KEGG   ENZYME: 1.1.1.57Help
Entry
EC 1.1.1.57                 Enzyme                                 
Name fructuronate reductase;
mannonate oxidoreductase;
mannonic dehydrogenase;
D-mannonate dehydrogenase;
D-mannonate:NAD+ oxidoreductase
Class Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname D-mannonate:NAD+ 5-oxidoreductase
Reaction(IUBMB) D-mannonate + NAD+ = D-fructuronate + NADH + H+ [RN:R02454]
Reaction(KEGG) R02454
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Substrate D-mannonate [CPD:C00514];
NAD+ [CPD:C00003]
Product D-fructuronate [CPD:C00905];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment Also reduces D-tagaturonate.
Pathway PATH: ec00040  Pentose and glucuronate interconversions
PATH: ec01100  Metabolic pathways
Orthology KO: K00040  fructuronate reductase
Genes ECO: b4323(uxuB)
ECJ: JW4286(uxuB)
EBW: BWG_4021(uxuB)
ECE: Z5921(uxuB)
ECS: ECs5282
ECF: ECH74115_5829(uxuB)
ETW: ECSP_5407(uxuB)
ECG: E2348C_4629(uxuB)
ECC: c5403(uxuB)
ECI: UTI89_C5019(uxuB)
ECP: ECP_4659
ECV: APECO1_2108(uxuB)
ECW: EcE24377A_4921
ECX: EcHS_A4549
ECM: EcSMS35_4850(uxuB)
ECY: ECSE_4596
ECK: EC55989_4988(uxuB)
ECQ: ECED1_5205(uxuB)
ECR: ECIAI1_4539(uxuB)
ECT: ECIAI39_4796(uxuB)
ECZ: ECS88_4941(uxuB)
EUM: ECUMN_4931(uxuB)
ELF: LF82_2404(uxuB)
EBL: B21_04154(uxuB)
EBD: ECBD_3712
EBR: ECB_04192(uxuB)
EOH: ECO103_5104(uxuB)
EOI: ECO111_5179(uxuB)
EOJ: ECO26_5519(uxuB)
EFE: EFER_1533(ydfI) EFER_3029(uxuB)
STY: STY1553 STY3307(uxuB)
STT: t3057(uxuB)
SPT: SPA1347(ydfI) SPA3004(uxuB)
SEK: SSPA1252 SSPA2802
SPQ: SPAB_01802 SPAB_03916
SEI: SPC_2221(ydfI) SPC_3204(uxuB)
SEC: SC1525(ydfI) SC3077(uxuB)
SEH: SeHA_C1678 SeHA_C3382
SEE: SNSL254_A1619 SNSL254_A3388
SEW: SeSA_A1610 SeSA_A3318
SEA: SeAg_B1664 SeAg_B3308
SED: SeD_A1830 SeD_A3481
SEG: SG1611(ydfI) SG3030
SET: SEN1543(ydfI) SEN2979
SES: SARI_01444 SARI_04490
STM: STM1508(ydfI) STM3136
YPE: YPO1280
YPK: y2903
YPM: YP_1309(mtlD1)
YPA: YPA_0998
YPN: YPN_2696
YPG: YpAngola_A1507
YPP: YPDSF_2414
YPS: YPTB1314
YPI: YpsIP31758_2702
YPY: YPK_2779
YPB: YPTS_1406
YEN: YE1438
SFL: SF4197(uxuB)
SFX: S4453(uxuB)
SFV: SFV_4203(uxuB)
SSN: SSON_4478(uxuB)
SBO: SBO_4374(uxuB)
SBC: SbBS512_E4791(uxuB)
ECA: ECA0819(uxuB)
PCT: PC1_0693 PC1_0805
PWA: Pecwa_0928 Pecwa_1039
PLU: plu0175(uxuB)
PAY: PAU_00125(uxuB)
SGL: SG1837
ENT: Ent638_1935 Ent638_2768
ESA: ESA_01067 ESA_01754
CTU: Ctu_21990(ydfI) Ctu_28380(yeiQ)
KPN: KPN_01587(ydfI)
KPE: KPK_1557 KPK_2868
KPU: KP1_2610(ydfI) KP1_3834(yeiQ)
SPE: Spro_3239
EIC: NT01EI_2580
ETR: ETAE_2291
DDA: Dd703_0976 Dd703_2638
DDC: Dd586_0689 Dd586_2942
DZE: Dd1591_1267 Dd1591_3363
ASU: Asuc_0371
XCC: XCC4107(mtlD)
XCB: XC_4198
XCA: xccb100_4312(uxuB)
XCV: XCV4338(mtlD)
XAC: XAC4232(mtlD)
XOO: XOO4424(mtlD)
XOM: XOO_4167
XOP: PXO_03857
VVU: VV2_1069
VVY: VVA1593
VPA: VPA1705
