| Entry |
|
|---|
| Name |
glycerol-3-phosphate dehydrogenase (NAD+);
alpha-glycerol phosphate dehydrogenase (NAD+);
alpha-glycerophosphate dehydrogenase (NAD+);
glycerol 1-phosphate dehydrogenase;
glycerol phosphate dehydrogenase (NAD+);
glycerophosphate dehydrogenase (NAD+);
hydroglycerophosphate dehydrogenase;
L-alpha-glycerol phosphate dehydrogenase;
L-alpha-glycerophosphate dehydrogenase;
L-glycerol phosphate dehydrogenase;
L-glycerophosphate dehydrogenase (ambiguous);
NAD+-alpha-glycerophosphate dehydrogenase;
NAD+-dependent glycerol phosphate dehydrogenase;
NAD+-dependent glycerol-3-phosphate dehydrogenase;
NAD+-L-glycerol-3-phosphate dehydrogenase;
NAD+-linked glycerol 3-phosphate dehydrogenase;
NADH-dihydroxyacetone phosphate reductase;
glycerol-3-phosphate dehydrogenase (NAD+);
L-glycerol-3-phosphate dehydrogenase (ambiguous) |
|---|
| Class |
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
 |
|---|
| Sysname |
sn-glycerol-3-phosphate:NAD+ 2-oxidoreductase |
|---|
| Reaction(IUBMB) |
sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH + H+
[RN:R00842] |
|---|
| Reaction(KEGG) |
R00842
 |
|---|
| Substrate |
sn-glycerol 3-phosphate [CPD:C00093];
NAD+ [CPD:C00003] |
|---|
| Product |
glycerone phosphate [CPD:C00111];
NADH [CPD:C00004];
H+ [CPD:C00080] |
|---|
| Comment |
Also acts on propane-1,2-diol phosphate and glycerone sulfate (but
with a much lower affinity). |
|---|
| Pathway |
ec00564 Glycerophospholipid metabolism |
|---|
| Orthology |
K00006 glycerol-3-phosphate dehydrogenase (NAD+) |
|---|
| Genes |
HSA: 23171(GPD1L) 2819(GPD1)
PTR: 741054(GPD1)
MCC: 707723 713384(GPD1)
MMU: 14555(Gpd1) 333433(Gpd1l)
RNO: 363159(Gpd1l) 60666(Gpd1)
CFA: 485626(GPD1L) 607942(GPD1)
BTA: 514456(GPD1L) 525042(GPD1)
SSC: 100153250(GPD1)
ECB: 100052204 100057124
MDO: 100021123
OAA: 100077586 100085954
GGA: 420664(GPD1L) 424263(GPD1)
TGU: 100219677 100219837 100225600
XLA: 379962(gpd1l) 399227(gpd1) 444456
XTR: 394623(gpd1l) 448519(gpd1)
DRE: 325181(gpd1b) 406615(gpd1) 449663(gpd1l) 550404(gpd1a)
BFO: BRAFLDRAFT_226348
CIN: 100181104
DME: Dmel_CG3215 Dmel_CG9042(Gpdh)
DPO: Dpse_GA16715
DAN: Dana_GF13315 Dana_GF15589(Dana_Gpdh)
DER: Dere_GG20063 Dere_GG25104(Dere_Gpdh)
DPE: Dper_GL11294 Dper_GL19044(Dper_Gpdh)
DSE: Dsec_GM15578
DSI: Dsim_GD23370(Dsim_Gpdh) Dsim_GD25078
DWI: Dwil_GK14706(Dwil_Gpdh) Dwil_GK19593
DYA: Dyak_GE11600 Dyak_GE25734(Dyak_Gpdh)
DGR: Dgri_GH11012 Dgri_GH23061
DMO: Dmoj_GI17532 Dmoj_GI21131
DVI: Dvir_GJ15413(Dvir_Gpdh) Dvir_GJ20981
AGA: AgaP_AGAP007593
AAG: AaeL_AAEL001593
CQU: CpipJ_CPIJ000232
AME: 726445(Gpdh)
NVI: 100123685(NV14099) 100123687(NV14101)
TCA: 663884
API: 100160658(ACYPI001939)
PHU: Phum_PHUM174010
ISC: IscW_ISCW005254
CEL: F47G4.3(gpdh-1) K11H3.1(gpdh-2)
CBR: CBG09958(Cbr-gpdh-2) CBG18871(Cbr-gpdh-1)
BMY: Bm1_45570
SMM: Smp_030500.1
NVE: NEMVE_v1g156868 NEMVE_v1g211642
HMG: 100200028
TAD: TRIADDRAFT_38307
ATH: AT5G40610
POP: POPTR_908191
RCU: RCOM_0531780
VVI: 100261224
OSA: 4323847(Os01g0971600)
SBI: SORBI_03g047310
ZMA: 100284124
PPP: PHYPADRAFT_186920
CRE: CHLREDRAFT_96789
CME: CMD113C
SCE: YDL022W(GPD1) YOL059W(GPD2)
AGO: AGOS_ADR311C
