KEGG   ENZYME: 1.1.1.36Help
Entry
EC 1.1.1.36                 Enzyme                                 
Name acetoacetyl-CoA reductase;
acetoacetyl coenzyme A reductase;
hydroxyacyl coenzyme-A dehydrogenase;
NADP-linked acetoacetyl CoA reductase;
NADPH:acetoacetyl-CoA reductase;
D(-)-beta-hydroxybutyryl CoA-NADP oxidoreductase;
short chain beta-ketoacetyl(acetoacetyl)-CoA reductase;
beta-ketoacyl-CoA reductase;
D-3-hydroxyacyl-CoA reductase;
(R)-3-hydroxyacyl-CoA dehydrogenase
Class Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname (R)-3-hydroxyacyl-CoA:NADP+ oxidoreductase
Reaction(IUBMB) (R)-3-hydroxyacyl-CoA + NADP+ = 3-oxoacyl-CoA + NADPH + H+
[RN:R01779]
Reaction(KEGG) R01779 > R01977
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Substrate (R)-3-hydroxyacyl-CoA [CPD:C01086];
NADP+ [CPD:C00006]
Product 3-oxoacyl-CoA [CPD:C00264];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Pathway PATH: ec00650  Butanoate metabolism
Orthology KO: K00023  acetoacetyl-CoA reductase
Genes XFA: XF0319(fabG)
XFT: PD0262(fabG)
XFM: Xfasm12_0283(fabG)
XFN: XfasM23_0254(fabG)
XCC: XCC2294(phbB) XCC3355(fabG)
XCB: XC_0809(fabG) XC_1821
XCA: xccb100_0842(fabG) xccb100_1884
XCV: XCV2598(phbB) XCV3614(fabG)
XAC: XAC2401(phbB) XAC3486(fabG)
XOO: XOO1102(fabG) XOO2728(phbB)
XOM: XOO_1000(fabG) XOO_2573
XOP: PXO_00406 PXO_02411(fabG)
SML: Smlt3325(phbB) Smlt3952(fabG)
SMT: Smal_2750 Smal_3362(fabG)
VCH: VCA0691
VCO: VC0395_0631
VCM: VCM66_A0649
VCJ: VCD_000634
VVU: VV2_0742
VVY: VVA1211
VPA: VPA1205
VHA: VIBHAR_05365
VSP: VS_II0584
VEX: VEA_000520
PPR: PBPRB0350(fabG) PBPRB1841
PSA: PST_0685(phaB)
AVN: Avin_23650(phbB)
SON: SO_3263
SAZ: Sama_2250
CPS: CPS_2625(phbB1) CPS_4092(phbB2)
SDE: Sde_1330
MAQ: Maqu_3915
TTU: TERTU_2753(phbB)
LPN: lpg0560(phaB) lpg0561(phaB) lpg1059(phaB)
LPF: lpl0603 lpl0604 lpl1056 lpl2305
LPP: lpp0620 lpp0621 lpp2322
LPC: LPC_2098 LPC_2215(phaB) LPC_2738(phaB2) LPC_2739(phaB)
AEH: Mlg_0994(fabG) Mlg_2486
HHA: Hhal_0557 Hhal_2205
TGR: Tgr7_1515 Tgr7_1519
HCH: HCH_04996(phbB)
CSA: Csal_3029
AHA: AHA_1951
ASA: ASA_2343
TAU: Tola_2469
CVI: CV_2364(phaB)
LHK: LHK_01110(phaB)
RSO: RSc1633(phbB)
RPI: Rpic_1914 Rpic_4412
RPF: Rpic12D_1585 Rpic12D_4545
REU: Reut_A1349 Reut_B3865 Reut_B4127 Reut_C6018
REH: H16_A1439(phaB1) H16_A2002(phaB2) H16_A2171(phaB3)
RME: Rmet_1333 Rmet_1358 Rmet_5123
CTI: RALTA_A1352(phaB1) RALTA_A1758(phaB2)
BMA: BMA1320(phbB-1) BMAA0166(phbB-2)
BMV: BMASAVP1_1337(phbB-1) BMASAVP1_A1809(phbB-2)
BML: BMA10229_A0087(phbB-1)
BMN: BMA10247_1080(phbB-2) BMA10247_A0193(phbB-1)
BPS: BPSL1536(phbB) BPSS1916(phbB)
BPM: BURPS1710b_2329(phbB-1) BURPS1710b_A1014(phbB-2)
BPL: BURPS1106A_2201(phbB) BURPS1106A_A2601(phbB)
BPD: BURPS668_2164(phbB) BURPS668_A2744(phbB)
BPR: GBP346_A2272(phbB)
BTE: BTH_I2257 BTH_II0461
BVI: Bcep1808_1716 Bcep1808_2876 Bcep1808_6164 Bcep1808_6330
BUR: Bcep18194_A5090 Bcep18194_A6101
BCN: Bcen_2157 Bcen_6290
BCH: Bcen2424_1789 Bcen2424_2771
BCM: Bcenmc03_1813 Bcenmc03_2782
BCJ: BCAL0833(phbB) BCAL1861(phbB) BCAM0296(phbB)
BAM: Bamb_1727 Bamb_2823 Bamb_3819
BAC: BamMC406_1700 BamMC406_2690 BamMC406_4287
BMU: Bmul_0544 Bmul_1485 Bmul_5756 Bmul_5895
BMJ: BMULJ_01757(phbB) BMULJ_02716(phbB) BMULJ_05630(phbB)
     BMULJ_05765(phbB)
