| Entry |
|
|---|
| Name |
homoserine dehydrogenase;
HSDH;
HSD |
|---|
| Class |
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
 |
|---|
| Sysname |
L-homoserine:NAD(P)+ oxidoreductase |
|---|
| Reaction(IUBMB) |
L-homoserine + NAD(P)+ = L-aspartate 4-semialdehyde + NAD(P)H + H+
[RN:R01773 R01775] |
|---|
| Reaction(KEGG) |
R01773 R01775
 |
|---|
| Substrate |
L-homoserine [CPD:C00263];
NAD+ [CPD:C00003];
NADP+ [CPD:C00006] |
|---|
| Product |
L-aspartate 4-semialdehyde [CPD:C00441];
NADH [CPD:C00004];
NADPH [CPD:C00005];
H+ [CPD:C00080] |
|---|
| Comment |
The yeast enzyme acts most rapidly with NAD+; the Neurospora enzyme
with NADP+. The enzyme from Escherichia coli is a multi-functional
protein, which also catalyses the reaction of EC 2.7.2.4 (aspartate
kinase). |
|---|
| Pathway |
PATH: ec00260 Glycine, serine and threonine metabolism
PATH: ec00270 Cysteine and methionine metabolism
PATH: ec00300 Lysine biosynthesis
PATH: ec01070 Biosynthesis of plant hormones
PATH: ec01100 Metabolic pathways |
|---|
| Orthology |
KO: K00003 homoserine dehydrogenase
KO: K12524 bifunctional aspartokinase/homoserine dehydrogenase 1
KO: K12525 bifunctional aspartokinase/homoserine dehydrogenase 2 |
|---|
| Genes |
NVE: NEMVE_v1g225948
ATH: AT1G31230 AT4G19710(AK-HSDH_II)
POP: POPTR_288174 POPTR_780515
RCU: RCOM_0742100
VVI: 100258602
OSA: 4345328(Os08g0342400) 4346642(Os09g0294000)
SBI: SORBI_02g019450(SORBIDRAFT_02g019450)
ZMA: 542249 542708(akh2)
PPP: PHYPADRAFT_131376 PHYPADRAFT_142581
CRE: CHLREDRAFT_196925(AHD1)
OLU: OSTLU_16870
CME: CMN129C
SCE: YJR139C(HOM6)
AGO: AGOS_ABL080W
KLA: KLLA0B03872g
LTH: KLTH0D17446g
DHA: DEHA0F01507g
PIC: PICST_57619(HOM6)
PPA: PAS_chr1-4_0049
VPO: Kpol_1024p2
LEL: LELG_01600
ZRO: ZYRO0B08756g
CAL: CaO19.10468(HOM6)
CTP: CTRG_04629
CDU: CD36_02440
CGR: CAGL0M00330g
YLI: YALI0D01089g
SPO: SPBC776.03
NCR: NCU03935
PAN: PODANSg3030
MGR: MGG_11450
FGR: FG09284.1
ANI: AN2882.2
AFM: AFUA_3G11640
AOR: AO090003000721 AO090009000136
ANG: An02g07430
AFV: AFLA_030970 AFLA_053200
PCS: Pc13g08990
NFI: NFIA_065670
CIM: CIMG_03660
URE: UREG_07422
SSL: SS1G_14424
BFU: BC1G_09640
CNE: CNJ02040
CNB: CNBJ1420
LBC: LACBIDRAFT_238324
MPR: MPER_05297
UMA: UM01708.1
MGL: MGL_2414
LMA: LmjF07.0260
LIF: LinJ07.0240
LBZ: LbrM07_V2.0270
PTI: PHATRDRAFT_22113
TPS: THAPS_29008
ECO: b0002(thrA) b3940(metL)
ECJ: JW0001(thrA) JW3911(metL)
ECD: ECDH10B_0002(thrA) ECDH10B_4129(metL)
EBW: BWG_0002(thrA) BWG_3609(metL)
ECE: Z0002(thrA) Z5495(metL)
ECS: ECs0002(thrA) ECs4869(metL)
ECF: ECH74115_0003(thrA) ECH74115_5400(metL)
ETW: ECSP_0002 ECSP_5010(metL)
ECG: E2348C_0002(thrA) E2348C_4244(metL)
ECC: c0003(thrA) c4893(metL)
ECI: UTI89_C0002(thrA) UTI89_C4525(metL)
ECP: ECP_0002(thrA) ECP_4149
ECV: APECO1_1976(thrA) APECO1_2531(metL)
