcryo_1710
PRW: PsycPRwf_1798
ACI: ACIAD1376(dxr)
ACB: A1S_1971
ABM: ABSDF1684(dxr)
ABY: ABAYE1581(dxr)
ABC: ACICU_02094
ABN: AB57_2316(dxr)
ABB: ABBFA_001475(dxr)
SON: SO_1635(dxr)
SDN: Sden_1560
SFR: Sfri_1276
SAZ: Sama_1145
SBL: Sbal_1456
SBM: Shew185_1451
SBN: Sbal195_1487
SBP: Sbal223_2896
SLO: Shew_2629
SPC: Sputcn32_1354
SSE: Ssed_3155
SPL: Spea_2879
SHE: Shewmr4_2635
SHM: Shewmr7_2702
SHN: Shewana3_2809
SHW: Sputw3181_2749
SHL: Shal_2975
SWD: Swoo_3275
SWP: swp_3515
ILO: IL0839
CPS: CPS_1559(dxr)
PHA: PSHAa2030(dxr)
PAT: Patl_1255
SDE: Sde_2591
MAQ: Maqu_2542
AMC: MADE_01379
PIN: Ping_2970
MCA: MCA0573(dxr)
FTU: FTT_1574c(dxr)
FTF: FTF1574c(dxr)
FTW: FTW_0352(dxr)
FTL: FTL_0534
FTH: FTH_0536(dxr)
FTA: FTA_0567(dxr)
FTM: FTM_0324(dxr)
FTN: FTN_1483(dxr)
FPH: Fphi_1195
NOC: Noc_0814
AEH: Mlg_1857
HHA: Hhal_1460
TGR: Tgr7_1165
HNA: Hneap_1448
HCH: HCH_05246(dxr)
CSA: Csal_0569
ABO: ABO_1149(dxr)
MMW: Mmwyl1_1278
AHA: AHA_1179(dxr)
ASA: ASA_3154(dxr)
TAU: Tola_2105
AFE: Lferr_1166
AFR: AFE_1450(dxr)
BCI: BCI_0531(dxr)
RMA: Rmag_0025
VOK: COSY_0025(dxr)
KKO: Kkor_1906
NMA: NMA0083(dxr)
NME: NMB0184(dxr)
NMC: NMC0175(dxr)
NMN: NMCC_1968(dxr)
NMI: NMO_1854(dxr)
NGO: NGO1799
NGK: NGK_2475
CVI: CV_2202(dxr)
LHK: LHK_02068(dxr)
RSO: RSc1410(dxr)
RPI: Rpic_1284
RPF: Rpic12D_1348
REU: Reut_A1875
REH: H16_A2049(dxp)
RME: Rmet_1441
CTI: RALTA_A1685(dxr)
BMA: BMA1549(dxr)
BMV: BMASAVP1_A2050(dxr)
BML: BMA10229_A3261(dxr)
BMN: BMA10247_1322(dxr)
BPS: BPSL2153(dxr)
BPM: BURPS1710b_2577(dxr)
BPL: BURPS1106A_2487(dxr)
BPD: BURPS668_2431(dxr)
BPR: GBP346_A2556(dxr)
BTE: BTH_I2033(dxr)
BVI: Bcep1808_1919
BUR: Bcep18194_A5323
BCN: Bcen_6064
BCH: Bcen2424_2013
BCM: Bcenmc03_2033
BCJ: BCAL2085(dxr)
BAM: Bamb_2046
BAC: BamMC406_1915
BMU: Bmul_1263
BMJ: BMULJ_01984(dxr)
BXE: Bxe_A1688
BPH: Bphy_1332
BPY: Bphyt_2449
BGL: bglu_1g12780
PNU: Pnuc_1445
PNE: Pnec_0513
BPE: BP1425(dxr)
BPA: BPP1533(dxr)
BBR: BB2611(dxr)
BPT: Bpet2529(dxr)
BAV: BAV1740(dxr)
RFR: Rfer_1994
POL: Bpro_2689
PNA: Pnap_1764
AAV: Aave_1829
AJS: Ajs_2579
VEI: Veis_1444
DAC: Daci_4942
DIA: Dtpsy_1229
VAP: Vapar_2605
CTT: CtCNB1_3226
MPT: Mpe_A1973
HAR: HEAR1341(dxr)
MMS: mma_2052(dxr)
LCH: Lcho_2844
NEU: NE1712(dxr)
NET: Neut_2029
NMU: Nmul_A0663
EBA: ebA5994(dxr)
AZO: azo1903(dxr)
DAR: Daro_1748