KLA: KLLA0C04004g
LTH: KLTH0F06622g
DHA: DEHA2F09372g
PIC: PICST_83071(GPD2) PICST_90446(GPD1)
PPA: PAS_chr2-2_0111
PGU: PGUG_01519 PGUG_05498
VPO: Kpol_1037p2
LEL: LELG_02389 LELG_04817
ZRO: ZYRO0A05390g
CAL: CaO19.1756(GPD1) CaO19.691(GPD2)
CTP: CTRG_02011 CTRG_02898
CDU: CD36_24300(GPD1) CD36_62130
CGR: CAGL0C05137g CAGL0K01683g
YLI: YALI0B02948g
CLU: CLUG_03347 CLUG_05143
SPO: SPAC23D3.04c(gpd2) SPBC215.05(gpd1)
NCR: NCU00742
MGR: MGG_00067(MG00067.4)
FGR: FG05023.1
ANI: AN0351.2 AN6792.2
AFM: AFUA_1G02150 AFUA_2G08250
AOR: AO090005000883 AO090011000879
ANG: An01g06110 An15g07390
AFV: AFLA_046760 AFLA_081330
ACT: ACLA_032280 ACLA_080090
PCS: Pc20g06370 Pc22g22110
NFI: NFIA_022500 NFIA_083910
CIM: CIMG_09984
URE: UREG_06029
SSL: SS1G_12794
BFU: BC1G_05277
PNO: SNOG_03768
CNE: CNA01100 CNC02480
CNB: CNBA1070 CNBC4750
MPR: MPER_10941
UMA: UM00555.1
MGL: MGL_2451
ECU: ECU05_0270
PFA: PF11_0157 PFL0780w
PFD: PFDG_02150
PFH: PFHG_03289 PFHG_04100
PYO: PY00789 PY05585
PCB: PC000289.03.0
PBE: PB000629.01.0 PB001193.02.0
PKN: PKH_091190 PKH_143330
PVX: PVX_091380 PVX_123490
TAN: TA21330
TPV: TP01_0302
BBO: BBOV_IV004480(23.m06005)
CPV: cgd2_210
CHO: Chro.20028
TGO: TGME49_107570
TBR: Tb927.8.3530
LMA: LmjF10.0510(GPD)
LIF: LinJ10.0850
LBZ: LbrM10_V2.0640
TVA: TVAG_230610 TVAG_382880
PTI: PHATR_36821
TPS: THAPSDRAFT_260786
 |
|---|
Reference
Authors
Title
Journal
|
1
Baranowski, T.
alpha-Glycerophosphate dehydrogenase.
In: Boyer, P.D., Lardy, H. and Myrback, K. (Eds.), The Enzymes, 2nd
ed., vol. 7, Academic Press, New York, 1963, p. 85-96. |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:4307630]
Brosemer RW, Kuhn RW.
Comparative structural properties of honeybee and rabbit
alpha-glycerophosphate dehydrogenases.
Biochemistry. 8 (1969) 2095-105.
Apis mellifera [GN:ame], Oryctolagus cuniculus |
|---|
Reference
Authors
Title
Journal
Organism
|
3 [PMID:4340553]
O'Brien SJ, MacIntyre RJ.
The -glycerophosphate cycle in Drosophila melanogaster. I.
Biochemical and developmental aspects.
Biochem. Genet. 7 (1972) 141-61.
Drosophila melanogaster [GN:dme] |
|---|
Reference
Authors
Title
Journal
Organism
|
4 [PMID:4200180]
Warkentin DL, Fondy TP.
Isolation and characterization of cytoplasmic L-glycerol-3-phosphate
dehydrogenase from rabbit-renal-adipose tissue and its comparison
with the skeletal-muscle enzyme.
Eur. J. Biochem. 36 (1973) 97-109.
Oryctolagus cuniculus |
|---|
Reference
Authors
Title
Journal
Organism
|
5 [PMID:1499720]
Albertyn J, van Tonder A, Prior BA.
Purification and characterization of glycerol-3-phosphate
dehydrogenase of Saccharomyces cerevisiae.
FEBS. Lett. 308 (1992) 130-2.
Saccharomyces cerevisiae [GN:sce] |
|---|
Reference
Authors
Title
Journal
Organism
|
6 [PMID:7671141]
Koekemoer TC, Litthauer D, Oelofsen W.
Isolation and characterization of adipose tissue
glycerol-3-phosphate dehydrogenase.
Int. J. Biochem. Cell. Biol. 27 (1995) 625-32.
Homo sapiens [GN:hsa] |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 1.1.1.8
IUBMB Enzyme Nomenclature: 1.1.1.8
ExPASy - ENZYME nomenclature database: 1.1.1.8
BRENDA, the Enzyme Database: 1.1.1.8
CAS: 9075-65-4 |
|---|