ECW: EcE24377A_0001(thrA) EcE24377A_4480(metL)
ECX: EcHS_A0003(thrA) EcHS_A4174(metL)
ECM: EcSMS35_0001(thrA) EcSMS35_4382(metL)
ECY: ECSE_0002(thrA) ECSE_4234(metL)
ECL: EcolC_3653(thrA) EcolC_4075(metL)
ECK: EC55989_0002(thrA) EC55989_4422(metL)
ECQ: ECED1_0001(thrA) ECED1_4643(metL)
ECR: ECIAI1_0002(thrA) ECIAI1_4149(metL)
ECT: ECIAI39_0001(thrA) ECIAI39_3054(metL)
ECZ: ECS88_0002(thrA) ECS88_4391(metL)
EUM: ECUMN_0002(thrA) ECUMN_4470(metL)
ELF: LF82_1327(metL) LF82_2259(thrA)
EBL: B21_00002(thrA) B21_03775(metL)
EBD: ECBD_3616 ECBD_4083
EBR: ECB_00002(thrA) ECB_03826(metL)
EOH: ECO103_0002(thrA) ECO103_4697(metL)
EOI: ECO111_0002(thrA) ECO111_4766(metL)
EOJ: ECO26_0002(thrA) ECO26_4644(metL)
EFE: EFER_0001(thrA) EFER_3831(metL)
STY: STY0002(thrA) STY3768(metL)
STT: t0002(thrA) t3517(metL)
SPT: SPA0002(thrA) SPA3944(metL)
SEK: SSPA0002(thrA) SSPA3671(metL)
SPQ: SPAB_00002(thrA) SPAB_05082(metL)
SEI: SPC_0002(thrA) SPC_4210(metL)
SEC: SC0002(thrA) SC3992(metL)
SEH: SeHA_C0002(thrA) SeHA_C4435(metL)
SEE: SNSL254_A0002(thrA) SNSL254_A4432(metL)
SEW: SeSA_A0002(thrA) SeSA_A4318(metL)
SEA: SeAg_B0002(thrA) SeAg_B4348(metL)
SED: SeD_A0002(thrA) SeD_A4502(metL)
SEG: SG0002(thrA) SG3319(metL)
SET: SEN0001(thrA) SEN3891(metL)
SES: SARI_02990(thrA) SARI_03555(metL)
STM: STM0002(thrA) STM4101(metL)
YPE: YPO0116(metL) YPO0459(thrA)
YPK: y0303(metL) y3718(thrA)
YPM: YP_0118(metL) YP_3723(thrA)
YPA: YPA_0265(metL) YPA_4051(thrA)
YPN: YPN_0331(thrA) YPN_3738
YPG: YpAngola_A0808(thrA) YpAngola_A3806(metL)
YPP: YPDSF_3174(thrA) YPDSF_3791(metL)
YPS: YPTB0106(metL) YPTB0602(thrA)
YPI: YpsIP31758_0122(metL) YpsIP31758_3476(thrA)
YPY: YPK_3604(thrA) YPK_4094(metL)
YPB: YPTS_0109(metL) YPTS_0626(thrA)
YEN: YE0112(metL) YE0600(thrA)
SFL: SF0002(thrA) SF4018(metL)
SFX: S0002(thrA) S3729(metL)
SFV: SFV_0001(thrA) SFV_4010(metL)
SSN: SSON_0002(thrA) SSON_4114(metL)
SBO: SBO_0001(thrA) SBO_3960(metL)
SBC: SbBS512_E0002(thrA) SbBS512_E4426(metL)
SDY: SDY_0002(thrA) SDY_3775(metL)
ECA: ECA3891(thrA) ECA4251(metL)
PCT: PC1_0178 PC1_3668
PWA: Pecwa_0190 Pecwa_3863
ETA: ETA_01280(metL) ETA_06980(thrA)
PLU: plu0563(thrA) plu4755(metL)
PAY: PAU_00533(thrA) PAU_04243(metL)
BUC: BU194(thrA)
BAS: BUsg188(thrA)
BAB: bbp183(thrA)
BCC: BCc_127(thrA)
BAP: BUAP5A_191(thrA)
BAU: BUAPTUC7_193(thrA)
WBR: WGLp591(thrA)
SGL: SG0404(thrA)
ENT: Ent638_0564(thrA) Ent638_4034(metL)
ESA: ESA_03335(thrA) ESA_03821(metL)
CTU: Ctu_01810(metL) Ctu_06300(thrA)
KPN: KPN_00002(thrA) KPN_04234(metL)
KPE: KPK_4755(thrA) KPK_5445(metL)
KPU: KP1_0096(metL) KP1_0820(thrA)
CKO: CKO_03054(metL) CKO_03385(thrA)
SPE: Spro_0683(thrA) Spro_4785(metL)
PMR: PMI0001(thrA) PMI3224(metL)
EIC: NT01EI_0659 NT01EI_3806
ETR: ETAE_0565(thrA) ETAE_3429
BFL: Bfl111(thrA)
BPN: BPEN_115(thrA)
HDE: HDEF_1900(thrA)