TMZ: Tmz1t_2172
TBD: Tbd_0791
MFA: Mfla_1524
MMB: Mmol_1162
MEI: Msip34_1405
APP: CAP2UW1_2870
HPY: HP0216
HPJ: jhp0202
HPA: HPAG1_0217
HPS: HPSH_01115
HPG: HPG27_198
HPP: HPP12_0217
HPB: HELPY_0219(dxr)
HHE: HH0524(dxr)
HAC: Hac_1502(dxr_fragment_2) Hac_1503(dxr_fragment_1)
WSU: WS0812
TDN: Suden_0126
CJE: Cj1346c(dxr)
CJR: CJE1535(dxr)
CJJ: CJJ81176_1345(dxr)
CJU: C8J_1262(dxr)
CJD: JJD26997_0364(dxr)
CFF: CFF8240_0210(dxr)
CCV: CCV52592_0594(dxr)
CHA: CHAB381_0121(dxr)
CCO: CCC13826_0420(dxr)
CLA: Cla_1535(dxr)
ABU: Abu_0161(dxr)
SDL: Sdel_2249
NIS: NIS_1666(ispC)
SUN: SUN_0144
NAM: NAMH_0236(dxr)
GSU: GSU1915(dxr)
GME: Gmet_1256
GUR: Gura_3727
GLO: Glov_2714
GBM: Gbem_2750
GEO: Geob_1516
GEM: GM21_1491
PCA: Pcar_1915(dxr)
PPD: Ppro_2050
DVU: DVU0866(dxr)
DVL: Dvul_2116
DVM: DvMF_2915
DDE: Dde_1123
DDS: Ddes_0516
DMA: DMR_03860(dxr)
DSA: Desal_1253
LIP: LI0386(dxr)
DBA: Dbac_2382
DRT: Dret_1947
DPS: DP1160
DOL: Dole_0480
DAL: Dalk_3159
DAT: HRM2_17160(dxr)
ADE: Adeh_3583
ACP: A2cp1_3723
AFW: Anae109_3704
ANK: AnaeK_3649
SAT: SYN_00916
SFU: Sfum_1784
WOL: WD0992(dxr)
WBM: Wbm0179
WRI: WRi_009400(dxr)
WPI: WPa_0113(dxr)
AMA: AM743(dxr)
AMF: AMF_548(dxr)
ACN: ACIS_00584(dxr)
APH: APH_0440(dxr)
ERU: Erum4750(dxr)
ERW: ERWE_CDS_04970(dxr)
ERG: ERGA_CDS_04870(dxr)
ECN: Ecaj_0473
ECH: ECH_0557(dxr)
NSE: NSE_0443(dxr)
NRI: NRI_0419(dxr)
PUB: SAR11_0912(yaeM)
PLA: Plav_3190
SME: SMc03105(dxr)
SMD: Smed_2879
ATU: Atu2612(dxr)
ATC: AGR_C_4736
ARA: Arad_4263(dxr)
AVI: Avi_4083(dxr)
RET: RHE_CH03839(dxr)
REC: RHECIAT_CH0004120(dxr)
RLE: RL4372(dxr)
RLT: Rleg2_3617
RLG: Rleg_3905
RHI: NGR_c30680
BJA: bll4855(dxr)
BRA: BRADO4134(dxr)
BBT: BBta_4511(dxr)
RPA: RPA2916(dxr)
RPB: RPB_2822
RPC: RPC_2442
RPD: RPD_2851
RPE: RPE_2559
RPT: Rpal_3262
NWI: Nwi_1853
NHA: Nham_1700
OCA: OCAR_5961(dxr)
XAU: Xaut_4433
AZC: AZC_1699
MEX: Mext_2083
MEA: Mex_1p2068(dxr)
MDI: METDI2849(dxr)
MRD: Mrad2831_3444
MET: M446_0636
MPO: Mpop_2043
MCH: Mchl_2357
MNO: Mnod_1533
BID: Bind_0297
MSL: Msil_3835
CCR: CC_1917
CCS: CCNA_01994
CAK: Caul_2799
PZU: PHZ_c1774(dxr)
SIL: SPO1667(dxr)
SIT: TM1040_1410
RSP: RSP_2709(dxr)
RSH: Rsph17029_1366
RSQ: Rsph17025_2149
RSK: RSKD131_1025
JAN: Jann_2455
RDE: RD1_2590(dxr)
PDE: Pden_3997
DSH: Dshi_1497(dxr)
MMR: Mmar10_1386
HNE: HNE_1774(dxr)
HBA: Hbal_1711
