| Entry |
|
|---|
| Name |
malate dehydrogenase (NADP+);
NADP+-malic enzyme;
NADP+-malate dehydrogenase;
malic dehydrogenase (nicotinamide adenine dinucleotide phosphate);
malate NADP+ dehydrogenase;
NADP+ malate dehydrogenase;
NADP+-linked malate dehydrogenase;
malate dehydrogenase (NADP+) |
|---|
| Class |
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
 |
|---|
| Sysname |
(S)-malate:NADP+ oxidoreductase |
|---|
| Reaction(IUBMB) |
(S)-malate + NADP+ = oxaloacetate + NADPH + H+ [RN:R00343] |
|---|
| Reaction(KEGG) |
R00343
 |
|---|
| Substrate |
(S)-malate [CPD:C00149];
NADP+ [CPD:C00006] |
|---|
| Product |
oxaloacetate [CPD:C00036];
NADPH [CPD:C00005];
H+ [CPD:C00080] |
|---|
| Effector |
hn [CPD:C00205] |
|---|
| Comment |
Activated by light. |
|---|
| Pathway |
PATH: ec00620 Pyruvate metabolism
PATH: ec00710 Carbon fixation in photosynthetic organisms
PATH: ec01100 Metabolic pathways |
|---|
| Orthology |
KO: K00051 malate dehydrogenase (NADP+) |
|---|
| Genes |
VFI: VF_1252(allD)
CSA: Csal_1771
VEI: Veis_0890
CGL: NCgl0631(cgl0661)
MJA: MJ0490
MMP: MMP0645(mdh)
 |
|---|
| Structures |
PDB: 1CIV 7MDH |
|---|
Reference
Authors
Title
Journal
Organism
|
1 [PMID:5689906]
Connelly JL, Danner DJ, Bowden JA.
Branched chain alpha-keto acid metabolism. I. Isolation,
purification, and partial characterization of bovine liver
alpha-ketoisocaproic:alpha-keto-beta-methylvaleric acid
dehydrogenase.
J. Biol. Chem. 243 (1968) 1198-203.
Bos taurus [GN:bta] |
|---|
Reference
Authors
Title
Journal
Organism
|
2 [PMID:4397919]
Johnson HS.
NADP-malate dehydrogenase: photoactivation in leaves of plants with
Calvin cycle photosynthesis.
Biochem. Biophys. Res. Commun. 43 (1971) 703-9.
Zea mays [GN:zma] |
|---|
Reference
Authors
Title
Journal
Organism
|
3 [PMID:4395182]
Johnson HS, Hatch MD.
Properties and regulation of leaf nicotinamide-adenine dinucleotide
phosphate-malate dehydrogenase and 'malic' enzyme in plants with the
C4-dicarboxylic acid pathway of photosynthesis.
Biochem. J. 119 (1970) 273-80.
Zea mays [GN:zma] |
|---|
| Other DBs |
ExplorEnz - The Enzyme Database: 1.1.1.82
IUBMB Enzyme Nomenclature: 1.1.1.82
ExPASy - ENZYME nomenclature database: 1.1.1.82
BRENDA, the Enzyme Database: 1.1.1.82
CAS: 37250-19-4 |
|---|