DDA: Dd703_0572 Dd703_3790
DDC: Dd586_3603 Dd586_3932
DZE: Dd1591_0121 Dd1591_0533
HIN: HI0089(thrA)
HIT: NTHI0167(thrA)
HIP: CGSHiEE_02840(thrA)
HAP: HAPS_1271(thrA)
HSO: HS_1214(thrA)
HSM: HSM_0349(thrA)
PMU: PM0113(thrA)
MSU: MS1703(thrA)
APL: APL_0250(thrA)
APA: APP7_0252(thrA)
ASU: Asuc_0801(thrA)
AAT: D11S_1497
XFA: XF2225(thrA)
XFT: PD1273(thrA)
XFM: Xfasm12_1425(thrA)
XFN: XfasM23_1358(thrA)
XCC: XCC1800(thrA) XCC2855
XCB: XC_1253 XC_2389(thrA)
XCA: xccb100_1299 xccb100_2087(thrA)
XCV: XCV1866(thrA) XCV3175(metL)
XAC: XAC1820(thrA) XAC3038
XOO: XOO1820 XOO2242(thrA)
XOM: XOO_1718 XOO_2107(thrA)
XOP: PXO_00814(thrA) PXO_01682
SML: Smlt2156(thrA) Smlt3633(thrA)
SMT: Smal_1749(thrA) Smal_3049
VCH: VC2364(thrA) VC2684(metL)
VCO: VC0395_A1943(thrA) VC0395_A2257(metL)
VCM: VCM66_2287(thrA) VCM66_2604(metL)
VCJ: VCD_001684 VCD_001985
VVU: VV1_0545(thrA) VV1_1365(metL)
VVY: VV0650(thrA) VV3007(metL)
VPA: VP0494(thrA) VP2764(metL)
VHA: VIBHAR_00048(metL) VIBHAR_00939(thrA)
VSP: VS_0483(thrA) VS_2893(metL)
VEX: VEA_002307 VEA_004457
VFI: VF_2118(thrA) VF_2266(metL)
VFM: VFMJ11_2224(thrA) VFMJ11_2378(metL)
VSA: VSAL_I2556(thrA) VSAL_I2748(metL)
PPR: PBPRA0262(metL) PBPRA0552(thrA)
PAE: PA3736(hom)
PAU: PA14_16070(hom)
PAP: PSPA7_1383(hom)
PAG: PLES_12441(hom)
PPU: PP_0664 PP_1470(hom)
PPF: Pput_0698 Pput_4251
PPG: PputGB1_1075
PPW: PputW619_4149
PST: PSPTO_1480(hom)
PSB: Psyr_1290
PSP: PSPPH_1360(hom)
PFL: PFL_1103(hom) PFL_3809(hom)
PFO: Pfl01_1027
PFS: PFLU2011 PFLU5006
PEN: PSEEN4252(hom)
PMY: Pmen_2012 Pmen_3394
PSA: PST_1198(hom)
CJA: CJA_1439(hom)
AVN: Avin_39490(hom)
PAR: Psyc_0253(hom)
PCR: Pcryo_0279
PRW: PsycPRwf_2010
ACI: ACIAD0264(hom)
ACB: A1S_0239 A1S_1711
ABM: ABSDF1940 ABSDF3294(hom)
ABY: ABAYE1937 ABAYE3530(hom)
ABC: ACICU_00262 ACICU_01746
ABN: AB57_0328 AB57_1939
ABB: ABBFA_001785 ABBFA_003293
SON: SO_3415(thrA) SO_4055(metL)
SDN: Sden_0616(metL) Sden_2740(thrA)
SFR: Sfri_2906(thrA) Sfri_3550(metL)
SAZ: Sama_0905(thrA) Sama_3170(metL)
SBL: Sbal_1227(thrA) Sbal_3775
SBM: Shew185_0537(metL) Shew185_1271(thrA)
SBN: Sbal195_0561(metL) Sbal195_1304(thrA)
SBP: Sbal223_0565(metL) Sbal223_3086(thrA)
SLO: Shew_0521 Shew_1079(thrA)
SPC: Sputcn32_0617(metL) Sputcn32_2735(thrA)
SSE: Ssed_1175(thrA) Ssed_4040(metL)
SPL: Spea_0561(metL) Spea_1066(thrA)
SHE: Shewmr4_1138(thrA) Shewmr4_3438(metL)
SHM: Shewmr7_0513(metL) Shewmr7_1209(thrA)
SHN: Shewana3_1139(thrA) Shewana3_3613(metL)
SHW: Sputw3181_1277(thrA) Sputw3181_3553
SHL: Shal_0623(metL) Shal_1114(thrA)
SWD: Swoo_0623(metL) Swoo_1270(thrA)
SWP: swp_3750(thrA) swp_4556(metL)
ILO: IL2466(metL)
CPS: CPS_0456(metL) CPS_4291(thrA)
PHA: PSHAa2379(thrA) PSHAa2722(metL)
PAT: Patl_3580(thrA)
SDE: Sde_1209
MAQ: Maqu_2274
AMC: MADE_03328(thrA)
PIN: Ping_1275(thrA)
TTU: TERTU_0469 TERTU_1164