ZMO: ZMO1150
ZMN: Za10_0176
NAR: Saro_1375
SAL: Sala_1954
SWI: Swit_0466
ELI: ELI_03805
GOX: GOX1816
GBE: GbCGDNIH1_0938
ACR: Acry_2557
GDI: GDI_2147(dxr)
GDJ: Gdia_0367
APT: APA01_06540
RRU: Rru_A1592
RCE: RC1_1202(dxr)
MAG: amb2492
MGM: Mmc1_1846
BSU: BSU16550(dxr)
BHA: BH2421
BAN: BA3409(dxr-1) BA3959(dxr-2)
BAR: GBAA3409(dxr-1) GBAA3959(dxr-2)
BAA: BA_4429
BAT: BAS3160 BAS3672
BAH: BAMEG_0673(dxr2) BAMEG_1219(dxr1)
BAI: BAA_3442(dxr1) BAA_3982(dxr2)
BCE: BC3341 BC3819
BCA: BCE_3862(dxr)
BCZ: BCZK3054(dxr) BCZK3580(dxr)
BCR: BCAH187_A3868(dxr2)
BCB: BCB4264_A3354(dxr1) BCB4264_A3919(dxr2)
BCU: BCAH820_3379(dxr1) BCAH820_3833(dxr2)
BCG: BCG9842_B1325(dxr2) BCG9842_B1872(dxr1)
BCQ: BCQ_3606(dxr)
BCX: BCA_3920(dxr2)
BCY: Bcer98_2128 Bcer98_2473
BTK: BT9727_3144(dxr) BT9727_3562(dxr)
BTL: BALH_3451
BWE: BcerKBAB4_3082 BcerKBAB4_3644
BLI: BL01237(dxr)
BLD: BLi01876(dxr)
BCL: ABC2236(dxr)
BAY: RBAM_016390(dxr)
BPU: BPUM_1554(dxr)
GKA: GK1255
GTN: GTNG_1109
GWC: GWCH70_1147
GYM: GYMC10_4151
GYC: GYMC61_2039
AFL: Aflv_1703(dxr)
LMO: lmo1317
LMF: LMOf2365_1334(dxr)
LMH: LMHCC_1253(dxr)
LMC: Lm4b_01325
LIN: lin1354
LWE: lwe1332(dxr)
LSP: Bsph_1590
ESI: Exig_1845
EAT: EAT1b_2948
MCL: MCCL_0846
BBE: BBR47_34420(dxr)
PJD: Pjdr2_3415
AAC: Aaci_1425
CAC: CAC1795
CPE: CPE1694
CPF: CPF_1948(dxr)
CPR: CPR_1666(dxr)
CTC: CTC01268
CNO: NT01CX_2143
CTH: Cthe_0999
CDF: CD2130(dxr)
CDC: CD196_1994(dxr)
CDL: CDR20291_2037(dxr)
CBO: CBO2426
CBA: CLB_2290(dxr)
CBH: CLC_2273(dxr)
CBY: CLM_2719(dxr)
CBL: CLK_1802(dxr)
CBK: CLL_A1265(dxr)
CBB: CLD_2214(dxr)
CBI: CLJ_B2651(dxr)
CBT: CLH_1216(dxr)
CBF: CLI_2482(dxr)
CBE: Cbei_1195
CKL: CKL_1423(dxr)
CKR: CKR_1318
CPY: Cphy_2622
CCE: Ccel_0449
AMT: Amet_2682
AOE: Clos_1519
STH: STH1499(dxr)
SWO: Swol_0889
VPR: Vpar_0863
ATE: Athe_1810
DSY: DSY2539
DHD: Dhaf_3702
DRM: Dred_1970
DAE: Dtox_3204
PTH: PTH_1260(dxr)
DAU: Daud_0615
HMO: HM1_2264(dxr)
EEL: EUBELI_00852
ERE: EUBREC_1767
TTE: TTE1402(dxr)
TEX: Teth514_1654
TPD: Teth39_1218
CHY: CHY_1778(dxr)
MTA: Moth_1041
ADG: Adeg_0586
CSC: Csac_2353
CPO: COPRO5265_0743
NTH: Nther_1435
HOR: Hore_07730
MPE: MYPE1470
MGA: MGA_0787(dxr)
MTU: Rv2870c(dxr)
MTC: MT2938(dxr)
MRA: MRA_2895(dxr)
MTF: TBFG_12886
MTB: TBMG_01099(TBMG_01099.1)
MBO: Mb2895c(dxr)
MBB: BCG_2892c(dxr)
MBT: JTY_2887(dxr)
