| Entry |
|
|---|
| Name |
alcohol dehydrogenase [NAD(P)+];
retinal reductase;
aldehyde reductase (NADPH/NADH);
alcohol dehydrogenase [NAD(P)] |
|---|
| Class |
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
 |
|---|
| Sysname |
alcohol:NAD(P)+ oxidoreductase |
|---|
| Reaction(IUBMB) |
an alcohol + NAD(P)+ = an aldehyde + NAD(P)H + H+ [RN:R07326 R07328] |
|---|
| Reaction(KEGG) |
R07326 > R00623 R00754;
R07328 > R00625 R00746
 |
|---|
| Substrate |
alcohol [CPD:C00069];
NAD+ [CPD:C00003];
NADP+ [CPD:C00006] |
|---|
| Product |
aldehyde [CPD:C00071];
NADH [CPD:C00004];
NADPH [CPD:C00005];
H+ [CPD:C00080] |
|---|
| Comment |
Reduces aliphatic aldehydes of carbon chain length from 2 to 14,
with greatest activity on C4, C6 and C8 aldehydes; also reduces
retinal to retinol. |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:4300551]
Fidge NH, Goodman DS.
The enzymatic reducation of retinal to retinol in rat intestine.
J. Biol. Chem. 243 (1968) 4372-9.
Rattus norvegicus [GN:rno] |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 1.1.1.71
IUBMB Enzyme Nomenclature: 1.1.1.71
ExPASy - ENZYME nomenclature database: 1.1.1.71
UM-BBD (Biocatalysis/Biodegradation Database): 1.1.1.71
BRENDA, the Enzyme Database: 1.1.1.71
CAS: 37250-10-5 |
|---|