MCA: MCA0597(hom)
FTW: FTW_1648
FTA: FTA_0521
FTM: FTM_0581(thrA)
FTN: FTN_0525(thrA)
FPH: Fphi_0313
TCX: Tcr_1251
NOC: Noc_2454
AEH: Mlg_1822
HHA: Hhal_0125
TGR: Tgr7_1439
HNA: Hneap_1393
HCH: HCH_01779(thrA)
CSA: Csal_3010
ABO: ABO_0806(hom)
MMW: Mmwyl1_3765
AHA: AHA_0590(metL) AHA_3018(thrA)
ASA: ASA_3040(thrA) ASA_3796(metL)
TAU: Tola_0129 Tola_0621
AFE: Lferr_0633
AFR: AFE_0473(metM)
CRP: CRP_121
RMA: Rmag_0769
VOK: COSY_0706(thrA)
KKO: Kkor_1611
NMA: NMA1395(hom)
NME: NMB1228(metM)
NMC: NMC1128(hom)
NMN: NMCC_1109(hom)
NMI: NMO_1040(hom)
NGO: NGO0779
NGK: NGK_1097
CVI: CV_0996(metL)
LHK: LHK_00589(metL)
RSO: RSc1327
RPI: Rpic_1202
RPF: Rpic12D_1263
REU: Reut_A1993
REH: H16_A2266(thrA)
RME: Rmet_1966
CTI: RALTA_A1810(hom)
BMA: BMA1385(hom)
BMV: BMASAVP1_A1875(hom)
BML: BMA10229_A0022(hom)
BMN: BMA10247_1147(hom)
BPS: BPSL1477(hom)
BPM: BURPS1710b_2396(hom)
BPL: BURPS1106A_2270(hom)
BPD: BURPS668_2232(hom)
BPR: GBP346_A2340
BTE: BTH_I2198
BVI: Bcep1808_1781
BUR: Bcep18194_A5155
BCN: Bcen_6225
BCH: Bcen2424_1854
BCM: Bcenmc03_1878 Bcenmc03_6797
BCJ: BCAL1926(hom)
BAM: Bamb_1792 Bamb_4289
BAC: BamMC406_1764 BamMC406_4844
BMU: Bmul_1419
BMJ: BMULJ_01824(thrA)
BXE: Bxe_A2381
BPH: Bphy_0931
BPY: Bphyt_1806
BGL: bglu_1g14150 bglu_2g03030
PNU: Pnuc_0438
PNE: Pnec_0445
BPE: BP2784
BPA: BPP2479
BBR: BB1926
BPT: Bpet2747(hom)
BAV: BAV2163(hom)
RFR: Rfer_1912
POL: Bpro_2190 Bpro_5333
PNA: Pnap_2231
AAV: Aave_0011 Aave_1238
AJS: Ajs_3206 Ajs_4155
VEI: Veis_2663
DAC: Daci_5219
DIA: Dtpsy_0012 Dtpsy_2559
VAP: Vapar_1831
CTT: CtCNB1_1023
MPT: Mpe_A1541
HAR: HEAR2150(hom)
MMS: mma_1312(thrA)
LCH: Lcho_2025
NEU: NE2369
NET: Neut_0865
NMU: Nmul_A1551
EBA: ebA4952(thrA)
AZO: azo2081(hom)
DAR: Daro_2386
TBD: Tbd_0843
MFA: Mfla_0904 Mfla_1048
MMB: Mmol_1533
MEI: Msip34_0875
APP: CAP2UW1_0892
HPY: HP0822
HPJ: jhp0761(hom)
HPA: HPAG1_0808
HPS: HPSH_02695
HPG: HPG27_781(uvrC)
HPP: HPP12_0829(hom)
HPB: HELPY_0534(hom)
HHE: HH1750(hom)
HAC: Hac_0726(hom)
WSU: WS0450(HOM)
TDN: Suden_1904
CJE: Cj0149c(hom)
CJR: CJE0145(hom)
CJJ: CJJ81176_0185(hom)
CJU: C8J_0146(hom)
CJD: JJD26997_0164(hom)
CFF: CFF8240_0293
CCV: CCV52592_0834
CHA: CHAB381_0217
CCO: CCC13826_1144
CLA: Cla_1414(hom)
ABU: Abu_0158(hom)
SDL: Sdel_0169
NIS: NIS_1553
SUN: SUN_0225
NAM: NAMH_0468
GSU: GSU1693(hom)
GME: Gmet_1629
GUR: Gura_2178
GLO: Glov_1214
GBM: Gbem_3019
GEO: Geob_2680
GEM: GM21_1231
PCA: Pcar_1451
PPD: Ppro_1294
DVU: DVU0890(hom)
DVL: Dvul_2094
DVM: DvMF_1412
DDE: Dde_2731
DDS: Ddes_2314
DMA: DMR_28990(hom)
DSA: Desal_2440
DBA: Dbac_3388
DRT: Dret_1929
DPS: DP1732
DOL: Dole_0291
DAL: Dalk_0711
DAT: HRM2_13560(hom)
ADE: Adeh_1638 Adeh_3931
ACP: A2cp1_2310 A2cp1_4072
AFW: Anae109_2173
ANK: AnaeK_2222 AnaeK_4040
MXA: MXAN_0971 MXAN_2278
SCL: sce4845(hom)
HOH: Hoch_2251