BXE: Bxe_A2341 Bxe_B0354
BPH: Bphy_0971 Bphy_1131 Bphy_6555
BPY: Bphyt_1845 Bphyt_5566
BGL: bglu_1g14730 bglu_2g20290
PNU: Pnuc_0924(fabG)
PNE: Pnec_0917
BPE: BP1150(fabG)
BPA: BPP3195(fabG)
BBR: BB3595(fabG)
BPT: Bpet1850(fabG)
BAV: BAV1222(fabG)
RFR: Rfer_2560(fabG)
POL: Bpro_1198 Bpro_2141(fabG)
PNA: Pnap_2803(fabG)
AAV: Aave_2479(fabG)
AJS: Ajs_2072(fabG)
VEI: Veis_2347(fabG)
DAC: Daci_3602(fabG)
DIA: Dtpsy_1310 Dtpsy_1895
VAP: Vapar_2031 Vapar_5342
CTT: CtCNB1_2350
MPT: Mpe_A1868(fabG)
HAR: HEAR0578(phbB) HEAR2345(phbB)
MMS: mma_0556(phbB)
LCH: Lcho_2085(fabG)
EBA: ebA4729(phbB) ebA4731(adh)
AZO: azo1022(phbB1) azo1023(phbB2)
DAR: Daro_1609 Daro_1610
TMZ: Tmz1t_1025
APP: CAP2UW1_3919
GBM: Gbem_1433
GEM: GM21_2821
PCA: Pcar_1120
RPR: RP035
RTY: RT0095(phbB)
RCO: RC0054(phbB)
RFE: RF_0153(phbB)
RAK: A1C_00095
RRJ: RrIowa_0072
RAF: RAF_ORF0048(phbB)
RBE: RBE_1370(phbB)
RBO: A1I_07605
MLO: mlr3848
MES: Meso_3375
PLA: Plav_1574 Plav_3449
SME: SMc03878(phbB)
SMD: Smed_3116
ATU: Atu2770(phbB)
ATC: AGR_C_5024(phbB)
ARA: Arad_4680(phbB) Arad_8221(phbB)
AVI: Avi_4345(phbB)
RET: RHE_CH04019(phbB)
REC: RHECIAT_CH0004307(phbB)
RLE: RL4620(phaB)
RLT: Rleg2_3821
RLG: Rleg_4149
RHI: NGR_c32710
BJA: bll0225(phbB) blr3725(phbB)
BRA: BRADO0563(phbB)
BBT: BBta_7613(phbB)
RPA: RPA0532
RPB: RPB_0508
RPC: RPC_0505
RPD: RPD_0305
RPE: RPE_0167
RPT: Rpal_0533
NWI: Nwi_3061
NHA: Nham_3689
OCA: OCAR_4106 OCAR_4863
XAU: Xaut_3107
AZC: AZC_0305
MEX: Mext_3470
MEA: Mex_1p3701(phaB)
MDI: METDI4273(phaB)
MRD: Mrad2831_5119
MET: M446_1247 M446_5281
MPO: Mpop_3668
MCH: Mchl_3778
MNO: Mnod_4780
BID: Bind_0426
MSL: Msil_2997
CCR: CC_0511
CCS: CCNA_00545
CAK: Caul_1946 Caul_4514
PZU: PHZ_c0432(phbB) PHZ_p0110(phbB)
SIL: SPO0325(phbB)
SIT: TM1040_3736
RSP: RSP_0747 RSP_3963
RSH: Rsph17029_2402
RSQ: Rsph17025_2467
RSK: RSKD131_2105
JAN: Jann_0492
RDE: RD1_3395(phbB)
PDE: Pden_2027
DSH: Dshi_3067(fabG1)
MMR: Mmar10_2384
HNE: HNE_3404(phbB)
HBA: Hbal_2358
NAR: Saro_3212
SAL: Sala_2255
SWI: Swit_4599
ELI: ELI_12280
GBE: GbCGDNIH1_0449
ACR: Acry_2753
GDI: GDI_3305
GDJ: Gdia_3065
RRU: Rru_A0273
RCE: RC1_3949(phbB)
MAG: amb0843
MGM: Mmc1_1166
BAN: BA1330(fabG)
BAR: GBAA1330(fabG)
BAA: BA_1853
BAT: BAS1230(fabG)
BAH: BAMEG_3266(phbB)
BAI: BAA_1397(phbB)
BCE: BC1317(fabG)
BCA: BCE_1429(fabG)
BCZ: BCZK1209(fabG)
BCR: BCAH187_A1470(phbB)
BCB: BCB4264_A1368(phbB)
BCU: BCAH820_1405(phbB)
BCG: BCG9842_B3976(phbB)
BCQ: BCQ_1389(phaB)
BCX: BCA_1368(phbB)
BCY: Bcer98_1043
BTK: BT9727_1207(fabG)
BTL: BALH_1179(phaB)
BWE: BcerKBAB4_1231
RXY: Rxyl_2393(fabG)
MAR: MAE_50050(phaB)
CAU: Caur_1462(fabG)
CAG: Cagg_1951
CHL: Chy400_1585
Taxonomy
Structures PDB: 3E9N  3EZL  3GK3  
Reference
  Authors
  Title

  Journal
  Organism
 1  [PMID:14004466]
WAKIL S, BRESSLER R.
Studies on the mechanism of fatty acid synthesis. X. Reduced
triphosphopyridine nucleotide-acetoacetyl coenzyme A reductase.
J. Biol. Chem. 237 (1962) 687-93.
pigeon
Other DBs ExplorEnz - The Enzyme Database: 1.1.1.36
IUBMB Enzyme Nomenclature: 1.1.1.36
ExPASy - ENZYME nomenclature database: 1.1.1.36
UM-BBD (Biocatalysis/Biodegradation Database): 1.1.1.36
BRENDA, the Enzyme Database: 1.1.1.36
CAS: 9028-41-5
DBGET integrated database retrieval system