MLE: ML1583
MLB: MLBr_01583
MPA: MAP2940c
MAV: MAV_3727(dxr)
MSM: MSMEG_2578(dxr)
MUL: MUL_2085(dxr)
MVA: Mvan_2260
MGI: Mflv_4083
MAB: MAB_3171c
MMC: Mmcs_2042
MKM: Mkms_2088
MJL: Mjls_2025
MMI: MMAR_1836(dxr)
CGL: NCgl1940(cgl2016)
CGB: cg2208(dxr)
CGT: cgR_1844
CEF: CE1905
CDI: DIP1500(dxr)
CJK: jk1167(ispC)
CUR: cur_0831
CAR: cauri_1552(dxr)
NFA: nfa41200(dxr)
RHA: RHA1_ro06588(dxr)
RER: RER_25520(dxr)
ROP: ROP_66220
GBR: Gbro_2117
SCO: SCO5694(dxr)
SMA: SAV_2563(dxr)
SGR: SGR_1823
TWH: TWT089(dxr)
TWS: TW099(dxr)
LXX: Lxx12180(dxr)
CMI: CMM_2160(dxrA)
CMS: CMS_1853(dxr)
ART: Arth_1399
AAU: AAur_1543(dxr)
ACH: Achl_1411
RSA: RSal33209_0635
KRH: KRH_16160(dxr)
MLU: Mlut_06920
BCV: Bcav_2500
BFA: Bfae_10200
JDE: Jden_1011
KSE: Ksed_11300
XCE: Xcel_1200
PAC: PPA1510
NCA: Noca_3204
TFU: Tfu_0747
TCU: Tcur_3372
SRO: Sros_1964
FRA: Francci3_3575
FRE: Franean1_1168
FAL: FRAAL5774(dxr)
ACE: Acel_1524
NML: Namu_2183
KRA: Krad_1427
SEN: SACE_5994(dxr)
SVI: Svir_09980
AMI: Amir_5890
STP: Strop_1350
SAQ: Sare_1302
CAI: Caci_7762
BLO: BL0097(ispC)
BLJ: BLD_0115(dxr)
BLN: Blon_0779
BAD: BAD_1158(ispC)
BLA: BLA_0828(dxr)
BLC: Balac_1250
BLT: Balat_1250
RXY: Rxyl_1404
AFO: Afer_0631
CCU: Ccur_10890
SHI: Shel_23580
APV: Apar_0711
ELE: Elen_2469
CTR: CT071(yaeM)
CTA: CTA_0076(dxr)
CTB: CTL0327(dxr)
CTL: CTLon_0322(dxr)
CTJ: JALI_0701(dxr)
CMU: TC0343(dxr)
CPN: CPn0345(yaeM)
CPA: CP0415
CPJ: CPj0344(yaeM)
CPT: CpB0352
CCA: CCA00441(dxr)
CAB: CAB427(dxr)
CFE: CF0566(yaeM)
PCU: pc0260(dxr)
TPA: TP0601
TPP: TPASS_0601(dxr)
TDE: TDE2342(dxr)
LIL: LA3292(dxr)
LIC: LIC10856(dxr)
LBJ: LBJ_0910(dxr)
LBL: LBL_0925(dxr)
LBI: LEPBI_I2611(dxr)
LBF: LBF_2531(dxr)
BHY: BHWA1_00476(dxr)
ABA: Acid345_1419
ACA: ACP_1612(dxr)
SUS: Acid_7136
BTH: BT_2002
BFR: BF3699
BFS: BF3492
BVU: BVU_1651
PGI: PG1364(dxr)
PGN: PGN_1151
PDI: BDI_0480
APS: CFPG_371
SRU: SRU_1849(dxr)
RMR: Rmar_1962
CHU: CHU_2996(dxr)
DFE: Dfer_3834
CPI: Cpin_2049
PHE: Phep_3177
FSU: Fisuc_1857
FNU: FN1324
STR: Sterm_0050
OTE: Oter_4632
MIN: Minf_1972(dxr)
AMU: Amuc_1737
GAU: GAU_1770(dxr)
RBA: RB5568(dxr)
EMI: Emin_0690
RSD: TGRD_409
TAI: Taci_0933
SYN: sll0019
SYW: SYNW0698(dxr)
SYC: syc2498_d(dxr)
SYF: Synpcc7942_1513
SYD: Syncc9605_1970
SYE: Syncc9902_0689
SYG: sync_0920(dxr)
SYR: SynRCC307_1674(dxr)