SAT: SYN_00890
SFU: Sfum_1218
PUB: SAR11_0852 SAR11_1025(hom)
MLO: mll0934
MES: Meso_1922
PLA: Plav_2946
SME: SMc00293(thrA)
SMD: Smed_1453
ATU: Atu1588(hom)
ATC: AGR_C_2919
ARA: Arad_2162(thrA)
AVI: Avi_2279(hom)
RET: RHE_CH01878(thrA)
REC: RHECIAT_CH0001964(thrA)
RLE: RL2097(hom) pRL80071(hom)
RLT: Rleg2_1545 Rleg2_5063
RLG: Rleg_1739
RHI: NGR_b07030(thrA) NGR_c14020(thrA)
LAS: CLIBASIA_03995(thrA)
BME: BMEI0725
BMF: BAB1_1293
BMB: BruAb1_1275(hom)
BMC: BAbS19_I12070
BMS: BR1274(hom)
BMT: BSUIS_A1323
BOV: BOV_1237(hom)
BCS: BCAN_A1295
BMR: BMI_I1285(hom)
OAN: Oant_1917
BJA: blr4362(hom)
BRA: BRADO3572(hom)
BBT: BBta_3996(hom)
RPA: RPA2504(HDH)
RPB: RPB_2966
RPC: RPC_2816
RPD: RPD_2495
RPE: RPE_2937
RPT: Rpal_2783
NWI: Nwi_1647
NHA: Nham_2309
OCA: OCAR_6016
BHE: BH10030(metM)
BTR: Btr_1379(hom)
BGR: Bgr_12260(hom)
XAU: Xaut_3521
AZC: AZC_1848
MEX: Mext_1967
MEA: Mex_1p1941(hom)
MDI: METDI2730(hom)
MRD: Mrad2831_2919
MET: M446_2698
MPO: Mpop_1922
MCH: Mchl_2243
MNO: Mnod_3264
BID: Bind_1387
MSL: Msil_2074
CCR: CC_1383
CCS: CCNA_01447
CAK: Caul_3015
PZU: PHZ_c1643(hom)
SIL: SPO1734(hom)
SIT: TM1040_2164
RSP: RSP_0403
RSH: Rsph17029_2057
RSQ: Rsph17025_0834
RSK: RSKD131_1734
JAN: Jann_2998
RDE: RD1_2538(hom)
PDE: Pden_3678
DSH: Dshi_2273
MMR: Mmar10_1098 Mmar10_2618
HNE: HNE_2310(hom)
HBA: Hbal_1864
ZMO: ZMO0483
ZMN: Za10_0771
NAR: Saro_0019
SAL: Sala_0810
SWI: Swit_4731
ELI: ELI_13775
GOX: GOX1517
GBE: GbCGDNIH1_1434
ACR: Acry_1298
GDI: GDI_1033
GDJ: Gdia_2504
APT: APA01_21340
RRU: Rru_A2410
RCE: RC1_1305(hom)
MAG: amb3728
MGM: Mmc1_1756
BSU: BSU32260(hom)
BHA: BH1253 BH1737 BH3422(hom)
BAN: BA1968(hom-1) BA2608 BA5654(hom-2)
BAR: GBAA1968(hom-1) GBAA2608 GBAA5654(hom-2)
BAA: BA_0512 BA_2468 BA_3119
BAT: BAS1825 BAS2433 BAS5256
BAH: BAMEG_1987 BAMEG_2623(hom1) BAMEG_5698(hom2)
BAI: BAA_2036(hom1) BAA_2671 BAA_5681(hom2)
BCE: BC1964 BC2548 BC5404
BCA: BCE_2051(hom) BCE_2626 BCE_5533(hom)
BCZ: BCZK1782(hom) BCZK2354(hom) BCZK5102(hom)
BCR: BCAH187_A2073(hom1) BCAH187_A2664 BCAH187_A5583(hom2)
BCB: BCB4264_A1970(hom1) BCB4264_A2580 BCB4264_A5527(hom2)
BCU: BCAH820_2002(hom1) BCAH820_2625 BCAH820_5499
BCG: BCG9842_B2743 BCG9842_B3357(hom1) BCG9842_B5424(hom2)
BCQ: BCQ_1957(hom) BCQ_2482(hom) BCQ_5246(hom)
BCX: BCA_2030(hom1) BCA_2698 BCA_5556
BCY: Bcer98_1496 Bcer98_3923
BTK: BT9727_1799(hom) BT9727_2388(hom) BT9727_5085(hom)
BTL: BALH_1741(hom) BALH_2348(hom) BALH_4905(hom)
BWE: BcerKBAB4_1833 BcerKBAB4_2526 BcerKBAB4_5197
BLI: BL02137(hom)
BLD: BLi03414(hom)
BCL: ABC0023 ABC1578 ABC2942(hom)
BAY: RBAM_029370(hom)
BPU: BPUM_2888(thrA)
OIH: OB0466
GKA: GK2964
GTN: GTNG_2268 GTNG_2914
GWC: GWCH70_2896
GYM: GYMC10_1550
GYC: GYMC61_3041
AFL: Aflv_2414(hom)
SAU: SA1164(dhoM)
SAV: SAV1328(dhoM)
SAW: SAHV_1317(dhoM)
SAM: MW1215(dhoM)
SAR: SAR1338