PPR: PBPRB1880
PSP: PSPPH_2593(uxuB)
PFO: Pfl01_2636
CJA: CJA_0180
PHA: PSHAb0208(uxuB)
AMC: MADE_01746
PIN: Ping_0132
TTU: TERTU_0899
CSA: Csal_2979
MMW: Mmwyl1_2779
TAU: Tola_2883
REH: H16_A1937(mtlD)
CTI: RALTA_A2838
BMA: BMAA0768
BMV: BMASAVP1_0581
BML: BMA10229_0692
BMN: BMA10247_A1646
BPS: BPSS1476
BPM: BURPS1710b_A0508
BPL: BURPS1106A_A1999
BPD: BURPS668_A2094
BCM: Bcenmc03_5663
BAC: BamMC406_5134
BPY: Bphyt_4721 Bphyt_5747
BGL: bglu_2g01890
BPT: Bpet3940
POL: Bpro_3970
VEI: Veis_3560
VAP: Vapar_2884
MES: Meso_4497
SME: SM_b20749(uxuB)
SMD: Smed_4245
ATU: Atu3530(uxuB)
ATC: AGR_L_2604
ARA: Arad_8887(uxuB)
AVI: Avi_3896(uxuB)
RET: RHE_CH00089(uxuB)
REC: RHECIAT_CH0000093(uxuB)
RLE: RL0098
RLT: Rleg2_4022
RLG: Rleg_4352
RHI: NGR_b20770
BME: BMEII0478
BMI: BMEA_B0790
BMF: BAB2_0426
BMB: BruAb2_0421
BMC: BAbS19_II04010
BOV: BOV_A0761
BCS: BCAN_B0825(mtlK)
BMR: BMI_II805
OAN: Oant_4096
BJA: blr6836(uxuB)
BBT: BBta_2118
AZC: AZC_3347
MNO: Mnod_0976
CCS: CCNA_01554
CAK: Caul_1753
PZU: PHZ_c2458(mtlK)
SIL: SPO1724(uxuB)
SIT: TM1040_3866
RSP: RSP_0480(uxuB)
RSH: Rsph17029_2132
RSQ: Rsph17025_2405
RSK: RSKD131_1813
RDE: RD1_2933(uxuB)
HBA: Hbal_2811
ZMN: Za10_1741
NAR: Saro_3524
SWI: Swit_1886
ACR: Acry_1859
GDI: GDI_0886(mtlK)
GDJ: Gdia_1133 Gdia_3090
APT: APA01_40070
LLA: L0241(uxuB)
LLK: LLKF_1789(uxuB)
LLC: LACR_1746
LLM: llmg_0858(uxuB)
LBR: LVIS_0139
LRH: LGG_00057(uxuB)
LRL: LC705_00048(uxuB)
CBE: Cbei_4083
CPY: Cphy_1062
CCE: Ccel_0139
ATE: Athe_0855
APR: Apre_1602
EEL: EUBELI_20594
MTA: Moth_0429
MSM: MSMEG_5576
MMI: MMAR_0571
CGT: cgR_2395
CEF: CE2378
RHA: RHA1_ro02788
ROP: ROP_24050 ROP_25060
ART: Arth_0503
AAU: AAur_0528
ACH: Achl_0788 Achl_1006 Achl_1716
RSA: RSal33209_3419
BCV: Bcav_0601 Bcav_3317
BFA: Bfae_31040
JDE: Jden_2406
XCE: Xcel_2666
TCU: Tcur_4796
FRE: Franean1_3198
NML: Namu_4288
KRA: Krad_0583
SEN: SACE_4940 SACE_5054(mtlD)
SVI: Svir_07170
AMI: Amir_5059
BLN: Blon_0668
BHY: BHWA1_02241(mtlD2)
PHE: Phep_3764
RBA: RB2403(uxuB)
TMA: TM0068
TPT: Tpet_0856
TRQ: TRQ2_0879
TNA: CTN_0625
TNP: Tnap_0698
Taxonomy
Reference
  Authors
  Title


  Journal
  Organism
 1  [PMID:14401695]
HICKMAN J, ASHWELL G.
Uronic acid metabolism in bacteria. II. Purification and properties
of D-altronic acid and D-mannonic acid dehydrogenases in Escherichia
coli.
J. Biol. Chem. 235 (1960) 1566-70.
Escherichia coli [GN:eco]
Reference
  Authors
  Title

  Journal
  Organism
 2  [PMID:14409051]
KILGORE WW, STARR MP.
Catabolism of galacturonic and glucuronic acids by Erwinia
carotovora.
J. Biol. Chem. 234 (1959) 2227-35.
Erwinia carotovora [GN:eca]
Other DBs ExplorEnz - The Enzyme Database: 1.1.1.57
IUBMB Enzyme Nomenclature: 1.1.1.57
ExPASy - ENZYME nomenclature database: 1.1.1.57
BRENDA, the Enzyme Database: 1.1.1.57
CAS: 9028-44-8
DBGET integrated database retrieval system