SYX: SynWH7803_1622(dxr)
SYP: SYNPCC7002_A0818(dxr)
CYA: CYA_0193(dxr)
CYB: CYB_1233(dxr)
TEL: tlr1040
MAR: MAE_50310
CYT: cce_2124(dxr)
CYP: PCC8801_2698
CYC: PCC7424_0289
CYN: Cyan7425_3999
CYH: Cyan8802_3405
GVI: gll2252
ANA: alr4351
NPU: Npun_R5970
AVA: Ava_1300
PMA: Pro1236(dxr)
PMM: PMM1142(dxr)
PMT: PMT1161(dxr)
PMN: PMN2A_0751
PMI: PMT9312_1238
PMB: A9601_13171(dxr)
PMC: P9515_13061(dxr)
PMF: P9303_08651(dxr)
PMG: P9301_13311(dxr)
PMH: P9215_13461(dxr)
PMJ: P9211_12161
PME: NATL1_15911(dxr)
TER: Tery_0416
AMR: AM1_0563(dxr)
CTE: CT0125(dxr)
CPC: Cpar_0071
CCH: Cag_0008
CPH: Cpha266_2680
CPB: Cphamn1_0098
CLI: Clim_0085
PVI: Cvib_0138
PLT: Plut_0077
PPH: Ppha_0080
PAA: Paes_0121
CTS: Ctha_1044
DET: DET0371(dxr)
DEH: cbdb_A314(dxr)
DEB: DehaBAV1_0353
DEV: DhcVS_315(dxr)
TRO: trd_1005(dxr)
STI: Sthe_1740
DRA: DR_1508
DGE: Dgeo_1044
DDR: Deide_13230(dxr)
TTH: TTC0504
TTJ: TTHA0856
AAE: aq_404
HYA: HY04AAS1_0095
SUL: SYO3AOP1_0479
SAF: SULAZ_0176(dxr)
PMX: PERMA_0141(dxr)
TMA: TM0889
TPT: Tpet_0038
TLE: Tlet_0658
TRQ: TRQ2_0038
TNA: CTN_1687
TNP: Tnap_0038
TME: Tmel_0037
TAF: THA_253
FNO: Fnod_0950
PMO: Pmob_1939
KOL: Kole_0909
DTH: DICTH_1071(dxr)
DTU: Dtur_1197
TYE: THEYE_A0226(dxr)
TTR: Tter_1704
 |
|---|
| Structures |
PDB: 1JVS 1ONN 1ONO 1ONP 1Q0H 1Q0L 1Q0Q 1R0K 1R0L 1T1R
1T1S 2C82 2EGH 2JCV 2JCX 2JCY 2JCZ 2JD0 2JD1 2JD2
3IIE |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:9707569]
Takahashi S, Kuzuyama T, Watanabe H, Seto H.
A 1-deoxy-D-xylulose 5-phosphate reductoisomerase catalyzing the
formation of 2-C-methyl-D-erythritol 4-phosphate in an alternative
nonmevalonate pathway for terpenoid biosynthesis.
Proc. Natl. Acad. Sci. U. S. A. 95 (1998) 9879-84.
Esherichia coli [GN:eco] |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:19159292]
Munos JW, Pu X, Mansoorabadi SO, Kim HJ, Liu HW
A secondary kinetic isotope effect study of the
1-deoxy-D-xylulose-5-phosphate reductoisomerase-catalyzed reaction:
evidence for a retroaldol-aldol rearrangement.
J. Am. Chem. Soc. 131 (2009) 2048-9.
Plasmodium falciparum, Mycobacterium tuberculosis |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 1.1.1.267
IUBMB Enzyme Nomenclature: 1.1.1.267
ExPASy - ENZYME nomenclature database: 1.1.1.267
BRENDA, the Enzyme Database: 1.1.1.267
CAS: 210756-42-6 |
|---|