SAS: SAS1268
SAC: SACOL1362(hom)
SAB: SAB1186
SAA: SAUSA300_1226
SAX: USA300HOU_1273(thrA)
SAO: SAOUHSC_01320
SAJ: SaurJH9_1389
SAH: SaurJH1_1416
SAE: NWMN_1240(metL)
SAD: SAAV_1308
SEP: SE1009
SER: SERP0897(hom)
SHA: SH1579(dhoM)
SSP: SSP1438
SCA: Sca_0970(hom)
LMO: lmo2547(hom)
LMF: LMOf2365_2520(hom)
LMH: LMHCC_0050
LMC: Lm4b_02516(hom)
LIN: lin2691
LWE: lwe2496(hom)
LSP: Bsph_0843
MCL: MCCL_0985
BBE: BBR47_18540(hom) BBR47_30190 BBR47_30780
PJD: Pjdr2_4407
AAC: Aaci_2233
LLA: L0090(hom)
LLK: LLKF_1185(hom)
LLC: LACR_1280
LLM: llmg_1332(hom)
SPN: SP_1361
SPD: SPD_1195(hom)
SPR: spr1219(hom)
SPW: SPCG_1350(hom)
SPX: SPG_1302(metM)
SNE: SPN23F_13270(hom)
SPV: SPH_1493
SNM: SP70585_1400
SJJ: SPJ_1261
SPP: SPP_1381
SAG: SAG1120(hom)
SAN: gbs1187
SAK: SAK_1205(hom)
SMU: SMU.965
STC: str0469(hom)
STL: stu0469(hom)
STE: STER_0506
SSA: SSA_1043(hom)
SSU: SSU05_0801
SSV: SSU98_0801
SSB: SSUBM407_1086(hom)
SSI: SSU0747(hom)
SSS: SSUSC84_0712(hom)
SGO: SGO_0801(hom)
SEQ: SZO_08990
SEZ: Sez_1067(hom)
SEU: SEQ_1121
SUB: SUB0810(hom)
SDS: SDEG_0858
LPL: lp_0571(hom2) lp_2535(hom1)
LPJ: JDM1_0468(hom2) JDM1_2041(hom1)
LAC: LBA1212
LSL: LSL_1519(thrA)
LDB: Ldb1350
LBU: LBUL_1259
LCA: LSEI_2151
LCB: LCABL_23330(thrA)
LGA: LGAS_1075
LFE: LAF_1145
LRH: LGG_02155(thrA)
LRL: LC705_02162(thrA)
EFA: EF2422(hom)
OOE: OEOE_1546
LME: LEUM_0786
LCI: LCK_00723(hom)
CAC: CAC0998
CTC: CTC00886 CTC02355
CNO: NT01CX_0896
CTH: Cthe_0290 Cthe_1376
CDF: CD1166(hom1) CD1580(hom2)
CDC: CD196_1025(hom1) CD196_1502(hom2)
CDL: CDR20291_1003(hom1) CDR20291_1477(hom2)
CBO: CBO1641(hom) CBO1875(hom)
CBA: CLB_1658(hom-1) CLB_1812(hom-2)
CBH: CLC_1667(hom-1) CLC_1819(hom-2)
CBY: CLM_1882(hom) CLM_2091(hom)
CBL: CLK_1105(hom) CLK_1265(hom)
CBK: CLL_A1041(hom)
CBB: CLD_2762(hom) CLD_2914(hom)
CBI: CLJ_B1750(hom_1) CLJ_B2061(hom_2)
CBT: CLH_0975(hom)
CBF: CLI_1718(hom-1) CLI_1939(hom-2)
CBE: Cbei_1551
CKL: CKL_0859(hom1) CKL_1105(hom2)
CKR: CKR_0772 CKR_1006
CPY: Cphy_3603
CCE: Ccel_1452
AMT: Amet_0566
AOE: Clos_2186
STH: STH2739
SWO: Swol_1319
VPR: Vpar_0899
ATE: Athe_1959
DSY: DSY1363
DHD: Dhaf_2479
DRM: Dred_1165
DAE: Dtox_2114
PTH: PTH_1601(thrA)
DAU: Daud_1073
HMO: HM1_1936(thrA)
FMA: FMG_0319
EEL: EUBELI_00370 EUBELI_01437
ERE: EUBREC_0724
TTE: TTE2620(thrA2)
TEX: Teth514_2311
TPD: Teth39_0140
CHY: CHY_1912(hom)
MTA: Moth_1307
ADG: Adeg_0882
CSC: Csac_0993
NTH: Nther_0669
HOR: Hore_08020
MTU: Rv1294(thrA)
MTC: MT1333(thrA)
MRA: MRA_1302(thrA)
MTF: TBFG_11321
MTB: TBMG_02686(TBMG_02686.1)
MBO: Mb1326(thrA)
MBB: BCG_1354(thrA)
MBT: JTY_1329(thrA)
MLE: ML1129(hom)
MLB: MLBr_01129(hom)
MPA: MAP2468c(thrA)
MAV: MAV_1509
MSM: MSMEG_4957
MUL: MUL_3970(thrA)
MVA: Mvan_4348
MGI: Mflv_2298
MAB: MAB_1435
MMC: Mmcs_3896
MKM: Mkms_3970
MJL: Mjls_3882
MMI: MMAR_4103(thrA)
