| Entry |
|
|---|
| Name |
phosphogluconate 2-dehydrogenase;
6-phosphogluconic dehydrogenase;
phosphogluconate dehydrogenase;
gluconate 6-phosphate dehydrogenase;
6-phosphogluconate dehydrogenase (NAD+);
2-keto-6-phosphogluconate reductase |
|---|
| Class |
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
 |
|---|
| Sysname |
6-phospho-D-gluconate:NAD(P)+ 2-oxidoreductase |
|---|
| Reaction(IUBMB) |
6-phospho-D-gluconate + NAD(P)+ = 6-phospho-2-dehydro-D-gluconate +
NAD(P)H + H+ [RN:R02032 R02034] |
|---|
| Reaction(KEGG) |
R02032 R02034
 |
|---|
| Substrate |
6-phospho-D-gluconate [CPD:C00345];
NAD+ [CPD:C00003];
NADP+ [CPD:C00006] |
|---|
| Product |
6-phospho-2-dehydro-D-gluconate [CPD:C01218];
NADH [CPD:C00004];
NADPH [CPD:C00005];
H+ [CPD:C00080] |
|---|
| Pathway |
PATH: ec00030 Pentose phosphate pathway
PATH: ec00480 Glutathione metabolism
PATH: ec01100 Metabolic pathways |
|---|
| Orthology |
KO: K00032 phosphogluconate 2-dehydrogenase |
|---|
| Genes |
PAE: PA2263
PAU: PA14_35320(kguD)
PAP: PSPA7_2977
PPU: PP_3376(kguD)
PPF: Pput_2382
PPG: PputGB1_2568
PPW: PputW619_2571
PFL: PFL_2717
REH: H16_B1813(kguD)
 |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:13894458]
FRAMPTON EW, WOOD WA.
Carbohydrate oxidation by Pseudomonas fluorescens VI. Conversion of
2-keto-6-phosphogluconate to pyruvate.
J. Biol. Chem. 236 (1961) 2571-7.
Pseudomonas fluorescens |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 1.1.1.43
IUBMB Enzyme Nomenclature: 1.1.1.43
ExPASy - ENZYME nomenclature database: 1.1.1.43
BRENDA, the Enzyme Database: 1.1.1.43
CAS: 9001-82-5 |
|---|
