KEGG   ENZYME: 1.1.1.82Help
Entry
EC 1.1.1.82                 Enzyme                                 

Name malate dehydrogenase (NADP+);
NADP+-malic enzyme;
NADP+-malate dehydrogenase;
malic dehydrogenase (nicotinamide adenine dinucleotide phosphate);
malate NADP+ dehydrogenase;
NADP+ malate dehydrogenase;
NADP+-linked malate dehydrogenase;
malate dehydrogenase (NADP+)
Class Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname (S)-malate:NADP+ oxidoreductase
Reaction(IUBMB) (S)-malate + NADP+ = oxaloacetate + NADPH + H+ [RN:R00343]
Reaction(KEGG) R00343
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Substrate (S)-malate [CPD:C00149];
NADP+ [CPD:C00006]
Product oxaloacetate [CPD:C00036];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Effector hn [CPD:C00205]
Comment Activated by light.
Pathway PATH: ec00620  Pyruvate metabolism
PATH: ec00710  Carbon fixation in photosynthetic organisms
PATH: ec01100  Metabolic pathways
Orthology KO: K00051  malate dehydrogenase (NADP+)
Genes VFI: VF_1252(allD)
CSA: Csal_1771
VEI: Veis_0890
CGL: NCgl0631(cgl0661)
MJA: MJ0490
MMP: MMP0645(mdh)
Taxonomy
Structures PDB: 1CIV  7MDH  
Reference
  Authors
  Title



  Journal
  Organism
1  [PMID:5689906]
Connelly JL, Danner DJ, Bowden JA.
Branched chain alpha-keto acid metabolism. I. Isolation,
purification, and partial characterization of bovine liver
alpha-ketoisocaproic:alpha-keto-beta-methylvaleric acid
dehydrogenase.
J. Biol. Chem. 243 (1968) 1198-203.
Bos taurus [GN:bta]
Reference
  Authors
  Title

  Journal
  Organism
2  [PMID:4397919]
Johnson HS.
NADP-malate dehydrogenase: photoactivation in leaves of plants with
Calvin cycle photosynthesis.
Biochem. Biophys. Res. Commun. 43 (1971) 703-9.
Zea mays [GN:zma]
Reference
  Authors
  Title


  Journal
  Organism
3  [PMID:4395182]
Johnson HS, Hatch MD.
Properties and regulation of leaf nicotinamide-adenine dinucleotide
phosphate-malate dehydrogenase and 'malic' enzyme in plants with the
C4-dicarboxylic acid pathway of photosynthesis.
Biochem. J. 119 (1970) 273-80.
Zea mays [GN:zma]
Other DBs ExplorEnz - The Enzyme Database: 1.1.1.82
IUBMB Enzyme Nomenclature: 1.1.1.82
ExPASy - ENZYME nomenclature database: 1.1.1.82
BRENDA, the Enzyme Database: 1.1.1.82
CAS: 37250-19-4

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