CGL: NCgl1136(cgl1183)
CGB: cg1337(hom)
CGT: cgR_1262
CEF: CE1289
CDI: DIP1036(thrA)
CJK: jk1352(hom)
CUR: cur_0694
CAR: cauri_1049(hom)
CKP: ckrop_1290
NFA: nfa10490(thrA)
RHA: RHA1_ro01488(thrA)
RER: RER_39220(hom)
ROP: ROP_11980
GBR: Gbro_1901
SCO: SCO0420(SCF51.19c) SCO5354(SCBAC5H2.23)
SMA: SAV_2918(thrA)
SGR: SGR_2182
TWH: TWT439(thrA)
TWS: TW329(hom)
LXX: Lxx06870(thrA)
CMI: CMM_1153(thrA)
CMS: CMS_1477
ART: Arth_2623 Arth_3560
AAU: AAur_2612(thrA)
ACH: Achl_2356
RSA: RSal33209_1429
KRH: KRH_09640(hom)
MLU: Mlut_08020
BCV: Bcav_1281
BFA: Bfae_19340
JDE: Jden_1790
KSE: Ksed_14810
XCE: Xcel_2465
PAC: PPA1258
NCA: Noca_1744
TFU: Tfu_2424
TCU: Tcur_3939
SRO: Sros_1638
FRA: Francci3_3725
FRE: Franean1_1005
FAL: FRAAL5951(hom)
ACE: Acel_0630
NML: Namu_2095
KRA: Krad_1252
SEN: SACE_2236 SACE_6298(thrA)
SVI: Svir_29960
AMI: Amir_6156
STP: Strop_3651
SAQ: Sare_4033
CAI: Caci_1199
BLO: BL1274(thrA)
BLJ: BLD_1607(thrA)
BLN: Blon_2316
BAD: BAD_1416(thrA)
BLA: BLA_0616(thrA)
BLC: Balac_1415
BLT: Balat_1415
RXY: Rxyl_1091
AFO: Afer_1813
CCU: Ccur_01680
SHI: Shel_26330
APV: Apar_0540
ELE: Elen_0280
LIL: LA3638(thrA)
LIC: LIC10571(hom)
LBJ: LBJ_2852(thrA)
LBL: LBL_0219(thrA)
LBI: LEPBI_I0064(hom)
LBF: LBF_0064(thrA)
BHY: BHWA1_00358
ABA: Acid345_1481 Acid345_4165
ACA: ACP_0317
SUS: Acid_0526 Acid_7030
BTH: BT_2403(thrA)
BFR: BF0608(thrA)
BFS: BF0558(thrA)
BVU: BVU_2050(thrA)
PDI: BDI_0261(thrA)
APS: CFPG_657(thrA)
SRU: SRU_0482 SRU_0691(thrA)
RMR: Rmar_2222
CHU: CHU_0073(thrA)
DFE: Dfer_3152
CPI: Cpin_1962 Cpin_5429
PHE: Phep_1873 Phep_3804
GFO: GFO_0318(hom) GFO_1970(thrA)
FJO: Fjoh_1492 Fjoh_1494 Fjoh_2575(thrA)
FPS: FP0255
COC: Coch_0411
RBI: RB2501_12949
SMG: SMGWSS_141(thrA)
SMS: SMDSEM_149(thrA)
BBL: BLBBGE_501(thrA)
BPI: BPLAN_138(thrA)
FSU: Fisuc_2253
LBA: Lebu_0845
STR: Sterm_3015
OTE: Oter_2235
MIN: Minf_0747(thrA)
AMU: Amuc_1964
GAU: GAU_1367
RBA: RB8510(hom)
EMI: Emin_0284 Emin_0860
RSD: TGRD_569
TAI: Taci_0506
SYN: sll0455(thrA)
SYW: SYNW0711(thrA)
SYC: syc2003_c(thrA)
SYF: Synpcc7942_2090
SYD: Syncc9605_1957
SYE: Syncc9902_0704
SYG: sync_0941(hom)
SYR: SynRCC307_0723(thrA)
SYX: SynWH7803_1606(thrA)
SYP: SYNPCC7002_A2131(hom)
CYA: CYA_1100(hom)
CYB: CYB_1425(hom)
TEL: tll0277(thrA)
MAR: MAE_45060(thrA)
CYT: cce_2359(thrA)
CYP: PCC8801_0799
CYC: PCC7424_0286
CYN: Cyan7425_4262
CYH: Cyan8802_0827
GVI: gvip559(thrA)
ANA: all4120(thrA)
NPU: Npun_R2750
AVA: Ava_0783
PMA: Pro1150(thrA)
PMM: PMM1051(thrA)
PMT: PMT1143(thrA)
PMN: PMN2A_0702
PMI: PMT9312_1062
PMB: A9601_11561(thrA)
PMC: P9515_11421(thrA)
PMF: P9303_08881(thrA)
PMG: P9301_11571(thrA)
PMH: P9215_11861(thrA)
PMJ: P9211_11401(thrA)
PME: NATL1_15361(thrA)
TER: Tery_4567
AMR: AM1_2061(thrA)
CTE: CT2030(thrA)
CPC: Cpar_1907(thrA)
CCH: Cag_0142(thrA)
CPH: Cpha266_2542(thrA)
CPB: Cphamn1_0299(thrA)
CLI: Clim_2330(thrA)
PVI: Cvib_1626(thrA)
PLT: Plut_1983(thrA)
PPH: Ppha_2703(thrA)
PAA: Paes_0264(thrA)
CTS: Ctha_1361(thrA)
DET: DET1206(metM)
DEH: cbdb_A1123(metM)
DEB: DehaBAV1_1016
DEV: DhcVS_989(metM)
RRS: RoseRS_1971 RoseRS_2987
RCA: Rcas_1559 Rcas_2086
CAU: Caur_1922
CAG: Cagg_2574
CHL: Chy400_2076
TRO: trd_0367
STI: Sthe_1548
DRA: DR_1278
DGE: Dgeo_0610
DDR: Deide_15930
TTH: TTC0115
TTJ: TTHA0489
AAE: aq_1812(thrA)
HYA: HY04AAS1_1413
SUL: SYO3AOP1_0498
SAF: SULAZ_0413
PMX: PERMA_1054
TMA: TM0547
TPT: Tpet_0373
TLE: Tlet_1364
TRQ: TRQ2_0390
TNA: CTN_0121
TNP: Tnap_0327
PMO: Pmob_1153
DTH: DICTH_1252
DTU: Dtur_1366
TYE: THEYE_A1986
MJA: MJ1602
MFE: Mefer_0316
MVU: Metvu_1166
MMP: MMP1702(hom)
MMQ: MmarC5_1704
MMX: MmarC6_0969
MMZ: MmarC7_0977
MAE: Maeo_1209
MVN: Mevan_1004
MAC: MA2572
MBA: Mbar_A1898
MMA: MM_2713
MBU: Mbur_1087
MTP: Mthe_0845
MHU: Mhun_2292
MLA: Mlab_0481
MEM: Memar_0971
MBN: Mboo_1354
MPL: Mpal_1993
MPD: MCP_1713
MTH: MTH1232 MTH417
MST: Msp_0487
MSI: Msm_0154
MKA: MK1554(thrA)
AFU: AF0935(hom)
HAL: VNG2650G(hom)
HSL: OE4722R(hom)
HMA: rrnAC2408(hom)
HWA: HQ3386A(hom)
NPH: NP0302A(hom)
HLA: Hlac_0155
HUT: Huta_0812
HMU: Hmuk_0498
TAC: Ta1179
TVO: TVN0385
PTO: PTO1417
PHO: PH1075
PAB: PAB0610(hom)
PFU: PF1104
TKO: TK1627
TON: TON_0036
TGA: TGAM_2031(hom)
TSI: TSIB_1477
RCI: LRC427(thrA)
APE: APE_1144.1(hom)
SSO: SSO0657(thrA)
STO: ST1519
SAI: Saci_1636(hdh)
SIS: LS215_1587
SIA: M1425_1479
SIM: M1627_1594
SID: M164_1476
SIY: YG5714_1483
SIN: YN1551_1353
MSE: Msed_2003
PAI: PAE2868
PIS: Pisl_0271
PCL: Pcal_0379
PAS: Pars_0949
CMA: Cmaq_0731
TNE: Tneu_1842
NMR: Nmar_0696
KCR: Kcr_0008
 |
|---|
| Structures |
PDB: 1EBF 1EBU 1Q7G 1TVE 2EJW |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:14353905]
BLACK S, WRIGHT NG.
Homoserine dehydrogenase.
J. Biol. Chem. 213 (1955) 51-60.
Saccharomyces cerevisiae [GN:sce] |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:4551091]
Starnes WL, Munk P, Maul SB, Cunningham GN, Cox DJ, Shive W.
Threonine-sensitive aspartokinase-homoserine dehydrogenase complex,
amino acid composition, molecular weight, and subunit composition of
the complex.
Biochemistry. 11 (1972) 677-87.
Escherichia coli [GN:eco] |
|---|
Reference
Authors
Title
Journal
Organism
|
3 [PMID:4562990]
Veron M, Falcoz-Kelly F, Cohen GN.
The threonine-sensitive homoserine dehydrogenase and aspartokinase
activities of Escherichia coli K12. The two catalytic activities are
carried by two independent regions of the polypeptide chain.
Eur. J. Biochem. 28 (1972) 520-7.
Escherichia coli [GN:eco] |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 1.1.1.3
IUBMB Enzyme Nomenclature: 1.1.1.3
ExPASy - ENZYME nomenclature database: 1.1.1.3
BRENDA, the Enzyme Database: 1.1.1.3
CAS: 9028-13-1 |
|---|
